Tests Catalogs

STREPTOZYME SCREEN/RFLX TITER

LAB1193

Collect

Serum separator tube, lavender (EDTA), or pink (K2EDTA).

Specimen Preparation

Separate serum or plasma from cells ASAP or within 2 hours of collection. Transfer 1 mL serum or plasma to an ARUP Standard Transport Tube. (Min: 0.05 mL)

Storage/Transport Temperature

Refrigerated.

Stability (from collection to initiation)

After separation from cells: Ambient: 48 hours; Refrigerated: 2 weeks; Frozen: 1 year (avoid repeated freeze/thaw cycles)

Notes

If S. pyogenes Ab is detected, then titer will be added. Additional charges apply

Performed

Mon, Wed, Fri

Methodology

Semi-Quantitative Hemagglutination

Reported

1-4 days

Synonyms

  • Streptozyme{R}
  • LAB1193
  • STZ R

Ordering Recommendations

Outdated test. Recommend DNase-B antibody and/or Streptolysin O antibody tests.

Reference Interval

Effective February 17, 2015
Components
Reference Interval
Streptozyme ScreenNone Detected
Streptozyme Titer< 1:100: Negative

CPT Codes

86403; if reflexed, add 86406
Collection

LAB1193

Collect

Serum separator tube, lavender (EDTA), or pink (K2EDTA).

Specimen Preparation

Separate serum or plasma from cells ASAP or within 2 hours of collection. Transfer 1 mL serum or plasma to an ARUP Standard Transport Tube. (Min: 0.05 mL)

Storage/Transport Temperature

Refrigerated.

Stability (from collection to initiation)

After separation from cells: Ambient: 48 hours; Refrigerated: 2 weeks; Frozen: 1 year (avoid repeated freeze/thaw cycles)

Notes

If S. pyogenes Ab is detected, then titer will be added. Additional charges apply
Ordering

Performed

Mon, Wed, Fri

Methodology

Semi-Quantitative Hemagglutination

Reported

1-4 days

Synonyms

  • Streptozyme{R}
  • LAB1193
  • STZ R

Ordering Recommendations

Outdated test. Recommend DNase-B antibody and/or Streptolysin O antibody tests.
Result Interpretation

Reference Interval

Effective February 17, 2015
Components
Reference Interval
Streptozyme ScreenNone Detected
Streptozyme Titer< 1:100: Negative

Administrative

CPT Codes

86403; if reflexed, add 86406

STRIATIONAL (STRIATED MUSCLE) ANTIBODY - IGG

LAB3721

Collect

Serum separator tube.

Specimen Preparation

Separate serum from cells ASAP or within 2 hours of collection. Transfer 1 mL serum to an ARUP Standard Transport Tube. (Min: 0.15 mL)

Unacceptable Conditions

Plasma. Contaminated, hemolyzed, or severely lipemic specimens.

Storage/Transport Temperature

Refrigerated.

Stability (from collection to initiation)

After separation from cells: Ambient: 48 hours; Refrigerated: 2 weeks; Frozen: 1 year (avoid repeated freeze/thaw cycles)

Notes

If Striated Muscle Abs detected, a titer will be added. Additional charges apply.

Performed

Mon-Fri

Methodology

Semi-Quantitative Indirect Fluorescent Antibody

Reported

1-5 days

Synonyms

  • Anti-Striated Muscle Antibody
  • Anti-Striational Antibody
  • Striated Muscle Antibody - IgG
  • LAB3721
  • STM R

Additional Technical Information

Ordering Recommendations

Recommended for differential evaluation of neuromuscular junction diseases including myasthenia gravis (MG).

Reference Interval

Less than 1:40

Interpretive Data

When detected in the presence of acetylcholine receptor (AChR) antibody, striated muscle antibodies, which bind in a cross-striational pattern to skeletal and heart muscle tissue sections, are associated with late-onset myasthenia gravis (MG). Striated muscle antibodies recognize epitopes on three major muscle proteins, including: titin, ryanodine receptor (RyR) and Kv1.4 (an alpha subunit of voltage-gated potassium channel [VGKC]). Isolated cases of striated muscle antibodies may be seen in patients with certain autoimmune diseases, rheumatic fever, myocardial infarction, and following some cardiotomy procedures.

CPT Codes

86255; if reflexed, add 86256
Collection

LAB3721

Collect

Serum separator tube.

Specimen Preparation

Separate serum from cells ASAP or within 2 hours of collection. Transfer 1 mL serum to an ARUP Standard Transport Tube. (Min: 0.15 mL)

Unacceptable Conditions

Plasma. Contaminated, hemolyzed, or severely lipemic specimens.

Storage/Transport Temperature

Refrigerated.

Stability (from collection to initiation)

After separation from cells: Ambient: 48 hours; Refrigerated: 2 weeks; Frozen: 1 year (avoid repeated freeze/thaw cycles)

Notes

If Striated Muscle Abs detected, a titer will be added. Additional charges apply.
Ordering

Performed

Mon-Fri

Methodology

Semi-Quantitative Indirect Fluorescent Antibody

Reported

1-5 days

Synonyms

  • Anti-Striated Muscle Antibody
  • Anti-Striational Antibody
  • Striated Muscle Antibody - IgG
  • LAB3721
  • STM R

Additional Technical Information

Ordering Recommendations

Recommended for differential evaluation of neuromuscular junction diseases including myasthenia gravis (MG).
Result Interpretation

Reference Interval

Less than 1:40

Interpretive Data

When detected in the presence of acetylcholine receptor (AChR) antibody, striated muscle antibodies, which bind in a cross-striational pattern to skeletal and heart muscle tissue sections, are associated with late-onset myasthenia gravis (MG). Striated muscle antibodies recognize epitopes on three major muscle proteins, including: titin, ryanodine receptor (RyR) and Kv1.4 (an alpha subunit of voltage-gated potassium channel [VGKC]). Isolated cases of striated muscle antibodies may be seen in patients with certain autoimmune diseases, rheumatic fever, myocardial infarction, and following some cardiotomy procedures.

Administrative

CPT Codes

86255; if reflexed, add 86256

SUCCINYLACETONE URINE

LAB3298

Collect

2 mL random urine frozen. Transpot to lab on dry ice.

Pediatric Collection

0.3 mL

Storage/Transport Temperature

Internal: Deliver to lab immediately at room temperature
Offsite: 2 mL random urine specimen Deliver to the lab refrigerated or frozen.

Performed by

Children's Hospital Colorado Biochemical Genetics Laboratory

Performed

Weekly (Dayshift), day varies

Reported

7 - 10 days

Synonyms

  • LAB3298

Performed by

Children's Hospital Colorado Biochemical Genetics Laboratory

CPT Codes

82543

Collection

LAB3298

Collect

2 mL random urine frozen. Transpot to lab on dry ice.

Pediatric Collection

0.3 mL

Storage/Transport Temperature

Internal: Deliver to lab immediately at room temperature
Offsite: 2 mL random urine specimen Deliver to the lab refrigerated or frozen.

Performed by

Children's Hospital Colorado Biochemical Genetics Laboratory

Ordering

Performed

Weekly (Dayshift), day varies

Reported

7 - 10 days

Synonyms

  • LAB3298
Result Interpretation

Performed by

Children's Hospital Colorado Biochemical Genetics Laboratory

Administrative

CPT Codes

82543

SUCCINYLPURINE URINE

LAB3299

Collect

10 mL Random urine 1 mL CSF

Pediatric Collection

0.3 mL

Unacceptable Conditions

Ambient samples.

Storage/Transport Temperature

Internal: Deliver to lab immediately at room temperature
Offsite: 2 mL random urine specimen Deliver to the lab refrigerated or frozen.

Stability (from collection to initiation)

Frozen.

Remarks

.

Performed by

Children's Hospital Colorado Biochemical Genetics Laboratory

Performed

Weekly (Dayshift), day varies

Methodology

Bratton-Marshall Reaction [Diazo reaction]

Reported

3 - 10 days

Synonyms

  • LAB3299

Performed by

Children's Hospital Colorado Biochemical Genetics Laboratory

CPT Codes

84311

Collection

LAB3299

Collect

10 mL Random urine 1 mL CSF

Pediatric Collection

0.3 mL

Unacceptable Conditions

Ambient samples.

Storage/Transport Temperature

Internal: Deliver to lab immediately at room temperature
Offsite: 2 mL random urine specimen Deliver to the lab refrigerated or frozen.

Stability (from collection to initiation)

Frozen.

Remarks

.

Performed by

Children's Hospital Colorado Biochemical Genetics Laboratory

Ordering

Performed

Weekly (Dayshift), day varies

Methodology

Bratton-Marshall Reaction [Diazo reaction]

Reported

3 - 10 days

Synonyms

  • LAB3299
Result Interpretation

Performed by

Children's Hospital Colorado Biochemical Genetics Laboratory

Administrative

CPT Codes

84311

SULFA DRUGS - LIST DRUG

Collect

Plain red. Also acceptable: Lavender (K2 or K3EDTA) or pink (K2EDTA).

Patient Preparation

Timing of specimen collection: Peak draw.

Specimen Preparation

Separate serum or plasma from cells within 2 hours of collection. Transfer 1 mL serum or plasma to an ARUP Standard Transport Tube. (Min: 0.5 mL)

Unacceptable Conditions

Whole blood. Gel separator tubes, light blue (citrate), or yellow (SPS or ACD solution).

Storage/Transport Temperature

Refrigerated.

Stability (from collection to initiation)

After separation from cells: Ambient: 2 weeks; Refrigerated: 2 weeks; Frozen: 2 weeks

Remarks

Indicate which sulfa drug is being administered.

Performed

Tue, Fri

Methodology

Quantitative Colorimetry

Reported

1-5 days

Synonyms

  • Septra
  • Sulfa Drugs
  • Bactrim
  • Gantricin

Ordering Recommendations

Optimize drug therapy and monitor patient adherence.

Reference Interval

Therapeutic Range:
5.0-15.0 mg/dL
Toxic: > 20.0 mg/dL

Interpretive Data

 This test is designed to measure sulfamethoxazole and sulfisoxazole. Peak sulfonamide (total) blood levels of 5.0-15.0 mg/dL may be effective for most infections, with concentrations of 12.0-15.0 mg/dL being optimal for serious infections. Sulfonamide levels should not exceed 20.0 mg/dL. Adverse effects may include blood dyscrasias, skin rash, nausea, vomiting and fever.

CPT Codes

80299
Collection

Collect

Plain red. Also acceptable: Lavender (K2 or K3EDTA) or pink (K2EDTA).

Patient Preparation

Timing of specimen collection: Peak draw.

Specimen Preparation

Separate serum or plasma from cells within 2 hours of collection. Transfer 1 mL serum or plasma to an ARUP Standard Transport Tube. (Min: 0.5 mL)

Unacceptable Conditions

Whole blood. Gel separator tubes, light blue (citrate), or yellow (SPS or ACD solution).

Storage/Transport Temperature

Refrigerated.

Stability (from collection to initiation)

After separation from cells: Ambient: 2 weeks; Refrigerated: 2 weeks; Frozen: 2 weeks

Remarks

Indicate which sulfa drug is being administered.
Ordering

Performed

Tue, Fri

Methodology

Quantitative Colorimetry

Reported

1-5 days

Synonyms

  • Septra
  • Sulfa Drugs
  • Bactrim
  • Gantricin

Ordering Recommendations

Optimize drug therapy and monitor patient adherence.
Result Interpretation

Reference Interval

Therapeutic Range:
5.0-15.0 mg/dL
Toxic: > 20.0 mg/dL

Interpretive Data

 This test is designed to measure sulfamethoxazole and sulfisoxazole. Peak sulfonamide (total) blood levels of 5.0-15.0 mg/dL may be effective for most infections, with concentrations of 12.0-15.0 mg/dL being optimal for serious infections. Sulfonamide levels should not exceed 20.0 mg/dL. Adverse effects may include blood dyscrasias, skin rash, nausea, vomiting and fever.

Administrative

CPT Codes

80299

SULFATE3GLUC PARAGLOBOSIDE IGM

LAB3155

Collect

Serum separator tube.

Specimen Preparation

Separate serum from cells ASAP or within 2 hours of collection. Transfer 1 mL serum to an ARUP Standard Transport Tube. (Min: 0.1 mL)

Unacceptable Conditions

Plasma or urine. Contaminated, heat-inactivated, hemolyzed, icteric, or severely lipemic specimens.

Storage/Transport Temperature

Refrigerated.

Stability (from collection to initiation)

After separation from cells: Ambient: 48 hours; Refrigerated: 2 weeks; Frozen: 1 year

Performed

Tues.

Methodology

Semi-Quantitative Enzyme-Linked Immunosorbent Assay

Reported

1-8 days

Synonyms

  • SGPG Antibody, IgM
  • LAB3155

Additional Technical Information

Ordering Recommendations

Non-panel testing for autoimmune neuropathies. Test by itself is not diagnostic and should be used in conjunction with other clinical parameters to confirm disease.

Reference Interval

Less than 1.00 IV

Interpretive Data

The majority of SGPG IgM positive sera will show reactivity against MAG.  Patients that are SGPG IgM positive and MAG IgM negative may have multi-focal motor neuropathy with conduction block.

CPT Codes

83516
Collection

LAB3155

Collect

Serum separator tube.

Specimen Preparation

Separate serum from cells ASAP or within 2 hours of collection. Transfer 1 mL serum to an ARUP Standard Transport Tube. (Min: 0.1 mL)

Unacceptable Conditions

Plasma or urine. Contaminated, heat-inactivated, hemolyzed, icteric, or severely lipemic specimens.

Storage/Transport Temperature

Refrigerated.

Stability (from collection to initiation)

After separation from cells: Ambient: 48 hours; Refrigerated: 2 weeks; Frozen: 1 year
Ordering

Performed

Tues.

Methodology

Semi-Quantitative Enzyme-Linked Immunosorbent Assay

Reported

1-8 days

Synonyms

  • SGPG Antibody, IgM
  • LAB3155

Additional Technical Information

Ordering Recommendations

Non-panel testing for autoimmune neuropathies. Test by itself is not diagnostic and should be used in conjunction with other clinical parameters to confirm disease.
Result Interpretation

Reference Interval

Less than 1.00 IV

Interpretive Data

The majority of SGPG IgM positive sera will show reactivity against MAG.  Patients that are SGPG IgM positive and MAG IgM negative may have multi-focal motor neuropathy with conduction block.

Administrative

CPT Codes

83516

SULFONYLUREA HYPOGLYCEMICS PANEL

LAB3583

Collect

Plain red, gray (NaF/K Oxalate), green (Na Heparin), lavender (EDTA), or pink (K2EDTA).

Specimen Preparation

Separate from cells ASAP or within 2 hours of collection. Transfer 1 mL serum or plasma to an ARUP Standard Transport Tube. (Min: 0.4 mL)

Unacceptable Conditions

Separator tubes.

Storage/Transport Temperature

Frozen. Also acceptable: Refrigerated.

Stability (from collection to initiation)

Ambient: 48 hours; Refrigerated: 11 days; Frozen: 3 months

Performed

Wed, Sun

Methodology

Qualitative Liquid Chromatography-Tandem Mass Spectrometry

Reported

1-6 days

Synonyms

  • MEGLITINIDES
  • LAB3583
  • Diabinese{R} (Sulfonylurea Hypoglycemics Panel (Qualitative), Serum or Plasma)
  • SULFON
  • HYPOGLYCEM

Additional Technical Information

Ordering Recommendations

Preferred test for evaluating if etiology of hypoglycemia is sulfonylurea ingestion.

Reference Interval

DrugCutoff Concentration
Glyburide5 ng/mL
Glimepiride5 ng/mL
Glipizide5 ng/mL
Repaglinide5 ng/mL
Nateglinide5 ng/mL
Acetohexamide100 ng/mL
Chlorpropamide100 ng/mL
Tolazamide100 ng/mL
Tolbutamide100 ng/mL

Interpretive Data

This assay is used to evaluate hypoglycemia that may be caused from the ingestion of sulfonylurea drugs. Hypoglycemic drugs are detected (present) in this assay if the drug concentration is greater than the limit of detection (cut-off). The presence of hypoglycemic drug(s) indicates a recent ingestion.

CPT Codes

80377 (Alt code: G0480)
Collection

LAB3583

Collect

Plain red, gray (NaF/K Oxalate), green (Na Heparin), lavender (EDTA), or pink (K2EDTA).

Specimen Preparation

Separate from cells ASAP or within 2 hours of collection. Transfer 1 mL serum or plasma to an ARUP Standard Transport Tube. (Min: 0.4 mL)

Unacceptable Conditions

Separator tubes.

Storage/Transport Temperature

Frozen. Also acceptable: Refrigerated.

Stability (from collection to initiation)

Ambient: 48 hours; Refrigerated: 11 days; Frozen: 3 months
Ordering

Performed

Wed, Sun

Methodology

Qualitative Liquid Chromatography-Tandem Mass Spectrometry

Reported

1-6 days

Synonyms

  • MEGLITINIDES
  • LAB3583
  • Diabinese{R} (Sulfonylurea Hypoglycemics Panel (Qualitative), Serum or Plasma)
  • SULFON
  • HYPOGLYCEM

Additional Technical Information

Ordering Recommendations

Preferred test for evaluating if etiology of hypoglycemia is sulfonylurea ingestion.
Result Interpretation

Reference Interval

DrugCutoff Concentration
Glyburide5 ng/mL
Glimepiride5 ng/mL
Glipizide5 ng/mL
Repaglinide5 ng/mL
Nateglinide5 ng/mL
Acetohexamide100 ng/mL
Chlorpropamide100 ng/mL
Tolazamide100 ng/mL
Tolbutamide100 ng/mL

Interpretive Data

This assay is used to evaluate hypoglycemia that may be caused from the ingestion of sulfonylurea drugs. Hypoglycemic drugs are detected (present) in this assay if the drug concentration is greater than the limit of detection (cut-off). The presence of hypoglycemic drug(s) indicates a recent ingestion.

Administrative

CPT Codes

80377 (Alt code: G0480)

SACCHAROMYCES CEREVISIAE ABS

LAB548

 

Collect

Serum separator tube.

Specimen Preparation

Separate serum from cells ASAP or within 2 hours of collection. Transfer 0.5 mL serum to an ARUP Standard Transport Tube. (Min: 0.3 mL)

Unacceptable Conditions

Contaminated, heat-inactivated, hemolyzed, or severely lipemic specimens.

Storage/Transport Temperature

Refrigerated.

Stability (from collection to initiation)

After separation from cells: Ambient: 48 hours; Refrigerated: 2 weeks; Frozen: 1 year (avoid repeated freeze/thaw cycles)

Notes

This test may be a useful tool for distinguishing ulcerative colitis (UC) from Crohn disease (CD) in patients with suspected inflammatory bowel disease.

Performed

Sun-Sat

Methodology

Semi-Quantitative Enzyme-Linked Immunosorbent Assay

Reported

1-2 days

Synonyms

  • SACC CEREVISIAE ABS
  • ASCA IGG/IGA
  • S CEREVISIAE ABS
  • SACCHAROMYCES AB
  • LAB548

Ordering Recommendations

May be useful for the diagnosis of Crohn disease. Test by itself is not diagnostic and should be used in conjunction with other parameters to confirm disease. Inflammatory Bowel Disease Differentiation Panel (2013270) is the preferred test.

Reference Interval

Components
Reference Interval
S. cerevisiae Antibody, IgG20.0 Units or less: Negative
20.1-24.9 Units: Equivocal
25.0 Units or greater: Positive
S. cerevisiae Antibody, IgA20.0 Units or less: Negative
20.1-24.9 Units: Equivocal
25.0 Units or greater: Positive

Interpretive Data

Saccharomyces cerevisiae IgG antibodies are found in 60-70% of Crohn disease (CD) patients and 10-15% of ulcerative colitis (UC) patients. Saccharomyces cerevisiae IgA antibodies are found in about 35% of CD patients but less than 1% in UC patients. Detection of both Saccharomyces IgG and IgA antibodies in the same serum specimen is highly specific for CD.

CPT Codes

86671 x2
Collection

LAB548

 

Collect

Serum separator tube.

Specimen Preparation

Separate serum from cells ASAP or within 2 hours of collection. Transfer 0.5 mL serum to an ARUP Standard Transport Tube. (Min: 0.3 mL)

Unacceptable Conditions

Contaminated, heat-inactivated, hemolyzed, or severely lipemic specimens.

Storage/Transport Temperature

Refrigerated.

Stability (from collection to initiation)

After separation from cells: Ambient: 48 hours; Refrigerated: 2 weeks; Frozen: 1 year (avoid repeated freeze/thaw cycles)

Notes

This test may be a useful tool for distinguishing ulcerative colitis (UC) from Crohn disease (CD) in patients with suspected inflammatory bowel disease.
Ordering

Performed

Sun-Sat

Methodology

Semi-Quantitative Enzyme-Linked Immunosorbent Assay

Reported

1-2 days

Synonyms

  • SACC CEREVISIAE ABS
  • ASCA IGG/IGA
  • S CEREVISIAE ABS
  • SACCHAROMYCES AB
  • LAB548

Ordering Recommendations

May be useful for the diagnosis of Crohn disease. Test by itself is not diagnostic and should be used in conjunction with other parameters to confirm disease. Inflammatory Bowel Disease Differentiation Panel (2013270) is the preferred test.
Result Interpretation

Reference Interval

Components
Reference Interval
S. cerevisiae Antibody, IgG20.0 Units or less: Negative
20.1-24.9 Units: Equivocal
25.0 Units or greater: Positive
S. cerevisiae Antibody, IgA20.0 Units or less: Negative
20.1-24.9 Units: Equivocal
25.0 Units or greater: Positive

Interpretive Data

Saccharomyces cerevisiae IgG antibodies are found in 60-70% of Crohn disease (CD) patients and 10-15% of ulcerative colitis (UC) patients. Saccharomyces cerevisiae IgA antibodies are found in about 35% of CD patients but less than 1% in UC patients. Detection of both Saccharomyces IgG and IgA antibodies in the same serum specimen is highly specific for CD.

Administrative

CPT Codes

86671 x2

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