Tests Catalogs

AFP Tumor Marker

LAB559

AFP MARKER

Collect

5.0 mL, gold or red top with gel (SST), (clot activator serum).

Pediatric Collection

Minimum volume: 3 mL blood

Unacceptable Conditions

Specimen not properly identified; incorrect container; insufficient sample volume.

Storage/Transport Temperature

Internal: Deliver to lab immediately.
Offsite: Separate serum from cells ASAP. Deliver to lab.

Stability (from collection to initiation)

Refrigerated: 24 hours. Frozen: 12 months.

Performed by

PCL Clinical Laboratory - Core

Performed

Upon receipt.

Methodology

Immunoassay - Chemiluminescent

Reported

4 hours after receipt

Synonyms

  • LAB559
  • ALPHA FETOPROTEIN

Reference Interval

0.0-9.0 ng/mL

Performed by

PCL Clinical Laboratory - Core

CPT Codes

82105

Collection

LAB559

AFP MARKER

Collect

5.0 mL, gold or red top with gel (SST), (clot activator serum).

Pediatric Collection

Minimum volume: 3 mL blood

Unacceptable Conditions

Specimen not properly identified; incorrect container; insufficient sample volume.

Storage/Transport Temperature

Internal: Deliver to lab immediately.
Offsite: Separate serum from cells ASAP. Deliver to lab.

Stability (from collection to initiation)

Refrigerated: 24 hours. Frozen: 12 months.

Performed by

PCL Clinical Laboratory - Core

Ordering

Performed

Upon receipt.

Methodology

Immunoassay - Chemiluminescent

Reported

4 hours after receipt

Synonyms

  • LAB559
  • ALPHA FETOPROTEIN
Result Interpretation

Reference Interval

0.0-9.0 ng/mL

Performed by

PCL Clinical Laboratory - Core

Administrative

CPT Codes

82105

AHG CROSSMATCH

Collect

6.0 mL, pink top, plasma (EDTA).

Storage/Transport Temperature

Internal: Deliver to Blood Bank immediatley
Offsite:

Performed by

PCL Clinical Laboratory

Methodology

Hemagglutination (HA).

Performed by

PCL Clinical Laboratory

CPT Codes

86922
Collection

Collect

6.0 mL, pink top, plasma (EDTA).

Storage/Transport Temperature

Internal: Deliver to Blood Bank immediatley
Offsite:

Performed by

PCL Clinical Laboratory
Ordering

Methodology

Hemagglutination (HA).
Result Interpretation

Performed by

PCL Clinical Laboratory
Administrative

CPT Codes

86922

ALANINE

LAB3079

Collect

5.0 mL, gold or red top with gel (SST), (clot activator serum).

Pediatric Collection

0.3 mL

Storage/Transport Temperature

Internal: Deliver to lab immediately at room temperature
Offsite: 0.5 mL plasma/serum. Ship heparinized plasma/serum frozen.

Stability (from collection to initiation)

Frozen

Performed by

UCD Biochemical Genetics Laboratory

Performed

Weekly (Dayshift), day varies

Methodology

Ion Exchange Chromatography

Reported

7 - 10 days

Reference Interval

Premature (first 6 weeks): 212-504

0-1 month: 131-710

1-24 months: 143-439

2-18 years: 152-547

Adult: 177-583

Interpretive Data

Reported in nmol/mL.

Performed by

UCD Biochemical Genetics Laboratory

CPT Codes

82131

Collection

LAB3079

Collect

5.0 mL, gold or red top with gel (SST), (clot activator serum).

Pediatric Collection

0.3 mL

Storage/Transport Temperature

Internal: Deliver to lab immediately at room temperature
Offsite: 0.5 mL plasma/serum. Ship heparinized plasma/serum frozen.

Stability (from collection to initiation)

Frozen

Performed by

UCD Biochemical Genetics Laboratory

Ordering

Performed

Weekly (Dayshift), day varies

Methodology

Ion Exchange Chromatography

Reported

7 - 10 days

Result Interpretation

Reference Interval

Premature (first 6 weeks): 212-504

0-1 month: 131-710

1-24 months: 143-439

2-18 years: 152-547

Adult: 177-583

Interpretive Data

Reported in nmol/mL.

Performed by

UCD Biochemical Genetics Laboratory

Administrative

CPT Codes

82131

ALANINE AMINOTRANSFERASE

LAB132

ALT

Collect

One 4.5 mL green top with gel (PST), (lithium heparin plasma).

Pediatric Collection

At least 0.5 mL blood collected in a microtainer, green top with gel, plasma (lithium heparin), or other heparin tube.

Unacceptable Conditions

Fluoride/oxalate anticoagulant; hemolyzed sample; specimen not properly identified; insufficient sample volume; incorrect container.

Storage/Transport Temperature

Internal: Deliver to lab immediately at ambient temperature.
Offsite: Centrifuge within 30 minutes of collection. Transport to laboratory at 2-8 degrees C.

Stability (from collection to initiation)

Before centrifugation: 1 hour.

After centrifugation: Ambient, 8 hours; Refrigerated, 3 days.

Plasma aliquot: Ambient, 8 hours; Refrigerated, 3 days; Frozen (-20 degrees C), 1 year.

Performed by

PCL Clinical Laboratory - Core

Performed

Upon receipt.

Methodology

Coupled Enzymatic

Reported

Same day

Synonyms

  • SGPT
  • LAB132

Reference Interval

Effective 05/20/2014:

7 - 52 U/L

 

Before 05/20/2014:

Sex From Age To Age Normal Low Normal High Units
M/F 0 1M 0 54 U/L
M/F 1M 15 1 30 U/L
M/F 15 150 0 47 U/L

Interpretive Data

Adult reference range.

Performed by

PCL Clinical Laboratory - Core

CPT Codes

84460

Collection

LAB132

ALT

Collect

One 4.5 mL green top with gel (PST), (lithium heparin plasma).

Pediatric Collection

At least 0.5 mL blood collected in a microtainer, green top with gel, plasma (lithium heparin), or other heparin tube.

Unacceptable Conditions

Fluoride/oxalate anticoagulant; hemolyzed sample; specimen not properly identified; insufficient sample volume; incorrect container.

Storage/Transport Temperature

Internal: Deliver to lab immediately at ambient temperature.
Offsite: Centrifuge within 30 minutes of collection. Transport to laboratory at 2-8 degrees C.

Stability (from collection to initiation)

Before centrifugation: 1 hour.

After centrifugation: Ambient, 8 hours; Refrigerated, 3 days.

Plasma aliquot: Ambient, 8 hours; Refrigerated, 3 days; Frozen (-20 degrees C), 1 year.

Performed by

PCL Clinical Laboratory - Core

Ordering

Performed

Upon receipt.

Methodology

Coupled Enzymatic

Reported

Same day

Synonyms

  • SGPT
  • LAB132
Result Interpretation

Reference Interval

Effective 05/20/2014:

7 - 52 U/L

 

Before 05/20/2014:

Sex From Age To Age Normal Low Normal High Units
M/F 0 1M 0 54 U/L
M/F 1M 15 1 30 U/L
M/F 15 150 0 47 U/L

Interpretive Data

Adult reference range.

Performed by

PCL Clinical Laboratory - Core

Administrative

CPT Codes

84460

ALBUMIN

LAB45

ALBUMIN

 

Collect

One 4.5 mL green top with gel (PST), (lithium heparin plasma).

Pediatric Collection

0.5 mL blood collected in a Greiner green top MiniCollect® tube.

Unacceptable Conditions

EDTA, citrate or oxalate anticoagulants; sample not properly identified; insufficient sample volume.

Storage/Transport Temperature

Internal: Deliver to lab immediately.
Offsite: Centrifuge within 30 minutes of collection, then transport to laboratory at ambient temperature.

Stability (from collection to initiation)

Before centrifugation: 1 hour

After centrifugation: Ambient, 8 hours; Refrigerated, 48 hours

Plasma aliquot: Ambient, 48 hours; Refrigerated, 1 week; Frozen (-20 deg C), 6 months

Performed by

PCL Clinical Laboratory - Core

Performed

Upon receipt

Methodology

Colorimetry Using BCP Dye

Reported

Same day

Synonyms

  • -100
  • LAB45

Reference Interval

Effective 05/20/2014:

From Age To Age Low High Units
0 months 1 month 2.8 4.2 g/dL
1 month 150 yrs 3.5 5.7 g/dL

 

Before 05/20/2014:

Sex From Age To Age Normal Low Normal High Units
M/F 0 1 3.0 5.0 g/dL
M/F 1 150 3.4 5.0 g/dL

Performed by

PCL Clinical Laboratory - Core

CPT Codes

82040

Collection

LAB45

ALBUMIN

 

Collect

One 4.5 mL green top with gel (PST), (lithium heparin plasma).

Pediatric Collection

0.5 mL blood collected in a Greiner green top MiniCollect® tube.

Unacceptable Conditions

EDTA, citrate or oxalate anticoagulants; sample not properly identified; insufficient sample volume.

Storage/Transport Temperature

Internal: Deliver to lab immediately.
Offsite: Centrifuge within 30 minutes of collection, then transport to laboratory at ambient temperature.

Stability (from collection to initiation)

Before centrifugation: 1 hour

After centrifugation: Ambient, 8 hours; Refrigerated, 48 hours

Plasma aliquot: Ambient, 48 hours; Refrigerated, 1 week; Frozen (-20 deg C), 6 months

Performed by

PCL Clinical Laboratory - Core

Ordering

Performed

Upon receipt

Methodology

Colorimetry Using BCP Dye

Reported

Same day

Synonyms

  • -100
  • LAB45
Result Interpretation

Reference Interval

Effective 05/20/2014:

From Age To Age Low High Units
0 months 1 month 2.8 4.2 g/dL
1 month 150 yrs 3.5 5.7 g/dL

 

Before 05/20/2014:

Sex From Age To Age Normal Low Normal High Units
M/F 0 1 3.0 5.0 g/dL
M/F 1 150 3.4 5.0 g/dL

Performed by

PCL Clinical Laboratory - Core

Administrative

CPT Codes

82040

ALBUMIN BODY FLUID

LAB177

ALBUMIN BF

Collect

1 mL fluid in sterile container

Pediatric Collection

Minimum volume: 0.2 mL

Unacceptable Conditions

Sample not properly identified; incorrect container; insufficient sample volume.

Storage/Transport Temperature

Internal: Deliver to lab immediately.
Offsite: Transport to lab at ambient temperature.

Stability (from collection to initiation)

Ambient temperature: 3 days; Refrigerated: 1 week; Frozen: 6 months.

Remarks

Identify fluid source.

Performed by

PCL Clinical Laboratory - Core Laboratory

Performed

Upon receipt.

Methodology

Spectrophotometric

Reported

Same day

Synonyms

  • LAB177

Interpretive Data

The reference range for albumin in body fluids is undefined.  The result must be integrated into the clinical context and/or compared to a synchronous serum or plasma measurement. 
This test was developed and its performance characteristics determined by University of Colorado Hospital.  It has not been cleared or approved by the FDA.  The laboratory is regulated under CLIA as qualified to perform high-complexity testing. This test is used for clinical purposes. It should not be regarded as investigational or for research.

Performed by

PCL Clinical Laboratory - Core Laboratory

CPT Codes

82042

Collection

LAB177

ALBUMIN BF

Collect

1 mL fluid in sterile container

Pediatric Collection

Minimum volume: 0.2 mL

Unacceptable Conditions

Sample not properly identified; incorrect container; insufficient sample volume.

Storage/Transport Temperature

Internal: Deliver to lab immediately.
Offsite: Transport to lab at ambient temperature.

Stability (from collection to initiation)

Ambient temperature: 3 days; Refrigerated: 1 week; Frozen: 6 months.

Remarks

Identify fluid source.

Performed by

PCL Clinical Laboratory - Core Laboratory

Ordering

Performed

Upon receipt.

Methodology

Spectrophotometric

Reported

Same day

Synonyms

  • LAB177
Result Interpretation

Interpretive Data

The reference range for albumin in body fluids is undefined.  The result must be integrated into the clinical context and/or compared to a synchronous serum or plasma measurement. 
This test was developed and its performance characteristics determined by University of Colorado Hospital.  It has not been cleared or approved by the FDA.  The laboratory is regulated under CLIA as qualified to perform high-complexity testing. This test is used for clinical purposes. It should not be regarded as investigational or for research.

Performed by

PCL Clinical Laboratory - Core Laboratory

Administrative

CPT Codes

82042

ALDOLASE

LAB556

Collect

Serum separator tube.

Specimen Preparation

Allow specimen to clot completely at room temperature. Transfer 1 mL serum to an ARUP Standard Transport Tube. (Min: 0.5 mL)

Unacceptable Conditions

Specimen types other than serum. Hemolyzed specimens.

Storage/Transport Temperature

Refrigerated.

Stability (from collection to initiation)

After separation from cells: Ambient: 8 hours; Refrigerated: 5 days; Frozen: 6 months

Performed

Sun-Sat

Methodology

Quantitative Enzymatic

Reported

Within 24 hours

Synonyms

  • LAB556

Ordering Recommendations

Do not use as a stand-alone test. This non-specific test has been replaced by more specific markers for muscle or liver damage. It has largely been replaced by other enzyme tests such as CK, alanine aminotransferase (ALT), and aspartate aminotransferase (AST) as markers of muscle or liver damage.

Reference Interval

0-30 days6.0-32.0 U/L
1-5 months3.0-12.0 U/L
6-35 months3.5-10.0 U/L
3-6 years2.7-8.8 U/L
7-17 years3.3-9.7 U/L
18 years and older1.5-8.1 U/L

CPT Codes

82085
Collection

LAB556

Collect

Serum separator tube.

Specimen Preparation

Allow specimen to clot completely at room temperature. Transfer 1 mL serum to an ARUP Standard Transport Tube. (Min: 0.5 mL)

Unacceptable Conditions

Specimen types other than serum. Hemolyzed specimens.

Storage/Transport Temperature

Refrigerated.

Stability (from collection to initiation)

After separation from cells: Ambient: 8 hours; Refrigerated: 5 days; Frozen: 6 months
Ordering

Performed

Sun-Sat

Methodology

Quantitative Enzymatic

Reported

Within 24 hours

Synonyms

  • LAB556

Ordering Recommendations

Do not use as a stand-alone test. This non-specific test has been replaced by more specific markers for muscle or liver damage. It has largely been replaced by other enzyme tests such as CK, alanine aminotransferase (ALT), and aspartate aminotransferase (AST) as markers of muscle or liver damage.
Result Interpretation

Reference Interval

0-30 days6.0-32.0 U/L
1-5 months3.0-12.0 U/L
6-35 months3.5-10.0 U/L
3-6 years2.7-8.8 U/L
7-17 years3.3-9.7 U/L
18 years and older1.5-8.1 U/L

Administrative

CPT Codes

82085

ALDOSTERONE

LAB557

Collect

Serum separator tube or plain red.

Patient Preparation

If upright specimen is collected, patient should be seated or standing for at least 2 hours.

Specimen Preparation

Transfer 1 mL serum to an ARUP Standard Transport Tube. (Min: 0.5 mL)

Unacceptable Conditions

EDTA plasma.

Storage/Transport Temperature

Frozen.

Stability (from collection to initiation)

After separation from cells: Ambient: 8 hours; Refrigerated: 5 days; Frozen: 1 month

Performed

Sun-Sat

Methodology

Quantitative Chemiluminescent Immunoassay

Reported

Within 24 hours

Synonyms

  • LAB557

Ordering Recommendations

The combined aldosterone/renin tests are preferred (refer to Aldosterone/Renin Activity Ratio (0070073) or Aldosterone and Renin, Direct with Ratio (2002582)) for diagnosing hyperaldosteronism.

Reference Interval

Effective May 16, 2011
Age
Posture Unspecified
Supine
Upright
0-6 days5.0-102.0 ng/dL
1-3 weeks6.0-179.0 ng/dL
1-11 months7.0-99.0 ng/dL
1-2 years7.0-93.0 ng/dL
3-10 years4.0-44.0 ng/dL
11-14 years4.0-31.0 ng/dL
15 years and olderLess than or equal to 31.0 ng/dLLess than or equal to 16.0 ng/dL4.0-31.0 ng/dL

Interpretive Data

Normal serum levels of aldosterone are dependent on the sodium intake and whether the patient is upright or supine. High sodium intake will tend to suppress serum aldosterone, whereas low sodium intake will elevate serum aldosterone. The reference intervals for serum aldosterone are based on normal sodium intake.

CPT Codes

82088
Collection

LAB557

Collect

Serum separator tube or plain red.

Patient Preparation

If upright specimen is collected, patient should be seated or standing for at least 2 hours.

Specimen Preparation

Transfer 1 mL serum to an ARUP Standard Transport Tube. (Min: 0.5 mL)

Unacceptable Conditions

EDTA plasma.

Storage/Transport Temperature

Frozen.

Stability (from collection to initiation)

After separation from cells: Ambient: 8 hours; Refrigerated: 5 days; Frozen: 1 month
Ordering

Performed

Sun-Sat

Methodology

Quantitative Chemiluminescent Immunoassay

Reported

Within 24 hours

Synonyms

  • LAB557

Ordering Recommendations

The combined aldosterone/renin tests are preferred (refer to Aldosterone/Renin Activity Ratio (0070073) or Aldosterone and Renin, Direct with Ratio (2002582)) for diagnosing hyperaldosteronism.
Result Interpretation

Reference Interval

Effective May 16, 2011
Age
Posture Unspecified
Supine
Upright
0-6 days5.0-102.0 ng/dL
1-3 weeks6.0-179.0 ng/dL
1-11 months7.0-99.0 ng/dL
1-2 years7.0-93.0 ng/dL
3-10 years4.0-44.0 ng/dL
11-14 years4.0-31.0 ng/dL
15 years and olderLess than or equal to 31.0 ng/dLLess than or equal to 16.0 ng/dL4.0-31.0 ng/dL

Interpretive Data

Normal serum levels of aldosterone are dependent on the sodium intake and whether the patient is upright or supine. High sodium intake will tend to suppress serum aldosterone, whereas low sodium intake will elevate serum aldosterone. The reference intervals for serum aldosterone are based on normal sodium intake.

Administrative

CPT Codes

82088

ALDOSTERONE URINE

LAB3309

Collect

24-hour urine. Urine must be refrigerated during collection.

Specimen Preparation

Add 1 g boric acid per 100 mL urine. Transfer 4 mL aliquot of urine from a 24-hour collection to an ARUP Standard Transport Tube. (Min: 0.5 mL) Record total volume and collection time interval on transport tube and test request form. Also acceptable: Preserved urine if the pH of the specimen is adjusted to 2-4 with 6M HCl or 50 percent acetic acid or unpreserved urine if frozen immediately after collection.

Storage/Transport Temperature

Frozen. Also acceptable: Refrigerated, if preserved with HCl or acetic acid.

Stability (from collection to initiation)

Ambient: 4 hours; Refrigerated (with preservative): 5 days; Frozen: 1 month

Performed

Tue, Thu, Sat

Methodology

Quantitative Chemiluminescent Immunoassay

Reported

2-5 days

Synonyms

  • LAB3309
  • ALDO U

Ordering Recommendations

For screening and diagnosing for primary hyperaldosteronism, order this urine test concurrently with the serum renin testing (refer to Renin Activity (0070105)).

Reference Interval

Effective October 6, 2014
Components
Reference Interval
Aldosterone, Urine1.2-28.1 µg/d
Creatinine, Urine - per 24h
AgeMaleFemale
3-8 years140-700 mg/d140-700 mg/d
9-12 years300-1300 mg/d300-1300 mg/d
13-17 years500-2300 mg/d400-1600 mg/d
18-50 years1000-2500 mg/d700-1600 mg/d
51-80 years800-2100 mg/d500-1400 mg/d
81 years and older600-2000 mg/d400-1300 mg/d


CPT Codes

82088
Collection

LAB3309

Collect

24-hour urine. Urine must be refrigerated during collection.

Specimen Preparation

Add 1 g boric acid per 100 mL urine. Transfer 4 mL aliquot of urine from a 24-hour collection to an ARUP Standard Transport Tube. (Min: 0.5 mL) Record total volume and collection time interval on transport tube and test request form. Also acceptable: Preserved urine if the pH of the specimen is adjusted to 2-4 with 6M HCl or 50 percent acetic acid or unpreserved urine if frozen immediately after collection.

Storage/Transport Temperature

Frozen. Also acceptable: Refrigerated, if preserved with HCl or acetic acid.

Stability (from collection to initiation)

Ambient: 4 hours; Refrigerated (with preservative): 5 days; Frozen: 1 month
Ordering

Performed

Tue, Thu, Sat

Methodology

Quantitative Chemiluminescent Immunoassay

Reported

2-5 days

Synonyms

  • LAB3309
  • ALDO U

Ordering Recommendations

For screening and diagnosing for primary hyperaldosteronism, order this urine test concurrently with the serum renin testing (refer to Renin Activity (0070105)).
Result Interpretation

Reference Interval

Effective October 6, 2014
Components
Reference Interval
Aldosterone, Urine1.2-28.1 µg/d
Creatinine, Urine - per 24h
AgeMaleFemale
3-8 years140-700 mg/d140-700 mg/d
9-12 years300-1300 mg/d300-1300 mg/d
13-17 years500-2300 mg/d400-1600 mg/d
18-50 years1000-2500 mg/d700-1600 mg/d
51-80 years800-2100 mg/d500-1400 mg/d
81 years and older600-2000 mg/d400-1300 mg/d


Administrative

CPT Codes

82088

Aldosterone/Renin Activity Ratio

LAB3919

Collect

From either a supine or upright patient, Serum Separator Tube (SST) AND Lavender (EDTA) or Pink (K2EDTA). Do not collect in refrigerated tubes.

Patient Preparation

Normal sodium diet (100-200 mEq/day) for at least three days. Receiving no medications known to affect renin-aldosterone system.
Supine: Both specimens should be obtained between 8 a.m. and 10 a.m. (after at least two hours in supine position).
OR
Upright: Both specimens should be obtained before noon (after at least two hours in upright position, seated or standing).
Contact Medical Director if more information is needed.

Specimen Preparation

Separate from cells ASAP or within 2 hours of collection.
Serum: Transfer 1 mL serum to an ARUP Standard Transport Tube. (Min: 0.5 mL)
AND 
Plasma: Transfer 2 mL EDTA plasma to an ARUP Standard Transport Tube and freeze immediately. (Min: 1.2 mL)

Unacceptable Conditions

Plasma collected in citrate, heparin, or oxalate. Hemolyzed specimens.

Storage/Transport Temperature

Both specimens should be submitted together for testing.
Serum: Frozen. Also acceptable: Refrigerated.
Plasma: CRITICAL FROZEN.  Separate specimens must be submitted when additional tests are ordered.

Stability (from collection to initiation)

Serum: Ambient: 8 hours; Refrigerated: 5 days; Frozen: 1 month
Plasma: Ambient: 6 hours; Refrigerated: Unacceptable; Frozen: 1 month

Performed

Sun-Sat

Methodology

Quantitative Chemiluminescent Immunoassay/Quantitative Enzyme-Linked Immunosorbent Assay

Reported

1-5 days

Synonyms

  • ARR
  • Aldosterone and Plasma Renin Activity
  • Aldosterone serum
  • Renin Activity
  • PRA
  • ARR-P
  • Aldosterone/Renin Activity
  • A/RA
  • LAB3919

Ordering Recommendations

Diagnose and screen for primary hyperaldosteronism.

Reference Interval

Components
Reference Interval
Aldosterone, SerumEffective May 16, 2011
Age
Posture Unspecified
Supine
Upright
0-6 days5.0-102.0 ng/dL
1-3 weeks6.0-179.0 ng/dL
1-11 months7.0-99.0 ng/dL
1-2 years7.0-93.0 ng/dL
3-10 years4.0-44.0 ng/dL
11-14 years4.0-31.0 ng/dL
15 years and olderLess than or equal to 31.0 ng/dLLess than or equal to 16.0 ng/dL4.0-31.0 ng/dL

Renin Activity
Adult, normal sodium diet
Children, normal sodium diet, supine:
Children, normal sodium diet, upright:
Supine: 0.2-1.6 ng/mL/hrNewborn (1-7 days): 2.0-35.0 ng/mL/hr0-3 years: Not Available
Upright: 0.5-4.0 ng/mL/hrCord blood: 4.0-32.0 ng/mL/hr4-5 years: Less than or equal to 15 ng/mL/hr
1-12 months: 2.4-37.0 ng/mL/hr6-10 years: Less than or equal to 17 ng/mL/hr
13 months-3 years:1.7-11.2 ng/mL/hr11-15 years: Less than or equal to 16 ng/mL/hr
4-5 years:1.0-6.5 ng/mL/hr
6-10 years: 0.5-5.9 ng/mL/hr
11-15 years: 0.5-3.3 ng/mL/hr

Aldosterone/Renin Activity CalculationEffective May 16, 2011

Less than 25
An Aldosterone/Renin Activity Ratio of greater than 25 is suggestive of hyperaldosteronism if the aldosterone concentration is greater than 15 ng/dL.


CPT Codes

82088; 84244
Collection

LAB3919

Collect

From either a supine or upright patient, Serum Separator Tube (SST) AND Lavender (EDTA) or Pink (K2EDTA). Do not collect in refrigerated tubes.

Patient Preparation

Normal sodium diet (100-200 mEq/day) for at least three days. Receiving no medications known to affect renin-aldosterone system.
Supine: Both specimens should be obtained between 8 a.m. and 10 a.m. (after at least two hours in supine position).
OR
Upright: Both specimens should be obtained before noon (after at least two hours in upright position, seated or standing).
Contact Medical Director if more information is needed.

Specimen Preparation

Separate from cells ASAP or within 2 hours of collection.
Serum: Transfer 1 mL serum to an ARUP Standard Transport Tube. (Min: 0.5 mL)
AND 
Plasma: Transfer 2 mL EDTA plasma to an ARUP Standard Transport Tube and freeze immediately. (Min: 1.2 mL)

Unacceptable Conditions

Plasma collected in citrate, heparin, or oxalate. Hemolyzed specimens.

Storage/Transport Temperature

Both specimens should be submitted together for testing.
Serum: Frozen. Also acceptable: Refrigerated.
Plasma: CRITICAL FROZEN.  Separate specimens must be submitted when additional tests are ordered.

Stability (from collection to initiation)

Serum: Ambient: 8 hours; Refrigerated: 5 days; Frozen: 1 month
Plasma: Ambient: 6 hours; Refrigerated: Unacceptable; Frozen: 1 month
Ordering

Performed

Sun-Sat

Methodology

Quantitative Chemiluminescent Immunoassay/Quantitative Enzyme-Linked Immunosorbent Assay

Reported

1-5 days

Synonyms

  • ARR
  • Aldosterone and Plasma Renin Activity
  • Aldosterone serum
  • Renin Activity
  • PRA
  • ARR-P
  • Aldosterone/Renin Activity
  • A/RA
  • LAB3919

Ordering Recommendations

Diagnose and screen for primary hyperaldosteronism.
Result Interpretation

Reference Interval

Components
Reference Interval
Aldosterone, SerumEffective May 16, 2011
Age
Posture Unspecified
Supine
Upright
0-6 days5.0-102.0 ng/dL
1-3 weeks6.0-179.0 ng/dL
1-11 months7.0-99.0 ng/dL
1-2 years7.0-93.0 ng/dL
3-10 years4.0-44.0 ng/dL
11-14 years4.0-31.0 ng/dL
15 years and olderLess than or equal to 31.0 ng/dLLess than or equal to 16.0 ng/dL4.0-31.0 ng/dL

Renin Activity
Adult, normal sodium diet
Children, normal sodium diet, supine:
Children, normal sodium diet, upright:
Supine: 0.2-1.6 ng/mL/hrNewborn (1-7 days): 2.0-35.0 ng/mL/hr0-3 years: Not Available
Upright: 0.5-4.0 ng/mL/hrCord blood: 4.0-32.0 ng/mL/hr4-5 years: Less than or equal to 15 ng/mL/hr
1-12 months: 2.4-37.0 ng/mL/hr6-10 years: Less than or equal to 17 ng/mL/hr
13 months-3 years:1.7-11.2 ng/mL/hr11-15 years: Less than or equal to 16 ng/mL/hr
4-5 years:1.0-6.5 ng/mL/hr
6-10 years: 0.5-5.9 ng/mL/hr
11-15 years: 0.5-3.3 ng/mL/hr

Aldosterone/Renin Activity CalculationEffective May 16, 2011

Less than 25
An Aldosterone/Renin Activity Ratio of greater than 25 is suggestive of hyperaldosteronism if the aldosterone concentration is greater than 15 ng/dL.


Administrative

CPT Codes

82088; 84244

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