GABAPENTIN - NEURONTIN

LAB470

Collect

Plain red. Also acceptable: Lavender (K2 or K3EDTA) or pink (K2EDTA).

Patient Preparation

Timing of specimen collection: Pre-dose (trough) draw - At steady state concentration.

Specimen Preparation

Separate serum or plasma from cells within 2 hours of collection. Transfer 1 mL serum or plasma to an ARUP Standard Transport Tube. (Min: 0.2 mL)

Unacceptable Conditions

Whole blood. Gel separator tubes, light blue (citrate), or yellow (SPS or ACD solution).

Storage/Transport Temperature

Refrigerated.

Stability (from collection to initiation)

After separation from cells: Ambient: 1 month; Refrigerated: 1 month; Frozen: 2 months

Performed

Tue-Sat

Methodology

Quantitative Liquid Chromatography-Tandem Mass Spectrometry

Reported

1-4 days

Synonyms

  • Neurontin
  • Gabapentin, Free
  • LAB470
  • Gabarone

Ordering Recommendations

Optimize drug therapy and monitor patient adherence.

Reference Interval

Effective November 18, 2013
Therapeutic Range2-20 µg/mL
ToxicNot well established

Interpretive Data

Pharmacokinetics of gabapentin vary widely among patients, particularly those with compromised renal function. Adverse effects may include somnolence, dizziness, ataxia, and fatigue.

CPT Codes

80171
Collection

LAB470

Collect

Plain red. Also acceptable: Lavender (K2 or K3EDTA) or pink (K2EDTA).

Patient Preparation

Timing of specimen collection: Pre-dose (trough) draw - At steady state concentration.

Specimen Preparation

Separate serum or plasma from cells within 2 hours of collection. Transfer 1 mL serum or plasma to an ARUP Standard Transport Tube. (Min: 0.2 mL)

Unacceptable Conditions

Whole blood. Gel separator tubes, light blue (citrate), or yellow (SPS or ACD solution).

Storage/Transport Temperature

Refrigerated.

Stability (from collection to initiation)

After separation from cells: Ambient: 1 month; Refrigerated: 1 month; Frozen: 2 months
Ordering

Performed

Tue-Sat

Methodology

Quantitative Liquid Chromatography-Tandem Mass Spectrometry

Reported

1-4 days

Synonyms

  • Neurontin
  • Gabapentin, Free
  • LAB470
  • Gabarone

Ordering Recommendations

Optimize drug therapy and monitor patient adherence.
Result Interpretation

Reference Interval

Effective November 18, 2013
Therapeutic Range2-20 µg/mL
ToxicNot well established

Interpretive Data

Pharmacokinetics of gabapentin vary widely among patients, particularly those with compromised renal function. Adverse effects may include somnolence, dizziness, ataxia, and fatigue.

Administrative

CPT Codes

80171

GALACTOKINASE, WHOLE BLOOD

LAB993

Collect

5 mL green top [heparinized] - whole blood .

Unacceptable Conditions

Frozen samples.
NOT heparinized whole blood.

Storage/Transport Temperature

Internal: Deliver to lab immediatley
Offsite: 3 mL Heparinized whole blood

Ship at ambient temp.

Must arrive at Mayo Medical Lab within 48 hours

Remarks

Do not freeze sample.

Performed by

Mayo Medical Laboratories

Performed

Tue

Methodology

Radioisotopic

Reported

.

Synonyms

  • LAB993

Performed by

Mayo Medical Laboratories

CPT Codes

82759

Collection

LAB993

Collect

5 mL green top [heparinized] - whole blood .

Unacceptable Conditions

Frozen samples.
NOT heparinized whole blood.

Storage/Transport Temperature

Internal: Deliver to lab immediatley
Offsite: 3 mL Heparinized whole blood

Ship at ambient temp.

Must arrive at Mayo Medical Lab within 48 hours

Remarks

Do not freeze sample.

Performed by

Mayo Medical Laboratories

Ordering

Performed

Tue

Methodology

Radioisotopic

Reported

.

Synonyms

  • LAB993
Result Interpretation

Performed by

Mayo Medical Laboratories

Administrative

CPT Codes

82759

GALACTOSE-1-PHOS URIDYLTRANSF

LAB994

Collect

Green (sodium or lithium heparin), lavender (EDTA), or pink (K2EDTA). Collect on ice.

Specimen Preparation

DO NOT FREEZE. Transport 7 mL whole blood. (Min: 3 mL)

Unacceptable Conditions

Hemolyzed specimens.

Storage/Transport Temperature

Refrigerated.

Stability (from collection to initiation)

Ambient: Unacceptable; Refrigerated: 5 days; Frozen: Unacceptable

Notes

Enzyme activity only may not differentiate variant form of galactosemia or carriers.  For a more accurate evaluation of patients suspected to have galactosemia the preferred test is Galactosemia, Panel (0051175). To monitor therapy in patients with galactosemia, order Galactose-1-Phosphate in Red Blood Cells (0081296).

Performed

Mon, Wed, Fri

Methodology

Enzymatic

Reported

2-5 days

Synonyms

  • Beutler Test
  • LAB994

Ordering Recommendations

Galactosemia (GALT) enzyme test. Initial test to diagnose or rule out galactosemia.

Reference Interval

14.7-25.4 U/g Hb

Interpretive Data

One U/g Hb is equivalent to one umol/hour/gram of hemoglobin (umol/hr/g Hb).
 
Note: Values for enzyme activity only may not differentiate between variant form of galactosemia or carriers. For a more accurate evaluation of patients suspected to have galactosemia, the preferred test is Galactosemia (GALT) Enzyme Activity and 9 Mutations (ARUP test code 0051175). To monitor therapy in patients with galactosemia, order Galactose-1-Phosphate in Red Blood Cells (ARUP test code 0081296).

CPT Codes

82775
Collection

LAB994

Collect

Green (sodium or lithium heparin), lavender (EDTA), or pink (K2EDTA). Collect on ice.

Specimen Preparation

DO NOT FREEZE. Transport 7 mL whole blood. (Min: 3 mL)

Unacceptable Conditions

Hemolyzed specimens.

Storage/Transport Temperature

Refrigerated.

Stability (from collection to initiation)

Ambient: Unacceptable; Refrigerated: 5 days; Frozen: Unacceptable

Notes

Enzyme activity only may not differentiate variant form of galactosemia or carriers.  For a more accurate evaluation of patients suspected to have galactosemia the preferred test is Galactosemia, Panel (0051175). To monitor therapy in patients with galactosemia, order Galactose-1-Phosphate in Red Blood Cells (0081296).
Ordering

Performed

Mon, Wed, Fri

Methodology

Enzymatic

Reported

2-5 days

Synonyms

  • Beutler Test
  • LAB994

Ordering Recommendations

Galactosemia (GALT) enzyme test. Initial test to diagnose or rule out galactosemia.
Result Interpretation

Reference Interval

14.7-25.4 U/g Hb

Interpretive Data

One U/g Hb is equivalent to one umol/hour/gram of hemoglobin (umol/hr/g Hb).
 
Note: Values for enzyme activity only may not differentiate between variant form of galactosemia or carriers. For a more accurate evaluation of patients suspected to have galactosemia, the preferred test is Galactosemia (GALT) Enzyme Activity and 9 Mutations (ARUP test code 0051175). To monitor therapy in patients with galactosemia, order Galactose-1-Phosphate in Red Blood Cells (ARUP test code 0081296).

Administrative

CPT Codes

82775

GAMMA GLUTAMYLTRANSFERAS (GGT)

LAB85

GGT

 

Collect

Green top tube with gel separator

Red top tube with or without gel separator, Green top tube without gel separator.

 

Pediatric Collection

Minimum volume: 0.2 mL plasma/serum

Unacceptable Conditions

Sample not properly identified; incorrect container; insufficient sample volume.

Storage/Transport Temperature

Internal: Deliver to lab immediately.

Offsite: Plasma: Centrifuge within 30 minutes of collection.Serum: Allow 20 minutes for serum samples to clot. Centrifuge within 30 minutes of collection. Transport to laboratory at ambient temperature.

Stability (from collection to initiation)

Plasma/Serum: Ambient: 7 days; Refrigerated: 7 days; Frozen: 1 year.

Performed by

PCL Clinical Laboratory - Core

Performed

Daily

Methodology

Coupled Enzymatic

Reported

Same day

Synonyms

  • LAB85
  • GGT
  • GAMMA GLUTAMYL TRANSFERASE

Reference Interval

Effective 05/20/2014:

9 - 64 U/L

 

Before 05/20/2014:

Sex From Age To Age Normal Low Normal High Units
F 3M 15 5 35 U/L
F 15 150 5 36 U/L
M 3M 15 5 65 U/L
M 15 150 8 61 U/L
M/F 0 3W 0 130 U/L
M/F 3W 3M 4 120 U/L

Interpretive Data

Adult reference range.

Performed by

PCL Clinical Laboratory - Core

CPT Codes

82977

Collection

LAB85

GGT

 

Collect

Green top tube with gel separator

Red top tube with or without gel separator, Green top tube without gel separator.

 

Pediatric Collection

Minimum volume: 0.2 mL plasma/serum

Unacceptable Conditions

Sample not properly identified; incorrect container; insufficient sample volume.

Storage/Transport Temperature

Internal: Deliver to lab immediately.

Offsite: Plasma: Centrifuge within 30 minutes of collection.Serum: Allow 20 minutes for serum samples to clot. Centrifuge within 30 minutes of collection. Transport to laboratory at ambient temperature.

Stability (from collection to initiation)

Plasma/Serum: Ambient: 7 days; Refrigerated: 7 days; Frozen: 1 year.

Performed by

PCL Clinical Laboratory - Core

Ordering

Performed

Daily

Methodology

Coupled Enzymatic

Reported

Same day

Synonyms

  • LAB85
  • GGT
  • GAMMA GLUTAMYL TRANSFERASE
Result Interpretation

Reference Interval

Effective 05/20/2014:

9 - 64 U/L

 

Before 05/20/2014:

Sex From Age To Age Normal Low Normal High Units
F 3M 15 5 35 U/L
F 15 150 5 36 U/L
M 3M 15 5 65 U/L
M 15 150 8 61 U/L
M/F 0 3W 0 130 U/L
M/F 3W 3M 4 120 U/L

Interpretive Data

Adult reference range.

Performed by

PCL Clinical Laboratory - Core

Administrative

CPT Codes

82977

GAMMA HYDROXYBUTYRIC ACID S/P

LAB3153

 

Collect

Plain red, lavender (EDTA), or pink (K2EDTA). Also acceptable: Gray (sodium fluoride/potassium oxalate) or green (sodium heparin).

Specimen Preparation

Separate serum or plasma from cells within 2 hours. Transfer 5 mL serum or Plasma to ARUP Standard Transport Tubes. (Min: 2.4 mL)

Unacceptable Conditions

Separator tubes or citrate buffered tubes.

Storage/Transport Temperature

Refrigerated. Also acceptable: Room temperature or frozen.

Stability (from collection to initiation)

Ambient: 1 week; Refrigerated: 1 week; Frozen: 2 months

Performed

Varies

Methodology

Qualitative Gas Chromatography-Mass Spectrometry/Quantitative Gas Chromatography-Mass Spectrometry

Reported

4-10 days

Synonyms

  • GHB
  • LAB3153

Reference Interval

By report

CPT Codes

80307; if positive add 80375 (Alt code: if positive add G0480)
Collection

LAB3153

 

Collect

Plain red, lavender (EDTA), or pink (K2EDTA). Also acceptable: Gray (sodium fluoride/potassium oxalate) or green (sodium heparin).

Specimen Preparation

Separate serum or plasma from cells within 2 hours. Transfer 5 mL serum or Plasma to ARUP Standard Transport Tubes. (Min: 2.4 mL)

Unacceptable Conditions

Separator tubes or citrate buffered tubes.

Storage/Transport Temperature

Refrigerated. Also acceptable: Room temperature or frozen.

Stability (from collection to initiation)

Ambient: 1 week; Refrigerated: 1 week; Frozen: 2 months
Ordering

Performed

Varies

Methodology

Qualitative Gas Chromatography-Mass Spectrometry/Quantitative Gas Chromatography-Mass Spectrometry

Reported

4-10 days

Synonyms

  • GHB
  • LAB3153
Result Interpretation

Reference Interval

By report
Administrative

CPT Codes

80307; if positive add 80375 (Alt code: if positive add G0480)

Gastric pH

LAB3328

PH GAST

Collect

At least 1.0 mL gastric fluid in a sterile urine container.

Pediatric Collection

1 mL minimum volume.

Unacceptable Conditions

Sample not properly identified; incorrect container; insufficient sample volume.

Storage/Transport Temperature

Internal: Deliver to laboratory immediately at ambient temperature.

Offsite: Transport refrigerated.

Stability (from collection to initiation)

Ambient: 4 hours; Refrigerated: 24 hours; Frozen (-20 degrees C): 3 months.

Notes

pH, fluid volume, and hydrogen ion concentration will be reported.

Performed

Daily

Methodology

Ion selective electrode (ISE)

Reported

Same day

Synonyms

  • LAB3328
  • Gastric Fluid pH

Reference Interval

pH: 1.5 - 3.5

Hydrogen ion concentration: 0.39 - 39.60 mEq/L

CPT Codes

83986

Collection

LAB3328

PH GAST

Collect

At least 1.0 mL gastric fluid in a sterile urine container.

Pediatric Collection

1 mL minimum volume.

Unacceptable Conditions

Sample not properly identified; incorrect container; insufficient sample volume.

Storage/Transport Temperature

Internal: Deliver to laboratory immediately at ambient temperature.

Offsite: Transport refrigerated.

Stability (from collection to initiation)

Ambient: 4 hours; Refrigerated: 24 hours; Frozen (-20 degrees C): 3 months.

Notes

pH, fluid volume, and hydrogen ion concentration will be reported.

Ordering

Performed

Daily

Methodology

Ion selective electrode (ISE)

Reported

Same day

Synonyms

  • LAB3328
  • Gastric Fluid pH
Result Interpretation

Reference Interval

pH: 1.5 - 3.5

Hydrogen ion concentration: 0.39 - 39.60 mEq/L

Administrative

CPT Codes

83986

GASTRIN

LAB80

Collect

Serum separator tube.

Patient Preparation

Patient fast for 12 hours prior to collection is recommended.

Specimen Preparation

Transfer 1 mL serum to an ARUP Standard Transport Tube. (Min: 0.5 mL)

Unacceptable Conditions

Plasma, Tissue or Urine. Grossly hemolyzed or lipemic specimens.

Storage/Transport Temperature

Refrigerated.

Stability (from collection to initiation)

After separation from cells: Ambient: 8 hours; Refrigerated: 1 week; Frozen: 1 month

Performed

Sun-Sat

Methodology

Quantitative Chemiluminescent Immunoassay

Reported

1-2 days

Synonyms

  • LAB80

Ordering Recommendations

Aids in diagnosis of carcinoid and gastrinoma  tumors.

Reference Interval

0-100 pg/mL

CPT Codes

82941
Collection

LAB80

Collect

Serum separator tube.

Patient Preparation

Patient fast for 12 hours prior to collection is recommended.

Specimen Preparation

Transfer 1 mL serum to an ARUP Standard Transport Tube. (Min: 0.5 mL)

Unacceptable Conditions

Plasma, Tissue or Urine. Grossly hemolyzed or lipemic specimens.

Storage/Transport Temperature

Refrigerated.

Stability (from collection to initiation)

After separation from cells: Ambient: 8 hours; Refrigerated: 1 week; Frozen: 1 month
Ordering

Performed

Sun-Sat

Methodology

Quantitative Chemiluminescent Immunoassay

Reported

1-2 days

Synonyms

  • LAB80

Ordering Recommendations

Aids in diagnosis of carcinoid and gastrinoma  tumors.
Result Interpretation

Reference Interval

0-100 pg/mL
Administrative

CPT Codes

82941

GENITAL SCREENING CULTURE

Collect

Females-gynecological swabs (vagina, cervix, labia, vulva), males-urethral swabs

Unacceptable Conditions

Non genital sites or delayed transport.

Storage/Transport Temperature

Internal: Deliver to lab immediately
Offsite: Do not refrigerate. Transport to the laboratory on the same day.

Stability (from collection to initiation)

Transport to the lab immediately.

Remarks

Physician must specify suspected organism. Lab will identify: Yeast, Group B strep, Group A strep, Staph. aureus, Neisseria gonorrheae, Gardenrella vaginalis, actinomyces, etc. Appropriate sensitivity testing will be done only upon request.

Performed by

PCL Clinical Laboratory

Performed

Daily

Methodology

Aerobic culture

Reported

Varies

Performed by

PCL Clinical Laboratory

CPT Codes

87083
Collection

Collect

Females-gynecological swabs (vagina, cervix, labia, vulva), males-urethral swabs

Unacceptable Conditions

Non genital sites or delayed transport.

Storage/Transport Temperature

Internal: Deliver to lab immediately
Offsite: Do not refrigerate. Transport to the laboratory on the same day.

Stability (from collection to initiation)

Transport to the lab immediately.

Remarks

Physician must specify suspected organism. Lab will identify: Yeast, Group B strep, Group A strep, Staph. aureus, Neisseria gonorrheae, Gardenrella vaginalis, actinomyces, etc. Appropriate sensitivity testing will be done only upon request.

Performed by

PCL Clinical Laboratory
Ordering

Performed

Daily

Methodology

Aerobic culture

Reported

Varies
Result Interpretation

Performed by

PCL Clinical Laboratory
Administrative

CPT Codes

87083

GENOSURE NS3/4A - HEPATITIS C GENOSURE

LAB5198

Collect

Two 6.0 mL pink top tubes (EDTA)

Patient Preparation

Patient must have an HCV viral load >=2000 copies/mL.

Indicate HCV Genotype (1a, 1b only) with order.

Specimen Preparation

3.0 mL EDTA plasma needed

Unacceptable Conditions

Serum.

Nonfrozen samples.

Storage/Transport Temperature

Spin, separate and freeze plasma within 4 hours of collection.

Performed by

Monogram Biosciences in South San Francisco, CA.

Methodology

PCR amplification and DNA sequencing

Reported

Up to 3 weeks.

Synonyms

  • HCV GENOSURE
  • LAB5198

Reference Interval

HCV sensitive to antivirals Boceprevir, Simeprevir and Telaprevir.

Performed by

Monogram Biosciences in South San Francisco, CA.

CPT Codes

87900, 87902

Collection

LAB5198

Collect

Two 6.0 mL pink top tubes (EDTA)

Patient Preparation

Patient must have an HCV viral load >=2000 copies/mL.

Indicate HCV Genotype (1a, 1b only) with order.

Specimen Preparation

3.0 mL EDTA plasma needed

Unacceptable Conditions

Serum.

Nonfrozen samples.

Storage/Transport Temperature

Spin, separate and freeze plasma within 4 hours of collection.

Performed by

Monogram Biosciences in South San Francisco, CA.

Ordering

Methodology

PCR amplification and DNA sequencing

Reported

Up to 3 weeks.

Synonyms

  • HCV GENOSURE
  • LAB5198
Result Interpretation

Reference Interval

HCV sensitive to antivirals Boceprevir, Simeprevir and Telaprevir.

Performed by

Monogram Biosciences in South San Francisco, CA.

Administrative

CPT Codes

87900, 87902

GENTAMICIN PEAK

LAB28

GENT P

Collect

4.5 mL green top with gel (PST), plasma (lithium heparin).

Pediatric Collection

0.5 mL whole blood collected in a green top with gel Microtainer.

Unacceptable Conditions

Specimen not properly identified; incorrect container; insufficient sample volume; specimen thawed more than once.

Storage/Transport Temperature

Internal: Deliver to lab immediately.
Offsite: Separate serum or plasma from cells and store at 2-8 C if assayed within 24 hours. Freeze at -20 C if not assayed within 24 hours.

Stability (from collection to initiation)

24 hours at 2 -8 C.

Remarks

Draw gentamicin peak levels 30 minutes after the end of a 30 - 60 minute infusion.

Performed by

PCL Clinical Laboratory - Core Chemistry

Performed

Upon receipt

Methodology

Chemiluminescent immunoassay

Reported

Same day

Synonyms

  • Garamycin Peak
  • LAB28

Interpretive Data

REFERENCE RANGES
For Q8 dosing, peak levels should be 5-10 ug/mL.
For QD dosing peak levels are not necessary the majority of time, but should be >8 ug/mL.

Performed by

PCL Clinical Laboratory - Core Chemistry

CPT Codes

80170

Collection

LAB28

GENT P

Collect

4.5 mL green top with gel (PST), plasma (lithium heparin).

Pediatric Collection

0.5 mL whole blood collected in a green top with gel Microtainer.

Unacceptable Conditions

Specimen not properly identified; incorrect container; insufficient sample volume; specimen thawed more than once.

Storage/Transport Temperature

Internal: Deliver to lab immediately.
Offsite: Separate serum or plasma from cells and store at 2-8 C if assayed within 24 hours. Freeze at -20 C if not assayed within 24 hours.

Stability (from collection to initiation)

24 hours at 2 -8 C.

Remarks

Draw gentamicin peak levels 30 minutes after the end of a 30 - 60 minute infusion.

Performed by

PCL Clinical Laboratory - Core Chemistry

Ordering

Performed

Upon receipt

Methodology

Chemiluminescent immunoassay

Reported

Same day

Synonyms

  • Garamycin Peak
  • LAB28
Result Interpretation

Interpretive Data

REFERENCE RANGES
For Q8 dosing, peak levels should be 5-10 ug/mL.
For QD dosing peak levels are not necessary the majority of time, but should be >8 ug/mL.

Performed by

PCL Clinical Laboratory - Core Chemistry

Administrative

CPT Codes

80170

More Articles...