Tests Catalogs

PLATELET FUNCT ASSAY - EPI/ADP

LAB318

 

Collect

Two 2.7 mL Blue tops (3.2% citrate plasma). DO NOT CENTRIFUGE.

All blue tops collected for coagulation assays which do not have a blood culture collected first must have a discard tube collected prior to filling.Discard tube should be another blue top in which greater than 1 mL of blood is collected.

Unacceptable Conditions

Samples received more than 4 hours after collection; samples sent in the pneumatic tube system; refrigerated or frozen samples; centrifuged or separated samples; tube fill volume less than 90% or greater than 110%; sample not properly identified; incorrect container; insufficient sample volume.

Storage/Transport Temperature

Internal: Deliver to lab immediately at ambient temperature.  Specimens must be hand-carried.  Do not use pneumatic tube system.
Offsite: DO NOT CENTRIFUGE. DO NOT REFRIGERATE. Transport to lab STAT at ambient temperature.

Laboratory Specimen Management Staff: Immediately log in test and give to Coag Tech.

Stability (from collection to initiation)

Ambient: 4 hours; Refrigerated: Unacceptable; Frozen: Unacceptable.

Remarks

Hours for PFA100 testing are Monday through Friday (except holidays), between 08:00 and 20:00.  Please call Special Coagulation laboratory at 720-848-6938 at time of collection.

TIME SENSITIVE TESTING - The samples must be tested within 4 hours of collection and MUST be received by the laboratory within 3 hours of collection.

Performed by

PCL Clinical Laboratory - Specials

Performed

Monday through Friday (except holidays), 8:00 AM - 8:00 PM

Methodology

Platelet Aggregation

Reported

Same day

Synonyms

  • LAB318

Reference Interval

PFA100-EPI: 66 - 169 seconds

PFA100-ADP: 50 - 118 seconds

Interpretive Data

Hematocrit less than 35% and/or Platelet Count less than 150,000/uL may cause prolonged test results.

Performed by

PCL Clinical Laboratory - Specials

CPT Codes

ADP 85576; EPI 85576

Collection

LAB318

 

Collect

Two 2.7 mL Blue tops (3.2% citrate plasma). DO NOT CENTRIFUGE.

All blue tops collected for coagulation assays which do not have a blood culture collected first must have a discard tube collected prior to filling.Discard tube should be another blue top in which greater than 1 mL of blood is collected.

Unacceptable Conditions

Samples received more than 4 hours after collection; samples sent in the pneumatic tube system; refrigerated or frozen samples; centrifuged or separated samples; tube fill volume less than 90% or greater than 110%; sample not properly identified; incorrect container; insufficient sample volume.

Storage/Transport Temperature

Internal: Deliver to lab immediately at ambient temperature.  Specimens must be hand-carried.  Do not use pneumatic tube system.
Offsite: DO NOT CENTRIFUGE. DO NOT REFRIGERATE. Transport to lab STAT at ambient temperature.

Laboratory Specimen Management Staff: Immediately log in test and give to Coag Tech.

Stability (from collection to initiation)

Ambient: 4 hours; Refrigerated: Unacceptable; Frozen: Unacceptable.

Remarks

Hours for PFA100 testing are Monday through Friday (except holidays), between 08:00 and 20:00.  Please call Special Coagulation laboratory at 720-848-6938 at time of collection.

TIME SENSITIVE TESTING - The samples must be tested within 4 hours of collection and MUST be received by the laboratory within 3 hours of collection.

Performed by

PCL Clinical Laboratory - Specials

Ordering

Performed

Monday through Friday (except holidays), 8:00 AM - 8:00 PM

Methodology

Platelet Aggregation

Reported

Same day

Synonyms

  • LAB318
Result Interpretation

Reference Interval

PFA100-EPI: 66 - 169 seconds

PFA100-ADP: 50 - 118 seconds

Interpretive Data

Hematocrit less than 35% and/or Platelet Count less than 150,000/uL may cause prolonged test results.

Performed by

PCL Clinical Laboratory - Specials

Administrative

CPT Codes

ADP 85576; EPI 85576

PML/RAR - t(15;17) BY RT-PCR

LAB3743

Collect

4.0 mL EDTA whole blood (or bone marrow in EDTA), PURPLE OR PINK TOP

Specimen Preparation

1.0 mL minimum volume

Unacceptable Conditions

Serum. Frozen

Storage/Transport Temperature

Ambient or refrigerated.

Performed by

Children's Hospital Colorado Molecular Diagnositics Laboratory

Performed

1 day a week; varies

Methodology

RT-PCR

Reported

7-10 days

Synonyms

  • PML/RARPCR
  • LAB3743

Reference Interval

No moleculare evidence of translocation.

Performed by

Children's Hospital Colorado Molecular Diagnositics Laboratory

CPT Codes

81315

Collection

LAB3743

Collect

4.0 mL EDTA whole blood (or bone marrow in EDTA), PURPLE OR PINK TOP

Specimen Preparation

1.0 mL minimum volume

Unacceptable Conditions

Serum. Frozen

Storage/Transport Temperature

Ambient or refrigerated.

Performed by

Children's Hospital Colorado Molecular Diagnositics Laboratory

Ordering

Performed

1 day a week; varies

Methodology

RT-PCR

Reported

7-10 days

Synonyms

  • PML/RARPCR
  • LAB3743
Result Interpretation

Reference Interval

No moleculare evidence of translocation.

Performed by

Children's Hospital Colorado Molecular Diagnositics Laboratory

Administrative

CPT Codes

81315

PM-SCL ANTIBODIES

LAB3117

 

Collect

4.5 mL Red top tube, no gel.

Specimen Preparation

1.0 mL serum (0.5 mL minimum volume serum)

Unacceptable Conditions

Tubes with gel.

Storage/Transport Temperature

Ship refrigerated.

Stability (from collection to initiation)

  Refrigerated (preferred) 14 days
  Frozen 30 days
  Ambient 7 days

Performed by

Quest Diagnostics Nichols Institute

Performed

Sunday, Monday, Tuesday, Thursday

Methodology

Immunodiffusion

Reported

4-12 days

Synonyms

  • -381 Anti-PM1 Andibody
  • ANTI-PM-SCL
  • PM-1 Antibody
  • Antibody to PM-1
  • LAB3117
  • ANTIPM1

Reference Interval

Negative

Interpretive Data

INTERPRETIVE CRITERIA:  Negative :  Antibody not detected

                                        Positive:   Antibody detected

PM-Scl antibody is detected in over 90% of patients with polymyositis

(PM) and scleroderma (Scl) overlap syndrome, but only in about 8% of

all myositis patients and only 3% of all scleroderma patients.

Performed by

Quest Diagnostics Nichols Institute

CPT Codes

86235

Collection

LAB3117

 

Collect

4.5 mL Red top tube, no gel.

Specimen Preparation

1.0 mL serum (0.5 mL minimum volume serum)

Unacceptable Conditions

Tubes with gel.

Storage/Transport Temperature

Ship refrigerated.

Stability (from collection to initiation)

  Refrigerated (preferred) 14 days
  Frozen 30 days
  Ambient 7 days

Performed by

Quest Diagnostics Nichols Institute

Ordering

Performed

Sunday, Monday, Tuesday, Thursday

Methodology

Immunodiffusion

Reported

4-12 days

Synonyms

  • -381 Anti-PM1 Andibody
  • ANTI-PM-SCL
  • PM-1 Antibody
  • Antibody to PM-1
  • LAB3117
  • ANTIPM1
Result Interpretation

Reference Interval

Negative

Interpretive Data

INTERPRETIVE CRITERIA:  Negative :  Antibody not detected

                                        Positive:   Antibody detected

PM-Scl antibody is detected in over 90% of patients with polymyositis

(PM) and scleroderma (Scl) overlap syndrome, but only in about 8% of

all myositis patients and only 3% of all scleroderma patients.

Performed by

Quest Diagnostics Nichols Institute

Administrative

CPT Codes

86235

PNEUMOCYSTIS (CARINII) JIROVECII by PCR

LAB8534

Collect

Respiratory specimen: Bronchoalveolar lavage (BAL), bronchial wash, or sputum.

Specimen Preparation

Transfer 2 mL respiratory specimen to a sterile container. (Min: 0.5 mL). Also acceptable: Transfer to viral transport media (ARUP supply #12884). Available online through eSupply using ARUP Connect™ or contact ARUP Client Services at (800) 522-2787.  Place each specimen in an individually sealed bag.

Storage/Transport Temperature

Frozen.

Stability (from collection to initiation)

Ambient: 48 hours; Refrigerated: 7 days; Frozen: 1 month.

Remarks

Specimen source required. Bronchoalveolar lavage (BAL), bronchial wash or induced sputum are the preferred specimen types. Expectorated sputum is acceptable but not preferred.

Performed

Mon, Wed, Fri

Methodology

Qualitative Polymerase Chain Reaction

Reported

1-5 days

Synonyms

  • P jirovecii DNA detection
  • P jirovecii PCR
  • P carinii PCR
  • Pneumocystis carinii PCR
  • LAB8534

Ordering Recommendations

Detect P. jirovecii. Preferred test for immunocompromised patients who do not have HIV.

CPT Codes

87798
Collection

LAB8534

Collect

Respiratory specimen: Bronchoalveolar lavage (BAL), bronchial wash, or sputum.

Specimen Preparation

Transfer 2 mL respiratory specimen to a sterile container. (Min: 0.5 mL). Also acceptable: Transfer to viral transport media (ARUP supply #12884). Available online through eSupply using ARUP Connect™ or contact ARUP Client Services at (800) 522-2787.  Place each specimen in an individually sealed bag.

Storage/Transport Temperature

Frozen.

Stability (from collection to initiation)

Ambient: 48 hours; Refrigerated: 7 days; Frozen: 1 month.

Remarks

Specimen source required. Bronchoalveolar lavage (BAL), bronchial wash or induced sputum are the preferred specimen types. Expectorated sputum is acceptable but not preferred.
Ordering

Performed

Mon, Wed, Fri

Methodology

Qualitative Polymerase Chain Reaction

Reported

1-5 days

Synonyms

  • P jirovecii DNA detection
  • P jirovecii PCR
  • P carinii PCR
  • Pneumocystis carinii PCR
  • LAB8534

Ordering Recommendations

Detect P. jirovecii. Preferred test for immunocompromised patients who do not have HIV.
Result Interpretation
Administrative

CPT Codes

87798

PNEUMOCYSTIS DIRECT FA

LAB3351
PCPDIRECT

 

Collect

2-3 mL induced sputum or brochial alveolar lavage (BAL) in a sterile container.

Pediatric Collection

0.5 mL minimum volume.

Unacceptable Conditions

Frozen samples; specimen not properly identified; incorrect container; insufficient sample volume; noninduced expectorated sputum; specimens in cytology preservative.

Storage/Transport Temperature

Internal: Deliver to lab immediately.
Offsite: Transport same day at 2-8 degrees C.

Stability (from collection to initiation)

Refrigerated: 24 hours; Frozen: Unacceptable.

Remarks

Sputum must be induced by Respiratory Therapy. Results are available by 15:30 if specimen arrives in laboratory before 11:00 AM daily.

Performed by

PCL Clinical Laboratory - Virology

Performed

Daily, dayshift

Methodology

Direct fluorescent stain.

Reported

Within 24 hours

Synonyms

  • LAB3351
  • PCPDIRECT
  • PCP DFA

Performed by

PCL Clinical Laboratory - Virology

CPT Codes

87281

Collection

LAB3351
PCPDIRECT

 

Collect

2-3 mL induced sputum or brochial alveolar lavage (BAL) in a sterile container.

Pediatric Collection

0.5 mL minimum volume.

Unacceptable Conditions

Frozen samples; specimen not properly identified; incorrect container; insufficient sample volume; noninduced expectorated sputum; specimens in cytology preservative.

Storage/Transport Temperature

Internal: Deliver to lab immediately.
Offsite: Transport same day at 2-8 degrees C.

Stability (from collection to initiation)

Refrigerated: 24 hours; Frozen: Unacceptable.

Remarks

Sputum must be induced by Respiratory Therapy. Results are available by 15:30 if specimen arrives in laboratory before 11:00 AM daily.

Performed by

PCL Clinical Laboratory - Virology

Ordering

Performed

Daily, dayshift

Methodology

Direct fluorescent stain.

Reported

Within 24 hours

Synonyms

  • LAB3351
  • PCPDIRECT
  • PCP DFA
Result Interpretation

Performed by

PCL Clinical Laboratory - Virology

Administrative

CPT Codes

87281

POLIOVIRUS ANTIBODIES TYPE 1-3

LAB653

 

Collect

Serum separator tube or plain red.

Specimen Preparation

Separate serum from cells within 2 hours of collection. Transport 1 mL serum. (Min: 0.2 mL)

Unacceptable Conditions

Plasma. Contaminated, hemolyzed, or severely lipemic specimens.

Storage/Transport Temperature

Refrigerated.

Stability (from collection to initiation)

After separation from cells: Ambient: 48 hours; Refrigerated: 2 weeks; Frozen: 1 year (avoid repeated freeze/thaw cycles)

Performed

Mon-Fri

Methodology

Semi-Quantitative Serum Neutralization

Reported

6-9 days

Synonyms

  • LAB653
  • POLIOVAB
  • POLIO

Ordering Recommendations

Detect neutralizing antibodies to polio virus.

Reference Interval

Less than 1:10:  No detectable poliovirus antibodies.
1:10 or greater: Antibody to poliovirus detected, which may represent prior immunization or current or past infection.

Interpretive Data

The presence of neutralizing antibodies against poliovirus implies immunity. The serum neutralization test is serotype specific. Antibodies against one type does not indicate immunity against other types.

Reference interval applies to Poliovirus Antibody Types 1, 2 and 3.

CPT Codes

86658 x3
Collection

LAB653

 

Collect

Serum separator tube or plain red.

Specimen Preparation

Separate serum from cells within 2 hours of collection. Transport 1 mL serum. (Min: 0.2 mL)

Unacceptable Conditions

Plasma. Contaminated, hemolyzed, or severely lipemic specimens.

Storage/Transport Temperature

Refrigerated.

Stability (from collection to initiation)

After separation from cells: Ambient: 48 hours; Refrigerated: 2 weeks; Frozen: 1 year (avoid repeated freeze/thaw cycles)
Ordering

Performed

Mon-Fri

Methodology

Semi-Quantitative Serum Neutralization

Reported

6-9 days

Synonyms

  • LAB653
  • POLIOVAB
  • POLIO

Ordering Recommendations

Detect neutralizing antibodies to polio virus.
Result Interpretation

Reference Interval

Less than 1:10:  No detectable poliovirus antibodies.
1:10 or greater: Antibody to poliovirus detected, which may represent prior immunization or current or past infection.

Interpretive Data

The presence of neutralizing antibodies against poliovirus implies immunity. The serum neutralization test is serotype specific. Antibodies against one type does not indicate immunity against other types.

Reference interval applies to Poliovirus Antibody Types 1, 2 and 3.

Administrative

CPT Codes

86658 x3

POLYOMAVIRUS (BK + JC) BY PCR

LAB3259

 

Collect

All sample types. Submit in a sterile container.

Pediatric Collection

1 mL minimum volume.

Unacceptable Conditions

Specimen not properly identified; incorrect container; insufficient sample volume. No fixatives allowed.

Storage/Transport Temperature

Internal: Deliver to lab immediately
Offsite: Transport same day at 2-8 degrees C. If delivery is not expected within 24 hours, freeze at -70 degrees C and ship on dry ice.

Stability (from collection to initiation)

Refrigerated: 72 hours.

Remarks

Quantitative results will be given for all blood, plasma, serum, and urine samples. Qualitative results will be given for tissues, stools, swabs, or diluted samples. Ordering this test will yield results for both BK and JC viruses. Please submit one requisition per sample.

Performed by

PCL Clinical Laboratory - Molecular Diagnostics

Performed

Mon - Fri

Methodology

DNA amplification by polymerase chain reaction (PCR) using a BK-specific and a JC-specific DNA probe detected by real-time PCR.

Reported

24-48 hours

Synonyms

  • LAB3259

Performed by

PCL Clinical Laboratory - Molecular Diagnostics

CPT Codes

87799 (2)

Collection

LAB3259

 

Collect

All sample types. Submit in a sterile container.

Pediatric Collection

1 mL minimum volume.

Unacceptable Conditions

Specimen not properly identified; incorrect container; insufficient sample volume. No fixatives allowed.

Storage/Transport Temperature

Internal: Deliver to lab immediately
Offsite: Transport same day at 2-8 degrees C. If delivery is not expected within 24 hours, freeze at -70 degrees C and ship on dry ice.

Stability (from collection to initiation)

Refrigerated: 72 hours.

Remarks

Quantitative results will be given for all blood, plasma, serum, and urine samples. Qualitative results will be given for tissues, stools, swabs, or diluted samples. Ordering this test will yield results for both BK and JC viruses. Please submit one requisition per sample.

Performed by

PCL Clinical Laboratory - Molecular Diagnostics

Ordering

Performed

Mon - Fri

Methodology

DNA amplification by polymerase chain reaction (PCR) using a BK-specific and a JC-specific DNA probe detected by real-time PCR.

Reported

24-48 hours

Synonyms

  • LAB3259
Result Interpretation

Performed by

PCL Clinical Laboratory - Molecular Diagnostics

Administrative

CPT Codes

87799 (2)

PORPHOBILINOGEN QUANT URINE

LAB3754

Collect

Random or 24-hour urine. Refrigerate 24-hour specimens during collection.

Specimen Preparation

Protect from light. Transfer 8 mL aliquot from a random or well-mixed 24-hour collection to ARUP Amber Transport Tubes. (Min: 3.5 mL) Record total volume and collection time interval on transport tube and test request form.

Unacceptable Conditions

Body fluids other than urine.

Storage/Transport Temperature

Frozen.

Stability (from collection to initiation)

Ambient: Unacceptable; Refrigerated: 4 days; Frozen: 1 month

Notes

Appropriate test to rule out acute intermittent porphyria (AIP) and other acute attack types of porphyrias associated with neurologic and/or psychiatric symptoms.

Performed

Mon-Fri

Methodology

Quantitative Ion Exchange Chromatography/Spectrophotometry

Reported

1-4 days

Synonyms

  • Porphyria, Acute
  • PBG, Urine Quantitative
  • LAB3754
  • PBGQT
  • PBGQU

Ordering Recommendations

Essential first-line test for suspected acute porphyria in adults. Use in determining metabolic response to IV hematin.

Reference Interval

Components
Reference Interval
Porphobilinogen (PBG), Urine -per volume0.0-8.8 µmol/L
Porphobilinogen, Urine - per 24h0.0-11.0 µmol/d
Creatinine, 24-Hour Urine
Age
Male
Female
3-8 years140-700 mg/d140-700 mg/d
9-12 years300-1300 mg/d300-1300 mg/d
13-17 years500-2300 mg/d400-1600 mg/d
18-50 years1000-2500 mg/d700-1600 mg/d
51-80 years800-2100 mg/d500-1400 mg/d
81 years and older600-2000 mg/d400-1300 mg/d


CPT Codes

84110
Collection

LAB3754

Collect

Random or 24-hour urine. Refrigerate 24-hour specimens during collection.

Specimen Preparation

Protect from light. Transfer 8 mL aliquot from a random or well-mixed 24-hour collection to ARUP Amber Transport Tubes. (Min: 3.5 mL) Record total volume and collection time interval on transport tube and test request form.

Unacceptable Conditions

Body fluids other than urine.

Storage/Transport Temperature

Frozen.

Stability (from collection to initiation)

Ambient: Unacceptable; Refrigerated: 4 days; Frozen: 1 month

Notes

Appropriate test to rule out acute intermittent porphyria (AIP) and other acute attack types of porphyrias associated with neurologic and/or psychiatric symptoms.
Ordering

Performed

Mon-Fri

Methodology

Quantitative Ion Exchange Chromatography/Spectrophotometry

Reported

1-4 days

Synonyms

  • Porphyria, Acute
  • PBG, Urine Quantitative
  • LAB3754
  • PBGQT
  • PBGQU

Ordering Recommendations

Essential first-line test for suspected acute porphyria in adults. Use in determining metabolic response to IV hematin.
Result Interpretation

Reference Interval

Components
Reference Interval
Porphobilinogen (PBG), Urine -per volume0.0-8.8 µmol/L
Porphobilinogen, Urine - per 24h0.0-11.0 µmol/d
Creatinine, 24-Hour Urine
Age
Male
Female
3-8 years140-700 mg/d140-700 mg/d
9-12 years300-1300 mg/d300-1300 mg/d
13-17 years500-2300 mg/d400-1600 mg/d
18-50 years1000-2500 mg/d700-1600 mg/d
51-80 years800-2100 mg/d500-1400 mg/d
81 years and older600-2000 mg/d400-1300 mg/d


Administrative

CPT Codes

84110

PORPHOBILINOGEN-DEAMINASE, ERYTHROCYTES

Collect

Lavender (EDTA) or pink (K2EDTA).

Patient Preparation

Perform automated hemoglobin on EDTA whole blood before preparing for transport.

Specimen Preparation

Transport 3 mL whole blood. (Min: 1 mL)

Unacceptable Conditions

Body fluid other than EDTA preserved whole blood. Clotted specimens.

Storage/Transport Temperature

Frozen.

Stability (from collection to initiation)

Ambient: 4 hours; Refrigerated: 1 week; Frozen: 1 month

Remarks

Automated hemoglobin result must be included with specimen.

Notes

This test is most useful for family studies to determine which family members are at risk for acute intermittent porphyria and is best performed in association with a specimen from the proband. Because of ambiguous results, this test is not generally recommended for diagnosis.

Performed

Tue, Thu

Methodology

Quantitative Enzymatic/Fluorometry

Reported

1-6 days

Synonyms

  • Hydroxymethylbilane Synthase
  • Uroporphyrinogen I Synthase
  • Porphyria Enzyme
  • Acute Intermittent Porphyria Enzyme

Ordering Recommendations

Use to confirm a diagnosis of acute intermittent porphyria (AIP) following a positive urine porphobilinogen (PBG) test. Use to evaluate disease risk in family members of an individual with a confirmed diagnosis of AIP.

Reference Interval

Adult: 2.10-4.30 mU/g Hb

Interpretive Data

Porphobilinogen (PBG) deaminase (hydroxymethylbilane synthase or uroporphyrinogen I synthase) is expressed in units of mU per gram hemoglobin at 37°C. In persons genetically susceptible to acute intermittent porphyria (AIP), PBG deaminase concentrations are approximately half of reference values. Normal concentrations of erythrocyte PBG deaminase may include abnormal forms of hepatic PBG deaminase.

CPT Codes

82657
Collection

Collect

Lavender (EDTA) or pink (K2EDTA).

Patient Preparation

Perform automated hemoglobin on EDTA whole blood before preparing for transport.

Specimen Preparation

Transport 3 mL whole blood. (Min: 1 mL)

Unacceptable Conditions

Body fluid other than EDTA preserved whole blood. Clotted specimens.

Storage/Transport Temperature

Frozen.

Stability (from collection to initiation)

Ambient: 4 hours; Refrigerated: 1 week; Frozen: 1 month

Remarks

Automated hemoglobin result must be included with specimen.

Notes

This test is most useful for family studies to determine which family members are at risk for acute intermittent porphyria and is best performed in association with a specimen from the proband. Because of ambiguous results, this test is not generally recommended for diagnosis.
Ordering

Performed

Tue, Thu

Methodology

Quantitative Enzymatic/Fluorometry

Reported

1-6 days

Synonyms

  • Hydroxymethylbilane Synthase
  • Uroporphyrinogen I Synthase
  • Porphyria Enzyme
  • Acute Intermittent Porphyria Enzyme

Ordering Recommendations

Use to confirm a diagnosis of acute intermittent porphyria (AIP) following a positive urine porphobilinogen (PBG) test. Use to evaluate disease risk in family members of an individual with a confirmed diagnosis of AIP.
Result Interpretation

Reference Interval

Adult: 2.10-4.30 mU/g Hb

Interpretive Data

Porphobilinogen (PBG) deaminase (hydroxymethylbilane synthase or uroporphyrinogen I synthase) is expressed in units of mU per gram hemoglobin at 37°C. In persons genetically susceptible to acute intermittent porphyria (AIP), PBG deaminase concentrations are approximately half of reference values. Normal concentrations of erythrocyte PBG deaminase may include abnormal forms of hepatic PBG deaminase.

Administrative

CPT Codes

82657

PORPHYRINS FECES

LAB3342

 

Collect

Random stool.

Specimen Preparation

Protect from light during collection, storage, and shipment. Freeze specimen and wrap in foil immediately after collection. Transport 5 g stool. (Min: 1 g)

Unacceptable Conditions

Complete timed collections (24-72 hour). Specimens stored in one gallon cans or other large containers. Liquid stool.

Storage/Transport Temperature

CRITICAL FROZEN. Separate specimens must be submitted when multiple tests are ordered.

Stability (from collection to initiation)

Ambient: Unacceptable; Refrigerated: Unacceptable; Frozen: 3 weeks

Notes

Bacterial modification of fecal porphyrins is extensive. The recommended specimen for uroporphyrin and coproporphyrin is urine (random or 24-hour). Refer to Porphyrins, Fractionation & Quantitation, Urine (ARUP test code 2002058). The recommended specimen for protoporphyrin is serum.  Refer to Porphyrins, Serum Total (ARUP test code 0080429). 

Performed

Mon, Thu

Methodology

Quantitative High Performance Liquid Chromatography

Reported

2-7 days

Synonyms

  • Coproporphyrin, Fecal
  • Protoporphyrin, Fecal
  • LAB3342
  • POR, FECAL
  • PORPHF

Ordering Recommendations

Distinguish among acute intermittent porphyria (AIP) , variegate porphyria (VP), and hereditary coproporphyria (HCP).

Reference Interval

Components
Reference Interval
Coproporphyrin, Feces0-45 nmol/g dry weight
Protoporphyrin, Feces0-100 nmol/g dry weight

CPT Codes

84126
Collection

LAB3342

 

Collect

Random stool.

Specimen Preparation

Protect from light during collection, storage, and shipment. Freeze specimen and wrap in foil immediately after collection. Transport 5 g stool. (Min: 1 g)

Unacceptable Conditions

Complete timed collections (24-72 hour). Specimens stored in one gallon cans or other large containers. Liquid stool.

Storage/Transport Temperature

CRITICAL FROZEN. Separate specimens must be submitted when multiple tests are ordered.

Stability (from collection to initiation)

Ambient: Unacceptable; Refrigerated: Unacceptable; Frozen: 3 weeks

Notes

Bacterial modification of fecal porphyrins is extensive. The recommended specimen for uroporphyrin and coproporphyrin is urine (random or 24-hour). Refer to Porphyrins, Fractionation & Quantitation, Urine (ARUP test code 2002058). The recommended specimen for protoporphyrin is serum.  Refer to Porphyrins, Serum Total (ARUP test code 0080429). 
Ordering

Performed

Mon, Thu

Methodology

Quantitative High Performance Liquid Chromatography

Reported

2-7 days

Synonyms

  • Coproporphyrin, Fecal
  • Protoporphyrin, Fecal
  • LAB3342
  • POR, FECAL
  • PORPHF

Ordering Recommendations

Distinguish among acute intermittent porphyria (AIP) , variegate porphyria (VP), and hereditary coproporphyria (HCP).
Result Interpretation

Reference Interval

Components
Reference Interval
Coproporphyrin, Feces0-45 nmol/g dry weight
Protoporphyrin, Feces0-100 nmol/g dry weight

Administrative

CPT Codes

84126

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