FIBRINOGEN

LAB314

FIB

Collect

One 2.7 mL blue top (3.2% citrate plasma).

Also acceptable: One 1.8 mL blue top tube (3.2% sodium citrate).

All blue top tubes collected for coagulation assays that do not have a blood culture collected first must have a discard tube collected prior to filling. The discard tube should be another blue top tube in which greater than 1 mL of blood is collected.

Pediatric Collection

0.5 mL platelet poor plasma.

Unacceptable Conditions

Clotted sample; tube fill volume less than 70% or greater than 110%; more than 4 hours since collection; sample not properly identified; incorrect container; insufficient sample volume.

Storage/Transport Temperature

Internal: Deliver to lab immediately at ambient temperature.
Offsite: Separate plasma from cells as soon as possible. Place plasma in an aliquot container and transport to lab frozen.

Stability (from collection to initiation)

Whole blood: Ambient, 4 hours.

Platelet poor plasma aliquot: Ambient, 4 hours; Refrigerated, 4 hours; Frozen (-20 degrees C), 2 weeks; Frozen (-70 degrees C), 6 months.

Performed by

PCL Clinical Laboratory - Coagulation

Performed

Daily

Methodology

Mechanical clot detection

Reported

Same day

Synonyms

  • LAB314
  • FIB

Reference Interval

150-400 mg/dL

Performed by

PCL Clinical Laboratory - Coagulation

CPT Codes

85384

Collection

LAB314

FIB

Collect

One 2.7 mL blue top (3.2% citrate plasma).

Also acceptable: One 1.8 mL blue top tube (3.2% sodium citrate).

All blue top tubes collected for coagulation assays that do not have a blood culture collected first must have a discard tube collected prior to filling. The discard tube should be another blue top tube in which greater than 1 mL of blood is collected.

Pediatric Collection

0.5 mL platelet poor plasma.

Unacceptable Conditions

Clotted sample; tube fill volume less than 70% or greater than 110%; more than 4 hours since collection; sample not properly identified; incorrect container; insufficient sample volume.

Storage/Transport Temperature

Internal: Deliver to lab immediately at ambient temperature.
Offsite: Separate plasma from cells as soon as possible. Place plasma in an aliquot container and transport to lab frozen.

Stability (from collection to initiation)

Whole blood: Ambient, 4 hours.

Platelet poor plasma aliquot: Ambient, 4 hours; Refrigerated, 4 hours; Frozen (-20 degrees C), 2 weeks; Frozen (-70 degrees C), 6 months.

Performed by

PCL Clinical Laboratory - Coagulation

Ordering

Performed

Daily

Methodology

Mechanical clot detection

Reported

Same day

Synonyms

  • LAB314
  • FIB
Result Interpretation

Reference Interval

150-400 mg/dL

Performed by

PCL Clinical Laboratory - Coagulation

Administrative

CPT Codes

85384

FIBROBLAST GROWTH FACTOR 23 - PLASMA

LAB4687

Collect

5.0 mL Purple Top Tube

Specimen Preparation

1.5 mL EDTA plasma

Pediatric Collection

0.5 mL EDTA plasma

Unacceptable Conditions

Ambient temperature. Serum.

Storage/Transport Temperature

Spin/Separate and ship to PCL lab on Dry Ice.

Performed by

Mayo Medical Laboratories

Performed

Tuesdays @ Mayo

Methodology

Immunometric Enzyme Assay

Reported

2-10 days

Synonyms

  • FGF23

Reference Interval

0-3 months:   Not established

3 months - 17 years: <230 RU/mL

>17 years:                <180 RU/mL

Performed by

Mayo Medical Laboratories

CPT Codes

83520

Collection

LAB4687

Collect

5.0 mL Purple Top Tube

Specimen Preparation

1.5 mL EDTA plasma

Pediatric Collection

0.5 mL EDTA plasma

Unacceptable Conditions

Ambient temperature. Serum.

Storage/Transport Temperature

Spin/Separate and ship to PCL lab on Dry Ice.

Performed by

Mayo Medical Laboratories

Ordering

Performed

Tuesdays @ Mayo

Methodology

Immunometric Enzyme Assay

Reported

2-10 days

Synonyms

  • FGF23
Result Interpretation

Reference Interval

0-3 months:   Not established

3 months - 17 years: <230 RU/mL

>17 years:                <180 RU/mL

Performed by

Mayo Medical Laboratories

Administrative

CPT Codes

83520

Fine Needle Aspirate (FNA) - Parathyroid Hormone

Collect

Collect 1 mL of sterile needle washout into a sterile container.

Unacceptable Conditions

Specimen not properly identified; incorrect container; insufficient sample volume; specimen thawed more than once.

Storage/Transport Temperature

Internal: Deliver to lab immediately at ambient temperature or on cold pack.

Offsite: Deliver to lab at 2-8 degrees C if tested within 48 hours. Send frozen if shipping delay is anticipated to be greater than 48 hours.

Stability (from collection to initiation)

Ambient: 4 hours, Refrigerated: 48 hours, Frozen (-20 degrees C): 6 months.

Performed by

PCL Clinical Laboratory - Core Chemistry

Performed

Upon receipt

Methodology

Chemiluminescent Immunoassay

Reported

Same day

Interpretive Data

Test results obtained on nonstandard specimens (fine needle aspiration washing) must be interpreted with caution. Reference ranges do not apply for this specimen type.

Performed by

PCL Clinical Laboratory - Core Chemistry

CPT Codes

83970
Collection

Collect

Collect 1 mL of sterile needle washout into a sterile container.

Unacceptable Conditions

Specimen not properly identified; incorrect container; insufficient sample volume; specimen thawed more than once.

Storage/Transport Temperature

Internal: Deliver to lab immediately at ambient temperature or on cold pack.

Offsite: Deliver to lab at 2-8 degrees C if tested within 48 hours. Send frozen if shipping delay is anticipated to be greater than 48 hours.

Stability (from collection to initiation)

Ambient: 4 hours, Refrigerated: 48 hours, Frozen (-20 degrees C): 6 months.

Performed by

PCL Clinical Laboratory - Core Chemistry
Ordering

Performed

Upon receipt

Methodology

Chemiluminescent Immunoassay

Reported

Same day
Result Interpretation

Interpretive Data

Test results obtained on nonstandard specimens (fine needle aspiration washing) must be interpreted with caution. Reference ranges do not apply for this specimen type.

Performed by

PCL Clinical Laboratory - Core Chemistry
Administrative

CPT Codes

83970

Fine Needle Aspirate (FNA) - Thyroglobulin Panel

LAB3371

Collect

Collect 1 mL of sterile needle washout into a sterile container.

Unacceptable Conditions

Specimen not properly identified; incorrect container; insufficient sample volume; specimen thawed more than once.

Storage/Transport Temperature

Internal: Deliver to lab immediately at ambient temperature or on cold pack.

Offsite: Deliver to lab at 2-8 degrees C if delivered within 48 hours. Send frozen if shipping delay is anticipated to be greater than 48 hours.

Stability (from collection to initiation)

Ambient: 8 hours, Refrigerated: 48 hours, Frozen (-20 degrees C): Indefinitely.

Remarks

FNA TGLOB test includes FNA THYROGLOBULIN and FNA THY AB assays.

Performed by

PCL Clinical Laboratory - Core Chemistry

Performed

Upon receipt

Methodology

Chemiluminescent Immunoassay

Reported

Same day

Synonyms

  • LAB3371

Interpretive Data

Test results obtained on nonstandard specimens (fine needle aspiration washing) must be interpreted with caution. Reference ranges do not apply for this specimen type.

FNA thyroglobulin value accuracy is suspect in the presence of FNA Anti-thyroglobulin values greater than 60 U/mL.

Performed by

PCL Clinical Laboratory - Core Chemistry

CPT Codes

84432, 86800

Collection

LAB3371

Collect

Collect 1 mL of sterile needle washout into a sterile container.

Unacceptable Conditions

Specimen not properly identified; incorrect container; insufficient sample volume; specimen thawed more than once.

Storage/Transport Temperature

Internal: Deliver to lab immediately at ambient temperature or on cold pack.

Offsite: Deliver to lab at 2-8 degrees C if delivered within 48 hours. Send frozen if shipping delay is anticipated to be greater than 48 hours.

Stability (from collection to initiation)

Ambient: 8 hours, Refrigerated: 48 hours, Frozen (-20 degrees C): Indefinitely.

Remarks

FNA TGLOB test includes FNA THYROGLOBULIN and FNA THY AB assays.

Performed by

PCL Clinical Laboratory - Core Chemistry

Ordering

Performed

Upon receipt

Methodology

Chemiluminescent Immunoassay

Reported

Same day

Synonyms

  • LAB3371
Result Interpretation

Interpretive Data

Test results obtained on nonstandard specimens (fine needle aspiration washing) must be interpreted with caution. Reference ranges do not apply for this specimen type.

FNA thyroglobulin value accuracy is suspect in the presence of FNA Anti-thyroglobulin values greater than 60 U/mL.

Performed by

PCL Clinical Laboratory - Core Chemistry

Administrative

CPT Codes

84432, 86800

FLECAINIDE

LAB687

 

Collect

Plain red. Also acceptable: Lavender (EDTA), pink (K2EDTA or K3EDTA), green (sodium or lithium heparin), or gray (sodium fluoride/potassium oxalate).

Patient Preparation

Timing of specimen collection: Pre-dose (trough) draw - At steady state concentration.

Specimen Preparation

Separate serum or plasma from cells within 6 hours of collection. Transfer 2 mL serum to an ARUP Standard Transport Tube. (Min: 0.5 mL)

Unacceptable Conditions

Gel separator tubes or gels of any kind; drug loss is immediate and no testing will be performed.

Storage/Transport Temperature

Refrigerated.

Stability (from collection to initiation)

After separation from cells: Ambient: 6 weeks; Refrigerated: 6 weeks; Frozen: 6 weeks

Performed

Tue, Thu, Sat

Methodology

Quantitative Liquid Chromatography-Tandem Mass Spectrometry

Reported

1-5 days

Synonyms

  • Tambocor
  • LAB687

Ordering Recommendations

Optimize drug therapy and monitor patient adherence.

Reference Interval

Therapeutic Range:
0.20-1.00 µg/mL
Toxic: > 1.50 µg/mL

Interpretive Data

Toxic concentrations may cause cardiac abnormalities, hypotension and seizure.

CPT Codes

80299
Collection

LAB687

 

Collect

Plain red. Also acceptable: Lavender (EDTA), pink (K2EDTA or K3EDTA), green (sodium or lithium heparin), or gray (sodium fluoride/potassium oxalate).

Patient Preparation

Timing of specimen collection: Pre-dose (trough) draw - At steady state concentration.

Specimen Preparation

Separate serum or plasma from cells within 6 hours of collection. Transfer 2 mL serum to an ARUP Standard Transport Tube. (Min: 0.5 mL)

Unacceptable Conditions

Gel separator tubes or gels of any kind; drug loss is immediate and no testing will be performed.

Storage/Transport Temperature

Refrigerated.

Stability (from collection to initiation)

After separation from cells: Ambient: 6 weeks; Refrigerated: 6 weeks; Frozen: 6 weeks
Ordering

Performed

Tue, Thu, Sat

Methodology

Quantitative Liquid Chromatography-Tandem Mass Spectrometry

Reported

1-5 days

Synonyms

  • Tambocor
  • LAB687

Ordering Recommendations

Optimize drug therapy and monitor patient adherence.
Result Interpretation

Reference Interval

Therapeutic Range:
0.20-1.00 µg/mL
Toxic: > 1.50 µg/mL

Interpretive Data

Toxic concentrations may cause cardiac abnormalities, hypotension and seizure.

Administrative

CPT Codes

80299

FLT3 GENE MUTATIONS BY PCR

LAB4382

 

Collect

3 mL EDTA whole blood or bone marrow

Unacceptable Conditions

Serum/plasma. Frozen samples.

Storage/Transport Temperature

Ambient: 5 days

Refreigerated:  Acceptable but not preferred

Performed by

Children's Hospital Colorado in Aurora, CO.

Performed

2 days a week

Methodology

PCR

Reported

7-10 days

Synonyms

  • LAB4382
  • FLT3
  • FLT3PCR

Reference Interval

No molecular evidence for the FLT3 gene mutations (ITD and D835)

Performed by

Children's Hospital Colorado in Aurora, CO.

CPT Codes

81245, 81479

Collection

LAB4382

 

Collect

3 mL EDTA whole blood or bone marrow

Unacceptable Conditions

Serum/plasma. Frozen samples.

Storage/Transport Temperature

Ambient: 5 days

Refreigerated:  Acceptable but not preferred

Performed by

Children's Hospital Colorado in Aurora, CO.

Ordering

Performed

2 days a week

Methodology

PCR

Reported

7-10 days

Synonyms

  • LAB4382
  • FLT3
  • FLT3PCR
Result Interpretation

Reference Interval

No molecular evidence for the FLT3 gene mutations (ITD and D835)

Performed by

Children's Hospital Colorado in Aurora, CO.

Administrative

CPT Codes

81245, 81479

FOLATE

LAB69

FOLATE

Collect

One 4.5 mL Green top tube with gel separator (PST)

 

 

Pediatric Collection

Minimum volume: 1.5 mL blood

Unacceptable Conditions

Sample not properly identified, insufficient sample volume, incorrect container.

Storage/Transport Temperature

Internal: Deliver to lab immediately. Protect from light.
Offsite: Centrifuge within 30 minutes of collection, transport refrigerated.

Stability (from collection to initiation)

Refrigerated: 8 hours; Frozen: 1 month

Remarks

Patient should be fasting.

Performed by

PCL Clinical Laboratory - CORE

Performed

Daily

Methodology

Chemiluminescent immunoassay.

Reported

Daily

Synonyms

  • LAB69
  • FOLIC ACID

Reference Interval

>5.9 ng/mL

 

 

 

Interpretive Data

The WHO Technical Consultation on folate and vitamin B12 deficiencies has determined that deficient folate concentrations are considered to be less than 4 ng/mL.

Performed by

PCL Clinical Laboratory - CORE

CPT Codes

82746

Collection

LAB69

FOLATE

Collect

One 4.5 mL Green top tube with gel separator (PST)

 

 

Pediatric Collection

Minimum volume: 1.5 mL blood

Unacceptable Conditions

Sample not properly identified, insufficient sample volume, incorrect container.

Storage/Transport Temperature

Internal: Deliver to lab immediately. Protect from light.
Offsite: Centrifuge within 30 minutes of collection, transport refrigerated.

Stability (from collection to initiation)

Refrigerated: 8 hours; Frozen: 1 month

Remarks

Patient should be fasting.

Performed by

PCL Clinical Laboratory - CORE

Ordering

Performed

Daily

Methodology

Chemiluminescent immunoassay.

Reported

Daily

Synonyms

  • LAB69
  • FOLIC ACID
Result Interpretation

Reference Interval

>5.9 ng/mL

 

 

 

Interpretive Data

The WHO Technical Consultation on folate and vitamin B12 deficiencies has determined that deficient folate concentrations are considered to be less than 4 ng/mL.

Performed by

PCL Clinical Laboratory - CORE

Administrative

CPT Codes

82746

FOLLICLE STIMULATING HORMONE

LAB86

FSH

Collect

One 4.5 mL Gold top tube with gel separator, clot activator serum.

Pediatric Collection

Minimum volume: 1.5 mL blood

Unacceptable Conditions

Specimen not properly identified; incorrect container; insufficient sample volume.

Storage/Transport Temperature

Internal: Deliver to lab immediately.
Offsite: Allow samples to clot 30 minutes before centrifugation. Keep tubes stoppered at all times. Centrifuge to separate cells from serum. Transport to Laboratory refrigerated.

Stability (from collection to initiation)

After centrifugation:

Ambient, 8 hours; Refrigerated, 2 days; Frozen, Unacceptable

Serum aliquot:

Ambient, 8 hours; Refrigerated, 2 days; Frozen (-20 degrees C), Unknown.

Samples that have been thawed and refrozen are not suitable for FSH analysis.

Performed by

PCL Clinical Laboratory - Core

Performed

Daily

Methodology

Indirect ISE

Reported

Daily

Synonyms

  • LAB86
  • FSH

Interpretive Data

Reporting units mIU/mL

Females – normally menstruating

Follicular phase 2-10

Midcycle peak 3-33

Luteal phase 2-9

Pregnant female <1

Males 13-70 years 1-18

Performed by

PCL Clinical Laboratory - Core

CPT Codes

83001

Collection

LAB86

FSH

Collect

One 4.5 mL Gold top tube with gel separator, clot activator serum.

Pediatric Collection

Minimum volume: 1.5 mL blood

Unacceptable Conditions

Specimen not properly identified; incorrect container; insufficient sample volume.

Storage/Transport Temperature

Internal: Deliver to lab immediately.
Offsite: Allow samples to clot 30 minutes before centrifugation. Keep tubes stoppered at all times. Centrifuge to separate cells from serum. Transport to Laboratory refrigerated.

Stability (from collection to initiation)

After centrifugation:

Ambient, 8 hours; Refrigerated, 2 days; Frozen, Unacceptable

Serum aliquot:

Ambient, 8 hours; Refrigerated, 2 days; Frozen (-20 degrees C), Unknown.

Samples that have been thawed and refrozen are not suitable for FSH analysis.

Performed by

PCL Clinical Laboratory - Core

Ordering

Performed

Daily

Methodology

Indirect ISE

Reported

Daily

Synonyms

  • LAB86
  • FSH
Result Interpretation

Interpretive Data

Reporting units mIU/mL

Females – normally menstruating

Follicular phase 2-10

Midcycle peak 3-33

Luteal phase 2-9

Pregnant female <1

Males 13-70 years 1-18

Performed by

PCL Clinical Laboratory - Core

Administrative

CPT Codes

83001

FONDAPARINUX ANTI-XA LEVEL

LAB3128

Collect

One 2.7 mL Blue top tube (sodium citrate 3.2%).

Pediatric Collection

Tubes must be filled to 80-100% capacity; or 0.5 mL of platelet poor plasma.

Unacceptable Conditions

Sample not properly identified; incorrect container; insufficient sample volume; clotted sample; hemolysed sample; tubes not filled to 80-100% capacity

Storage/Transport Temperature

Internal: Deliver to lab immediately.
Offsite: Transport to laboratory at ambient temperature if within 1 hour of collection. If transport is delayed outside of ambient temperature stability guidelines, centrifuge the sample to obtain platelet-poor plasma. Place plasma in aliquot tube (1.0 mL platelet-poor plasma) and send frozen.

Stability (from collection to initiation)

Plasma- Ambient: 2 hours; Refrigerated: 4 hours; Frozen (-20 degrees C): 1 month

Performed by

LABCorp - Esoterix Coagulation

Notes

Use: Monitor prophylactic fondaparanux (Arixtra) levels in patient serum.

Synonyms

  • ARIXTRA LEVEL
  • LAB3128

Reference Interval

<0.39 mg/L

Prophylactic Range: 0.39-0.50 mg/L

Performed by

LABCorp - Esoterix Coagulation

CPT Codes

85520

Collection

LAB3128

Collect

One 2.7 mL Blue top tube (sodium citrate 3.2%).

Pediatric Collection

Tubes must be filled to 80-100% capacity; or 0.5 mL of platelet poor plasma.

Unacceptable Conditions

Sample not properly identified; incorrect container; insufficient sample volume; clotted sample; hemolysed sample; tubes not filled to 80-100% capacity

Storage/Transport Temperature

Internal: Deliver to lab immediately.
Offsite: Transport to laboratory at ambient temperature if within 1 hour of collection. If transport is delayed outside of ambient temperature stability guidelines, centrifuge the sample to obtain platelet-poor plasma. Place plasma in aliquot tube (1.0 mL platelet-poor plasma) and send frozen.

Stability (from collection to initiation)

Plasma- Ambient: 2 hours; Refrigerated: 4 hours; Frozen (-20 degrees C): 1 month

Performed by

LABCorp - Esoterix Coagulation

Notes

Use: Monitor prophylactic fondaparanux (Arixtra) levels in patient serum.

Ordering

Synonyms

  • ARIXTRA LEVEL
  • LAB3128
Result Interpretation

Reference Interval

<0.39 mg/L

Prophylactic Range: 0.39-0.50 mg/L

Performed by

LABCorp - Esoterix Coagulation

Administrative

CPT Codes

85520

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