Tests Catalogs

TCELL GAMMA/BCELL IG HEAVY BY PCR

LAB3093

Collect

3 mL purple top [EDTA] - whole blood or bone marrow in EDTA; CSF

Unacceptable Conditions

Heparinized samples. Frozen samples.

Storage/Transport Temperature

Internal: Deliver to lab immediatley
Offsite: 1 mL blood/bone marrow/CSF Deliver to lab at ambient temperature.

Stability (from collection to initiation)

3 days ambient.

Remarks

Store blood/bone marrow at ambient temperature until shipment to reference lab. Refrigerate CSF.

Performed by

PCL Clinical Laboratory

Performed

Weekly (Dayshift), day varies

Methodology

Polymerase Chain Reaction (PCR)

Reported

7 - 10 days

Synonyms

  • LAB3093

Performed by

PCL Clinical Laboratory

CPT Codes

81342, 81261

Collection

LAB3093

Collect

3 mL purple top [EDTA] - whole blood or bone marrow in EDTA; CSF

Unacceptable Conditions

Heparinized samples. Frozen samples.

Storage/Transport Temperature

Internal: Deliver to lab immediatley
Offsite: 1 mL blood/bone marrow/CSF Deliver to lab at ambient temperature.

Stability (from collection to initiation)

3 days ambient.

Remarks

Store blood/bone marrow at ambient temperature until shipment to reference lab. Refrigerate CSF.

Performed by

PCL Clinical Laboratory

Ordering

Performed

Weekly (Dayshift), day varies

Methodology

Polymerase Chain Reaction (PCR)

Reported

7 - 10 days

Synonyms

  • LAB3093
Result Interpretation

Performed by

PCL Clinical Laboratory

Administrative

CPT Codes

81342, 81261

T-CELL PANEL

LAB931

TCP

Collect

One 4 or 6 mL dark green top tube (sodium heparin) AND one 4 mL Purple top tube (EDTA).

Dark Green and EDTA must be collected at same draw.

Pediatric Collection

3 mL Green top (sodium heparin) AND 3 mL purple top tube (EDTA) or microtainer (EDTA).

Unacceptable Conditions

Specimen not properly identified; incorrect container; insufficient sample volume; specimen older than 24 hours; clotted, frozen, or hemolyzed specimen.

Storage/Transport Temperature

Internal: Deliver to lab immediately.
Offsite: Transport at ambient temperature.

Stability (from collection to initiation)

Ambient: Green top/purple top tubes for lymphocyte subset analysis 24 hours; Purple top tube for CBC 8 hours.

 

Refrigerated: Purple top tube for CBC 36 hours.

Remarks

T Cell Panel requires an Absolute Lymphocyte Count. A Complete Blood Count (CBC) and differential (DIFF) must be ordered. CPT code 85025 or 85027 and 85007 will be billed as needed.

Performed by

PCL Clinical Laboratory - Flow Cytometry

Performed

Daily

Methodology

Flow Cytometry

Reported

Same day

Synonyms

  • LAB931
  • TCP

Reference Interval

Component Sex From Age To Age Normal Low Normal High Units
CD4:CD8 RATIO M/F 0 150 1.0 3.3 %
HELPER T CELLS: %CD3+CD4+ M/F 3 21 33 44 %
M/F 21 150 32 66 %
HELPER T CELLS: ABS CD3+CD4+ M/F 3 21 1216 2009 /uL
M/F 21 150 389 1868 /uL
SUPPRESSOR T CELL:ABS CD3+CD8+ M/F 3 21 351 2479 /uL
M/F 21 150 185 1049 /uL
SUPPRESSOR T CELLS: %CD3+CD8+ M/F 3 21 8 31 %
M/F 21 150 14 42 %
TOTAL T CELLS: %CD3+ M/F 3 21 55 82 %
M/F 21 150 63 86 %
TOTAL T CELLS: ABS CD3+ M/F 3 21 2649 3639 /uL
M/F 21 150 760 2130 /uL

Performed by

PCL Clinical Laboratory - Flow Cytometry

CPT Codes

86359, 86360

Collection

LAB931

TCP

Collect

One 4 or 6 mL dark green top tube (sodium heparin) AND one 4 mL Purple top tube (EDTA).

Dark Green and EDTA must be collected at same draw.

Pediatric Collection

3 mL Green top (sodium heparin) AND 3 mL purple top tube (EDTA) or microtainer (EDTA).

Unacceptable Conditions

Specimen not properly identified; incorrect container; insufficient sample volume; specimen older than 24 hours; clotted, frozen, or hemolyzed specimen.

Storage/Transport Temperature

Internal: Deliver to lab immediately.
Offsite: Transport at ambient temperature.

Stability (from collection to initiation)

Ambient: Green top/purple top tubes for lymphocyte subset analysis 24 hours; Purple top tube for CBC 8 hours.

 

Refrigerated: Purple top tube for CBC 36 hours.

Remarks

T Cell Panel requires an Absolute Lymphocyte Count. A Complete Blood Count (CBC) and differential (DIFF) must be ordered. CPT code 85025 or 85027 and 85007 will be billed as needed.

Performed by

PCL Clinical Laboratory - Flow Cytometry

Ordering

Performed

Daily

Methodology

Flow Cytometry

Reported

Same day

Synonyms

  • LAB931
  • TCP
Result Interpretation

Reference Interval

Component Sex From Age To Age Normal Low Normal High Units
CD4:CD8 RATIO M/F 0 150 1.0 3.3 %
HELPER T CELLS: %CD3+CD4+ M/F 3 21 33 44 %
M/F 21 150 32 66 %
HELPER T CELLS: ABS CD3+CD4+ M/F 3 21 1216 2009 /uL
M/F 21 150 389 1868 /uL
SUPPRESSOR T CELL:ABS CD3+CD8+ M/F 3 21 351 2479 /uL
M/F 21 150 185 1049 /uL
SUPPRESSOR T CELLS: %CD3+CD8+ M/F 3 21 8 31 %
M/F 21 150 14 42 %
TOTAL T CELLS: %CD3+ M/F 3 21 55 82 %
M/F 21 150 63 86 %
TOTAL T CELLS: ABS CD3+ M/F 3 21 2649 3639 /uL
M/F 21 150 760 2130 /uL

Performed by

PCL Clinical Laboratory - Flow Cytometry

Administrative

CPT Codes

86359, 86360

TESTOSTERONE

LAB124

TESTOS

Collect

One 4.5 mL Gold top tube with gel separator (SST), clot activator serum.

Pediatric Collection

0.5 mL serum

Unacceptable Conditions

Specimen not properly identified; incorrect container; insufficient sample volume; specimens thawed more than twice.

Storage/Transport Temperature

Internal: Deliver to lab immediately.
Offsite: Allow to clot for 30 minutes prior to centrifugation. Centrifuge within 2 hours of collection. Send at 2-8 degrees C if tested within 48 hours. Place serum in aliquot container and send frozen if not tested within 48 hours.

Stability (from collection to initiation)

After centrifugation:

Ambient, 8 hours; Refrigerated, 2 days; Frozen (-20 degrees C), Unacceptable.

Serum aliquot:

Ambient, 8 hours; Refrigerated, 2 days; Frozen (-20 degrees C), Unknown.

Frozen samples may only be thawed one time.

Performed by

PCL Clinical Laboratory - Core

Performed

Daily

Methodology

Chemiluminescence

Reported

Daily

Synonyms

  • LAB124

Reference Interval

Female: 14-76 ng/dL

Male: 241-827 ng/dL 

 

 

Performed by

PCL Clinical Laboratory - Core

CPT Codes

84403

Collection

LAB124

TESTOS

Collect

One 4.5 mL Gold top tube with gel separator (SST), clot activator serum.

Pediatric Collection

0.5 mL serum

Unacceptable Conditions

Specimen not properly identified; incorrect container; insufficient sample volume; specimens thawed more than twice.

Storage/Transport Temperature

Internal: Deliver to lab immediately.
Offsite: Allow to clot for 30 minutes prior to centrifugation. Centrifuge within 2 hours of collection. Send at 2-8 degrees C if tested within 48 hours. Place serum in aliquot container and send frozen if not tested within 48 hours.

Stability (from collection to initiation)

After centrifugation:

Ambient, 8 hours; Refrigerated, 2 days; Frozen (-20 degrees C), Unacceptable.

Serum aliquot:

Ambient, 8 hours; Refrigerated, 2 days; Frozen (-20 degrees C), Unknown.

Frozen samples may only be thawed one time.

Performed by

PCL Clinical Laboratory - Core

Ordering

Performed

Daily

Methodology

Chemiluminescence

Reported

Daily

Synonyms

  • LAB124
Result Interpretation

Reference Interval

Female: 14-76 ng/dL

Male: 241-827 ng/dL 

 

 

Performed by

PCL Clinical Laboratory - Core

Administrative

CPT Codes

84403

TESTOSTERONE FREE AND TOTAL - ADULT MALES

LAB173

Collect

Serum separator tube or green (sodium or lithium heparin).

Patient Preparation

Collect between 6-10 a.m.

Specimen Preparation

Separate serum or plasma from cells ASAP or within 2 hours of collection. Transport 1 mL serum or plasma. (Min: 0.4 mL)

Unacceptable Conditions

EDTA plasma.

Storage/Transport Temperature

Frozen.

Stability (from collection to initiation)

After separation from cells: Ambient: 24 hours; Refrigerated: 1 week; Frozen: 2 months

Performed

Sun, Wed-Sat

Methodology

Quantitative Equilibrium Dialysis/High Performance Liquid Chromatography-Tandem Mass Spectrometry

Reported

1-6 days

Synonyms

  • LAB173
  • TE F&T ED

Ordering Recommendations

Laboratory reference method for determining free and total testosterone in men. Total or free testosterone is generally adequate for most evaluations of suspected hypogonadism.

Reference Interval

Male Free Testosterone, pg/mL
18 years and older: 47-244 pg/mL

Male Total Testosterone, ng/dL
18-39 years: 300-1080 ng/dL
40-59 years: 300-890 ng/dL
60 years and older: 300-720 ng/dL

CPT Codes

84402; 84403
Collection

LAB173

Collect

Serum separator tube or green (sodium or lithium heparin).

Patient Preparation

Collect between 6-10 a.m.

Specimen Preparation

Separate serum or plasma from cells ASAP or within 2 hours of collection. Transport 1 mL serum or plasma. (Min: 0.4 mL)

Unacceptable Conditions

EDTA plasma.

Storage/Transport Temperature

Frozen.

Stability (from collection to initiation)

After separation from cells: Ambient: 24 hours; Refrigerated: 1 week; Frozen: 2 months
Ordering

Performed

Sun, Wed-Sat

Methodology

Quantitative Equilibrium Dialysis/High Performance Liquid Chromatography-Tandem Mass Spectrometry

Reported

1-6 days

Synonyms

  • LAB173
  • TE F&T ED

Ordering Recommendations

Laboratory reference method for determining free and total testosterone in men. Total or free testosterone is generally adequate for most evaluations of suspected hypogonadism.
Result Interpretation

Reference Interval

Male Free Testosterone, pg/mL
18 years and older: 47-244 pg/mL

Male Total Testosterone, ng/dL
18-39 years: 300-1080 ng/dL
40-59 years: 300-890 ng/dL
60 years and older: 300-720 ng/dL

Administrative

CPT Codes

84402; 84403

TESTOSTERONE FREE, FEMALES OR CHILDREN

Collect

Serum separator tube or green (sodium or lithium heparin).

Patient Preparation

Collect between 6-10 a.m.

Specimen Preparation

Separate serum from cells ASAP or within 2 hours of collection. Transfer 1 mL serum or plasma to an ARUP Standard Transport Tube. (Min: 0.8 mL)

Unacceptable Conditions

EDTA plasma.

Storage/Transport Temperature

Refrigerated.

Stability (from collection to initiation)

After separation from cells: Ambient: 24 hours; Refrigerated: 1 week; Frozen: 6 months

Remarks

This test is suggested for women and children due to an improved sensitivity of testosterone by LC-MS/MS.

Notes

Testosterone Free, Females and Children by tandem mass spectrometry, only provides a result for the free testosterone value (pg/mL).

Performed

Sun-Sat

Methodology

Quantitative High Performance Liquid Chromatography-Tandem Mass Spectrometry/Electrochemiluminescent Immunoassay
Total Testosterone and SHBG are measured and free testosterone is estimated from these measurements.

Reported

1-4 days

Synonyms

  • TESTOS MAS
  • LAB8476

Ordering Recommendations

Most sensitive test for detection of hyperandrogenemia in women and children. Acceptable test for androgen deficiency in men.

Reference Interval

Female Free Testosterone, pg/mL
Male Free Testosterone, pg/mL
1-6 years: Less than 0.6 pg/mL
7-9 years: 0.6-1.8 pg/mL
10-11 years: 0.1-3.5 pg/mL
12-13 years: 0.9-6.8 pg/mL
14-15 years: 1.2-7.5 pg/mL
16-17 years: 1.2-9.9 pg/mL
18-30 years: 0.8-7.4 pg/mL
31-40 years: 1.3-9.2 pg/mL
41-51 years: 1.1-5.8 pg/mL
Postmenopausal: 0.6-3.8 pg/mL
Tanner Stage I: Less than 2.2 pg/mL
Tanner Stage II: 0.4-4.5 pg/mL
Tanner Stage III: 1.3-7.5 pg mL
Tanner Stage IV: 1.1-15.5 pg/mL
Tanner Stage V: 0.8-9.2 pg/mL		1-6 years: Less than 0.6 pg/mL
7-9 years: 0.1-0.9 pg/mL
10-11 years: 0.1-6.3 pg/mL
12-13 years: 0.5-98.0 pg/mL
14-15 years: 3-138.0 pg/mL
16-17 years: 38.0-173.0 pg/mL
18 years and older: 47-244 pg/mL
Tanner Stage I: Less than or equal to 3.7 pg/mL
Tanner Stage II: 0.3-21 pg/mL
Tanner Stage III: 1.0-98.0 pg mL
Tanner Stage IV: 35.0-169.0 pg/mL
Tanner Stage V: 41.0-239.0 pg/mL

Interpretive Data

The concentration of free testosterone is derived from a mathematical expression based on the constant for the binding of testosterone to SHBG.

CPT Codes

84402
Collection

Collect

Serum separator tube or green (sodium or lithium heparin).

Patient Preparation

Collect between 6-10 a.m.

Specimen Preparation

Separate serum from cells ASAP or within 2 hours of collection. Transfer 1 mL serum or plasma to an ARUP Standard Transport Tube. (Min: 0.8 mL)

Unacceptable Conditions

EDTA plasma.

Storage/Transport Temperature

Refrigerated.

Stability (from collection to initiation)

After separation from cells: Ambient: 24 hours; Refrigerated: 1 week; Frozen: 6 months

Remarks

This test is suggested for women and children due to an improved sensitivity of testosterone by LC-MS/MS.

Notes

Testosterone Free, Females and Children by tandem mass spectrometry, only provides a result for the free testosterone value (pg/mL).
Ordering

Performed

Sun-Sat

Methodology

Quantitative High Performance Liquid Chromatography-Tandem Mass Spectrometry/Electrochemiluminescent Immunoassay
Total Testosterone and SHBG are measured and free testosterone is estimated from these measurements.

Reported

1-4 days

Synonyms

  • TESTOS MAS
  • LAB8476

Ordering Recommendations

Most sensitive test for detection of hyperandrogenemia in women and children. Acceptable test for androgen deficiency in men.
Result Interpretation

Reference Interval

Female Free Testosterone, pg/mL
Male Free Testosterone, pg/mL
1-6 years: Less than 0.6 pg/mL
7-9 years: 0.6-1.8 pg/mL
10-11 years: 0.1-3.5 pg/mL
12-13 years: 0.9-6.8 pg/mL
14-15 years: 1.2-7.5 pg/mL
16-17 years: 1.2-9.9 pg/mL
18-30 years: 0.8-7.4 pg/mL
31-40 years: 1.3-9.2 pg/mL
41-51 years: 1.1-5.8 pg/mL
Postmenopausal: 0.6-3.8 pg/mL
Tanner Stage I: Less than 2.2 pg/mL
Tanner Stage II: 0.4-4.5 pg/mL
Tanner Stage III: 1.3-7.5 pg mL
Tanner Stage IV: 1.1-15.5 pg/mL
Tanner Stage V: 0.8-9.2 pg/mL		1-6 years: Less than 0.6 pg/mL
7-9 years: 0.1-0.9 pg/mL
10-11 years: 0.1-6.3 pg/mL
12-13 years: 0.5-98.0 pg/mL
14-15 years: 3-138.0 pg/mL
16-17 years: 38.0-173.0 pg/mL
18 years and older: 47-244 pg/mL
Tanner Stage I: Less than or equal to 3.7 pg/mL
Tanner Stage II: 0.3-21 pg/mL
Tanner Stage III: 1.0-98.0 pg mL
Tanner Stage IV: 35.0-169.0 pg/mL
Tanner Stage V: 41.0-239.0 pg/mL

Interpretive Data

The concentration of free testosterone is derived from a mathematical expression based on the constant for the binding of testosterone to SHBG.

Administrative

CPT Codes

84402

TETANUS ANTIBODY, IGG

LAB855

Collect

Serum separator tube. "Post" specimen should be drawn 30 days after immunization.

Specimen Preparation

Separate serum from cells ASAP or within 2 hours of collection. Transfer 1 mL serum to an ARUP Standard Transport Tube. (Min: 0.2 mL) "Pre" and "post" vaccine specimens can be submitted separately or together for testing; if shipped separately, "post" specimen must be received within 60 days of "pre" specimen. Mark specimens clearly as "Pre-Vaccine" or "Post-Vaccine".

Unacceptable Conditions

Plasma or other body fluids. Contaminated, hemolyzed, or severely lipemic specimens.

Storage/Transport Temperature

Refrigerated.

Stability (from collection to initiation)

After separation from cells: Ambient: 48 hours; Refrigerated: 2 weeks; Frozen: 1 year (avoid repeated freeze/thaw cycles)

Performed

Sun-Sat

Methodology

Quantitative Multiplex Bead Assay

Reported

1-2 days

Synonyms

  • LAB855

Ordering Recommendations

Evaluate the ability of a patient to produce antibody to pure protein vaccine after vaccination to rule out antibody deficiency.

Reference Interval

Antibody concentration of > 0.1 IU/mL is usually considered protective.

Interpretive Data

Responder status is determined according to the ratio of a one-month post-vaccination specimen to pre-vaccination concentration of tetanus IgG antibodies as follows:

1.  If the post-vaccination concentration is less than 1.0 IU, the patient is considered a nonresponder.
2.  If the post-vaccination concentration is greater than or equal to 1.0 IU, a patient with a ratio of less than 1.5 is a nonresponder, a ratio of 1.5 to less than 3.0, a weak responder, and a ratio of 3.0 or greater, a good responder.
3.  If the pre-vaccination concentration is greater than 1.0, it may be difficult to assess the response based on a ratio alone.  A post-vaccination concentration above 2.5 IU in this case is usually adequate.

CPT Codes

86317
Collection

LAB855

Collect

Serum separator tube. "Post" specimen should be drawn 30 days after immunization.

Specimen Preparation

Separate serum from cells ASAP or within 2 hours of collection. Transfer 1 mL serum to an ARUP Standard Transport Tube. (Min: 0.2 mL) "Pre" and "post" vaccine specimens can be submitted separately or together for testing; if shipped separately, "post" specimen must be received within 60 days of "pre" specimen. Mark specimens clearly as "Pre-Vaccine" or "Post-Vaccine".

Unacceptable Conditions

Plasma or other body fluids. Contaminated, hemolyzed, or severely lipemic specimens.

Storage/Transport Temperature

Refrigerated.

Stability (from collection to initiation)

After separation from cells: Ambient: 48 hours; Refrigerated: 2 weeks; Frozen: 1 year (avoid repeated freeze/thaw cycles)
Ordering

Performed

Sun-Sat

Methodology

Quantitative Multiplex Bead Assay

Reported

1-2 days

Synonyms

  • LAB855

Ordering Recommendations

Evaluate the ability of a patient to produce antibody to pure protein vaccine after vaccination to rule out antibody deficiency.
Result Interpretation

Reference Interval

Antibody concentration of > 0.1 IU/mL is usually considered protective.

Interpretive Data

Responder status is determined according to the ratio of a one-month post-vaccination specimen to pre-vaccination concentration of tetanus IgG antibodies as follows:

1.  If the post-vaccination concentration is less than 1.0 IU, the patient is considered a nonresponder.
2.  If the post-vaccination concentration is greater than or equal to 1.0 IU, a patient with a ratio of less than 1.5 is a nonresponder, a ratio of 1.5 to less than 3.0, a weak responder, and a ratio of 3.0 or greater, a good responder.
3.  If the pre-vaccination concentration is greater than 1.0, it may be difficult to assess the response based on a ratio alone.  A post-vaccination concentration above 2.5 IU in this case is usually adequate.

Administrative

CPT Codes

86317

THEOPHYLLINE

LAB35

THEOPH

Collect

One 4.5 mL Green top tube with gel separator (PST).

Pediatric Collection

1 mL whole blood or 20 capillary tubes.

Unacceptable Conditions

Specimen not properly identified; incorrect container; insufficient sample volume.

Storage/Transport Temperature

Internal: Deliver to lab immediately.
Offsite: Centrifuge within 30 minutes of collection. Send at 2-8 degrees C if tested within 24 hours. Place plasma in aliquot container and send frozen if not tested within 24 hours.

Stability (from collection to initiation)

Refrigerated: 24 hours; Frozen (-20 degrees C): Greater than 24 hours.

Remarks

Include dosage information. Trough levels should be drawn immediately before the next dose for oral dosing. For IV dosing, the patient should be at steady state during administration, or the specimen should be collected 30 minutes after completion of IV dose.

Collect at any time if toxicity is suspected..

Performed by

PCL Clinical Laboratory - Core

Performed

Daily

Methodology

Enzymatic

Reported

Same day

Synonyms

  • LAB35

Reference Interval

10.0-20.0 ug/mL

Interpretive Data

If this specimen had been tested prior to 05/20/2014, the result may have been 10% less than this value due to a different testing method.
In most patients, serum concentrations of 10–20 μg/mL effectively suppress chronic asthmatic and other bronchospastic symptoms. Serum concentrations of 5–10 μg/mL reportedly control apneic spells in neonates without causing apparent side effects. Peak concentrations above 20 μg/mL are often associated with toxicity.  For effective treatment, some patients may require serum levels outside this range. Therefore, the expected range is provided only as a general guide, and individual patient results should be interpreted in light of other clinical signs and symptoms.

Performed by

PCL Clinical Laboratory - Core

CPT Codes

80198

Collection

LAB35

THEOPH

Collect

One 4.5 mL Green top tube with gel separator (PST).

Pediatric Collection

1 mL whole blood or 20 capillary tubes.

Unacceptable Conditions

Specimen not properly identified; incorrect container; insufficient sample volume.

Storage/Transport Temperature

Internal: Deliver to lab immediately.
Offsite: Centrifuge within 30 minutes of collection. Send at 2-8 degrees C if tested within 24 hours. Place plasma in aliquot container and send frozen if not tested within 24 hours.

Stability (from collection to initiation)

Refrigerated: 24 hours; Frozen (-20 degrees C): Greater than 24 hours.

Remarks

Include dosage information. Trough levels should be drawn immediately before the next dose for oral dosing. For IV dosing, the patient should be at steady state during administration, or the specimen should be collected 30 minutes after completion of IV dose.

Collect at any time if toxicity is suspected..

Performed by

PCL Clinical Laboratory - Core

Ordering

Performed

Daily

Methodology

Enzymatic

Reported

Same day

Synonyms

  • LAB35
Result Interpretation

Reference Interval

10.0-20.0 ug/mL

Interpretive Data

If this specimen had been tested prior to 05/20/2014, the result may have been 10% less than this value due to a different testing method.
In most patients, serum concentrations of 10–20 μg/mL effectively suppress chronic asthmatic and other bronchospastic symptoms. Serum concentrations of 5–10 μg/mL reportedly control apneic spells in neonates without causing apparent side effects. Peak concentrations above 20 μg/mL are often associated with toxicity.  For effective treatment, some patients may require serum levels outside this range. Therefore, the expected range is provided only as a general guide, and individual patient results should be interpreted in light of other clinical signs and symptoms.

Performed by

PCL Clinical Laboratory - Core

Administrative

CPT Codes

80198

THIOCYANATE

LAB3042

Collect

Plain Red, Lavender (K2EDTA), Lavender (K3EDTA), or Pink (K2EDTA).

Specimen Preparation

Separate from cells ASAP or within 2 hours of collection. Transfer 1 mL serum or plasma to an ARUP Standard Transport Tube. (Min: 0.5 mL)

Unacceptable Conditions

Whole blood. Gel Separator Tubes, Light Blue (Sodium Citrate), or Yellow (SPS or ACD Solution).

Storage/Transport Temperature

Refrigerated.

Stability (from collection to initiation)

Ambient: 5 days; Refrigerated: 5 days; Frozen: 5 days

Remarks

Please indicate in the supplied fields:
1.  Dose - List drug amount and include the units of measure
2.  Route - List the route of administration (IV, oral, etc.)
3.  Dose Frequency - Indicate how often the dose is administered (per day, per week, as needed, etc.)
4.  Type of Draw - Indicate the type of blood draw (Peak, Trough, Random, etc.)

Notes

N/A

Performed

Mon, Fri

Methodology

Quantitative Colorimetry

Reported

1-5 days

Synonyms

  • LAB3042
  • THIO S

Additional Technical Information

Ordering Recommendations

Therapeutic monitoring in patients receiving sodium nitroprusside therapy. Screen for thiocyanate poisoning.

Reference Interval

Nonsmoker:  1-4 µg/mL
Smoker:  3-12 µg/mL
Toxic:  Greater than 50 µg/mL
Values seen with nitroprusside therapy:  6-29 µg/mL

Interpretive Data

The therapeutic range is based on serum pre-dose (trough) draw at steady-state concentration.

CPT Codes

84430
Collection

LAB3042

Collect

Plain Red, Lavender (K2EDTA), Lavender (K3EDTA), or Pink (K2EDTA).

Specimen Preparation

Separate from cells ASAP or within 2 hours of collection. Transfer 1 mL serum or plasma to an ARUP Standard Transport Tube. (Min: 0.5 mL)

Unacceptable Conditions

Whole blood. Gel Separator Tubes, Light Blue (Sodium Citrate), or Yellow (SPS or ACD Solution).

Storage/Transport Temperature

Refrigerated.

Stability (from collection to initiation)

Ambient: 5 days; Refrigerated: 5 days; Frozen: 5 days

Remarks

Please indicate in the supplied fields:
1.  Dose - List drug amount and include the units of measure
2.  Route - List the route of administration (IV, oral, etc.)
3.  Dose Frequency - Indicate how often the dose is administered (per day, per week, as needed, etc.)
4.  Type of Draw - Indicate the type of blood draw (Peak, Trough, Random, etc.)

Notes

N/A
Ordering

Performed

Mon, Fri

Methodology

Quantitative Colorimetry

Reported

1-5 days

Synonyms

  • LAB3042
  • THIO S

Additional Technical Information

Ordering Recommendations

Therapeutic monitoring in patients receiving sodium nitroprusside therapy. Screen for thiocyanate poisoning.
Result Interpretation

Reference Interval

Nonsmoker:  1-4 µg/mL
Smoker:  3-12 µg/mL
Toxic:  Greater than 50 µg/mL
Values seen with nitroprusside therapy:  6-29 µg/mL

Interpretive Data

The therapeutic range is based on serum pre-dose (trough) draw at steady-state concentration.

Administrative

CPT Codes

84430

THIOPURINE DRUG METABOLITES

LAB4967

THIOPMET

Collect

Lavender (EDTA), pink (K2EDTA)

Specimen Preparation

Transport 5 mL whole blood. (Min: 3.5 mL)

Unacceptable Conditions

Frozen samples, Hemolyzed samples.

Storage/Transport Temperature

Refrigerated.

Stability (from collection to initiation)

Ambient: 72 hours; Refrigerated: 8 days; Frozen: Unacceptable

Performed

Tue, Thu, Sun

Methodology

Quantitative Liquid Chromatography/Tandem Mass Spectrometry

Reported

1-5 days

Synonyms

  • IMURAN METABOLITES
  • AZATHIOPURINE METABOLITES
  • THIOPMET
  • TPMT (Thiopurine Drug Metabolites)

Ordering Recommendations

Optimize therapy for thiopurine drugs. Identify thiopurine metabolite concentrations that may lead to toxicity.

Reference Interval

Components
Reference Interval
6-TG Nucleotides RBC230-400 pmol/8 x 108 RBC
6-MMP Nucleotides RBCLess than 5701 pmol/8 x 108 RBC

Interpretive Data

Concentrations of 6-thioguanine nucleotide (6-TGN) less than 230 pmol/8 x 108 RBC may indicate a reduced response to therapy; 6-TGN concentrations greater than 400 pmol/8 x 108 RBC may indicate a higher risk for leukopenia. Concentrations of 6-methyl mercaptopurine nucleotide (6-MMPN) greater than 5700 pmol/8 x 108 RBC may indicate a higher risk for hepatotoxicity.

CPT Codes

80299 x2 (Alt code: G0480)
Collection

LAB4967

THIOPMET

Collect

Lavender (EDTA), pink (K2EDTA)

Specimen Preparation

Transport 5 mL whole blood. (Min: 3.5 mL)

Unacceptable Conditions

Frozen samples, Hemolyzed samples.

Storage/Transport Temperature

Refrigerated.

Stability (from collection to initiation)

Ambient: 72 hours; Refrigerated: 8 days; Frozen: Unacceptable
Ordering

Performed

Tue, Thu, Sun

Methodology

Quantitative Liquid Chromatography/Tandem Mass Spectrometry

Reported

1-5 days

Synonyms

  • IMURAN METABOLITES
  • AZATHIOPURINE METABOLITES
  • THIOPMET
  • TPMT (Thiopurine Drug Metabolites)

Ordering Recommendations

Optimize therapy for thiopurine drugs. Identify thiopurine metabolite concentrations that may lead to toxicity.
Result Interpretation

Reference Interval

Components
Reference Interval
6-TG Nucleotides RBC230-400 pmol/8 x 108 RBC
6-MMP Nucleotides RBCLess than 5701 pmol/8 x 108 RBC

Interpretive Data

Concentrations of 6-thioguanine nucleotide (6-TGN) less than 230 pmol/8 x 108 RBC may indicate a reduced response to therapy; 6-TGN concentrations greater than 400 pmol/8 x 108 RBC may indicate a higher risk for leukopenia. Concentrations of 6-methyl mercaptopurine nucleotide (6-MMPN) greater than 5700 pmol/8 x 108 RBC may indicate a higher risk for hepatotoxicity.

Administrative

CPT Codes

80299 x2 (Alt code: G0480)

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