NEUTROPHIL FUNCTION TESTING

LAB3646

 

Collect

Requires special handling: 20 mL green top [heparinized - Sodium or Lithium] - whole blood. (Dark Green)

SCHEDULE W/LAB PRIOR TO COLLECTION for Bactericidal and Chemotaxis testing.

Call 720-848-7029.

Specimen Preparation

Green tops with gel (PST) acceptable if they are NOT centrifuged (per NJH Immunology Lab).

Unacceptable Conditions

Refrigerated/frozen samples. Samples >24hours old.

Storage/Transport Temperature

Internal: Deliver to lab immediatley. Mon-Thurs only.
Offsite: 20 mL whole blood in plain green top tube Deliver to lab same day. Mon-Thurs only.

Stability (from collection to initiation)

Ambient specimen must be received by Reference lab within 24 hours of collection [testing is performed on live neutrophils.]

Remarks

Various neutrophil function assays available:
Bactericidal - Needs to be scheduled PRIOR to collection.

Chemotaxis - Needs to be scheduled PRIOR to collection.

Please contact the Clinical Lab - Senoduts @ 720-848-7043
M-Th to schedule testing.

Nitroblue Tetrazolium [NBT] dye reduction

Dihydrorhodamine [DHR] (oxidative metabolism).

Performed by

PCL Clinical Laboratory

Performed

Upon receipt

Methodology

Various methods of stimulating neutrophils at various stages of their phogacytic process are used to determine the host neutrophil's phagocytic ability.

Reported

Varies

Synonyms

  • CHEMOTAXIS
  • NBT - NitroblueTetrazolium
  • DHR - Dihydrorhodamine
  • LAB3646
  • NEUTFUNC

Performed by

PCL Clinical Laboratory

CPT Codes

Varies depending on function type:

 

86344 Bactericidal
86155 x2 Chemotaxis
82657 x2 DHR
86384 NBT

Collection

LAB3646

 

Collect

Requires special handling: 20 mL green top [heparinized - Sodium or Lithium] - whole blood. (Dark Green)

SCHEDULE W/LAB PRIOR TO COLLECTION for Bactericidal and Chemotaxis testing.

Call 720-848-7029.

Specimen Preparation

Green tops with gel (PST) acceptable if they are NOT centrifuged (per NJH Immunology Lab).

Unacceptable Conditions

Refrigerated/frozen samples. Samples >24hours old.

Storage/Transport Temperature

Internal: Deliver to lab immediatley. Mon-Thurs only.
Offsite: 20 mL whole blood in plain green top tube Deliver to lab same day. Mon-Thurs only.

Stability (from collection to initiation)

Ambient specimen must be received by Reference lab within 24 hours of collection [testing is performed on live neutrophils.]

Remarks

Various neutrophil function assays available:
Bactericidal - Needs to be scheduled PRIOR to collection.

Chemotaxis - Needs to be scheduled PRIOR to collection.

Please contact the Clinical Lab - Senoduts @ 720-848-7043
M-Th to schedule testing.

Nitroblue Tetrazolium [NBT] dye reduction

Dihydrorhodamine [DHR] (oxidative metabolism).

Performed by

PCL Clinical Laboratory

Ordering

Performed

Upon receipt

Methodology

Various methods of stimulating neutrophils at various stages of their phogacytic process are used to determine the host neutrophil's phagocytic ability.

Reported

Varies

Synonyms

  • CHEMOTAXIS
  • NBT - NitroblueTetrazolium
  • DHR - Dihydrorhodamine
  • LAB3646
  • NEUTFUNC
Result Interpretation

Performed by

PCL Clinical Laboratory

Administrative

CPT Codes

Varies depending on function type:

 

86344 Bactericidal
86155 x2 Chemotaxis
82657 x2 DHR
86384 NBT

NEWBORN GENETIC SCREEN

LAB3024

 

Collect

Filter paper attached to requisition supplied by the Colorado Department of Health with 5 circles for blood collection, preferably from a heel stick. .

Unacceptable Conditions

Not enough blood in circles. Blood layered or diluted. Blotter torn at site of blood collection.

Storage/Transport Temperature

Internal: Deliver to lab immediatley
Offsite: The circles must be filled as completely as possible. Deliver to lab.

Stability (from collection to initiation)

.

Remarks

Requisition with attached filter paper specimen collection card must include infant's last name, sex, ID #, race, mother's first name (last name if other than infant's), date and time of birth, name of facility submitting specimen, physicians name and inf

Performed by

Colorado Department of Public Health

Performed

2 times per week

Methodology

The Newborns Screens [Initial and Repeat] test for the following: Biotinidase deficiency, Congenital Adrenal Hyperplasia, Cystic Fibrosis, Galactosemia, Hemoglobinopathy, Phenylketonuria, Hypothyroidism [T4] and Hypothyroidism [TSH]

Reported

7 - 10 days

Synonyms

  • LAB3024
  • NBS

Reference Interval

 Disorders  Analyte Reference Range 
 Biotinidase Deficiency  Biotinidase  >30 % enzyme activity
 Congenital Adrenal Hyperplasia  17-hydroxyprogesterone (17OHP)  <35 ng/mL
 Congenital Hypothyrodism  Thyroxine (T4)  >=6 ug/dL
 Cystic Fibrosis  Immunoreactive Trypsinogen (IRT)  <60 ng/mL
 Galactosemia  Galactose-1-Phosphate Uridiyl Transferase (GALT)  Presence of enzyme activity
 Hemoglobinopathies  Hemoglobin  F + A
 Phenylketonuria  Phenylalanine  <137 umol/L
 Fatty Acid Oxidation  Disorders    Normal
 Amino Acidemias    Normal
 Organic Acidemias    Normal

Performed by

Colorado Department of Public Health

CPT Codes

84030 PKU
83498 17-alpha-hydroxyprogesterone (CAH)
84437 Thyroxine
82261 Biotinidase
83020 Hemoglobin Electrophoresis
82776 Galactose-1-PUT
83520 Trypsinogen/CF
83788 MS-MS Expanded Screen

Collection

LAB3024

 

Collect

Filter paper attached to requisition supplied by the Colorado Department of Health with 5 circles for blood collection, preferably from a heel stick. .

Unacceptable Conditions

Not enough blood in circles. Blood layered or diluted. Blotter torn at site of blood collection.

Storage/Transport Temperature

Internal: Deliver to lab immediatley
Offsite: The circles must be filled as completely as possible. Deliver to lab.

Stability (from collection to initiation)

.

Remarks

Requisition with attached filter paper specimen collection card must include infant's last name, sex, ID #, race, mother's first name (last name if other than infant's), date and time of birth, name of facility submitting specimen, physicians name and inf

Performed by

Colorado Department of Public Health

Ordering

Performed

2 times per week

Methodology

The Newborns Screens [Initial and Repeat] test for the following: Biotinidase deficiency, Congenital Adrenal Hyperplasia, Cystic Fibrosis, Galactosemia, Hemoglobinopathy, Phenylketonuria, Hypothyroidism [T4] and Hypothyroidism [TSH]

Reported

7 - 10 days

Synonyms

  • LAB3024
  • NBS
Result Interpretation

Reference Interval

 Disorders  Analyte Reference Range 
 Biotinidase Deficiency  Biotinidase  >30 % enzyme activity
 Congenital Adrenal Hyperplasia  17-hydroxyprogesterone (17OHP)  <35 ng/mL
 Congenital Hypothyrodism  Thyroxine (T4)  >=6 ug/dL
 Cystic Fibrosis  Immunoreactive Trypsinogen (IRT)  <60 ng/mL
 Galactosemia  Galactose-1-Phosphate Uridiyl Transferase (GALT)  Presence of enzyme activity
 Hemoglobinopathies  Hemoglobin  F + A
 Phenylketonuria  Phenylalanine  <137 umol/L
 Fatty Acid Oxidation  Disorders    Normal
 Amino Acidemias    Normal
 Organic Acidemias    Normal

Performed by

Colorado Department of Public Health

Administrative

CPT Codes

84030 PKU
83498 17-alpha-hydroxyprogesterone (CAH)
84437 Thyroxine
82261 Biotinidase
83020 Hemoglobin Electrophoresis
82776 Galactose-1-PUT
83520 Trypsinogen/CF
83788 MS-MS Expanded Screen

NEWBORN TRANSFUSION EVALUATION

Collect

Neonatal or pre-delivery maternal blood specimens are acceptable.

Cord and neonatal heelsticks are drawn in a pink or purple microtainer and must be filled to the 500 mark.

Also acceptable: 6 mL pink top (EDTA) tube, 3 mL red top (clotted blood) tube, or 3 mL purple top (EDTA) tube.

Label with last name, first name, medical record number, date drawn, phlebotomist's initials and second set of initials, according to "Administration of Blood Components" policy.

Unacceptable Conditions

Grossly hemolyzed, specimen not properly labeled, incorrect container, insufficient sample volume.

Storage/Transport Temperature

Internal: Deliver to lab immediately.
Offsite: Deliver to lab immediately at ambient temperature.

Stability (from collection to initiation)

8 hours at ambient temperature.

Remarks

Red blood cells are available as neonatal aliquots in a syringe. For exchange transfusion, mother's blood is strongly recommended, if available, for crossmatch. Provide as much advance notice as possible to permit availability of most appropriate unit.

Performed by

PCL Clinical Laboratory - Transfusion Service (Blood Bank)

Performed

Daily

Methodology

Hemagglutination

Reported

Same day

Performed by

PCL Clinical Laboratory - Transfusion Service (Blood Bank)

Collection

Collect

Neonatal or pre-delivery maternal blood specimens are acceptable.

Cord and neonatal heelsticks are drawn in a pink or purple microtainer and must be filled to the 500 mark.

Also acceptable: 6 mL pink top (EDTA) tube, 3 mL red top (clotted blood) tube, or 3 mL purple top (EDTA) tube.

Label with last name, first name, medical record number, date drawn, phlebotomist's initials and second set of initials, according to "Administration of Blood Components" policy.

Unacceptable Conditions

Grossly hemolyzed, specimen not properly labeled, incorrect container, insufficient sample volume.

Storage/Transport Temperature

Internal: Deliver to lab immediately.
Offsite: Deliver to lab immediately at ambient temperature.

Stability (from collection to initiation)

8 hours at ambient temperature.

Remarks

Red blood cells are available as neonatal aliquots in a syringe. For exchange transfusion, mother's blood is strongly recommended, if available, for crossmatch. Provide as much advance notice as possible to permit availability of most appropriate unit.

Performed by

PCL Clinical Laboratory - Transfusion Service (Blood Bank)

Ordering

Performed

Daily

Methodology

Hemagglutination

Reported

Same day
Result Interpretation

Performed by

PCL Clinical Laboratory - Transfusion Service (Blood Bank)

Administrative

NICOTINE + COTININE LEVELS

Collect

Neonatal or pre-delivery maternal blood specimens are acceptable.

Cord and neonatal heelsticks are drawn in a pink or purple microtainer and must be filled to the 500 mark.

Also acceptable: 6 mL pink top (EDTA) tube, 3 mL red top (clotted blood) tube, or 3 mL purple top (EDTA) tube.

Label with last name, first name, medical record number, date drawn, phlebotomist's initials and second set of initials, according to "Administration of Blood Components" policy.

Unacceptable Conditions

Grossly hemolyzed, specimen not properly labeled, incorrect container, insufficient sample volume.

Storage/Transport Temperature

Internal: Deliver to lab immediately.
Offsite: Deliver to lab immediately at ambient temperature.

Stability (from collection to initiation)

8 hours at ambient temperature.

Remarks

Red blood cells are available as neonatal aliquots in a syringe. For exchange transfusion, mother's blood is strongly recommended, if available, for crossmatch. Provide as much advance notice as possible to permit availability of most appropriate unit.

Performed by

PCL Clinical Laboratory - Transfusion Service (Blood Bank)

Performed

Daily

Methodology

Hemagglutination

Reported

Same day

Performed by

PCL Clinical Laboratory - Transfusion Service (Blood Bank)

Collection

Collect

Neonatal or pre-delivery maternal blood specimens are acceptable.

Cord and neonatal heelsticks are drawn in a pink or purple microtainer and must be filled to the 500 mark.

Also acceptable: 6 mL pink top (EDTA) tube, 3 mL red top (clotted blood) tube, or 3 mL purple top (EDTA) tube.

Label with last name, first name, medical record number, date drawn, phlebotomist's initials and second set of initials, according to "Administration of Blood Components" policy.

Unacceptable Conditions

Grossly hemolyzed, specimen not properly labeled, incorrect container, insufficient sample volume.

Storage/Transport Temperature

Internal: Deliver to lab immediately.
Offsite: Deliver to lab immediately at ambient temperature.

Stability (from collection to initiation)

8 hours at ambient temperature.

Remarks

Red blood cells are available as neonatal aliquots in a syringe. For exchange transfusion, mother's blood is strongly recommended, if available, for crossmatch. Provide as much advance notice as possible to permit availability of most appropriate unit.

Performed by

PCL Clinical Laboratory - Transfusion Service (Blood Bank)

Ordering

Performed

Daily

Methodology

Hemagglutination

Reported

Same day
Result Interpretation

Performed by

PCL Clinical Laboratory - Transfusion Service (Blood Bank)

Administrative

NICOTINE URINE

LAB3979

Collect

Random urine.

Specimen Preparation

Transfer 4 mL with no additives or preservatives urine to an ARUP Standard Transport Tube. (Min: 1 mL)

Unacceptable Conditions

Specimens exposed to repeated freeze/thaw cycles.

Storage/Transport Temperature

Room temperature.

Stability (from collection to initiation)

Ambient: 10 days; Refrigerated: 10 days; Frozen: 8 months

Performed

Sun-Sat

Methodology

Quantitative Liquid Chromatography-Tandem Mass Spectrometry

Reported

1-4 days

Synonyms

  • Pain Management
  • Anabasine
  • Cotinine
  • Nornicotine
  • 3-Hydroxycotinine
  • Nicotine and Cotinine, LC/MS/MS, Urine
  • NICOTINE U
  • LAB3979

Additional Technical Information

Ordering Recommendations

Recommended for determination of active or passive nicotine use or for differentiation between nicotine replacement and tobacco use. For a screening test to determine active exposure to nicotine and compliance with smoking-cessation programs, Cotinine Screen, Urine (2007081) is preferred.

Reference Interval

Effective August 17, 2015
Drugs CoveredCutoff Concentrations
Nicotine2 ng/mL
Cotinine (metabolite)5 ng/mL
3-OH-Cotinine (metabolite)50 ng/mL
Nornicotine (metabolite)2 ng/mL
Anabasine (tobacco biomarker)3 ng/mL

Interpretive Data

Methodology: Quantitative Liquid Chromatography-Tandem Mass Spectrometry

Positive cutoff
:
Nicotine                2 ng/mL
Cotinine                5 ng/mL
3-OH-Cotinine          50 ng/mL
Nornicotine             2 ng/mL
Anabasine              3 ng/mL

For medical purposes only; not valid for forensic use.

This test is designed to evaluate recent use of nicotine-containing products. Passive and active exposure cannot be discriminated definitively, although a cutoff of 100 ng/mL cotinine is frequently used for surgery qualification purposes. For smoking cessation programs or compliance testing, the absence of expected drug(s) and/or drug metabolite(s) may indicate non-compliance, inappropriate timing of specimen collection relative to drug administration, poor drug absorption, diluted/adulterated urine, or limitations of testing. The concentration value must be greater than or equal to the cutoff to be reported as positive. Anabasine is included as a biomarker of tobacco use, versus nicotine replacement. Interpretive questions should be directed to the laboratory. 

CPT Codes

80323 (Alt code: G0480)
Collection

LAB3979

Collect

Random urine.

Specimen Preparation

Transfer 4 mL with no additives or preservatives urine to an ARUP Standard Transport Tube. (Min: 1 mL)

Unacceptable Conditions

Specimens exposed to repeated freeze/thaw cycles.

Storage/Transport Temperature

Room temperature.

Stability (from collection to initiation)

Ambient: 10 days; Refrigerated: 10 days; Frozen: 8 months
Ordering

Performed

Sun-Sat

Methodology

Quantitative Liquid Chromatography-Tandem Mass Spectrometry

Reported

1-4 days

Synonyms

  • Pain Management
  • Anabasine
  • Cotinine
  • Nornicotine
  • 3-Hydroxycotinine
  • Nicotine and Cotinine, LC/MS/MS, Urine
  • NICOTINE U
  • LAB3979

Additional Technical Information

Ordering Recommendations

Recommended for determination of active or passive nicotine use or for differentiation between nicotine replacement and tobacco use. For a screening test to determine active exposure to nicotine and compliance with smoking-cessation programs, Cotinine Screen, Urine (2007081) is preferred.
Result Interpretation

Reference Interval

Effective August 17, 2015
Drugs CoveredCutoff Concentrations
Nicotine2 ng/mL
Cotinine (metabolite)5 ng/mL
3-OH-Cotinine (metabolite)50 ng/mL
Nornicotine (metabolite)2 ng/mL
Anabasine (tobacco biomarker)3 ng/mL

Interpretive Data

Methodology: Quantitative Liquid Chromatography-Tandem Mass Spectrometry

Positive cutoff
:
Nicotine                2 ng/mL
Cotinine                5 ng/mL
3-OH-Cotinine          50 ng/mL
Nornicotine             2 ng/mL
Anabasine              3 ng/mL

For medical purposes only; not valid for forensic use.

This test is designed to evaluate recent use of nicotine-containing products. Passive and active exposure cannot be discriminated definitively, although a cutoff of 100 ng/mL cotinine is frequently used for surgery qualification purposes. For smoking cessation programs or compliance testing, the absence of expected drug(s) and/or drug metabolite(s) may indicate non-compliance, inappropriate timing of specimen collection relative to drug administration, poor drug absorption, diluted/adulterated urine, or limitations of testing. The concentration value must be greater than or equal to the cutoff to be reported as positive. Anabasine is included as a biomarker of tobacco use, versus nicotine replacement. Interpretive questions should be directed to the laboratory. 

Administrative

CPT Codes

80323 (Alt code: G0480)

NMDAR AB IGG W/REFLEX TO TITER (CSF)

LAB5066

Collect

CSF.

Specimen Preparation

Transfer 0.5 mL CSF to an ARUP Standard Transport Tube. (Min: 0.15 mL)

Unacceptable Conditions

Contaminated, hemolyzed, or severely lipemic specimens.

Storage/Transport Temperature

Refrigerated.

Stability (from collection to initiation)

Ambient: 48 hours; Refrigerated: 2 weeks; Frozen: 1 year (avoid repeated freeze/thaw cycles)

Notes

If NMDA CSF antibody IgG is positive, then an NMDA CSF antibody IgG titer is reported. Additional charges apply.

Performed

Tue, Fri

Methodology

Semi-Quantitative Indirect Fluorescent Antibody

Reported

1-5 days

Synonyms

  • LAB5066
  • NMDARC IGG
  • NMDAR CSF

Additional Technical Information

Ordering Recommendations

Confirm diagnosis of anti-NMDAR encephalitis. May be used in monitoring treatment response in individuals who are antibody positive.

Reference Interval

Effective May 21, 2012
< 1:1

Interpretive Data

Anti-NMDA receptor IgG antibody is found in a subset of patients with autoimmune limbic encephalitis and may occur with or without associated tumor. Decreasing antibody levels may be associated with therapeutic response; therefore, clinical correlation must be strongly considered. A negative test result does not rule out a diagnosis of autoimmune limbic encephalitis.

CPT Codes

86255; if reflexed, add 86256
Collection

LAB5066

Collect

CSF.

Specimen Preparation

Transfer 0.5 mL CSF to an ARUP Standard Transport Tube. (Min: 0.15 mL)

Unacceptable Conditions

Contaminated, hemolyzed, or severely lipemic specimens.

Storage/Transport Temperature

Refrigerated.

Stability (from collection to initiation)

Ambient: 48 hours; Refrigerated: 2 weeks; Frozen: 1 year (avoid repeated freeze/thaw cycles)

Notes

If NMDA CSF antibody IgG is positive, then an NMDA CSF antibody IgG titer is reported. Additional charges apply.
Ordering

Performed

Tue, Fri

Methodology

Semi-Quantitative Indirect Fluorescent Antibody

Reported

1-5 days

Synonyms

  • LAB5066
  • NMDARC IGG
  • NMDAR CSF

Additional Technical Information

Ordering Recommendations

Confirm diagnosis of anti-NMDAR encephalitis. May be used in monitoring treatment response in individuals who are antibody positive.
Result Interpretation

Reference Interval

Effective May 21, 2012
< 1:1

Interpretive Data

Anti-NMDA receptor IgG antibody is found in a subset of patients with autoimmune limbic encephalitis and may occur with or without associated tumor. Decreasing antibody levels may be associated with therapeutic response; therefore, clinical correlation must be strongly considered. A negative test result does not rule out a diagnosis of autoimmune limbic encephalitis.

Administrative

CPT Codes

86255; if reflexed, add 86256

NMDAR AB IGG W/REFLEX TO TITER (SERUM)

LAB5065

Collect

Serum separator tube.

Specimen Preparation

Separate serum from cells ASAP or within 2 hours of collection. Transfer 1 mL serum to an ARUP Standard Transport Tube. (Min: 0.15 mL)

Unacceptable Conditions

CSF or plasma. Contaminated, hemolyzed, or severely lipemic specimens.

Storage/Transport Temperature

Refrigerated.

Stability (from collection to initiation)

After separation from cells: Ambient: 48 hours; Refrigerated: 2 weeks; Frozen: 1 year (avoid repeated freeze/thaw cycles)

Notes

If NMDA antibody IgG is positive, then an NMDA antibody IgG titer is reported. Additional charges apply.

Performed

Tue, Fri

Methodology

Semi-Quantitative Indirect Fluorescent Antibody

Reported

1-5 days

Synonyms

  • LAB5065
  • Glutamate Receptor Antibodies
  • NMDA R
  • NMDA Receptor Ab
  • N-Methyl D-Aspartate Ab
  • Anti-NMDA
  • NMDA Titer
  • NMDA Reflex
  • NMDAR

Additional Technical Information

Ordering Recommendations

Confirm diagnosis of anti-NMDAR encephalitis. May be used in monitoring treatment response in individuals who are antibody positive.

Reference Interval

< 1:10

Interpretive Data

Anti-NMDA receptor IgG antibody is found in a subset of patients with autoimmune limbic encephalitis and may occur with or without associated tumor. Decreasing antibody levels may be associated with therapeutic response; therefore, clinical correlation must be strongly considered. A negative test result does not rule out a diagnosis of autoimmune limbic encephalitis.

CPT Codes

86255; if reflexed, add 86256
Collection

LAB5065

Collect

Serum separator tube.

Specimen Preparation

Separate serum from cells ASAP or within 2 hours of collection. Transfer 1 mL serum to an ARUP Standard Transport Tube. (Min: 0.15 mL)

Unacceptable Conditions

CSF or plasma. Contaminated, hemolyzed, or severely lipemic specimens.

Storage/Transport Temperature

Refrigerated.

Stability (from collection to initiation)

After separation from cells: Ambient: 48 hours; Refrigerated: 2 weeks; Frozen: 1 year (avoid repeated freeze/thaw cycles)

Notes

If NMDA antibody IgG is positive, then an NMDA antibody IgG titer is reported. Additional charges apply.
Ordering

Performed

Tue, Fri

Methodology

Semi-Quantitative Indirect Fluorescent Antibody

Reported

1-5 days

Synonyms

  • LAB5065
  • Glutamate Receptor Antibodies
  • NMDA R
  • NMDA Receptor Ab
  • N-Methyl D-Aspartate Ab
  • Anti-NMDA
  • NMDA Titer
  • NMDA Reflex
  • NMDAR

Additional Technical Information

Ordering Recommendations

Confirm diagnosis of anti-NMDAR encephalitis. May be used in monitoring treatment response in individuals who are antibody positive.
Result Interpretation

Reference Interval

< 1:10

Interpretive Data

Anti-NMDA receptor IgG antibody is found in a subset of patients with autoimmune limbic encephalitis and may occur with or without associated tumor. Decreasing antibody levels may be associated with therapeutic response; therefore, clinical correlation must be strongly considered. A negative test result does not rule out a diagnosis of autoimmune limbic encephalitis.

Administrative

CPT Codes

86255; if reflexed, add 86256

NOROVIRUS BY PCR

LAB3331

 

Collect

Stool.

Specimen Preparation

Transfer 1 mL stool to an unpreserved stool transport vial (ARUP Supply #40910).  Available online through eSupply using ARUP Connectâ„¢ or contact ARUP Client Services at (800) 522-2787. (Min: 0.5 mL).

Storage/Transport Temperature

Internal: Deliver to lab immediatley
Offsite: 5 g Deliver to lab on cold packs.

Cary-Blair transport media (not a preservative) acceptable at ARUP.

Stability (from collection to initiation)

Ambient: 8 hours; Refrigerated: 72 hours; Frozen: 1 month

Performed

Mon, Wed, Fri

Methodology

Qualitative Reverse Transcription Polymerase Chain Reaction

Reported

In 2 days

Synonyms

  • LAB3331
  • NORO PCR
  • NOROVPCR
  • NORO

Ordering Recommendations

Detect norovirus groups 1 and 2.

Interpretive Data

A negative result does not rule out the presence of PCR inhibitors in the patient specimen or test-specific nucleic acid in concentrations below the level of detection by this test.

CPT Codes

87798 x2
Collection

LAB3331

 

Collect

Stool.

Specimen Preparation

Transfer 1 mL stool to an unpreserved stool transport vial (ARUP Supply #40910).  Available online through eSupply using ARUP Connectâ„¢ or contact ARUP Client Services at (800) 522-2787. (Min: 0.5 mL).

Storage/Transport Temperature

Internal: Deliver to lab immediatley
Offsite: 5 g Deliver to lab on cold packs.

Cary-Blair transport media (not a preservative) acceptable at ARUP.

Stability (from collection to initiation)

Ambient: 8 hours; Refrigerated: 72 hours; Frozen: 1 month
Ordering

Performed

Mon, Wed, Fri

Methodology

Qualitative Reverse Transcription Polymerase Chain Reaction

Reported

In 2 days

Synonyms

  • LAB3331
  • NORO PCR
  • NOROVPCR
  • NORO

Ordering Recommendations

Detect norovirus groups 1 and 2.
Result Interpretation

Interpretive Data

A negative result does not rule out the presence of PCR inhibitors in the patient specimen or test-specific nucleic acid in concentrations below the level of detection by this test.

Administrative

CPT Codes

87798 x2

NORTRIPTYLINE

LAB807

 

Collect

Plain red. Also acceptable: Lavender (K2 or K3EDTA) or pink (K2EDTA).

Patient Preparation

If amitriptyline is administered, order Amitriptyline and Nortriptyline (ARUP test code 0090158).  Timing of specimen collection: Pre-dose (trough) draw - At steady state concentration.

Specimen Preparation

Separate serum or plasma from cells within 2 hours of collection. Transfer 1 mL serum or plasma to an ARUP Standard Transport Tube. (Min: 0.5 mL)

Unacceptable Conditions

Whole blood. Gel separator tubes, light blue (citrate), or yellow (SPS or ACD solution).

Storage/Transport Temperature

Refrigerated.

Stability (from collection to initiation)

After separation from cells: Ambient: 5 days; Refrigerated: 2 weeks; Frozen: 6 months

Performed

Mon, Wed, Fri

Methodology

Quantitative Liquid Chromatography-Tandem Mass Spectrometry

Reported

1-4 days

Synonyms

  • Aventyl by HPLC
  • Pamelor by HPLC
  • Aventyl
  • Pamelor
  • LAB807
  • NORTRIPT

Ordering Recommendations

Optimize drug therapy and monitor patient adherence.

Reference Interval

Therapeutic Range:
50-150 ng/mL
Toxic: > 500 ng/mL

Interpretive Data

Toxic concentrations may cause anticholinergic effects, cardiac abnormalities and seizures.

CPT Codes

80335 (Alt code: G0480)
Collection

LAB807

 

Collect

Plain red. Also acceptable: Lavender (K2 or K3EDTA) or pink (K2EDTA).

Patient Preparation

If amitriptyline is administered, order Amitriptyline and Nortriptyline (ARUP test code 0090158).  Timing of specimen collection: Pre-dose (trough) draw - At steady state concentration.

Specimen Preparation

Separate serum or plasma from cells within 2 hours of collection. Transfer 1 mL serum or plasma to an ARUP Standard Transport Tube. (Min: 0.5 mL)

Unacceptable Conditions

Whole blood. Gel separator tubes, light blue (citrate), or yellow (SPS or ACD solution).

Storage/Transport Temperature

Refrigerated.

Stability (from collection to initiation)

After separation from cells: Ambient: 5 days; Refrigerated: 2 weeks; Frozen: 6 months
Ordering

Performed

Mon, Wed, Fri

Methodology

Quantitative Liquid Chromatography-Tandem Mass Spectrometry

Reported

1-4 days

Synonyms

  • Aventyl by HPLC
  • Pamelor by HPLC
  • Aventyl
  • Pamelor
  • LAB807
  • NORTRIPT

Ordering Recommendations

Optimize drug therapy and monitor patient adherence.
Result Interpretation

Reference Interval

Therapeutic Range:
50-150 ng/mL
Toxic: > 500 ng/mL

Interpretive Data

Toxic concentrations may cause anticholinergic effects, cardiac abnormalities and seizures.

Administrative

CPT Codes

80335 (Alt code: G0480)

NPM1 MUTATION BY PCR

LAB3748

Collect

4.0 mL EDTA whole blood (or bone marrow), purple or pink

Specimen Preparation

1.0 mL minimum volume

Unacceptable Conditions

Serum. Frozen.

Storage/Transport Temperature

Ambient or refrigerated.

Performed by

PCL Clinical Laboratory

Performed

2 days a week

Methodology

PCR

Reported

7-10 days

Synonyms

  • LAB3748
  • NPM1PCR
  • NPM1

Reference Interval

No molecular evidence of NPM1 mutation.

Performed by

PCL Clinical Laboratory

CPT Codes

81310

Collection

LAB3748

Collect

4.0 mL EDTA whole blood (or bone marrow), purple or pink

Specimen Preparation

1.0 mL minimum volume

Unacceptable Conditions

Serum. Frozen.

Storage/Transport Temperature

Ambient or refrigerated.

Performed by

PCL Clinical Laboratory

Ordering

Performed

2 days a week

Methodology

PCR

Reported

7-10 days

Synonyms

  • LAB3748
  • NPM1PCR
  • NPM1
Result Interpretation

Reference Interval

No molecular evidence of NPM1 mutation.

Performed by

PCL Clinical Laboratory

Administrative

CPT Codes

81310

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