LAB3919
Collect
From either a supine or upright patient, Serum Separator Tube (SST) AND Lavender (EDTA) or Pink (K2EDTA). Do not collect in refrigerated tubes.
Patient Preparation
Normal sodium diet (100-200 mEq/day) for at least three days. Receiving no medications known to affect renin-aldosterone system.
Supine: Both specimens should be obtained between 8 a.m. and 10 a.m. (after at least two hours in supine position).
OR
Upright: Both specimens should be obtained before noon (after at least two hours in upright position, seated or standing).
Contact Medical Director if more information is needed.
Supine: Both specimens should be obtained between 8 a.m. and 10 a.m. (after at least two hours in supine position).
OR
Upright: Both specimens should be obtained before noon (after at least two hours in upright position, seated or standing).
Contact Medical Director if more information is needed.
Specimen Preparation
Separate from cells ASAP or within 2 hours of collection.
Serum: Transfer 1 mL serum to an ARUP Standard Transport Tube. (Min: 0.5 mL)
AND
Plasma: Transfer 2 mL EDTA plasma to an ARUP Standard Transport Tube and freeze immediately. (Min: 1.2 mL)
Serum: Transfer 1 mL serum to an ARUP Standard Transport Tube. (Min: 0.5 mL)
AND
Plasma: Transfer 2 mL EDTA plasma to an ARUP Standard Transport Tube and freeze immediately. (Min: 1.2 mL)
Unacceptable Conditions
Plasma collected in citrate, heparin, or oxalate. Hemolyzed specimens.
Storage/Transport Temperature
NOTE to Outside Clinics/Clients: When submitted spun/aliquotted samples, label the TWO aliquots as SERUM (red/gold/SST) and PLASMA (purple/lav).
Stability (from collection to initiation)
Serum: Ambient: 8 hours; Refrigerated: 5 days; Frozen: 1 month
Plasma: Ambient: 6 hours; Refrigerated: Unacceptable; Frozen: 1 month
Plasma: Ambient: 6 hours; Refrigerated: Unacceptable; Frozen: 1 month
Performed
Sun-Sat
Methodology
Quantitative Chemiluminescent Immunoassay/Quantitative Enzyme-Linked Immunosorbent Assay
Reported
1-5 days
Synonyms
- LAB3919
- A/RA
Ordering Recommendations
Diagnose and screen for primary hyperaldosteronism.
Reference Interval
Components | Reference Interval | ||||||||||||||||||||||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Aldosterone, Serum | Effective May 16, 2011
| ||||||||||||||||||||||||||||||||
Renin Activity |
| ||||||||||||||||||||||||||||||||
Aldosterone/Renin Activity Calculation | Effective May 16, 2011 Less than 25 An Aldosterone/Renin Activity Ratio of greater than 25 is suggestive of hyperaldosteronism if the aldosterone concentration is greater than 15 ng/dL. | ||||||||||||||||||||||||||||||||
CPT Codes
82088; 84244
Collection |
LAB3919
Collect
From either a supine or upright patient, Serum Separator Tube (SST) AND Lavender (EDTA) or Pink (K2EDTA). Do not collect in refrigerated tubes.
Patient Preparation
Normal sodium diet (100-200 mEq/day) for at least three days. Receiving no medications known to affect renin-aldosterone system.
Supine: Both specimens should be obtained between 8 a.m. and 10 a.m. (after at least two hours in supine position).
OR
Upright: Both specimens should be obtained before noon (after at least two hours in upright position, seated or standing).
Contact Medical Director if more information is needed.
Supine: Both specimens should be obtained between 8 a.m. and 10 a.m. (after at least two hours in supine position).
OR
Upright: Both specimens should be obtained before noon (after at least two hours in upright position, seated or standing).
Contact Medical Director if more information is needed.
Specimen Preparation
Separate from cells ASAP or within 2 hours of collection.
Serum: Transfer 1 mL serum to an ARUP Standard Transport Tube. (Min: 0.5 mL)
AND
Plasma: Transfer 2 mL EDTA plasma to an ARUP Standard Transport Tube and freeze immediately. (Min: 1.2 mL)
Serum: Transfer 1 mL serum to an ARUP Standard Transport Tube. (Min: 0.5 mL)
AND
Plasma: Transfer 2 mL EDTA plasma to an ARUP Standard Transport Tube and freeze immediately. (Min: 1.2 mL)
Unacceptable Conditions
Plasma collected in citrate, heparin, or oxalate. Hemolyzed specimens.
Storage/Transport Temperature
NOTE to Outside Clinics/Clients: When submitted spun/aliquotted samples, label the TWO aliquots as SERUM (red/gold/SST) and PLASMA (purple/lav).
Stability (from collection to initiation)
Serum: Ambient: 8 hours; Refrigerated: 5 days; Frozen: 1 month
Plasma: Ambient: 6 hours; Refrigerated: Unacceptable; Frozen: 1 month
Plasma: Ambient: 6 hours; Refrigerated: Unacceptable; Frozen: 1 month
Ordering |
Performed
Sun-Sat
Methodology
Quantitative Chemiluminescent Immunoassay/Quantitative Enzyme-Linked Immunosorbent Assay
Reported
1-5 days
Synonyms
- LAB3919
- A/RA
Ordering Recommendations
Diagnose and screen for primary hyperaldosteronism.
Result Interpretation |
Reference Interval
Components | Reference Interval | ||||||||||||||||||||||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Aldosterone, Serum | Effective May 16, 2011
| ||||||||||||||||||||||||||||||||
Renin Activity |
| ||||||||||||||||||||||||||||||||
Aldosterone/Renin Activity Calculation | Effective May 16, 2011 Less than 25 An Aldosterone/Renin Activity Ratio of greater than 25 is suggestive of hyperaldosteronism if the aldosterone concentration is greater than 15 ng/dL. | ||||||||||||||||||||||||||||||||
Administrative |
CPT Codes
82088; 84244