Tests Catalogs

CHROMIUM SERUM

LAB3761

Collect

Royal blue (no additive).

Patient Preparation

Diet, medication, and nutritional supplements may introduce interfering substances. Patients should be encouraged to discontinue nutritional supplements, vitamins, minerals, and non-essential over-the-counter medications (upon the advice of their physician).

Specimen Preparation

Centrifuge; do not allow serum to remain on cells. Transfer 2 mL serum to an ARUP Trace Element-Free Transport Tube (ARUP supply #43116). Available online through eSupply using ARUP Connect™ or contact ARUP Client Services at (800) 522-2787. (Min: 0.5 mL)

Unacceptable Conditions

Separator tubes. Specimens that are not separated from the red cells or clot within 6 hours.

Storage/Transport Temperature

Room temperature. Also acceptable: Refrigerated or frozen.

Stability (from collection to initiation)

If the specimen is drawn and stored in the appropriate container, the trace element values do not change with time.

Notes

Elevated results from noncertified trace element-free tubes may be due to contamination.  Elevated concentrations of trace elements in serum should be confirmed with a second specimen collected in a trace element-free tube, such as royal blue sterile tube (no additive).

Performed

Tue, Thu, Sat

Methodology

Quantitative Inductively Coupled Plasma-Mass Spectrometry

Reported

1-4 days

Synonyms

  • LAB3761
  • CR S

Additional Technical Information

Ordering Recommendations

Preferred test for evaluating metal ion release from metal-on-metal joint arthroplasty. May be useful in the assessment of deficiency or overload. For the assessment of hexavalent chromium exposure, chromium in blood or RBCs is preferred.

Reference Interval

Less than or equal to 5.0 µg/L

Interpretive Data

Serum chromium is the preferred specimen type for evaluating metal ion release from metal-on-metal joint arthroplasty. Serum chromium levels may be increased in asymptomatic patients with metal-on-metal prosthetics and should be considered in the context of the overall clinical scenario. The form of chromium greatly influences distribution. Trivalent chromium resides in the plasma and is usually not of clinical importance. Hexavalent chromium is considered highly toxic; however, chromium serum levels should not be used to assess toxic exposures to hexavalent chromium as it is predominately taken up and retained by red blood cells. Symptoms associated with chromium toxicity vary based on route of exposure and dose, and may include dermatitis, impairment of pulmonary function, gastroenteritis, hepatic necrosis, bleeding, and acute tubular necrosis.

CPT Codes

82495
Collection

LAB3761

Collect

Royal blue (no additive).

Patient Preparation

Diet, medication, and nutritional supplements may introduce interfering substances. Patients should be encouraged to discontinue nutritional supplements, vitamins, minerals, and non-essential over-the-counter medications (upon the advice of their physician).

Specimen Preparation

Centrifuge; do not allow serum to remain on cells. Transfer 2 mL serum to an ARUP Trace Element-Free Transport Tube (ARUP supply #43116). Available online through eSupply using ARUP Connect™ or contact ARUP Client Services at (800) 522-2787. (Min: 0.5 mL)

Unacceptable Conditions

Separator tubes. Specimens that are not separated from the red cells or clot within 6 hours.

Storage/Transport Temperature

Room temperature. Also acceptable: Refrigerated or frozen.

Stability (from collection to initiation)

If the specimen is drawn and stored in the appropriate container, the trace element values do not change with time.

Notes

Elevated results from noncertified trace element-free tubes may be due to contamination.  Elevated concentrations of trace elements in serum should be confirmed with a second specimen collected in a trace element-free tube, such as royal blue sterile tube (no additive).
Ordering

Performed

Tue, Thu, Sat

Methodology

Quantitative Inductively Coupled Plasma-Mass Spectrometry

Reported

1-4 days

Synonyms

  • LAB3761
  • CR S

Additional Technical Information

Ordering Recommendations

Preferred test for evaluating metal ion release from metal-on-metal joint arthroplasty. May be useful in the assessment of deficiency or overload. For the assessment of hexavalent chromium exposure, chromium in blood or RBCs is preferred.
Result Interpretation

Reference Interval

Less than or equal to 5.0 µg/L

Interpretive Data

Serum chromium is the preferred specimen type for evaluating metal ion release from metal-on-metal joint arthroplasty. Serum chromium levels may be increased in asymptomatic patients with metal-on-metal prosthetics and should be considered in the context of the overall clinical scenario. The form of chromium greatly influences distribution. Trivalent chromium resides in the plasma and is usually not of clinical importance. Hexavalent chromium is considered highly toxic; however, chromium serum levels should not be used to assess toxic exposures to hexavalent chromium as it is predominately taken up and retained by red blood cells. Symptoms associated with chromium toxicity vary based on route of exposure and dose, and may include dermatitis, impairment of pulmonary function, gastroenteritis, hepatic necrosis, bleeding, and acute tubular necrosis.

Administrative

CPT Codes

82495

CHROMIUM/COBALT JOINT FLUID

LAB3761

Collect

Royal blue (no additive).

Patient Preparation

Diet, medication, and nutritional supplements may introduce interfering substances. Patients should be encouraged to discontinue nutritional supplements, vitamins, minerals, and non-essential over-the-counter medications (upon the advice of their physician).

Specimen Preparation

Centrifuge; do not allow serum to remain on cells. Transfer 2 mL serum to an ARUP Trace Element-Free Transport Tube (ARUP supply #43116). Available online through eSupply using ARUP Connect™ or contact ARUP Client Services at (800) 522-2787. (Min: 0.5 mL)

Unacceptable Conditions

Separator tubes. Specimens that are not separated from the red cells or clot within 6 hours.

Storage/Transport Temperature

Room temperature. Also acceptable: Refrigerated or frozen.

Stability (from collection to initiation)

If the specimen is drawn and stored in the appropriate container, the trace element values do not change with time.

Notes

Elevated results from noncertified trace element-free tubes may be due to contamination.  Elevated concentrations of trace elements in serum should be confirmed with a second specimen collected in a trace element-free tube, such as royal blue sterile tube (no additive).

Performed

Tue, Thu, Sat

Methodology

Quantitative Inductively Coupled Plasma-Mass Spectrometry

Reported

1-4 days

Synonyms

  • LAB3761
  • CR S

Additional Technical Information

Ordering Recommendations

Preferred test for evaluating metal ion release from metal-on-metal joint arthroplasty. May be useful in the assessment of deficiency or overload. For the assessment of hexavalent chromium exposure, chromium in blood or RBCs is preferred.

Reference Interval

Less than or equal to 5.0 µg/L

Interpretive Data

Serum chromium is the preferred specimen type for evaluating metal ion release from metal-on-metal joint arthroplasty. Serum chromium levels may be increased in asymptomatic patients with metal-on-metal prosthetics and should be considered in the context of the overall clinical scenario. The form of chromium greatly influences distribution. Trivalent chromium resides in the plasma and is usually not of clinical importance. Hexavalent chromium is considered highly toxic; however, chromium serum levels should not be used to assess toxic exposures to hexavalent chromium as it is predominately taken up and retained by red blood cells. Symptoms associated with chromium toxicity vary based on route of exposure and dose, and may include dermatitis, impairment of pulmonary function, gastroenteritis, hepatic necrosis, bleeding, and acute tubular necrosis.

CPT Codes

82495
Collection

LAB3761

Collect

Royal blue (no additive).

Patient Preparation

Diet, medication, and nutritional supplements may introduce interfering substances. Patients should be encouraged to discontinue nutritional supplements, vitamins, minerals, and non-essential over-the-counter medications (upon the advice of their physician).

Specimen Preparation

Centrifuge; do not allow serum to remain on cells. Transfer 2 mL serum to an ARUP Trace Element-Free Transport Tube (ARUP supply #43116). Available online through eSupply using ARUP Connect™ or contact ARUP Client Services at (800) 522-2787. (Min: 0.5 mL)

Unacceptable Conditions

Separator tubes. Specimens that are not separated from the red cells or clot within 6 hours.

Storage/Transport Temperature

Room temperature. Also acceptable: Refrigerated or frozen.

Stability (from collection to initiation)

If the specimen is drawn and stored in the appropriate container, the trace element values do not change with time.

Notes

Elevated results from noncertified trace element-free tubes may be due to contamination.  Elevated concentrations of trace elements in serum should be confirmed with a second specimen collected in a trace element-free tube, such as royal blue sterile tube (no additive).
Ordering

Performed

Tue, Thu, Sat

Methodology

Quantitative Inductively Coupled Plasma-Mass Spectrometry

Reported

1-4 days

Synonyms

  • LAB3761
  • CR S

Additional Technical Information

Ordering Recommendations

Preferred test for evaluating metal ion release from metal-on-metal joint arthroplasty. May be useful in the assessment of deficiency or overload. For the assessment of hexavalent chromium exposure, chromium in blood or RBCs is preferred.
Result Interpretation

Reference Interval

Less than or equal to 5.0 µg/L

Interpretive Data

Serum chromium is the preferred specimen type for evaluating metal ion release from metal-on-metal joint arthroplasty. Serum chromium levels may be increased in asymptomatic patients with metal-on-metal prosthetics and should be considered in the context of the overall clinical scenario. The form of chromium greatly influences distribution. Trivalent chromium resides in the plasma and is usually not of clinical importance. Hexavalent chromium is considered highly toxic; however, chromium serum levels should not be used to assess toxic exposures to hexavalent chromium as it is predominately taken up and retained by red blood cells. Symptoms associated with chromium toxicity vary based on route of exposure and dose, and may include dermatitis, impairment of pulmonary function, gastroenteritis, hepatic necrosis, bleeding, and acute tubular necrosis.

Administrative

CPT Codes

82495

CHROMOGENIC FACTOR Xa

LAB3104

Collect

One 5 mL Lt.blue (Citrated Blood) .

Unacceptable Conditions

Non-frozen samples, serum, plasma OTHER THAN citrated.

Storage/Transport Temperature

Internal: Deliver to lab immediatley
Offsite: 1 mL citrated plasma

Spin and separate plasma and ship to lab frozen.

Stability (from collection to initiation)

Frozen ASAP.

Remarks

Ship frozen.

Performed by

Duke Medical Center

Performed

Varies

Methodology

Chromogenic

Reported

In 4 days

Synonyms

  • LAB3104

Performed by

Duke Medical Center

CPT Codes

85260

Collection

LAB3104

Collect

One 5 mL Lt.blue (Citrated Blood) .

Unacceptable Conditions

Non-frozen samples, serum, plasma OTHER THAN citrated.

Storage/Transport Temperature

Internal: Deliver to lab immediatley
Offsite: 1 mL citrated plasma

Spin and separate plasma and ship to lab frozen.

Stability (from collection to initiation)

Frozen ASAP.

Remarks

Ship frozen.

Performed by

Duke Medical Center

Ordering

Performed

Varies

Methodology

Chromogenic

Reported

In 4 days

Synonyms

  • LAB3104
Result Interpretation

Performed by

Duke Medical Center

Administrative

CPT Codes

85260

CHROMOGRANIN A - SERUM

LAB3008

Collect

Serum separator tube or plain red.

Specimen Preparation

Allow serum specimen to clot completely at room temperature. Transfer 1 mL serum to an ARUP Standard Transport Tube. (Min: 0.5 mL)

Unacceptable Conditions

Plasma.

Storage/Transport Temperature

Frozen.

Stability (from collection to initiation)

After separation from cells: Ambient: 48 hours; Refrigerated: 2 weeks; Frozen: 6 weeks

Performed

Mon, Wed, Fri

Methodology

Quantitative Enzyme Immunoassay

Reported

1-6 days

Synonyms

  • LAB3008
  • CGA

Ordering Recommendations

Assay aids in monitoring but is not recommended for diagnosis of carcinoid tumors. Assay may be useful in monitoring nonsecretory sympathetic and parasympathetic  neuroendocrine tumors.

Reference Interval

Effective May 16, 2011

0-95 ng/mL

Interpretive Data

This test is performed using the Cisbio CGA-ELISA-US kit. Results obtained with different methods or kits cannot be used interchangeably.

CPT Codes

86316
Collection

LAB3008

Collect

Serum separator tube or plain red.

Specimen Preparation

Allow serum specimen to clot completely at room temperature. Transfer 1 mL serum to an ARUP Standard Transport Tube. (Min: 0.5 mL)

Unacceptable Conditions

Plasma.

Storage/Transport Temperature

Frozen.

Stability (from collection to initiation)

After separation from cells: Ambient: 48 hours; Refrigerated: 2 weeks; Frozen: 6 weeks
Ordering

Performed

Mon, Wed, Fri

Methodology

Quantitative Enzyme Immunoassay

Reported

1-6 days

Synonyms

  • LAB3008
  • CGA

Ordering Recommendations

Assay aids in monitoring but is not recommended for diagnosis of carcinoid tumors. Assay may be useful in monitoring nonsecretory sympathetic and parasympathetic  neuroendocrine tumors.
Result Interpretation

Reference Interval

Effective May 16, 2011

0-95 ng/mL

Interpretive Data

This test is performed using the Cisbio CGA-ELISA-US kit. Results obtained with different methods or kits cannot be used interchangeably.

Administrative

CPT Codes

86316

CITRIC ACID, URINE

LAB377

Collect

24-hour urine. Refrigerate during collection. Also acceptable: Random urine.

Specimen Preparation

Adjust pH to less than or equal to 2 by adding 6M HCl. Transfer a 4 mL aliquot of urine to an ARUP Standard Transport Tube. (Min: 0.5 mL) Record total volume, collection time interval, and pH on transport tube and test request form. Also acceptable: Specimens previously preserved with boric acid.

Storage/Transport Temperature

Refrigerated.

Stability (from collection to initiation)

Ambient: 8 hours; Refrigerated: 1 week; Frozen: Indefinitely

Performed

Sun-Sat

Methodology

Quantitative Enzymatic

Reported

Within 24 hours

Synonyms

  • Citrate, Urine
  • LAB377
  • CITRIC U

Reference Interval

Components
Reference Interval
Citric Acid, Urine - per 24h18 years and older: 320-1240 mg/d
Citric Acid/Creatinine Ratio, Urine1 year and older: greater than or equal to 150 mg/g.

CPT Codes

82507
Collection

LAB377

Collect

24-hour urine. Refrigerate during collection. Also acceptable: Random urine.

Specimen Preparation

Adjust pH to less than or equal to 2 by adding 6M HCl. Transfer a 4 mL aliquot of urine to an ARUP Standard Transport Tube. (Min: 0.5 mL) Record total volume, collection time interval, and pH on transport tube and test request form. Also acceptable: Specimens previously preserved with boric acid.

Storage/Transport Temperature

Refrigerated.

Stability (from collection to initiation)

Ambient: 8 hours; Refrigerated: 1 week; Frozen: Indefinitely
Ordering

Performed

Sun-Sat

Methodology

Quantitative Enzymatic

Reported

Within 24 hours

Synonyms

  • Citrate, Urine
  • LAB377
  • CITRIC U
Result Interpretation

Reference Interval

Components
Reference Interval
Citric Acid, Urine - per 24h18 years and older: 320-1240 mg/d
Citric Acid/Creatinine Ratio, Urine1 year and older: greater than or equal to 150 mg/g.

Administrative

CPT Codes

82507

CKIT [D816V] MUTATION BY PCR

LAB4380

Collect

Lavender (EDTA) OR bone marrow (EDTA) OR tissue.

Specimen Preparation

Whole blood: Transport 5 mL (Min: 1 mL) OR Bone marrow: Transport 3 mL (Min: 1 mL) OR Fresh tissue: Freeze immediately. Transport 100 mg or 0.5-2.0 cm3 tissue. OR FFPE tumor tissue: Formalin fix (10 percent neutral buffered formalin) and paraffin embed tissue. Protect from excessive heat. Transport tissue block or four 10-micron shavings. Tissue block will be returned after testing.  Transport tissue (frozen, paraffin blocks) in a tissue transport kit (ARUP supply #47808) available online through eSupply using ARUP Connect™or contact ARUP Client Services at (800) 522-2787.

Unacceptable Conditions

Whole blood OR Bone marrow: Frozen specimens. Clotted or grossly hemolyzed specimens. FFPE tumor tissue: Specimens fixed/processed in alternative fixatives or heavy metal fixatives (B-4 or B-5) or tissue sections on slides. Decalcified specimens.

Storage/Transport Temperature

Whole blood OR Bone marrow: Refrigerated. Fresh tissue: Frozen on dry ice. FFPE tumor tissue: Room temperature or refrigerated. Ship in cooled container during summer months.

Stability (from collection to initiation)

Whole blood OR Bone marrow: Ambient: 24 hours; Refrigerated: 5 days; Frozen: Unacceptable
Fresh Tissue: Ambient: Unacceptable; Refrigerated: 2 hours; Frozen: 1 year
FFPE tumor tissue: Ambient: Indefinitely; Refrigerated: Indefinitely; Frozen: Unacceptable

Performed

DNA isolation: Sun-Sat
Assay: Mon, Wed, Fri

Methodology

Polymerase Chain Reaction

Reported

2-7 days

Synonyms

  • LAB4380

Additional Technical Information

Ordering Recommendations

Aids in the diagnosis of mastocytosis. Provide prognostic and predictive information for tyrosine kinase inhibitor (TKI) therapy planning.

Interpretive Data

Refer to report.

CPT Codes

81273
Collection

LAB4380

Collect

Lavender (EDTA) OR bone marrow (EDTA) OR tissue.

Specimen Preparation

Whole blood: Transport 5 mL (Min: 1 mL) OR Bone marrow: Transport 3 mL (Min: 1 mL) OR Fresh tissue: Freeze immediately. Transport 100 mg or 0.5-2.0 cm3 tissue. OR FFPE tumor tissue: Formalin fix (10 percent neutral buffered formalin) and paraffin embed tissue. Protect from excessive heat. Transport tissue block or four 10-micron shavings. Tissue block will be returned after testing.  Transport tissue (frozen, paraffin blocks) in a tissue transport kit (ARUP supply #47808) available online through eSupply using ARUP Connect™or contact ARUP Client Services at (800) 522-2787.

Unacceptable Conditions

Whole blood OR Bone marrow: Frozen specimens. Clotted or grossly hemolyzed specimens. FFPE tumor tissue: Specimens fixed/processed in alternative fixatives or heavy metal fixatives (B-4 or B-5) or tissue sections on slides. Decalcified specimens.

Storage/Transport Temperature

Whole blood OR Bone marrow: Refrigerated. Fresh tissue: Frozen on dry ice. FFPE tumor tissue: Room temperature or refrigerated. Ship in cooled container during summer months.

Stability (from collection to initiation)

Whole blood OR Bone marrow: Ambient: 24 hours; Refrigerated: 5 days; Frozen: Unacceptable
Fresh Tissue: Ambient: Unacceptable; Refrigerated: 2 hours; Frozen: 1 year
FFPE tumor tissue: Ambient: Indefinitely; Refrigerated: Indefinitely; Frozen: Unacceptable
Ordering

Performed

DNA isolation: Sun-Sat
Assay: Mon, Wed, Fri

Methodology

Polymerase Chain Reaction

Reported

2-7 days

Synonyms

  • LAB4380

Additional Technical Information

Ordering Recommendations

Aids in the diagnosis of mastocytosis. Provide prognostic and predictive information for tyrosine kinase inhibitor (TKI) therapy planning.
Result Interpretation

Interpretive Data

Refer to report.

Administrative

CPT Codes

81273

CKMB PANEL

LAB4380

Collect

Lavender (EDTA) OR bone marrow (EDTA) OR tissue.

Specimen Preparation

Whole blood: Transport 5 mL (Min: 1 mL) OR Bone marrow: Transport 3 mL (Min: 1 mL) OR Fresh tissue: Freeze immediately. Transport 100 mg or 0.5-2.0 cm3 tissue. OR FFPE tumor tissue: Formalin fix (10 percent neutral buffered formalin) and paraffin embed tissue. Protect from excessive heat. Transport tissue block or four 10-micron shavings. Tissue block will be returned after testing.  Transport tissue (frozen, paraffin blocks) in a tissue transport kit (ARUP supply #47808) available online through eSupply using ARUP Connect™or contact ARUP Client Services at (800) 522-2787.

Unacceptable Conditions

Whole blood OR Bone marrow: Frozen specimens. Clotted or grossly hemolyzed specimens. FFPE tumor tissue: Specimens fixed/processed in alternative fixatives or heavy metal fixatives (B-4 or B-5) or tissue sections on slides. Decalcified specimens.

Storage/Transport Temperature

Whole blood OR Bone marrow: Refrigerated. Fresh tissue: Frozen on dry ice. FFPE tumor tissue: Room temperature or refrigerated. Ship in cooled container during summer months.

Stability (from collection to initiation)

Whole blood OR Bone marrow: Ambient: 24 hours; Refrigerated: 5 days; Frozen: Unacceptable
Fresh Tissue: Ambient: Unacceptable; Refrigerated: 2 hours; Frozen: 1 year
FFPE tumor tissue: Ambient: Indefinitely; Refrigerated: Indefinitely; Frozen: Unacceptable

Performed

DNA isolation: Sun-Sat
Assay: Mon, Wed, Fri

Methodology

Polymerase Chain Reaction

Reported

2-7 days

Synonyms

  • LAB4380

Additional Technical Information

Ordering Recommendations

Aids in the diagnosis of mastocytosis. Provide prognostic and predictive information for tyrosine kinase inhibitor (TKI) therapy planning.

Interpretive Data

Refer to report.

CPT Codes

81273
Collection

LAB4380

Collect

Lavender (EDTA) OR bone marrow (EDTA) OR tissue.

Specimen Preparation

Whole blood: Transport 5 mL (Min: 1 mL) OR Bone marrow: Transport 3 mL (Min: 1 mL) OR Fresh tissue: Freeze immediately. Transport 100 mg or 0.5-2.0 cm3 tissue. OR FFPE tumor tissue: Formalin fix (10 percent neutral buffered formalin) and paraffin embed tissue. Protect from excessive heat. Transport tissue block or four 10-micron shavings. Tissue block will be returned after testing.  Transport tissue (frozen, paraffin blocks) in a tissue transport kit (ARUP supply #47808) available online through eSupply using ARUP Connect™or contact ARUP Client Services at (800) 522-2787.

Unacceptable Conditions

Whole blood OR Bone marrow: Frozen specimens. Clotted or grossly hemolyzed specimens. FFPE tumor tissue: Specimens fixed/processed in alternative fixatives or heavy metal fixatives (B-4 or B-5) or tissue sections on slides. Decalcified specimens.

Storage/Transport Temperature

Whole blood OR Bone marrow: Refrigerated. Fresh tissue: Frozen on dry ice. FFPE tumor tissue: Room temperature or refrigerated. Ship in cooled container during summer months.

Stability (from collection to initiation)

Whole blood OR Bone marrow: Ambient: 24 hours; Refrigerated: 5 days; Frozen: Unacceptable
Fresh Tissue: Ambient: Unacceptable; Refrigerated: 2 hours; Frozen: 1 year
FFPE tumor tissue: Ambient: Indefinitely; Refrigerated: Indefinitely; Frozen: Unacceptable
Ordering

Performed

DNA isolation: Sun-Sat
Assay: Mon, Wed, Fri

Methodology

Polymerase Chain Reaction

Reported

2-7 days

Synonyms

  • LAB4380

Additional Technical Information

Ordering Recommendations

Aids in the diagnosis of mastocytosis. Provide prognostic and predictive information for tyrosine kinase inhibitor (TKI) therapy planning.
Result Interpretation

Interpretive Data

Refer to report.

Administrative

CPT Codes

81273

CLOMIPRAMINE + METABOLITE

LAB3477

Collect

Plain red. Also acceptable: Lavender (K2 or K3EDTA) or pink (K2EDTA).

Patient Preparation

Timing of specimen collection: Pre-dose (trough) draw - At steady state concentration.

Specimen Preparation

Separate serum or plasma from cells within 2 hours of collection. Transfer 1 mL serum or plasma to an ARUP Standard Transport Tube. (Min: 0.5 mL)

Unacceptable Conditions

Whole blood. Gel separator tubes, light blue (citrate), or yellow (SPS or ACD solution).

Storage/Transport Temperature

Refrigerated.

Stability (from collection to initiation)

After separation from cells: Ambient: 5 days; Refrigerated: 2 weeks; Frozen: 6 months

Performed

Mon, Wed, Fri

Methodology

Quantitative Liquid Chromatography-Tandem Mass Spectrometry

Reported

1-5 days

Synonyms

  • Anafranil
  • LAB3477
  • CLOMIP

Ordering Recommendations

Optimize drug therapy and monitor patient adherence.

Reference Interval

Effective February 19, 2013
Therapeutic RangeTotal (clomipramine and norclomipramine): 220-500 ng/mL
Toxic LevelGreater than 900 ng/mL

Interpretive Data

The therapeutic range listed relates to the antidepressant characteristics of the drug. A therapeutic range for treating obsessive compulsive disorder is not well established. Toxic concentrations may cause anticholinergic effects, CNS depression, cardiac abnormalities, seizures and hypotension.

CPT Codes

80335 (Alt code: G0480)
Collection

LAB3477

Collect

Plain red. Also acceptable: Lavender (K2 or K3EDTA) or pink (K2EDTA).

Patient Preparation

Timing of specimen collection: Pre-dose (trough) draw - At steady state concentration.

Specimen Preparation

Separate serum or plasma from cells within 2 hours of collection. Transfer 1 mL serum or plasma to an ARUP Standard Transport Tube. (Min: 0.5 mL)

Unacceptable Conditions

Whole blood. Gel separator tubes, light blue (citrate), or yellow (SPS or ACD solution).

Storage/Transport Temperature

Refrigerated.

Stability (from collection to initiation)

After separation from cells: Ambient: 5 days; Refrigerated: 2 weeks; Frozen: 6 months
Ordering

Performed

Mon, Wed, Fri

Methodology

Quantitative Liquid Chromatography-Tandem Mass Spectrometry

Reported

1-5 days

Synonyms

  • Anafranil
  • LAB3477
  • CLOMIP

Ordering Recommendations

Optimize drug therapy and monitor patient adherence.
Result Interpretation

Reference Interval

Effective February 19, 2013
Therapeutic RangeTotal (clomipramine and norclomipramine): 220-500 ng/mL
Toxic LevelGreater than 900 ng/mL

Interpretive Data

The therapeutic range listed relates to the antidepressant characteristics of the drug. A therapeutic range for treating obsessive compulsive disorder is not well established. Toxic concentrations may cause anticholinergic effects, CNS depression, cardiac abnormalities, seizures and hypotension.

Administrative

CPT Codes

80335 (Alt code: G0480)

CLONAZEPAM

LAB466

Collect

Gray (Potassium Oxalate/Sodium Fluoride). Also acceptable: Plain Red, Green (Sodium Heparin), Lavender (K2 or K3EDTA) or pink (K2EDTA).

Patient Preparation

Timing of specimen collection: Pre-dose (trough) draw - At steady state concentration

Specimen Preparation

Separate serum or plasma from cells ASAP or within 2 hours of collection. Transfer 2 mL serum or plasma to an ARUP Standard Transport Tube. (Min: 1 mL)

Unacceptable Conditions

Gel separator tubes. Plasma or whole blood collected in light blue (sodium citrate). Hemolyzed specimens.

Storage/Transport Temperature

Refrigerated.

Stability (from collection to initiation)

After separation from cells: Ambient: 1 week; Refrigerated: 2 weeks; Frozen: 3 years (Avoid repeated freeze/thaw cycles).

Performed

Tue, Fri

Methodology

Quantitative Liquid Chromatography-Tandem Mass Spectrometry

Reported

1-5 days

Synonyms

  • Klonopin
  • LAB466

Ordering Recommendations

Optimize drug therapy and monitor patient adherence.

Reference Interval

Effective November 18, 2013
Dose-Related Range20-70 ng/mL - Dose (Adult) 1-8 mg/d
ToxicGreater than 80 ng/mL

Interpretive Data

Adverse effects may include drowsiness, headache, fatigue and ataxia.

CPT Codes

80346 (Alt code: G0480)
Collection

LAB466

Collect

Gray (Potassium Oxalate/Sodium Fluoride). Also acceptable: Plain Red, Green (Sodium Heparin), Lavender (K2 or K3EDTA) or pink (K2EDTA).

Patient Preparation

Timing of specimen collection: Pre-dose (trough) draw - At steady state concentration

Specimen Preparation

Separate serum or plasma from cells ASAP or within 2 hours of collection. Transfer 2 mL serum or plasma to an ARUP Standard Transport Tube. (Min: 1 mL)

Unacceptable Conditions

Gel separator tubes. Plasma or whole blood collected in light blue (sodium citrate). Hemolyzed specimens.

Storage/Transport Temperature

Refrigerated.

Stability (from collection to initiation)

After separation from cells: Ambient: 1 week; Refrigerated: 2 weeks; Frozen: 3 years (Avoid repeated freeze/thaw cycles).
Ordering

Performed

Tue, Fri

Methodology

Quantitative Liquid Chromatography-Tandem Mass Spectrometry

Reported

1-5 days

Synonyms

  • Klonopin
  • LAB466

Ordering Recommendations

Optimize drug therapy and monitor patient adherence.
Result Interpretation

Reference Interval

Effective November 18, 2013
Dose-Related Range20-70 ng/mL - Dose (Adult) 1-8 mg/d
ToxicGreater than 80 ng/mL

Interpretive Data

Adverse effects may include drowsiness, headache, fatigue and ataxia.

Administrative

CPT Codes

80346 (Alt code: G0480)

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