Tests Catalogs

CHLAMYDIA PNEUMONIAE PCR

LAB3242
CHLPPCR

Collect

Whole blood, serum, or plasma: One 6.0 mL pink top or one 4.0 mL purple top (EDTA).
All other sample types: Submit in a sterile container.
Specimen source must be identified on order or requisition.

Pediatric Collection

0.5 mL

Unacceptable Conditions

Specimen not properly identified; incorrect container; insufficient sample volume.

Storage/Transport Temperature

Internal: Deliver to lab immediately.
Offsite: Send at 2-8 degrees C if delivery is less than 24 hours. If delivery is not expected within 24 hours, freeze at -70 degrees C and ship on dry ice. For plasma and serum, centrifuge and transfer supernatant to an aliquot tube before freezing.

Stability (from collection to initiation)

Ambient: 12 hours, Refrigerated: 72 hours, Frozen (-70 degrees C): 6 months

Performed by

PCL Clinical Laboratory - Molecular Diagnostics

Performed

2 times per week

Methodology

DNA amplification by polymerase chain reaction (PCR) with gel-electrophoresis of PCR products.

Reported

Varies

Synonyms

  • LAB3242
  • CHLPPCR

Interpretive Data

Not Detected (negative)

Detected (positive)

Performed by

PCL Clinical Laboratory - Molecular Diagnostics

CPT Codes

87486

Collection

LAB3242
CHLPPCR

Collect

Whole blood, serum, or plasma: One 6.0 mL pink top or one 4.0 mL purple top (EDTA).
All other sample types: Submit in a sterile container.
Specimen source must be identified on order or requisition.

Pediatric Collection

0.5 mL

Unacceptable Conditions

Specimen not properly identified; incorrect container; insufficient sample volume.

Storage/Transport Temperature

Internal: Deliver to lab immediately.
Offsite: Send at 2-8 degrees C if delivery is less than 24 hours. If delivery is not expected within 24 hours, freeze at -70 degrees C and ship on dry ice. For plasma and serum, centrifuge and transfer supernatant to an aliquot tube before freezing.

Stability (from collection to initiation)

Ambient: 12 hours, Refrigerated: 72 hours, Frozen (-70 degrees C): 6 months

Performed by

PCL Clinical Laboratory - Molecular Diagnostics

Ordering

Performed

2 times per week

Methodology

DNA amplification by polymerase chain reaction (PCR) with gel-electrophoresis of PCR products.

Reported

Varies

Synonyms

  • LAB3242
  • CHLPPCR
Result Interpretation

Interpretive Data

Not Detected (negative)

Detected (positive)

Performed by

PCL Clinical Laboratory - Molecular Diagnostics

Administrative

CPT Codes

87486

CHLAMYDIA/GC GENPROBE

LAB4739

Collect

Female endocervical swab, male urethral swab, throat swab, rectal swab, or eye swab; submit only small (blue) collection swab in Gen-Probe Aptima Combo 2 swab specimen transport tubes.

 

2 mL sample of first catch urine added to Gen-Probe Aptima Combo 2 urine specimen transport container.

Samples should be transferred into Gen-Probe Aptima Combo 2 specimen transport tubes within 24 hours of collection.

Unacceptable Conditions

Swabs not submitted in Gen-Probe Aptima Combo 2 transport tubes.

Urine samples not sent in Gen-Probe Aptima Combo 2 urine specimen transport container.

More than or less than 2 mL of urine added to Gen-Probe Aptima Combo 2 urine specimen transport container.

 

Storage/Transport Temperature

Internal: Deliver to lab immediately at ambient temperature.

Offsite: Deliver to lab at ambient temperature.

Stability (from collection to initiation)

After transfer into Gen-Probe Aptima Combo 2 transport tubes:

Swabs: Ambient, 60 days. Urine: Ambient, 30 days.

Remarks

Both Chlamydia Trachomatis and Neisseria Gonorrhoeae Amplified Probe testing performed.

Performed by

PCL Clinical Laboratory - Molecular Diagnostics

Performed

Mon - Fri

Methodology

Gen-Probe Aptima Combo 2 Assay

Reported

Same day, next run if repeat testing is necessary

Performed by

PCL Clinical Laboratory - Molecular Diagnostics

CPT Codes

87491; 87591

Collection

LAB4739

Collect

Female endocervical swab, male urethral swab, throat swab, rectal swab, or eye swab; submit only small (blue) collection swab in Gen-Probe Aptima Combo 2 swab specimen transport tubes.

 

2 mL sample of first catch urine added to Gen-Probe Aptima Combo 2 urine specimen transport container.

Samples should be transferred into Gen-Probe Aptima Combo 2 specimen transport tubes within 24 hours of collection.

Unacceptable Conditions

Swabs not submitted in Gen-Probe Aptima Combo 2 transport tubes.

Urine samples not sent in Gen-Probe Aptima Combo 2 urine specimen transport container.

More than or less than 2 mL of urine added to Gen-Probe Aptima Combo 2 urine specimen transport container.

 

Storage/Transport Temperature

Internal: Deliver to lab immediately at ambient temperature.

Offsite: Deliver to lab at ambient temperature.

Stability (from collection to initiation)

After transfer into Gen-Probe Aptima Combo 2 transport tubes:

Swabs: Ambient, 60 days. Urine: Ambient, 30 days.

Remarks

Both Chlamydia Trachomatis and Neisseria Gonorrhoeae Amplified Probe testing performed.

Performed by

PCL Clinical Laboratory - Molecular Diagnostics

Ordering

Performed

Mon - Fri

Methodology

Gen-Probe Aptima Combo 2 Assay

Reported

Same day, next run if repeat testing is necessary

Result Interpretation

Performed by

PCL Clinical Laboratory - Molecular Diagnostics

Administrative

CPT Codes

87491; 87591

CHLORIDE RANDOM URINE

LAB374

CL RANU

Collect

5 mL random urine in plastic container, no preservative.

Minimum volume: 0.2 mL urine

Unacceptable Conditions

Sample not properly identified; incorrect container; insufficient sample volume.

Storage/Transport Temperature

Internal: Deliver to lab immediately.
Offsite: Transport to lab at ambient temperature.

Stability (from collection to initiation)

Ambient: indefinitely; Refrigerated: indefinitely; Frozen: indefinitely.

Performed by

PCL Clinical Laboratory - Core

Performed

Daily

Methodology

Indirect ISE

Reported

Same day

Reference Interval

Reference interval for random urine has not been established.

Interpretive Data

Effective 05/20/2014:

Reference ranges are available for 24-hour urine specimens.

Performed by

PCL Clinical Laboratory - Core

CPT Codes

82436

Collection

LAB374

CL RANU

Collect

5 mL random urine in plastic container, no preservative.

Minimum volume: 0.2 mL urine

Unacceptable Conditions

Sample not properly identified; incorrect container; insufficient sample volume.

Storage/Transport Temperature

Internal: Deliver to lab immediately.
Offsite: Transport to lab at ambient temperature.

Stability (from collection to initiation)

Ambient: indefinitely; Refrigerated: indefinitely; Frozen: indefinitely.

Performed by

PCL Clinical Laboratory - Core

Ordering

Performed

Daily

Methodology

Indirect ISE

Reported

Same day

Result Interpretation

Reference Interval

Reference interval for random urine has not been established.

Interpretive Data

Effective 05/20/2014:

Reference ranges are available for 24-hour urine specimens.

Performed by

PCL Clinical Laboratory - Core

Administrative

CPT Codes

82436

CHLORIDE SERUM/PLASMA

LAB59

CL

Collect

One 4.5 mL green top with gel (PST), (lithium heparin plasma).

Pediatric Collection

At least 0.5 mL blood in a microtainer, green top with gel, plasma (lithium heparin).

Unacceptable Conditions

EDTA or citrate anticoagulant; grossly hemolyzed sample; sample not properly identified; insufficient sample volume.

Storage/Transport Temperature

Internal: Deliver to lab immediately.
Offsite: Centrifuge within 30 minutes of collection. Transport to laboratory at ambient temperature.

Stability (from collection to initiation)

Before centrifugation: 1 hour

After centrifugation: Ambient, 7 days; Refrigerated, 2 days

Plasma aliquot: Ambient , 7 days; Refrigerated, 2 days; Frozen (-20 degrees C), Indefinitely

Performed by

PCL Clinical Laboratory - Core

Performed

Upon receipt

Methodology

Indirect ISE

Reported

Same day

Synonyms

  • LAB59
  • CL

Reference Interval

Effective 05/20/2014:

98 - 108 mmol/L

 

Before 05/20/2014:

Sex From Age To Age Normal Low Normal High Units
M/F 0 16 97 108 mmol/L
M/F 16 150 101 111 mmol/L

Performed by

PCL Clinical Laboratory - Core

CPT Codes

82435

Collection

LAB59

CL

Collect

One 4.5 mL green top with gel (PST), (lithium heparin plasma).

Pediatric Collection

At least 0.5 mL blood in a microtainer, green top with gel, plasma (lithium heparin).

Unacceptable Conditions

EDTA or citrate anticoagulant; grossly hemolyzed sample; sample not properly identified; insufficient sample volume.

Storage/Transport Temperature

Internal: Deliver to lab immediately.
Offsite: Centrifuge within 30 minutes of collection. Transport to laboratory at ambient temperature.

Stability (from collection to initiation)

Before centrifugation: 1 hour

After centrifugation: Ambient, 7 days; Refrigerated, 2 days

Plasma aliquot: Ambient , 7 days; Refrigerated, 2 days; Frozen (-20 degrees C), Indefinitely

Performed by

PCL Clinical Laboratory - Core

Ordering

Performed

Upon receipt

Methodology

Indirect ISE

Reported

Same day

Synonyms

  • LAB59
  • CL
Result Interpretation

Reference Interval

Effective 05/20/2014:

98 - 108 mmol/L

 

Before 05/20/2014:

Sex From Age To Age Normal Low Normal High Units
M/F 0 16 97 108 mmol/L
M/F 16 150 101 111 mmol/L

Performed by

PCL Clinical Laboratory - Core

Administrative

CPT Codes

82435

CHLORIDE TIMED URINE

LAB375

CL TIMU

Collect

Timed urine collection in plastic container.
Mandatory collection information: Start date and time and End date and time of collection.

Pediatric Collection

Timed urine collection in plastic container. Minimum volume 0.2 mL urine.
Mandatory collection information: Start date and time and End date and time of collection.
 

Unacceptable Conditions

Sample not properly identified; incorrect container; insufficient sample volume.

Storage/Transport Temperature

Internal: Deliver to lab immediately.
Offsite: Transport to lab at ambient temperature.

Stability (from collection to initiation)

Ambient: indefinitely; Refrigerated: indefinitely; Frozen:  indefinitely.

.

Remarks

Requisition must state date and collection period (start time and stop time). Indicate total collection volume if submitting an aliquot. Refrigerate during collection.

Performed by

PCL Clinical Laboratory - Core

Performed

Daily

Methodology

Indirect ISE

Reported

Same day

Synonyms

  • LAB375

Reference Interval

110-250 mmol/D

Performed by

PCL Clinical Laboratory - Core

CPT Codes

82436

Collection

LAB375

CL TIMU

Collect

Timed urine collection in plastic container.
Mandatory collection information: Start date and time and End date and time of collection.

Pediatric Collection

Timed urine collection in plastic container. Minimum volume 0.2 mL urine.
Mandatory collection information: Start date and time and End date and time of collection.
 

Unacceptable Conditions

Sample not properly identified; incorrect container; insufficient sample volume.

Storage/Transport Temperature

Internal: Deliver to lab immediately.
Offsite: Transport to lab at ambient temperature.

Stability (from collection to initiation)

Ambient: indefinitely; Refrigerated: indefinitely; Frozen:  indefinitely.

.

Remarks

Requisition must state date and collection period (start time and stop time). Indicate total collection volume if submitting an aliquot. Refrigerate during collection.

Performed by

PCL Clinical Laboratory - Core

Ordering

Performed

Daily

Methodology

Indirect ISE

Reported

Same day

Synonyms

  • LAB375
Result Interpretation

Reference Interval

110-250 mmol/D

Performed by

PCL Clinical Laboratory - Core

Administrative

CPT Codes

82436

CHLORIDE WHOLE BLOOD

LAB3026

CL WB

Collect

Plastic arterial blood gas syringe with dry balanced heparin anticoagulant; or sodium or lithium heparin vacutainer, no gel, filled to at least 75% capacity.

Unacceptable Conditions

Sample not properly identified; incorrect container; insufficient sample volume; sample submitted with needle attached (remove immediately post collection); Air bubbles in sample; clotted sample.

 

 

Storage/Transport Temperature

Internal: Deliver to laboratory immediately.

Offsite: Maintain sample at ambient temperature during transport to laboratory.

Stability (from collection to initiation)

30 minutes at room temperature (Preferred). 1 hour on Ice (Alternate)

Performed by

PCL Clinical Laboratory - Core

Performed

Upon receipt

Methodology

Ion Selective Electrode

Reported

Within 1 hour of receipt

Synonyms

  • LAB3026

Reference Interval

102-111 nmol/L

Performed by

PCL Clinical Laboratory - Core

CPT Codes

82435

Collection

LAB3026

CL WB

Collect

Plastic arterial blood gas syringe with dry balanced heparin anticoagulant; or sodium or lithium heparin vacutainer, no gel, filled to at least 75% capacity.

Unacceptable Conditions

Sample not properly identified; incorrect container; insufficient sample volume; sample submitted with needle attached (remove immediately post collection); Air bubbles in sample; clotted sample.

 

 

Storage/Transport Temperature

Internal: Deliver to laboratory immediately.

Offsite: Maintain sample at ambient temperature during transport to laboratory.

Stability (from collection to initiation)

30 minutes at room temperature (Preferred). 1 hour on Ice (Alternate)

Performed by

PCL Clinical Laboratory - Core

Ordering

Performed

Upon receipt

Methodology

Ion Selective Electrode

Reported

Within 1 hour of receipt

Synonyms

  • LAB3026
Result Interpretation

Reference Interval

102-111 nmol/L

Performed by

PCL Clinical Laboratory - Core

Administrative

CPT Codes

82435

CHLORIDE, 24 HOUR URINE

LAB4844

Collect

Timed urine collection in plastic container.

Mandatory collection information: Start date and time and End date and time of collection.

Pediatric Collection

Timed urine collection in plastic container. Minimum volume 0.2 mL urine.

Mandatory collection information: Start date and time and End date and time of collection.

Unacceptable Conditions

Specimen not properly identified; incorrect container; insufficient sample volume.

Storage/Transport Temperature

Internal: Deliver to lab immediately.

Offsite: Transport to laboratory at ambient temperature.

Stability (from collection to initiation)

Ambient: Indefinitely; Refrigerated: Indefinitely; Frozen: Indefinitely.

Remarks

Requisition must state date and collection period (start time and end time). Indicate total volume when submitting an aliquot. Refrigerate during collection.

Performed by

PCL Clinical Laboratory - Core

Performed

Daily

Methodology

Indirect ISE

Reported

Same day

Reference Interval

110 - 250 mmol/D

Performed by

PCL Clinical Laboratory - Core

CPT Codes

82436

Collection

LAB4844

Collect

Timed urine collection in plastic container.

Mandatory collection information: Start date and time and End date and time of collection.

Pediatric Collection

Timed urine collection in plastic container. Minimum volume 0.2 mL urine.

Mandatory collection information: Start date and time and End date and time of collection.

Unacceptable Conditions

Specimen not properly identified; incorrect container; insufficient sample volume.

Storage/Transport Temperature

Internal: Deliver to lab immediately.

Offsite: Transport to laboratory at ambient temperature.

Stability (from collection to initiation)

Ambient: Indefinitely; Refrigerated: Indefinitely; Frozen: Indefinitely.

Remarks

Requisition must state date and collection period (start time and end time). Indicate total volume when submitting an aliquot. Refrigerate during collection.

Performed by

PCL Clinical Laboratory - Core

Ordering

Performed

Daily

Methodology

Indirect ISE

Reported

Same day

Result Interpretation

Reference Interval

110 - 250 mmol/D

Performed by

PCL Clinical Laboratory - Core

Administrative

CPT Codes

82436

CHOLESTEROL

LAB60

CHOL

 

Collect

One 4.5 mL Green top with gel (PST), plasma (lithium heparin).

Pediatric Collection

At least 0.5 mL whole blood collected in a microtainer, green top with gel, lithium heparin plasma.

Unacceptable Conditions

Gross hemolysis, bilirubinemia, or lipemia; EDTA, citrate, or oxalate anticoagulants; sample not properly identified; incorrect container; insufficient sample volume.

Storage/Transport Temperature

Internal: Deliver to lab immediately at ambient temperature.
Offsite: Centrifuge within 30 minutes of collection. Transport to laboratory at ambient temperature.

Stability (from collection to initiation)

Before centrifugation: Ambient, 1 hour.

After centrifugation: Ambient, 7 days; Refrigerated, 7 days; Frozen, Unacceptable.

Plasma aliquot: Ambient, 7 days; Refrigerated, 7 days, Frozen (-20 degrees C), 3 months.

Remarks

Patient should fast for 9-12 hours prior to blood collection when test is performed as part of a lipid panel.

Performed by

PCL Clinical Laboratory - Core

Performed

Upon receipt

Methodology

Enzymatic

Reported

Same day

Synonyms

  • LAB60
  • CHOL

Reference Interval

Effective 05/20/2014:

136 - 239 mg/dL

 

Before 05/20/2014:

0-200 mg/dL

Interpretive Data

Per NCEP Adult Treatment Panel III suggestions: Less than 200 mg/dL is desirable; 200-239 mg/dL is borderline high; Greater than or equal to 240 mg/dL is high.

Performed by

PCL Clinical Laboratory - Core

CPT Codes

82465

Collection

LAB60

CHOL

 

Collect

One 4.5 mL Green top with gel (PST), plasma (lithium heparin).

Pediatric Collection

At least 0.5 mL whole blood collected in a microtainer, green top with gel, lithium heparin plasma.

Unacceptable Conditions

Gross hemolysis, bilirubinemia, or lipemia; EDTA, citrate, or oxalate anticoagulants; sample not properly identified; incorrect container; insufficient sample volume.

Storage/Transport Temperature

Internal: Deliver to lab immediately at ambient temperature.
Offsite: Centrifuge within 30 minutes of collection. Transport to laboratory at ambient temperature.

Stability (from collection to initiation)

Before centrifugation: Ambient, 1 hour.

After centrifugation: Ambient, 7 days; Refrigerated, 7 days; Frozen, Unacceptable.

Plasma aliquot: Ambient, 7 days; Refrigerated, 7 days, Frozen (-20 degrees C), 3 months.

Remarks

Patient should fast for 9-12 hours prior to blood collection when test is performed as part of a lipid panel.

Performed by

PCL Clinical Laboratory - Core

Ordering

Performed

Upon receipt

Methodology

Enzymatic

Reported

Same day

Synonyms

  • LAB60
  • CHOL
Result Interpretation

Reference Interval

Effective 05/20/2014:

136 - 239 mg/dL

 

Before 05/20/2014:

0-200 mg/dL

Interpretive Data

Per NCEP Adult Treatment Panel III suggestions: Less than 200 mg/dL is desirable; 200-239 mg/dL is borderline high; Greater than or equal to 240 mg/dL is high.

Performed by

PCL Clinical Laboratory - Core

Administrative

CPT Codes

82465

CHOLESTEROL BF

LAB376

CHOL BF

Collect

1 mL fluid in sterile container.

Minimum volume: 0.2 mL fluid.

Unacceptable Conditions

Sample not properly identified; incorrect container; insufficient sample volume.

Storage/Transport Temperature

Internal: Deliver to lab immediately.
Offsite: Transport to lab at ambient temperature.

Stability (from collection to initiation)

Ambient: 7 days; Refrigerated: 7 days; Frozen: 3 months.

Remarks

Identify fluid source on requisition.

Performed by

PCL Clinical Laboratory - Core

Performed

Daily

Methodology

Enzymatic

Reported

Same day

Synonyms

  • LAB376

Interpretive Data

The reference range for cholesterol in body fluids is undefined.  The result must be integrated into the clinical context and/or compared to a synchronous serum or plasma measurement. 
This test was developed and its performance characteristics determined by University of Colorado Hospital.  It has not been cleared or approved by the FDA.  The laboratory is regulated under CLIA as qualified to perform high-complexity testing. This test is used for clinical purposes. It should not be regarded as investigational or for research.

Performed by

PCL Clinical Laboratory - Core

CPT Codes

82465

Collection

LAB376

CHOL BF

Collect

1 mL fluid in sterile container.

Minimum volume: 0.2 mL fluid.

Unacceptable Conditions

Sample not properly identified; incorrect container; insufficient sample volume.

Storage/Transport Temperature

Internal: Deliver to lab immediately.
Offsite: Transport to lab at ambient temperature.

Stability (from collection to initiation)

Ambient: 7 days; Refrigerated: 7 days; Frozen: 3 months.

Remarks

Identify fluid source on requisition.

Performed by

PCL Clinical Laboratory - Core

Ordering

Performed

Daily

Methodology

Enzymatic

Reported

Same day

Synonyms

  • LAB376
Result Interpretation

Interpretive Data

The reference range for cholesterol in body fluids is undefined.  The result must be integrated into the clinical context and/or compared to a synchronous serum or plasma measurement. 
This test was developed and its performance characteristics determined by University of Colorado Hospital.  It has not been cleared or approved by the FDA.  The laboratory is regulated under CLIA as qualified to perform high-complexity testing. This test is used for clinical purposes. It should not be regarded as investigational or for research.

Performed by

PCL Clinical Laboratory - Core

Administrative

CPT Codes

82465

CHROMIUM 24 HOUR URINE

LAB3929

Collect

24-hour or random urine collection. Specimen must be collected in a plastic container. ARUP studies indicate that refrigeration of urine alone, during and after collection, preserves specimens adequately, if tested within 14 days of collection.

Patient Preparation

Diet, medication, and nutritional supplements may introduce interfering substances. Patients should be encouraged to discontinue nutritional supplements, vitamins, minerals, and non-essential over-the-counter medications (upon the advice of their physician). High concentrations of iodine may interfere with elemental testing. Abstinence from iodine-containing medications or contrast agents for at least 1 month prior to collecting specimens for elemental testing is recommended.

Specimen Preparation

Transfer an 8 mL aliquot from a well-mixed collection to ARUP Trace Element-Free Transport Tubes (ARUP supply #43116). Available online through eSupply using ARUP Connect™ or contact ARUP Client Services at (800) 522-2787. (Min: 1 mL)

Unacceptable Conditions

Urine collected within 48 hours after administration of a gadolinium (Gd) containing contrast media (may occur with MRI studies). Acid preserved urine. Specimens contaminated with blood or fecal material. Specimens transported in non-trace element-free transport tube (with the exception of the original device).

Storage/Transport Temperature

Refrigerated. Also acceptable: Room temperature or frozen.

Stability (from collection to initiation)

Ambient: 1 week; Refrigerated: 2 weeks; Frozen: 1 year

Remarks

Record total volume and collection time interval on transport tube and on test request form.

Performed

Tue, Fri

Methodology

Quantitative Inductively Coupled Plasma-Mass Spectrometry

Reported

1-5 days

Synonyms

  • Cr
  • CRU
  • Urine chromium concentration
  • CR U

Additional Technical Information

Ordering Recommendations

Chromium urine levels may be used to monitor short term exposure. Preferred test for evaluating metal ion release from metal-on-metal joint arthroplasty is Chromium, Serum (0098830).

Reference Interval

Components
Reference Interval
Chromium, Urine - per volume0.0-5.0 µg/L
Chromium, Urine - per 24h0.0-6.0 µg/d
Chromium, Urine - ratio to CRTNo reference interval (µg/g crt)
Creatinine, 24-Hour Urine
Age
Male
Female
3-8 years140-700 mg/d140-700 mg/d
9-12 years300-1300 mg/d300-1300 mg/d
13-17 years500-2300 mg/d400-1600 mg/d
18-50 years1000-2500 mg/d700-1600 mg/d
51-80 years800-2100 mg/d500-1400 mg/d
81 years and older600-2000 mg/d400-1300 mg/d


Interpretive Data

Chromium urine levels can be used to monitor short term exposure. The form of chromium greatly influences distribution. Trivalent chromium resides in the plasma and is usually not of clinical importance. Hexavalent chromium is considered highly toxic. Symptoms associated with chromium toxicity vary based upon route of exposure and dose and may include dermatitis, impairment of pulmonary function, gastroenteritis, hepatic necrosis, bleeding, and acute tubular necrosis.

The ACGIH Biological Exposure Index for daily exposure of hexavalent chromium is an increase of 10 µg/gCRT between pre-shift and post-shift urine collections. The ACGIH Biological Exposure Index for long- and short-term hexavalent chromium is an end-of-shift concentration of 30 µg/gCRT at the end of the work week.

CPT Codes

82495
Collection

LAB3929

Collect

24-hour or random urine collection. Specimen must be collected in a plastic container. ARUP studies indicate that refrigeration of urine alone, during and after collection, preserves specimens adequately, if tested within 14 days of collection.

Patient Preparation

Diet, medication, and nutritional supplements may introduce interfering substances. Patients should be encouraged to discontinue nutritional supplements, vitamins, minerals, and non-essential over-the-counter medications (upon the advice of their physician). High concentrations of iodine may interfere with elemental testing. Abstinence from iodine-containing medications or contrast agents for at least 1 month prior to collecting specimens for elemental testing is recommended.

Specimen Preparation

Transfer an 8 mL aliquot from a well-mixed collection to ARUP Trace Element-Free Transport Tubes (ARUP supply #43116). Available online through eSupply using ARUP Connect™ or contact ARUP Client Services at (800) 522-2787. (Min: 1 mL)

Unacceptable Conditions

Urine collected within 48 hours after administration of a gadolinium (Gd) containing contrast media (may occur with MRI studies). Acid preserved urine. Specimens contaminated with blood or fecal material. Specimens transported in non-trace element-free transport tube (with the exception of the original device).

Storage/Transport Temperature

Refrigerated. Also acceptable: Room temperature or frozen.

Stability (from collection to initiation)

Ambient: 1 week; Refrigerated: 2 weeks; Frozen: 1 year

Remarks

Record total volume and collection time interval on transport tube and on test request form.
Ordering

Performed

Tue, Fri

Methodology

Quantitative Inductively Coupled Plasma-Mass Spectrometry

Reported

1-5 days

Synonyms

  • Cr
  • CRU
  • Urine chromium concentration
  • CR U

Additional Technical Information

Ordering Recommendations

Chromium urine levels may be used to monitor short term exposure. Preferred test for evaluating metal ion release from metal-on-metal joint arthroplasty is Chromium, Serum (0098830).
Result Interpretation

Reference Interval

Components
Reference Interval
Chromium, Urine - per volume0.0-5.0 µg/L
Chromium, Urine - per 24h0.0-6.0 µg/d
Chromium, Urine - ratio to CRTNo reference interval (µg/g crt)
Creatinine, 24-Hour Urine
Age
Male
Female
3-8 years140-700 mg/d140-700 mg/d
9-12 years300-1300 mg/d300-1300 mg/d
13-17 years500-2300 mg/d400-1600 mg/d
18-50 years1000-2500 mg/d700-1600 mg/d
51-80 years800-2100 mg/d500-1400 mg/d
81 years and older600-2000 mg/d400-1300 mg/d


Interpretive Data

Chromium urine levels can be used to monitor short term exposure. The form of chromium greatly influences distribution. Trivalent chromium resides in the plasma and is usually not of clinical importance. Hexavalent chromium is considered highly toxic. Symptoms associated with chromium toxicity vary based upon route of exposure and dose and may include dermatitis, impairment of pulmonary function, gastroenteritis, hepatic necrosis, bleeding, and acute tubular necrosis.

The ACGIH Biological Exposure Index for daily exposure of hexavalent chromium is an increase of 10 µg/gCRT between pre-shift and post-shift urine collections. The ACGIH Biological Exposure Index for long- and short-term hexavalent chromium is an end-of-shift concentration of 30 µg/gCRT at the end of the work week.

Administrative

CPT Codes

82495

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