SERINE PROTEASE 3 AB

LAB3114

 

Collect

One 7 ml red top with gel

Unacceptable Conditions

Excessive hemolysis, chylous serum, gross contamination, inadequate volume of blood, inadequate patient and/or specimen identification.

Storage/Transport Temperature

Internal: Deliver to lab immediately
Offsite: 2 mL Separate serum from cells and deliver to the lab refrigerated.

Stability (from collection to initiation)

Refrigerated: 1-2 weeks; Frozen: Indefinitely.

Remarks

PR3AB are recomended after the PANCA and CANCA have been tested on immunofluorescence.

Performed by

PCL Clinical Laboratory

Performed

Mon - Fri

Methodology

Enzyme-linked immunosorbent assay [ELISA].

Reported

In 14 days

Synonyms

  • LAB3114

Reference Interval

0-20 units

Interpretive Data

INTERPRETATION:

0-20 units = NEGATIVE [Normal]
21-30 units = WEAK POSITIVE

>30 units = MODERATE-STRONG POSITIVE

Performed by

PCL Clinical Laboratory

CPT Codes

83520

Collection

LAB3114

 

Collect

One 7 ml red top with gel

Unacceptable Conditions

Excessive hemolysis, chylous serum, gross contamination, inadequate volume of blood, inadequate patient and/or specimen identification.

Storage/Transport Temperature

Internal: Deliver to lab immediately
Offsite: 2 mL Separate serum from cells and deliver to the lab refrigerated.

Stability (from collection to initiation)

Refrigerated: 1-2 weeks; Frozen: Indefinitely.

Remarks

PR3AB are recomended after the PANCA and CANCA have been tested on immunofluorescence.

Performed by

PCL Clinical Laboratory

Ordering

Performed

Mon - Fri

Methodology

Enzyme-linked immunosorbent assay [ELISA].

Reported

In 14 days

Synonyms

  • LAB3114
Result Interpretation

Reference Interval

0-20 units

Interpretive Data

INTERPRETATION:

0-20 units = NEGATIVE [Normal]
21-30 units = WEAK POSITIVE

>30 units = MODERATE-STRONG POSITIVE

Performed by

PCL Clinical Laboratory

Administrative

CPT Codes

83520

SEROTONIN

LAB121

 

Collect

Serum separator tube.

Patient Preparation

Abstain from medications for 72 hours prior to collection.

Specimen Preparation

Spin and separate within one hour. Transfer 1 mL serum to an ARUP Standard Transport Tube. (Min: 0.3 mL)

Unacceptable Conditions

Specimens other than serum. Non-frozen specimens.

Storage/Transport Temperature

Frozen.

Stability (from collection to initiation)

After separation from cells: Ambient: Unacceptable; Refrigerated: 24 hours; Frozen: 1 month

Notes

Medications that may affect serotonin concentrations include lithium, MAO inhibitors, methyldopa, morphine, and reserpine.  In general, foods that contain serotonin do not interfere significantly.  Slight increases may be seen in acute intestinal obstruction, acute MI, cystic fibrosis, dumping syndromes, and nontropical sprue.  Metastasizing abdominal carcinoid tumors often show serotonin concentrations greater than 400 ng/mL.

In general, EDTA whole blood (as compared to serum) preserved with ascorbic acid will give values most representative of blood concentrations. Most (95 percent) of blood serotonin is found in platelets. Refer to Serotonin, Whole Blood (ARUP test code 0080395).

Performed

Sun, Tue-Fri

Methodology

Quantitative High Performance Liquid Chromatography

Reported

1-5 days

Synonyms

  • 5-Hydroxytryptamine, Serum
  • 5-HT, Serum
  • LAB121

Ordering Recommendations

Preferred serotonin test when diagnosing carcinoid tumors is Serotonin, Whole Blood (0080395).

Reference Interval

50-220 ng/mL

CPT Codes

84260
Collection

LAB121

 

Collect

Serum separator tube.

Patient Preparation

Abstain from medications for 72 hours prior to collection.

Specimen Preparation

Spin and separate within one hour. Transfer 1 mL serum to an ARUP Standard Transport Tube. (Min: 0.3 mL)

Unacceptable Conditions

Specimens other than serum. Non-frozen specimens.

Storage/Transport Temperature

Frozen.

Stability (from collection to initiation)

After separation from cells: Ambient: Unacceptable; Refrigerated: 24 hours; Frozen: 1 month

Notes

Medications that may affect serotonin concentrations include lithium, MAO inhibitors, methyldopa, morphine, and reserpine.  In general, foods that contain serotonin do not interfere significantly.  Slight increases may be seen in acute intestinal obstruction, acute MI, cystic fibrosis, dumping syndromes, and nontropical sprue.  Metastasizing abdominal carcinoid tumors often show serotonin concentrations greater than 400 ng/mL.

In general, EDTA whole blood (as compared to serum) preserved with ascorbic acid will give values most representative of blood concentrations. Most (95 percent) of blood serotonin is found in platelets. Refer to Serotonin, Whole Blood (ARUP test code 0080395).
Ordering

Performed

Sun, Tue-Fri

Methodology

Quantitative High Performance Liquid Chromatography

Reported

1-5 days

Synonyms

  • 5-Hydroxytryptamine, Serum
  • 5-HT, Serum
  • LAB121

Ordering Recommendations

Preferred serotonin test when diagnosing carcinoid tumors is Serotonin, Whole Blood (0080395).
Result Interpretation

Reference Interval

50-220 ng/mL
Administrative

CPT Codes

84260

SEROTONIN RELEASE ASSAY (SRA)

LAB3536

Collect

Serum separator tube.

Specimen Preparation

Transfer 5 mL serum to ARUP Standard Transport Tubes. (Min: 1 mL)

Storage/Transport Temperature

Frozen. Also acceptable: Refrigerated.

Stability (from collection to initiation)

Ambient: Unacceptable; Refrigerated: 1 week; Frozen: Indefinite

Performed

Mon-Sat

Methodology

Qualitative Serotonin Release Assay

Reported

2-4 days

Synonyms

  • LAB3536
  • SRA UFH

Ordering Recommendations

Gold standard test for diagnosis of heparin-induced thrombocytopenia (HIT).

Reference Interval

By report

CPT Codes

86022
Collection

LAB3536

Collect

Serum separator tube.

Specimen Preparation

Transfer 5 mL serum to ARUP Standard Transport Tubes. (Min: 1 mL)

Storage/Transport Temperature

Frozen. Also acceptable: Refrigerated.

Stability (from collection to initiation)

Ambient: Unacceptable; Refrigerated: 1 week; Frozen: Indefinite
Ordering

Performed

Mon-Sat

Methodology

Qualitative Serotonin Release Assay

Reported

2-4 days

Synonyms

  • LAB3536
  • SRA UFH

Ordering Recommendations

Gold standard test for diagnosis of heparin-induced thrombocytopenia (HIT).
Result Interpretation

Reference Interval

By report
Administrative

CPT Codes

86022