Collect
Serum separator tube or plasma separator tube.
Specimen Preparation
Separate serum or plasma from cells ASAP or within 2 hours of collection. Transfer 1 mL serum or plasma to an ARUP Standard Transport Tube. (Min: 0.1 mL)
Unacceptable Conditions
CSF or other body fluids.
Storage/Transport Temperature
Refrigerated.
Stability (from collection to initiation)
After separation from cells: Ambient: 48 hours; Refrigerated: 2 weeks; Frozen: 1 year (avoid repeated freeze/thaw cycles)
Notes
TP-PA is a helpful diagnostic aid for the patient with a reactive reagin test, but presents with atypical signs of primary, secondary, or late syphilis. TP-PA compares favorably with the FTA test, but appears slightly less sensitive in cases of untreated early primary syphilis. In late syphilis, the agreement with FTA is 99%.
VDRL is the preferred test for cerebrospinal fluid. Treponemal tests (TP-PA or FTA) are not recommended for CSF. FTAs on CSF may be tested, but TP-PA cannot be tested on CSF.
VDRL is the preferred test for cerebrospinal fluid. Treponemal tests (TP-PA or FTA) are not recommended for CSF. FTAs on CSF may be tested, but TP-PA cannot be tested on CSF.
Performed
Mon-Fri
Methodology
Semi-Quantitative Particle Agglutination
Reported
1-4 days
Synonyms
- TP-PA
- T. pallidum Antibody by MHA (MHA-TP)
- MHA-TP
- Syphilis Antibody by MHA
Ordering Recommendations
CDC recommended confirmatory test for syphilis. Order if initial screening (eg, RPR, VDRL) is reactive.
Reference Interval
Nonreactive
CPT Codes
86780
Collection |
Collect
Serum separator tube or plasma separator tube.
Specimen Preparation
Separate serum or plasma from cells ASAP or within 2 hours of collection. Transfer 1 mL serum or plasma to an ARUP Standard Transport Tube. (Min: 0.1 mL)
Unacceptable Conditions
CSF or other body fluids.
Storage/Transport Temperature
Refrigerated.
Stability (from collection to initiation)
After separation from cells: Ambient: 48 hours; Refrigerated: 2 weeks; Frozen: 1 year (avoid repeated freeze/thaw cycles)
Notes
TP-PA is a helpful diagnostic aid for the patient with a reactive reagin test, but presents with atypical signs of primary, secondary, or late syphilis. TP-PA compares favorably with the FTA test, but appears slightly less sensitive in cases of untreated early primary syphilis. In late syphilis, the agreement with FTA is 99%.
VDRL is the preferred test for cerebrospinal fluid. Treponemal tests (TP-PA or FTA) are not recommended for CSF. FTAs on CSF may be tested, but TP-PA cannot be tested on CSF.
VDRL is the preferred test for cerebrospinal fluid. Treponemal tests (TP-PA or FTA) are not recommended for CSF. FTAs on CSF may be tested, but TP-PA cannot be tested on CSF.
Ordering |
Performed
Mon-Fri
Methodology
Semi-Quantitative Particle Agglutination
Reported
1-4 days
Synonyms
- TP-PA
- T. pallidum Antibody by MHA (MHA-TP)
- MHA-TP
- Syphilis Antibody by MHA
Ordering Recommendations
CDC recommended confirmatory test for syphilis. Order if initial screening (eg, RPR, VDRL) is reactive.
Result Interpretation |
Reference Interval
Nonreactive
Administrative |
CPT Codes
86780