THROAT CULTURE, GROUP A STREP ONLY

LAB228

Collect

Copan e-Swab of tonsillar area. Dry swabs are acceptable.

Storage/Transport Temperature

Internal: Deliver to lab immediately.
Offsite: Maintain specimen at ambient temperature. Deliver to Micro lab same day.

Stability (from collection to initiation)

Ambient: One day

Remarks

Do not swab throat in cases of acute epiglottitis unless provisions to establish an alternate airway are readily available.

Performed by

PCL Clinical Laboratory - Microbiology

Performed

Daily

Methodology

Culture

Reported

Varies

Synonyms

  • LAB228

Performed by

PCL Clinical Laboratory - Microbiology

CPT Codes

87075

Collection

LAB228

Collect

Copan e-Swab of tonsillar area. Dry swabs are acceptable.

Storage/Transport Temperature

Internal: Deliver to lab immediately.
Offsite: Maintain specimen at ambient temperature. Deliver to Micro lab same day.

Stability (from collection to initiation)

Ambient: One day

Remarks

Do not swab throat in cases of acute epiglottitis unless provisions to establish an alternate airway are readily available.

Performed by

PCL Clinical Laboratory - Microbiology

Ordering

Performed

Daily

Methodology

Culture

Reported

Varies

Synonyms

  • LAB228
Result Interpretation

Performed by

PCL Clinical Laboratory - Microbiology

Administrative

CPT Codes

87075

THROMBELASTOGRAM

LAB1122

Collect

One 2.7 mL blue top, 3.2% citrated plasma, filled to at least 80% capacity.

Unacceptable Conditions

Clotted samples; citrated tube less than 80% full; samples sent directly to the lab without calling the O.R. Laboratory Tech Phone at 720-848-5309; sample greater than 2 hours old; sample not properly identified; incorrect container; insufficient sample volume.

Storage/Transport Temperature

Internal: Transport at ambient temperature. O.R. Suite Anesthesiologist should contact O.R. Laboratory Tech prior to collection.
Offsite: Transport at room temperature. Non-O.R. requests from PCL Anesthesia staff should be arranged well in advance by calling the O.R. Laboratory Tech.

O.R.Laboratory Tech Phone is 720-848-5309.

Stability (from collection to initiation)

Ambient, 2 hours; Refrigerated, unacceptable; Frozen, unacceptable.

When collecting multiple timed samples, best accuracy is obtained by submitting specimens within 10 minutes of collection.

Remarks

O.R. Units: Call OR tech at 720-848-5309 for sample pickup.
Non-O.R. Units: Call OR tech at 720-848-5309 to schedule.

If drawing from a central line, clear the line by drawing and discarding the first 10 mL of blood. If collecting by venipuncture, discard the first 2 mL of blood.

Performed by

PCL Clinical Laboratory - Core

Performed

Daily

Methodology

Viscosity/elasticity during clot formation

Reported

Same day

Synonyms

  • LAB1122
  • Thromboelastogram
  • TEG

Reference Interval

TEG Reaction Time: 5.0 - 8.5 minutes

TEG Coagulation Time: 1.5 - 3.0 minutes

Performed by

PCL Clinical Laboratory - Core

CPT Codes

85396

Collection

LAB1122

Collect

One 2.7 mL blue top, 3.2% citrated plasma, filled to at least 80% capacity.

Unacceptable Conditions

Clotted samples; citrated tube less than 80% full; samples sent directly to the lab without calling the O.R. Laboratory Tech Phone at 720-848-5309; sample greater than 2 hours old; sample not properly identified; incorrect container; insufficient sample volume.

Storage/Transport Temperature

Internal: Transport at ambient temperature. O.R. Suite Anesthesiologist should contact O.R. Laboratory Tech prior to collection.
Offsite: Transport at room temperature. Non-O.R. requests from PCL Anesthesia staff should be arranged well in advance by calling the O.R. Laboratory Tech.

O.R.Laboratory Tech Phone is 720-848-5309.

Stability (from collection to initiation)

Ambient, 2 hours; Refrigerated, unacceptable; Frozen, unacceptable.

When collecting multiple timed samples, best accuracy is obtained by submitting specimens within 10 minutes of collection.

Remarks

O.R. Units: Call OR tech at 720-848-5309 for sample pickup.
Non-O.R. Units: Call OR tech at 720-848-5309 to schedule.

If drawing from a central line, clear the line by drawing and discarding the first 10 mL of blood. If collecting by venipuncture, discard the first 2 mL of blood.

Performed by

PCL Clinical Laboratory - Core

Ordering

Performed

Daily

Methodology

Viscosity/elasticity during clot formation

Reported

Same day

Synonyms

  • LAB1122
  • Thromboelastogram
  • TEG
Result Interpretation

Reference Interval

TEG Reaction Time: 5.0 - 8.5 minutes

TEG Coagulation Time: 1.5 - 3.0 minutes

Performed by

PCL Clinical Laboratory - Core

Administrative

CPT Codes

85396

THROMBIN TIME

LAB1122

Collect

One 2.7 mL blue top, 3.2% citrated plasma, filled to at least 80% capacity.

Unacceptable Conditions

Clotted samples; citrated tube less than 80% full; samples sent directly to the lab without calling the O.R. Laboratory Tech Phone at 720-848-5309; sample greater than 2 hours old; sample not properly identified; incorrect container; insufficient sample volume.

Storage/Transport Temperature

Internal: Transport at ambient temperature. O.R. Suite Anesthesiologist should contact O.R. Laboratory Tech prior to collection.
Offsite: Transport at room temperature. Non-O.R. requests from PCL Anesthesia staff should be arranged well in advance by calling the O.R. Laboratory Tech.

O.R.Laboratory Tech Phone is 720-848-5309.

Stability (from collection to initiation)

Ambient, 2 hours; Refrigerated, unacceptable; Frozen, unacceptable.

When collecting multiple timed samples, best accuracy is obtained by submitting specimens within 10 minutes of collection.

Remarks

O.R. Units: Call OR tech at 720-848-5309 for sample pickup.
Non-O.R. Units: Call OR tech at 720-848-5309 to schedule.

If drawing from a central line, clear the line by drawing and discarding the first 10 mL of blood. If collecting by venipuncture, discard the first 2 mL of blood.

Performed by

PCL Clinical Laboratory - Core

Performed

Daily

Methodology

Viscosity/elasticity during clot formation

Reported

Same day

Synonyms

  • LAB1122
  • Thromboelastogram
  • TEG

Reference Interval

TEG Reaction Time: 5.0 - 8.5 minutes

TEG Coagulation Time: 1.5 - 3.0 minutes

Performed by

PCL Clinical Laboratory - Core

CPT Codes

85396

Collection

LAB1122

Collect

One 2.7 mL blue top, 3.2% citrated plasma, filled to at least 80% capacity.

Unacceptable Conditions

Clotted samples; citrated tube less than 80% full; samples sent directly to the lab without calling the O.R. Laboratory Tech Phone at 720-848-5309; sample greater than 2 hours old; sample not properly identified; incorrect container; insufficient sample volume.

Storage/Transport Temperature

Internal: Transport at ambient temperature. O.R. Suite Anesthesiologist should contact O.R. Laboratory Tech prior to collection.
Offsite: Transport at room temperature. Non-O.R. requests from PCL Anesthesia staff should be arranged well in advance by calling the O.R. Laboratory Tech.

O.R.Laboratory Tech Phone is 720-848-5309.

Stability (from collection to initiation)

Ambient, 2 hours; Refrigerated, unacceptable; Frozen, unacceptable.

When collecting multiple timed samples, best accuracy is obtained by submitting specimens within 10 minutes of collection.

Remarks

O.R. Units: Call OR tech at 720-848-5309 for sample pickup.
Non-O.R. Units: Call OR tech at 720-848-5309 to schedule.

If drawing from a central line, clear the line by drawing and discarding the first 10 mL of blood. If collecting by venipuncture, discard the first 2 mL of blood.

Performed by

PCL Clinical Laboratory - Core

Ordering

Performed

Daily

Methodology

Viscosity/elasticity during clot formation

Reported

Same day

Synonyms

  • LAB1122
  • Thromboelastogram
  • TEG
Result Interpretation

Reference Interval

TEG Reaction Time: 5.0 - 8.5 minutes

TEG Coagulation Time: 1.5 - 3.0 minutes

Performed by

PCL Clinical Laboratory - Core

Administrative

CPT Codes

85396

THYROGLOBULIN ANTIBODIES

LAB515

THY AB

Collect

One 4.5 mL Gold top tube with gel separator (SST).

Pediatric Collection

Minimum volume = 0.25 mL serum

Unacceptable Conditions

Specimen not properly identified; incorrect container; insufficient sample volume; specimens thawed more than one time.

Storage/Transport Temperature

Internal: Deliver to lab immediately
Offsite: Allow sample to clot for at least 30 minutes and then centrifuge.Send at 2-8 degrees C if tested within 48 hours. Place serum in aliquot container and send frozen if not tested within 48 hours

Stability (from collection to initiation)

After centrifugation:  Ambient, 8 hours; Refrigerated, 2 days; Frozen (-20 degrees C): undetermined.

Note: Non-gel serum tubes (Red top) must have serum removed from cells if refrigerated or frozen.

Serum aliquot: Ambient, 8 hours; Refrigerated, 2 days; Frozen (-20 degrees C), Unknown.

Frozen samples may only be thawed one time

Performed by

PCL Clinical Laboratory - Core

Performed

Upon receipt.

Methodology

Chemiluminescent Immunoassay

Reported

Same day

Reference Interval

Thyroglobulin Antibody: < 4 IU/mL

Performed by

PCL Clinical Laboratory - Core

CPT Codes

86800

Collection

LAB515

THY AB

Collect

One 4.5 mL Gold top tube with gel separator (SST).

Pediatric Collection

Minimum volume = 0.25 mL serum

Unacceptable Conditions

Specimen not properly identified; incorrect container; insufficient sample volume; specimens thawed more than one time.

Storage/Transport Temperature

Internal: Deliver to lab immediately
Offsite: Allow sample to clot for at least 30 minutes and then centrifuge.Send at 2-8 degrees C if tested within 48 hours. Place serum in aliquot container and send frozen if not tested within 48 hours

Stability (from collection to initiation)

After centrifugation:  Ambient, 8 hours; Refrigerated, 2 days; Frozen (-20 degrees C): undetermined.

Note: Non-gel serum tubes (Red top) must have serum removed from cells if refrigerated or frozen.

Serum aliquot: Ambient, 8 hours; Refrigerated, 2 days; Frozen (-20 degrees C), Unknown.

Frozen samples may only be thawed one time

Performed by

PCL Clinical Laboratory - Core

Ordering

Performed

Upon receipt.

Methodology

Chemiluminescent Immunoassay

Reported

Same day

Result Interpretation

Reference Interval

Thyroglobulin Antibody: < 4 IU/mL

Performed by

PCL Clinical Laboratory - Core

Administrative

CPT Codes

86800

THYROGLOBULIN PANEL

LAB5516

TGLOB

Collect

One 4.5 mL Gold top tube with gel separator (SST).

Unacceptable Conditions

Specimen not properly identified; incorrect container; insufficient sample volume; specimens thawed more than one time.

Storage/Transport Temperature

Internal: Deliver to lab immediately
Offsite: Allow sample to clot for at least 30 minutes and then centrifuge.Send at 2-8 degrees C if tested within 48 hours. Place serum in aliquot container and send frozen if not tested within 48 hours.

Stability (from collection to initiation)

After centrifugation:  Ambient, 8 hours; Refrigerated, 2 days; Frozen (-20 degrees C): undetermined.

Note: Non-gel serum tubes (Red top) must have serum removed from cells if refrigerated or frozen.

Serum aliquot: Ambient, 8 hours; Refrigerated, 2 days; Frozen (-20 degrees C), Unknown.

Frozen samples may only be thawed one time.

Performed by

PCL Clinical Laboratory - Core

Notes

PANEL INCLUDES: Thyroglobulin & Throglobulin Antibody

Performed

Upon receipt

Methodology

Chemiluminescent Immunoassay

Reported

Same day

Synonyms

  • TGLOBPNL

Reference Interval

Thyroglobulin Quant: 1.6 - 50.0 ng/mL

Thyroglobulin Antibody: < 4 iu/mL

Performed by

PCL Clinical Laboratory - Core

CPT Codes

84432; 86800

Collection

LAB5516

TGLOB

Collect

One 4.5 mL Gold top tube with gel separator (SST).

Unacceptable Conditions

Specimen not properly identified; incorrect container; insufficient sample volume; specimens thawed more than one time.

Storage/Transport Temperature

Internal: Deliver to lab immediately
Offsite: Allow sample to clot for at least 30 minutes and then centrifuge.Send at 2-8 degrees C if tested within 48 hours. Place serum in aliquot container and send frozen if not tested within 48 hours.

Stability (from collection to initiation)

After centrifugation:  Ambient, 8 hours; Refrigerated, 2 days; Frozen (-20 degrees C): undetermined.

Note: Non-gel serum tubes (Red top) must have serum removed from cells if refrigerated or frozen.

Serum aliquot: Ambient, 8 hours; Refrigerated, 2 days; Frozen (-20 degrees C), Unknown.

Frozen samples may only be thawed one time.

Performed by

PCL Clinical Laboratory - Core

Notes

PANEL INCLUDES: Thyroglobulin & Throglobulin Antibody

Ordering

Performed

Upon receipt

Methodology

Chemiluminescent Immunoassay

Reported

Same day

Synonyms

  • TGLOBPNL
Result Interpretation

Reference Interval

Thyroglobulin Quant: 1.6 - 50.0 ng/mL

Thyroglobulin Antibody: < 4 iu/mL

Performed by

PCL Clinical Laboratory - Core

Administrative

CPT Codes

84432; 86800

THYROID ANTIBODIES

LAB3023

THYROID PAN

Collect

One 4.5 ml Gold top tube with gel seperator (SST).

Storage/Transport Temperature

Internal: Deliver to lab immediately.

Offsite: Allow sample to clot for at least 30 minutes and then centrifuge.  Send at 2-8 degrees C if tested within 48 hours.  Place serum in aliquot container and send frozen if not tested within 48 hours.

Stability (from collection to initiation)

After centrifugation:  Ambient, 8 hours; Refrigerated, 2 days; Frozen (-20 degrees C), undetermined

Note: Non-gel serum tubes (Red top) must have serum removed from cells if refrigerated or frozen.

Serum aliquot:  Ambient, 8 hours; Refrigerated, 2 days; Frozen (-20 degrees C), Unknown

Frozen samples may be thawed no more than one time.

Performed by

PCL Clinical Laboratory - Core

Notes

Panel Includes: TPO Antibody & Thyroglobulin Antibody

Performed

Upon Receipt

Methodology

Chemiluminescent Immunoassay

Reported

Same day.

Synonyms

  • LAB3023
  • THYROID PANEL
  • TPO Antibodies
  • Thyroid Peroxidase Antibodies
  • Thyroglobulin Antibodies

Reference Interval

TPOAB: 89% of euthyroid individuals have values <60U/mL. In patients with appropriate clinical finding, a value >60 U/mL, increases the likelihood that an autoimmune thyroid disease is present.

THYROGLOBULIN ANTIBODY: < 4 iu/mL

Performed by

PCL Clinical Laboratory - Core

CPT Codes

86376; 86800

Collection

LAB3023

THYROID PAN

Collect

One 4.5 ml Gold top tube with gel seperator (SST).

Storage/Transport Temperature

Internal: Deliver to lab immediately.

Offsite: Allow sample to clot for at least 30 minutes and then centrifuge.  Send at 2-8 degrees C if tested within 48 hours.  Place serum in aliquot container and send frozen if not tested within 48 hours.

Stability (from collection to initiation)

After centrifugation:  Ambient, 8 hours; Refrigerated, 2 days; Frozen (-20 degrees C), undetermined

Note: Non-gel serum tubes (Red top) must have serum removed from cells if refrigerated or frozen.

Serum aliquot:  Ambient, 8 hours; Refrigerated, 2 days; Frozen (-20 degrees C), Unknown

Frozen samples may be thawed no more than one time.

Performed by

PCL Clinical Laboratory - Core

Notes

Panel Includes: TPO Antibody & Thyroglobulin Antibody

Ordering

Performed

Upon Receipt

Methodology

Chemiluminescent Immunoassay

Reported

Same day.

Synonyms

  • LAB3023
  • THYROID PANEL
  • TPO Antibodies
  • Thyroid Peroxidase Antibodies
  • Thyroglobulin Antibodies
Result Interpretation

Reference Interval

TPOAB: 89% of euthyroid individuals have values <60U/mL. In patients with appropriate clinical finding, a value >60 U/mL, increases the likelihood that an autoimmune thyroid disease is present.

THYROGLOBULIN ANTIBODY: < 4 iu/mL

Performed by

PCL Clinical Laboratory - Core

Administrative

CPT Codes

86376; 86800

THYROID STIMULATING IMMUNOGLOB

LAB746

Collect

Plain red or serum separator tube.

Specimen Preparation

Transfer 1 mL serum to an ARUP Standard Transport Tube. (Min: 0.7 mL)

Unacceptable Conditions

Plasma.

Storage/Transport Temperature

Frozen.

Stability (from collection to initiation)

After separation from cells: Ambient: 24 hours; Refrigerated: 6 days; Frozen: 3 months

Notes

An elevated Thyroid Stimulating Hormone (TSH) value above 6 mU/L may produce a weakly positive Thyroid Stimulating Immunoglobulin (TSI) result (123 percent or greater).

Performed

Mon-Sat

Methodology

Quantitative Bioassay/Quantitative Chemiluminescent Immunoassay

Reported

2-5 days

Synonyms

  • TSI
  • LAB746

Additional Technical Information

Ordering Recommendations

Not routinely ordered. Preferred testing for autoimmune thyroid disease.

Reference Interval

Effective August 20, 2012
Negative122% basal activity or less
Positive123% basal activity or greater

Interpretive Data

Positive results (123 percent or greater) are consistent with Graves disease but do not always correlate with the presence and severity of hyperthyroidism. Antibodies to the Thyroid Stimulating Hormone Receptor (TSHR) may be stimulating, blocking, or neutral. Stimulating antibodies mimic the action of TSH and cause hyperthyroidism (Graves disease). This test determines the net effect of all TSHR antibody types present in the serum specimen.

CPT Codes

84445
Collection

LAB746

Collect

Plain red or serum separator tube.

Specimen Preparation

Transfer 1 mL serum to an ARUP Standard Transport Tube. (Min: 0.7 mL)

Unacceptable Conditions

Plasma.

Storage/Transport Temperature

Frozen.

Stability (from collection to initiation)

After separation from cells: Ambient: 24 hours; Refrigerated: 6 days; Frozen: 3 months

Notes

An elevated Thyroid Stimulating Hormone (TSH) value above 6 mU/L may produce a weakly positive Thyroid Stimulating Immunoglobulin (TSI) result (123 percent or greater).
Ordering

Performed

Mon-Sat

Methodology

Quantitative Bioassay/Quantitative Chemiluminescent Immunoassay

Reported

2-5 days

Synonyms

  • TSI
  • LAB746

Additional Technical Information

Ordering Recommendations

Not routinely ordered. Preferred testing for autoimmune thyroid disease.
Result Interpretation

Reference Interval

Effective August 20, 2012
Negative122% basal activity or less
Positive123% basal activity or greater

Interpretive Data

Positive results (123 percent or greater) are consistent with Graves disease but do not always correlate with the presence and severity of hyperthyroidism. Antibodies to the Thyroid Stimulating Hormone Receptor (TSHR) may be stimulating, blocking, or neutral. Stimulating antibodies mimic the action of TSH and cause hyperthyroidism (Graves disease). This test determines the net effect of all TSHR antibody types present in the serum specimen.

Administrative

CPT Codes

84445

THYROXINE BINDING GLOBULIN

LAB128

TBG

Collect

Serum separator tube.

Specimen Preparation

Transfer 0.5 mL serum to an ARUP Standard Transport Tube. (Min: 0.4 mL)

Unacceptable Conditions

Plasma, tissue or urine. Grossly hemolyzed or lipemic specimens.

Storage/Transport Temperature

Frozen.

Stability (from collection to initiation)

Ambient: 24 hours; Refrigerated: 1 week; Frozen: 1 month

Performed

Mon, Wed, Fri

Methodology

Quantitative Chemiluminescent Immunoassay

Reported

1-4 days

Synonyms

  • TBG
  • LAB128

Ordering Recommendations

Not recommended for routine thyroid screening.

Reference Interval

13.0-30.0 µg/mL

CPT Codes

84442
Collection

LAB128

TBG

Collect

Serum separator tube.

Specimen Preparation

Transfer 0.5 mL serum to an ARUP Standard Transport Tube. (Min: 0.4 mL)

Unacceptable Conditions

Plasma, tissue or urine. Grossly hemolyzed or lipemic specimens.

Storage/Transport Temperature

Frozen.

Stability (from collection to initiation)

Ambient: 24 hours; Refrigerated: 1 week; Frozen: 1 month
Ordering

Performed

Mon, Wed, Fri

Methodology

Quantitative Chemiluminescent Immunoassay

Reported

1-4 days

Synonyms

  • TBG
  • LAB128

Ordering Recommendations

Not recommended for routine thyroid screening.
Result Interpretation

Reference Interval

13.0-30.0 µg/mL
Administrative

CPT Codes

84442

TIAGABINE - GABATRIL

LAB497

Collect

Plain red or green (sodium or lithium heparin).

Patient Preparation

Trough collection.

Specimen Preparation

Transfer 3 mL serum or plasma to an ARUP Standard Transport Tube. (Min: 0.6 mL)

Unacceptable Conditions

Separator tubes.

Storage/Transport Temperature

Refrigerated . Also acceptable: Frozen

Stability (from collection to initiation)

Ambient: 72 hours; Refrigerated: 2 weeks; Frozen: 6 months

Performed

Varies

Methodology

Quantitative Liquid Chromatography/Tandem Mass Spectrometry

Reported

3-5 days

Synonyms

  • LAB497

Reference Interval

By report

CPT Codes

80199
Collection

LAB497

Collect

Plain red or green (sodium or lithium heparin).

Patient Preparation

Trough collection.

Specimen Preparation

Transfer 3 mL serum or plasma to an ARUP Standard Transport Tube. (Min: 0.6 mL)

Unacceptable Conditions

Separator tubes.

Storage/Transport Temperature

Refrigerated . Also acceptable: Frozen

Stability (from collection to initiation)

Ambient: 72 hours; Refrigerated: 2 weeks; Frozen: 6 months
Ordering

Performed

Varies

Methodology

Quantitative Liquid Chromatography/Tandem Mass Spectrometry

Reported

3-5 days

Synonyms

  • LAB497
Result Interpretation

Reference Interval

By report
Administrative

CPT Codes

80199

TOBRAMYCIN PEAK

LAB36

TOB P

Collect

One 4.5 mL Green top tube with gel separator (PST).

Pediatric Collection

1.5 mL whole blood or 20 full capillary tubes.

Unacceptable Conditions

Specimen not properly identified; incorrect container; insufficient sample volume.

Storage/Transport Temperature

Internal: Deliver to lab immediately
Offsite: Centrifuge within 30 minutes of collection. Send at 2-8 degrees C if tested within 24 hours. Place plasma in aliquot container and send frozen if not tested within 24 hours.

Stability (from collection to initiation)

Refrigerated: 24 hours; Frozen (-20 degrees C): Greater than 24 hours.

Remarks

Draw peak tobramycin levels 30 minutes after the end of a 30 - 60 minute infusion. Draw 60 minutes after an IM injection.

Performed by

PCL Clinical Laboratory - Core

Performed

Daily

Methodology

Enzymatic

Reported

Same day

Synonyms

  • LAB36
  • TOB P

Reference Interval

Effective 05/20/2014:

4 - 10 ug/mL

Interpretive Data

Effective 05/20/2014:

Although optimum concentrations vary according to the indication, for Q8 dosing, peak levels should be 5-10 ug/mL. For QD dosing peak levels are not necessary the majority of time, but should be >8 ug/mL. Prolonged peak concentrations above 12 μg/mL are often associated with ototoxicity when patients are on divided daily dosing regimens.  For effective treatment, some patients may require serum or plasma levels outside these ranges. Therefore, the expected ranges are provided only as general guidance, and individual patient results should be interpreted in light of clinical signs and symptoms.  Peaks should be drawn 30 minutes after the end of a 30-60 minute aminoglycoside infusion.

 

Before 05/20/2014:

REFERENCE RANGES: For Q8 dosing, peak levels should be 5-10 ug/mL and trough
levels should be less than 2 ug/mL.
For QD dosing peak levels are not necessary the majority of time, but should be greater than 8 ug/mL. Trough levels should be less than 1 ug/mL, with the level indicating a potential adjustment in dose if greater than 2 ug/mL.

Trough levels should be drawn immediately before the next dose. Peak levels should be drawn 30 minutes after the end of a 30-60 minute aminoglycoside infusion.

Performed by

PCL Clinical Laboratory - Core

CPT Codes

80200

Collection

LAB36

TOB P

Collect

One 4.5 mL Green top tube with gel separator (PST).

Pediatric Collection

1.5 mL whole blood or 20 full capillary tubes.

Unacceptable Conditions

Specimen not properly identified; incorrect container; insufficient sample volume.

Storage/Transport Temperature

Internal: Deliver to lab immediately
Offsite: Centrifuge within 30 minutes of collection. Send at 2-8 degrees C if tested within 24 hours. Place plasma in aliquot container and send frozen if not tested within 24 hours.

Stability (from collection to initiation)

Refrigerated: 24 hours; Frozen (-20 degrees C): Greater than 24 hours.

Remarks

Draw peak tobramycin levels 30 minutes after the end of a 30 - 60 minute infusion. Draw 60 minutes after an IM injection.

Performed by

PCL Clinical Laboratory - Core

Ordering

Performed

Daily

Methodology

Enzymatic

Reported

Same day

Synonyms

  • LAB36
  • TOB P
Result Interpretation

Reference Interval

Effective 05/20/2014:

4 - 10 ug/mL

Interpretive Data

Effective 05/20/2014:

Although optimum concentrations vary according to the indication, for Q8 dosing, peak levels should be 5-10 ug/mL. For QD dosing peak levels are not necessary the majority of time, but should be >8 ug/mL. Prolonged peak concentrations above 12 μg/mL are often associated with ototoxicity when patients are on divided daily dosing regimens.  For effective treatment, some patients may require serum or plasma levels outside these ranges. Therefore, the expected ranges are provided only as general guidance, and individual patient results should be interpreted in light of clinical signs and symptoms.  Peaks should be drawn 30 minutes after the end of a 30-60 minute aminoglycoside infusion.

 

Before 05/20/2014:

REFERENCE RANGES: For Q8 dosing, peak levels should be 5-10 ug/mL and trough
levels should be less than 2 ug/mL.
For QD dosing peak levels are not necessary the majority of time, but should be greater than 8 ug/mL. Trough levels should be less than 1 ug/mL, with the level indicating a potential adjustment in dose if greater than 2 ug/mL.

Trough levels should be drawn immediately before the next dose. Peak levels should be drawn 30 minutes after the end of a 30-60 minute aminoglycoside infusion.

Performed by

PCL Clinical Laboratory - Core

Administrative

CPT Codes

80200

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