Tests Catalogs

CALPROTECTIN - FECAL

LAB3763

Collect

Stool.

Specimen Preparation

Transfer 5 g stool to an unpreserved stool transport vial (ARUP Supply #40910). Available online through eSupply using ARUP Connect™ or contact ARUP Client Services at (800) 522-2787. (Min: 1 g)

Unacceptable Conditions

Specimens in media or preservatives.

Storage/Transport Temperature

Refrigerated.

Stability (from collection to initiation)

Ambient: 11 days; Refrigerated: 11 days; Frozen: 1 year

Notes

Fecal Calprotectin is an indicator of the presence of neutrophils in stool and is not specific for IBD. Other intestinal ailments including GI infections and colorectal cancer can result in elevated concentrations of calprotectin. The diagnosis of IBD cannot be established solely on the basis of a positive calprotectin result. Patients with IBD fluctuate between active and inactive stages of disease. Calprotectin results may also fluctuate. GI bleeding of as much as 100 mL per day will increase the fecal calprotectin concentration by only 15 µg/g.

Performed

Sun-Sat

Methodology

Quantitative Enzyme-Linked Immunosorbent Assay

Reported

1-3 days

Synonyms

  • LAB3763
  • CALPRO

Additional Technical Information

Ordering Recommendations

Aid in differentiation of inflammatory bowel disease (IBD) from irritable bowel syndrome (IBS) and other functional disorders of the gastrointestinal (GI) system. Aid in monitoring IBD and prediction of relapse.

Reference Interval

Effective August 15, 2016
50 µg/g or less: Normal
51-120 µg/g: Borderline elevated, test should be re-evaluated in 4-6 weeks.
121 µg/g or greater: Abnormal

CPT Codes

83993
Collection

LAB3763

Collect

Stool.

Specimen Preparation

Transfer 5 g stool to an unpreserved stool transport vial (ARUP Supply #40910). Available online through eSupply using ARUP Connect™ or contact ARUP Client Services at (800) 522-2787. (Min: 1 g)

Unacceptable Conditions

Specimens in media or preservatives.

Storage/Transport Temperature

Refrigerated.

Stability (from collection to initiation)

Ambient: 11 days; Refrigerated: 11 days; Frozen: 1 year

Notes

Fecal Calprotectin is an indicator of the presence of neutrophils in stool and is not specific for IBD. Other intestinal ailments including GI infections and colorectal cancer can result in elevated concentrations of calprotectin. The diagnosis of IBD cannot be established solely on the basis of a positive calprotectin result. Patients with IBD fluctuate between active and inactive stages of disease. Calprotectin results may also fluctuate. GI bleeding of as much as 100 mL per day will increase the fecal calprotectin concentration by only 15 µg/g.
Ordering

Performed

Sun-Sat

Methodology

Quantitative Enzyme-Linked Immunosorbent Assay

Reported

1-3 days

Synonyms

  • LAB3763
  • CALPRO

Additional Technical Information

Ordering Recommendations

Aid in differentiation of inflammatory bowel disease (IBD) from irritable bowel syndrome (IBS) and other functional disorders of the gastrointestinal (GI) system. Aid in monitoring IBD and prediction of relapse.
Result Interpretation

Reference Interval

Effective August 15, 2016
50 µg/g or less: Normal
51-120 µg/g: Borderline elevated, test should be re-evaluated in 4-6 weeks.
121 µg/g or greater: Abnormal
Administrative

CPT Codes

83993

CALRETICULIN GENE MUTATIONS

LAB5190

Collect

5.0 mL EDTA whole blood (purple or pink top tubes) Minimum volume = 3 mL

or 1-2 mL Bone Marrow (in EDTA)

Unacceptable Conditions

Serum or plasma.

Storage/Transport Temperature

Refrigerate until shipped.

Remarks

Testing performed for the entire coding region of CALR exon 9.

Performed by

Performed by CHILDREN'S HOSPITAL COLORADO

DEPARTMENT OF PATHOLOGY in AURORA, CO.

Performed

Weekly.

Methodology

PCR and bi-directional sequencing of the CALR exon 9 and fragment analysis to detect low level insertion/deletion.

Reported

5-7 days

Reference Interval

No CALR mutations detected.

Performed by

Performed by CHILDREN'S HOSPITAL COLORADO

DEPARTMENT OF PATHOLOGY in AURORA, CO.

Collection

LAB5190

Collect

5.0 mL EDTA whole blood (purple or pink top tubes) Minimum volume = 3 mL

or 1-2 mL Bone Marrow (in EDTA)

Unacceptable Conditions

Serum or plasma.

Storage/Transport Temperature

Refrigerate until shipped.

Remarks

Testing performed for the entire coding region of CALR exon 9.

Performed by

Performed by CHILDREN'S HOSPITAL COLORADO

DEPARTMENT OF PATHOLOGY in AURORA, CO.

Ordering

Performed

Weekly.

Methodology

PCR and bi-directional sequencing of the CALR exon 9 and fragment analysis to detect low level insertion/deletion.

Reported

5-7 days

Result Interpretation

Reference Interval

No CALR mutations detected.

Performed by

Performed by CHILDREN'S HOSPITAL COLORADO

DEPARTMENT OF PATHOLOGY in AURORA, CO.

Administrative

CANCER ANTIGEN 125

LAB155

CA125

Collect

One 5.0 mL gold or red top with gel (SST), (clot activator serum)

Unacceptable Conditions

Specimen not properly labeled; incoorrect container; insufficient sample volume.

Storage/Transport Temperature

Internal: Deliver to lab immediately.
Offsite: Let sample clot for 30 minutes before spinning. Spin sample and send tube to main lab refrigerated.

Note: if sample delivery will exceed 48 hours, aliquot 1ml into a plastic tube and freeze for transport.

Stability (from collection to initiation)

Ambient temperature: 8 hours; Refrigerated: 48 hours.

Performed by

PCL Clinical Laboratory - Core

Performed

Daily

Methodology

Chemilumenescent EIA

Reported

Daily

Synonyms

  • LAB155

Reference Interval

0-35 U/mL

Performed by

PCL Clinical Laboratory - Core

CPT Codes

86304

Collection

LAB155

CA125

Collect

One 5.0 mL gold or red top with gel (SST), (clot activator serum)

Unacceptable Conditions

Specimen not properly labeled; incoorrect container; insufficient sample volume.

Storage/Transport Temperature

Internal: Deliver to lab immediately.
Offsite: Let sample clot for 30 minutes before spinning. Spin sample and send tube to main lab refrigerated.

Note: if sample delivery will exceed 48 hours, aliquot 1ml into a plastic tube and freeze for transport.

Stability (from collection to initiation)

Ambient temperature: 8 hours; Refrigerated: 48 hours.

Performed by

PCL Clinical Laboratory - Core

Ordering

Performed

Daily

Methodology

Chemilumenescent EIA

Reported

Daily

Synonyms

  • LAB155
Result Interpretation

Reference Interval

0-35 U/mL

Performed by

PCL Clinical Laboratory - Core

Administrative

CPT Codes

86304

CANCER ANTIGEN 15-3(CA-BREAST)

LAB776

Collect

Serum separator tube or plasma separator tube. Also acceptable: Green (sodium or lithium heparin), lavender (EDTA), or pink (K2EDTA).

Specimen Preparation

Allow specimen to clot completely at room temperature. Separate serum or plasma from cells ASAP or within 2 hours of collection. Transfer 1 mL serum or plasma to an ARUP Standard Transport Tube. (Min: 0.5 mL)

Storage/Transport Temperature

Refrigerated.

Stability (from collection to initiation)

After separation from cells: Ambient: 48 hours; Refrigerated: 5 days; Frozen: 3 months

Performed

Sun-Sat

Methodology

Quantitative Electrochemiluminescent Immunoassay

Reported

Within 24 hours

Synonyms

  • CA-Breast (CA 15-3)
  • CA 15-3
  • LAB776

Ordering Recommendations

Monitor therapy and identify disease recurrence in individuals with metastatic breast cancer. Do not use for diagnosis or screening of breast cancer.

Reference Interval

0-31 U/mL

Interpretive Data

The Roche CA 15-3 electrochemiluminescent immunoassay is used. Results obtained with different methods or kits cannot be used interchangeably. The CA 15-3 test is used to aid in the management of Stage II and III breast cancer patients. Serial testing for patient CA 15-3 values should be used in conjunction with other clinical methods for monitoring breast cancer. Patients with confirmed breast carcinoma frequently have CA 15-3 values in the same range as healthy individuals. Elevations may be observed in patients with nonmalignant disease. Therefore, a CA 15-3 value, regardless of level, should not be interpreted as absolute evidence of the presence or absence of malignant disease.

CPT Codes

86300
Collection

LAB776

Collect

Serum separator tube or plasma separator tube. Also acceptable: Green (sodium or lithium heparin), lavender (EDTA), or pink (K2EDTA).

Specimen Preparation

Allow specimen to clot completely at room temperature. Separate serum or plasma from cells ASAP or within 2 hours of collection. Transfer 1 mL serum or plasma to an ARUP Standard Transport Tube. (Min: 0.5 mL)

Storage/Transport Temperature

Refrigerated.

Stability (from collection to initiation)

After separation from cells: Ambient: 48 hours; Refrigerated: 5 days; Frozen: 3 months
Ordering

Performed

Sun-Sat

Methodology

Quantitative Electrochemiluminescent Immunoassay

Reported

Within 24 hours

Synonyms

  • CA-Breast (CA 15-3)
  • CA 15-3
  • LAB776

Ordering Recommendations

Monitor therapy and identify disease recurrence in individuals with metastatic breast cancer. Do not use for diagnosis or screening of breast cancer.
Result Interpretation

Reference Interval

0-31 U/mL

Interpretive Data

The Roche CA 15-3 electrochemiluminescent immunoassay is used. Results obtained with different methods or kits cannot be used interchangeably. The CA 15-3 test is used to aid in the management of Stage II and III breast cancer patients. Serial testing for patient CA 15-3 values should be used in conjunction with other clinical methods for monitoring breast cancer. Patients with confirmed breast carcinoma frequently have CA 15-3 values in the same range as healthy individuals. Elevations may be observed in patients with nonmalignant disease. Therefore, a CA 15-3 value, regardless of level, should not be interpreted as absolute evidence of the presence or absence of malignant disease.

Administrative

CPT Codes

86300

CANCER ANTIGEN 19-9 (CA-GI)

LAB777

CA199

Collect

One Green top tube with gel separator.

Also acceptable: Any Red top with or without a gel separator. Green top tube without gel separator.

Pediatric Collection

Minimum volume: 1.5 mL blood.

Unacceptable Conditions

Sample not properly identified; Incorrect container; Insufficient sample volume.

Storage/Transport Temperature

Internal: Deliver to lab immediately.
Offsite: Centrifuge and transport refrigerated.

Stability (from collection to initiation)

Plasma/Serum is stable at ambient temperature for 8 hours; refrigerated 48 hours; frozen 3 months.

Performed by

PCL Clinical Laboratory - Core

Performed

Daily

Methodology

Beckman DxI Chemiluminescence

Reported

Daily

Synonyms

  • LAB777

Reference Interval

0.0-35.0 U/mL

Interpretive Data

Patients must possess the ability to express the Lewis blood group antigen or they will be unable to produce the CA 19-9 antigen even in the presence of proven malignancy. A patient with a positive genotype for the Lewis antigen may produce varying levels of CA 19-9 antigen. Phenotyping for the presence of the Lewis blood group antigen may be insufficient to detect true Lewis antigen negative individuals.

Performed by

PCL Clinical Laboratory - Core

CPT Codes

86301

Collection

LAB777

CA199

Collect

One Green top tube with gel separator.

Also acceptable: Any Red top with or without a gel separator. Green top tube without gel separator.

Pediatric Collection

Minimum volume: 1.5 mL blood.

Unacceptable Conditions

Sample not properly identified; Incorrect container; Insufficient sample volume.

Storage/Transport Temperature

Internal: Deliver to lab immediately.
Offsite: Centrifuge and transport refrigerated.

Stability (from collection to initiation)

Plasma/Serum is stable at ambient temperature for 8 hours; refrigerated 48 hours; frozen 3 months.

Performed by

PCL Clinical Laboratory - Core

Ordering

Performed

Daily

Methodology

Beckman DxI Chemiluminescence

Reported

Daily

Synonyms

  • LAB777
Result Interpretation

Reference Interval

0.0-35.0 U/mL

Interpretive Data

Patients must possess the ability to express the Lewis blood group antigen or they will be unable to produce the CA 19-9 antigen even in the presence of proven malignancy. A patient with a positive genotype for the Lewis antigen may produce varying levels of CA 19-9 antigen. Phenotyping for the presence of the Lewis blood group antigen may be insufficient to detect true Lewis antigen negative individuals.

Performed by

PCL Clinical Laboratory - Core

Administrative

CPT Codes

86301

CANCER ANTIGEN 27.29

LAB853

CA2729

Collect

One Gold top tube with gel separator (SST).

Also acceptable: Red top tube without gel separator.

Pediatric Collection

Minimum volume: 3 mL blood

Unacceptable Conditions

Sample not properly identified; Incorrect container; insufficient sample volume.

Storage/Transport Temperature

Internal: Deliver to lab immediately.
Offsite: Centrifuge and transport refrigerated to laboratory.

Stability (from collection to initiation)

Ambient temperature: 8 hours; Refrigerated: 2 days.

Performed by

PCL Clinical Laboratory - Core

Performed

Upon receipt

Methodology

Chemilumenescent Immunoassay

Reported

Same day

Synonyms

  • LAB853

Reference Interval

0-40 U/mL

Performed by

PCL Clinical Laboratory - Core

CPT Codes

86300

Collection

LAB853

CA2729

Collect

One Gold top tube with gel separator (SST).

Also acceptable: Red top tube without gel separator.

Pediatric Collection

Minimum volume: 3 mL blood

Unacceptable Conditions

Sample not properly identified; Incorrect container; insufficient sample volume.

Storage/Transport Temperature

Internal: Deliver to lab immediately.
Offsite: Centrifuge and transport refrigerated to laboratory.

Stability (from collection to initiation)

Ambient temperature: 8 hours; Refrigerated: 2 days.

Performed by

PCL Clinical Laboratory - Core

Ordering

Performed

Upon receipt

Methodology

Chemilumenescent Immunoassay

Reported

Same day

Synonyms

  • LAB853
Result Interpretation

Reference Interval

0-40 U/mL

Performed by

PCL Clinical Laboratory - Core

Administrative

CPT Codes

86300

CANCER-ASSOCIATED RETINOPATHY ANTIBODIES

LAB3125

Collect

One 7 mL red top with gel. [Min vol: 5 mL].

Unacceptable Conditions

Frozen specimens

Storage/Transport Temperature

Internal: Deliver to lab immediatley
Offsite: 2 mL serum Separate serum from cells and refrigerate.

Stability (from collection to initiation)

Refrigerated: 14 days.

Ambient: 72 hours.

Performed by

Athena Diagnostics

Performed

Mon, Wed, Fri

Methodology

Western Blot. Detection of anti-CAR antibodies using recombinant human antigens.

Reported

7 - 14 days

Synonyms

  • CAR ANTIBODIES
  • ANTI-RETINAL ANTIBODIES
  • LAB3125

Performed by

Athena Diagnostics

CPT Codes

84182

Collection

LAB3125

Collect

One 7 mL red top with gel. [Min vol: 5 mL].

Unacceptable Conditions

Frozen specimens

Storage/Transport Temperature

Internal: Deliver to lab immediatley
Offsite: 2 mL serum Separate serum from cells and refrigerate.

Stability (from collection to initiation)

Refrigerated: 14 days.

Ambient: 72 hours.

Performed by

Athena Diagnostics

Ordering

Performed

Mon, Wed, Fri

Methodology

Western Blot. Detection of anti-CAR antibodies using recombinant human antigens.

Reported

7 - 14 days

Synonyms

  • CAR ANTIBODIES
  • ANTI-RETINAL ANTIBODIES
  • LAB3125
Result Interpretation

Performed by

Athena Diagnostics

Administrative

CPT Codes

84182

CANDIDA ANTIBODY [ID]

LAB1207

Collect

Serum separator tube.

Specimen Preparation

Separate serum from cells ASAP or within 2 hours of collection. Transfer 0.5 mL serum to an ARUP Standard Transport Tube. (Min: 0.15 mL)

Unacceptable Conditions

Body fluids.

Storage/Transport Temperature

Refrigerated.

Stability (from collection to initiation)

After separation from cells: Ambient: 48 hours; Refrigerated: 2 weeks; Frozen: 1 year (avoid repeated freeze/thaw cycles)

Performed

Sun-Sat

Methodology

Qualitative Immunodiffusion

Reported

2-4 days

Synonyms

  • LAB1207
  • CAN PPT

Ordering Recommendations

Limited clinical utility.

Reference Interval

None detected.

Interpretive Data

Serum from healthy individuals and patients with mucocutaneous candidiasis generally does not have positive immunodiffusion tests. Approximately 88% of immunologically competent patients with visceral candidiasis will demonstrate one or more precipitin bands. Two to nine bands have been associated with serum from patients with systemic infections. Generally, the greater the number of bands, the more severe the infection (except with immunocompromised patients).

CPT Codes

86628
Collection

LAB1207

Collect

Serum separator tube.

Specimen Preparation

Separate serum from cells ASAP or within 2 hours of collection. Transfer 0.5 mL serum to an ARUP Standard Transport Tube. (Min: 0.15 mL)

Unacceptable Conditions

Body fluids.

Storage/Transport Temperature

Refrigerated.

Stability (from collection to initiation)

After separation from cells: Ambient: 48 hours; Refrigerated: 2 weeks; Frozen: 1 year (avoid repeated freeze/thaw cycles)
Ordering

Performed

Sun-Sat

Methodology

Qualitative Immunodiffusion

Reported

2-4 days

Synonyms

  • LAB1207
  • CAN PPT

Ordering Recommendations

Limited clinical utility.
Result Interpretation

Reference Interval

None detected.

Interpretive Data

Serum from healthy individuals and patients with mucocutaneous candidiasis generally does not have positive immunodiffusion tests. Approximately 88% of immunologically competent patients with visceral candidiasis will demonstrate one or more precipitin bands. Two to nine bands have been associated with serum from patients with systemic infections. Generally, the greater the number of bands, the more severe the infection (except with immunocompromised patients).

Administrative

CPT Codes

86628

CAPILLARY BLOOD GAS

LAB78

CAPBG

Collect

At least 0.110 mL capillary whole blood in plastic capillary collection tube with balanced heparin anticoagulant. Insert mixing flea prior to collection. Mix well with flea/magnet to decrease risk of clotting. Avoid air bubbles during collection or mixing steps.

Pediatric Collection

0.70 mL capillary whole blood collected in plastic capillary collection tube with balanced heparin.

Unacceptable Conditions

Samples containing EDTA or Citrate; air bubbles in sample; clotted sample; sample not properly identified; insufficient sample volume.

Storage/Transport Temperature

Internal: Deliver to the laboratory immediately. Maintain sample at ambient temperature. Deliver to the laboratory within 30 minutes of collection. If sample cannot be submitted to the laboratory within 30 minutes, transport on cold pack.

Offsite: Utilize emergency courier to provide for transport criteria listed above.

Stability (from collection to initiation)

Ambient: 30 minutes; On Ice: 1 hour

Remarks

Use of dry balanced heparin improves electrolyte and pH accuracy. Immediately remove any air bubbles from collected sample prior to transport.

Performed by

PCL Clinical Laboratory - Core

Performed

Upon Receipt

Methodology

Ion Selective Electrode

Reported

Within 1 hour of receipt.

Reference Interval

pH

7.35-7.45

pCO2

35-40 mmHg

pO2

65-75 mmHg

HCO3

18-23 mmol/L

TCO2

19-24 mmol/L

Base Excess

-2 -+3 mmol/L

O2 Sat

95-100%

Performed by

PCL Clinical Laboratory - Core

CPT Codes

82805

Collection

LAB78

CAPBG

Collect

At least 0.110 mL capillary whole blood in plastic capillary collection tube with balanced heparin anticoagulant. Insert mixing flea prior to collection. Mix well with flea/magnet to decrease risk of clotting. Avoid air bubbles during collection or mixing steps.

Pediatric Collection

0.70 mL capillary whole blood collected in plastic capillary collection tube with balanced heparin.

Unacceptable Conditions

Samples containing EDTA or Citrate; air bubbles in sample; clotted sample; sample not properly identified; insufficient sample volume.

Storage/Transport Temperature

Internal: Deliver to the laboratory immediately. Maintain sample at ambient temperature. Deliver to the laboratory within 30 minutes of collection. If sample cannot be submitted to the laboratory within 30 minutes, transport on cold pack.

Offsite: Utilize emergency courier to provide for transport criteria listed above.

Stability (from collection to initiation)

Ambient: 30 minutes; On Ice: 1 hour

Remarks

Use of dry balanced heparin improves electrolyte and pH accuracy. Immediately remove any air bubbles from collected sample prior to transport.

Performed by

PCL Clinical Laboratory - Core

Ordering

Performed

Upon Receipt

Methodology

Ion Selective Electrode

Reported

Within 1 hour of receipt.

Result Interpretation

Reference Interval

pH

7.35-7.45

pCO2

35-40 mmHg

pO2

65-75 mmHg

HCO3

18-23 mmol/L

TCO2

19-24 mmol/L

Base Excess

-2 -+3 mmol/L

O2 Sat

95-100%

Performed by

PCL Clinical Laboratory - Core

Administrative

CPT Codes

82805

CARBAMAZEPINE

LAB21

CARBAM

 

Collect

One 4.5 mL, green top with gel (PST), (lithium heparin plasma)

Unacceptable Conditions

Sample not properly identified; incorrect container; insufficient sample volume.

Storage/Transport Temperature

Internal: Deliver to lab immediately.
Offsite: Centrifuge and separate plasma from cells. Send at 2-8 degrees C. If not analyzed within 24 hours, freeze sample at -20 degrees C.

Stability (from collection to initiation)

Stable for 24 hours at 2-8 degrees C. Freeze plasma at -20 degrees C if not analyzed within 24 hours.

Remarks

Trough levels should be drawn immediately before the next dose. If toxicity is suspected, draw at any time.

Performed by

PCL Clinical Laboratory - Core

Performed

Daily

Methodology

Immuno-Turbidimetry

Reported

Same day

Synonyms

  • Tegretol Level
  • LAB21

Reference Interval

4.0-12.0 ug/mL

Interpretive Data

Therapeutic carbamazepine concentrations vary among individuals. The reference interval displayed for this test was taken from published literature. Interpretations of this result must be made in the context of the individual's clinical scenario.

Performed by

PCL Clinical Laboratory - Core

CPT Codes

80156

Collection

LAB21

CARBAM

 

Collect

One 4.5 mL, green top with gel (PST), (lithium heparin plasma)

Unacceptable Conditions

Sample not properly identified; incorrect container; insufficient sample volume.

Storage/Transport Temperature

Internal: Deliver to lab immediately.
Offsite: Centrifuge and separate plasma from cells. Send at 2-8 degrees C. If not analyzed within 24 hours, freeze sample at -20 degrees C.

Stability (from collection to initiation)

Stable for 24 hours at 2-8 degrees C. Freeze plasma at -20 degrees C if not analyzed within 24 hours.

Remarks

Trough levels should be drawn immediately before the next dose. If toxicity is suspected, draw at any time.

Performed by

PCL Clinical Laboratory - Core

Ordering

Performed

Daily

Methodology

Immuno-Turbidimetry

Reported

Same day

Synonyms

  • Tegretol Level
  • LAB21
Result Interpretation

Reference Interval

4.0-12.0 ug/mL

Interpretive Data

Therapeutic carbamazepine concentrations vary among individuals. The reference interval displayed for this test was taken from published literature. Interpretations of this result must be made in the context of the individual's clinical scenario.

Performed by

PCL Clinical Laboratory - Core

Administrative

CPT Codes

80156

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