N-TELOPEPTIDE - URINE

LAB816

 

Collect

Second-morning void or 24-hour urine. Refrigerate during collection. Collect without preservative.

Patient Preparation

For monitoring therapy, a baseline specimen should be collected prior to initiation of therapy. Subsequent specimens for comparison should be collected at the same time of day as the baseline specimen.

Specimen Preparation

Transfer a 1 mL aliquot of urine from a well-mixed, second-morning void or 24-hour collection to an ARUP Standard Transport Tube. (Min: 0.5 mL)

Unacceptable Conditions

Specimens contaminated with blood or extensive hemolysis.

Storage/Transport Temperature

Frozen.

Stability (from collection to initiation)

Ambient: 24 hours; Refrigerated: 1 week; Frozen: 2 years

Performed

Tue-Sat

Methodology

Quantitative Chemiluminescent Immunoassay

Reported

1-4 days

Synonyms

  • NTx
  • Cross-Linked N-Telopeptide
  • LAB816
  • NTX URINE

Additional Technical Information

Reference Interval

Age
Male
Female
7-9 years167-578 nM BCE/mM creatinine201-626 nM BCE/mM creatinine
10-12 years152-505 nM BCE/mM creatinine173-728 nM BCE/mM creatinine
13-15 years103-776 nM BCE/mM creatinine38-515 nM BCE/mM creatinine
16-17 years34-313 nM BCE/mM creatinine20-144 nM BCE/mM creatinine
18 years and older21-83 nM BCE/mM creatinine
Premenopausal 17-94 nM BCE/mM creatinine
Postmenopausal 26-124 nM BCE/mM creatinine

Interpretive Data

NTx Units = nM BCE/mM creatinine

A decrease of 30-40% from the NTx baseline after three months of therapy is a typical response to anti-resorptive therapy.

NTx = Cross-linked N-telopeptide of Type I Collagen
BCE = Bone Collagen Equivalent

CPT Codes

82523
Collection

LAB816

 

Collect

Second-morning void or 24-hour urine. Refrigerate during collection. Collect without preservative.

Patient Preparation

For monitoring therapy, a baseline specimen should be collected prior to initiation of therapy. Subsequent specimens for comparison should be collected at the same time of day as the baseline specimen.

Specimen Preparation

Transfer a 1 mL aliquot of urine from a well-mixed, second-morning void or 24-hour collection to an ARUP Standard Transport Tube. (Min: 0.5 mL)

Unacceptable Conditions

Specimens contaminated with blood or extensive hemolysis.

Storage/Transport Temperature

Frozen.

Stability (from collection to initiation)

Ambient: 24 hours; Refrigerated: 1 week; Frozen: 2 years
Ordering

Performed

Tue-Sat

Methodology

Quantitative Chemiluminescent Immunoassay

Reported

1-4 days

Synonyms

  • NTx
  • Cross-Linked N-Telopeptide
  • LAB816
  • NTX URINE

Additional Technical Information

Result Interpretation

Reference Interval

Age
Male
Female
7-9 years167-578 nM BCE/mM creatinine201-626 nM BCE/mM creatinine
10-12 years152-505 nM BCE/mM creatinine173-728 nM BCE/mM creatinine
13-15 years103-776 nM BCE/mM creatinine38-515 nM BCE/mM creatinine
16-17 years34-313 nM BCE/mM creatinine20-144 nM BCE/mM creatinine
18 years and older21-83 nM BCE/mM creatinine
Premenopausal 17-94 nM BCE/mM creatinine
Postmenopausal 26-124 nM BCE/mM creatinine

Interpretive Data

NTx Units = nM BCE/mM creatinine

A decrease of 30-40% from the NTx baseline after three months of therapy is a typical response to anti-resorptive therapy.

NTx = Cross-linked N-telopeptide of Type I Collagen
BCE = Bone Collagen Equivalent

Administrative

CPT Codes

82523

N-TELOPEPTIDE,CROSSLINK,SERUM

LAB3171

 

Collect

Plain red or serum separator tube.

Specimen Preparation

Transfer 0.5 mL serum to an ARUP Standard Transport Tube. (Min: 0.2 mL)

Unacceptable Conditions

Severely hemolyzed specimens.

Storage/Transport Temperature

Frozen.

Offsite: Deliver refrigerated within 24 hours.

Stability (from collection to initiation)

After separation from cells: Ambient: 5 hours; Refrigerated: 24 hours; Frozen: 6 months

Performed

Mon, Wed, Fri

Methodology

Quantitative Enzyme-Linked Immunosorbent Assay

Reported

1-4 days

Synonyms

  • Cross-Linked N-Telopeptide, Serum
  • NTx, Serum
  • LAB3171
  • NTX S
  • NTX SERUM

Additional Technical Information

Reference Interval

Adult Male: 5.4-24.2 nM BCE
Premenopausal, Adult Female: 6.2-19.0 nM BCE

Interpretive Data

The target value for treated postmenopausal adult females is the same as the premenopausal reference interval.
BCE = Bone Collagen Equivalent

CPT Codes

82523
Collection

LAB3171

 

Collect

Plain red or serum separator tube.

Specimen Preparation

Transfer 0.5 mL serum to an ARUP Standard Transport Tube. (Min: 0.2 mL)

Unacceptable Conditions

Severely hemolyzed specimens.

Storage/Transport Temperature

Frozen.

Offsite: Deliver refrigerated within 24 hours.

Stability (from collection to initiation)

After separation from cells: Ambient: 5 hours; Refrigerated: 24 hours; Frozen: 6 months
Ordering

Performed

Mon, Wed, Fri

Methodology

Quantitative Enzyme-Linked Immunosorbent Assay

Reported

1-4 days

Synonyms

  • Cross-Linked N-Telopeptide, Serum
  • NTx, Serum
  • LAB3171
  • NTX S
  • NTX SERUM

Additional Technical Information

Result Interpretation

Reference Interval

Adult Male: 5.4-24.2 nM BCE
Premenopausal, Adult Female: 6.2-19.0 nM BCE

Interpretive Data

The target value for treated postmenopausal adult females is the same as the premenopausal reference interval.
BCE = Bone Collagen Equivalent

Administrative

CPT Codes

82523