ANTI-FUNGAL DRUG LEVEL

Collect

One 6 mL plain red or1mL body fluid.

Storage/Transport Temperature

Internal: Deliver to lab immediatley
Offsite: 2 mL blood, 1 mL body fluid. Separate serum from cells and deliver to the lab frozen.

Remarks

Freeze specimen.

Performed by

PCL Clinical Laboratory

Performed

Tue, Thu

Methodology

Bioassay, HPLC, GLC

Reported

In 2 days

Performed by

PCL Clinical Laboratory
Collection

Collect

One 6 mL plain red or1mL body fluid.

Storage/Transport Temperature

Internal: Deliver to lab immediatley
Offsite: 2 mL blood, 1 mL body fluid. Separate serum from cells and deliver to the lab frozen.

Remarks

Freeze specimen.

Performed by

PCL Clinical Laboratory
Ordering

Performed

Tue, Thu

Methodology

Bioassay, HPLC, GLC

Reported

In 2 days
Result Interpretation

Performed by

PCL Clinical Laboratory
Administrative

ANTI-HISTONE ANTIBODY

LAB3111

Collect

5.0 mL, gold or red top with gel (SST), (clot activator serum).

Unacceptable Conditions

Excessive hemolysis, chylous serum, gross contamination, inadequate volume of blood, inadequate patient and/or specimen identification.

Storage/Transport Temperature

Internal: Deliver to lab immediately
Offsite: 2 mL Separate serum from cells and deliver to the lab refrigerated.

Stability (from collection to initiation)

Refrigerated: 1-2 weeks; Frozen: Indefinitely.

Remarks

Serum must be removed from clot within 2 hours; refrigerate.

Performed by

PCL Clinical Laboratory

Performed

Bi-Monthly

Methodology

Enzyme-linked immunosorbent assay [ELISA].

Reported

Same day

Synonyms

  • -377 Anti-Histone Antibody
  • LAB3111

Reference Interval

Negative

Performed by

PCL Clinical Laboratory

CPT Codes

86235

Collection

LAB3111

Collect

5.0 mL, gold or red top with gel (SST), (clot activator serum).

Unacceptable Conditions

Excessive hemolysis, chylous serum, gross contamination, inadequate volume of blood, inadequate patient and/or specimen identification.

Storage/Transport Temperature

Internal: Deliver to lab immediately
Offsite: 2 mL Separate serum from cells and deliver to the lab refrigerated.

Stability (from collection to initiation)

Refrigerated: 1-2 weeks; Frozen: Indefinitely.

Remarks

Serum must be removed from clot within 2 hours; refrigerate.

Performed by

PCL Clinical Laboratory

Ordering

Performed

Bi-Monthly

Methodology

Enzyme-linked immunosorbent assay [ELISA].

Reported

Same day

Synonyms

  • -377 Anti-Histone Antibody
  • LAB3111
Result Interpretation

Reference Interval

Negative

Performed by

PCL Clinical Laboratory

Administrative

CPT Codes

86235

ANTI-JO1 ANTIBODY

LAB770

Collect

One 7 ml red top with gel

Unacceptable Conditions

Excessive hemolysis, chylous serum, gross contamination, inadequate volume of blood, inadequate patient and/or specimen identification.

Storage/Transport Temperature

Internal: Deliver to lab immediately
Offsite: 2 mL serum Separate serum from cells and deliver to the lab refrigerated.

Stability (from collection to initiation)

Refrigerated: 1-2 weeks; Frozen: Indefinitely.

Remarks

Remove serum from clot within 2 hours after drawing. Refrigerate specimen.

Performed by

PCL Clinical Laboratory

Performed

Upon receipt

Methodology

Immunodliflusion [ID]

Reported

In 2 days

Synonyms

  • -378 Anti-JO1 Antibody
  • LAB770

Reference Interval

NEGATIVE

Interpretive Data

REFERENCE NOTE: Anti-JO1 is present in 25% of patients with polymyositis/
dermatomyositis.

Performed by

PCL Clinical Laboratory

CPT Codes

86235

Collection

LAB770

Collect

One 7 ml red top with gel

Unacceptable Conditions

Excessive hemolysis, chylous serum, gross contamination, inadequate volume of blood, inadequate patient and/or specimen identification.

Storage/Transport Temperature

Internal: Deliver to lab immediately
Offsite: 2 mL serum Separate serum from cells and deliver to the lab refrigerated.

Stability (from collection to initiation)

Refrigerated: 1-2 weeks; Frozen: Indefinitely.

Remarks

Remove serum from clot within 2 hours after drawing. Refrigerate specimen.

Performed by

PCL Clinical Laboratory

Ordering

Performed

Upon receipt

Methodology

Immunodliflusion [ID]

Reported

In 2 days

Synonyms

  • -378 Anti-JO1 Antibody
  • LAB770
Result Interpretation

Reference Interval

NEGATIVE

Interpretive Data

REFERENCE NOTE: Anti-JO1 is present in 25% of patients with polymyositis/
dermatomyositis.

Performed by

PCL Clinical Laboratory

Administrative

CPT Codes

86235

ANTI-LIVER-KIDNEY MICROSOME AB

LAB3085

Collect

Serum separator tube.

Specimen Preparation

Transfer 1 mL serum to an ARUP Standard Transport Tube. (Min: 0.15 mL)

Unacceptable Conditions

Severely hemolyzed or lipemic specimens.

Storage/Transport Temperature

Refrigerated.

Stability (from collection to initiation)

After separation from cells: Ambient: 48 hours; Refrigerated: 2 weeks; Frozen: 1 year (avoid repeated freeze/thaw cycles)

Performed

Mon-Sat

Methodology

Semi-Quantitative Indirect Fluorescent Antibody

Reported

1-5 days

Synonyms

  • LKM ANTIBODY
  • LIVER-KIDNEY-MICROSOMAL AB
  • LAB3085
  • LIVER-KID

Additional Technical Information

Ordering Recommendations

Differential evaluation of autoimmune liver disease of unknown etiology, especially autoimmune hepatitis (AIH) of childhood onset. Use in combination with IgG testing for type1 liver cystolic antigen (2010711) when evaluating for AIH-2.

Reference Interval

Less than 1:20 Normal

Interpretive Data

Liver-Kidney Microsome IgG antibody (anti-LKM), as detected by indirect immunofluorescent antibody (IFA) techniques, may be observed in patients with autoimmune hepatitis type 2 (AIH-2), AIH-2 associated with autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy (APECED), viral hepatitis C or D, and some forms of drug-induced hepatitis. This IFA does not differentiate among the four types of LKM antibodies (LKM-1, LKM-2, LKM-3, and a fourth type that recognizes CYP1A2 and CYP2A6 antigens). Of these, anti-LKM-1 (cytochrome P450IID6) IgG antibodies are considered specific for AIH-2.

CPT Codes

86376
Collection

LAB3085

Collect

Serum separator tube.

Specimen Preparation

Transfer 1 mL serum to an ARUP Standard Transport Tube. (Min: 0.15 mL)

Unacceptable Conditions

Severely hemolyzed or lipemic specimens.

Storage/Transport Temperature

Refrigerated.

Stability (from collection to initiation)

After separation from cells: Ambient: 48 hours; Refrigerated: 2 weeks; Frozen: 1 year (avoid repeated freeze/thaw cycles)
Ordering

Performed

Mon-Sat

Methodology

Semi-Quantitative Indirect Fluorescent Antibody

Reported

1-5 days

Synonyms

  • LKM ANTIBODY
  • LIVER-KIDNEY-MICROSOMAL AB
  • LAB3085
  • LIVER-KID

Additional Technical Information

Ordering Recommendations

Differential evaluation of autoimmune liver disease of unknown etiology, especially autoimmune hepatitis (AIH) of childhood onset. Use in combination with IgG testing for type1 liver cystolic antigen (2010711) when evaluating for AIH-2.
Result Interpretation

Reference Interval

Less than 1:20 Normal

Interpretive Data

Liver-Kidney Microsome IgG antibody (anti-LKM), as detected by indirect immunofluorescent antibody (IFA) techniques, may be observed in patients with autoimmune hepatitis type 2 (AIH-2), AIH-2 associated with autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy (APECED), viral hepatitis C or D, and some forms of drug-induced hepatitis. This IFA does not differentiate among the four types of LKM antibodies (LKM-1, LKM-2, LKM-3, and a fourth type that recognizes CYP1A2 and CYP2A6 antigens). Of these, anti-LKM-1 (cytochrome P450IID6) IgG antibodies are considered specific for AIH-2.

Administrative

CPT Codes

86376

ANTI-MITOCHONDRIAL ANTIBODY

LAB513

Collect

One 7 ml red top with gel

Unacceptable Conditions

Excessive hemolysis, chylous serum, gross contamination, inadequate volume of blood, inadequate patient and/or specimen identification.

Storage/Transport Temperature

Internal: Deliver to lab immediately
Offsite: 2 mL serum Separate serum from cells and deliver to the lab refrigerated.

Stability (from collection to initiation)

Refrigerated: 2-3 weeks; Frozen: Indefinitely.

Remarks

Separate serum and refrigerate specimen if it cannot be processed immediately. Limitations: 1. Presence of antinuclear antibody may interfere with the interpretation of smooth muscle antibody, 2. If AMA is positive, unable to demonstrate anti-parietal cell.

Performed by

PCL Clinical Laboratory

Performed

Mon - Fri

Methodology

Indirect fluorescent antibody (IFA) using mouse kidney substrate.

Reported

In 14 days

Synonyms

  • -379 Anti-Mitochondrial Antibody

Reference Interval

NEGATIVE

Performed by

PCL Clinical Laboratory

CPT Codes

86255 if negative; if postiive add 86256 (titer)

Collection

LAB513

Collect

One 7 ml red top with gel

Unacceptable Conditions

Excessive hemolysis, chylous serum, gross contamination, inadequate volume of blood, inadequate patient and/or specimen identification.

Storage/Transport Temperature

Internal: Deliver to lab immediately
Offsite: 2 mL serum Separate serum from cells and deliver to the lab refrigerated.

Stability (from collection to initiation)

Refrigerated: 2-3 weeks; Frozen: Indefinitely.

Remarks

Separate serum and refrigerate specimen if it cannot be processed immediately. Limitations: 1. Presence of antinuclear antibody may interfere with the interpretation of smooth muscle antibody, 2. If AMA is positive, unable to demonstrate anti-parietal cell.

Performed by

PCL Clinical Laboratory

Ordering

Performed

Mon - Fri

Methodology

Indirect fluorescent antibody (IFA) using mouse kidney substrate.

Reported

In 14 days

Synonyms

  • -379 Anti-Mitochondrial Antibody
Result Interpretation

Reference Interval

NEGATIVE

Performed by

PCL Clinical Laboratory

Administrative

CPT Codes

86255 if negative; if postiive add 86256 (titer)

ANTI-MULLERIAN HORMONE

LAB1733

Collect

Serum separator tube. Also acceptable: Plain red or green (lithium heparin).

Specimen Preparation

Separate from cells ASAP or within 2 hours of collection. Transfer 0.5 mL serum to an ARUP Standard Transport Tube. (Min: 0.2 mL)

Unacceptable Conditions

Hemolyzed or lipemic specimens.

Storage/Transport Temperature

Frozen.

Stability (from collection to initiation)

Ambient: Unacceptable; Refrigerated: 1 week; Frozen: 3 weeks (avoid repeated freeze/thaw cycles)

Performed

Sun-Sat

Methodology

Quantitative Enzyme-Linked Immunosorbent Assay

Reported

1-3 days

Synonyms

  • Mullerian Inhibiting Substance
  • AMH
  • LAB1733

Reference Interval

Effective April 7, 2014
FemaleMale
AgeReference IntervalAgeReference Interval
6 months - 14 years0.256-6.345 ng/mL6-11 months56.677-495.299 ng/mL
15-17 years0.861-10.451 ng/mL1-6 years33.442-342.450 ng/ml
18-29 years0.401-16.015 ng/mL7-9 years20.245-189.781 ng/mL
30-39 years0.176-11.705 ng/mL10-12 years2.903-178.243 ng/mL
40-45 years6.282 ng/mL or less13 years or greater2.079-30.656 ng/mL
46-50 years0.064 ng/mL or less
Post-menopausal0.003 ng/mL or less

CPT Codes

83520
Collection

LAB1733

Collect

Serum separator tube. Also acceptable: Plain red or green (lithium heparin).

Specimen Preparation

Separate from cells ASAP or within 2 hours of collection. Transfer 0.5 mL serum to an ARUP Standard Transport Tube. (Min: 0.2 mL)

Unacceptable Conditions

Hemolyzed or lipemic specimens.

Storage/Transport Temperature

Frozen.

Stability (from collection to initiation)

Ambient: Unacceptable; Refrigerated: 1 week; Frozen: 3 weeks (avoid repeated freeze/thaw cycles)
Ordering

Performed

Sun-Sat

Methodology

Quantitative Enzyme-Linked Immunosorbent Assay

Reported

1-3 days

Synonyms

  • Mullerian Inhibiting Substance
  • AMH
  • LAB1733
Result Interpretation

Reference Interval

Effective April 7, 2014
FemaleMale
AgeReference IntervalAgeReference Interval
6 months - 14 years0.256-6.345 ng/mL6-11 months56.677-495.299 ng/mL
15-17 years0.861-10.451 ng/mL1-6 years33.442-342.450 ng/ml
18-29 years0.401-16.015 ng/mL7-9 years20.245-189.781 ng/mL
30-39 years0.176-11.705 ng/mL10-12 years2.903-178.243 ng/mL
40-45 years6.282 ng/mL or less13 years or greater2.079-30.656 ng/mL
46-50 years0.064 ng/mL or less
Post-menopausal0.003 ng/mL or less

Administrative

CPT Codes

83520

ANTI-NEUTROPHIL CYTO ABS-POS

LAB3470

Collect

One 7 ml red top with gel

Unacceptable Conditions

Excessive hemolysis, chylous serum, gross contamination, inadequate volume of blood, inadequate patient identification and/or specimen identification.

Storage/Transport Temperature

Internal: Deliver to lab immediately
Offsite: 2 mL serum Separate serum from cells and deliver to lab refrigerated.
Remove serum from clot within 2 hours after drawing. Refrigerate specimen.

Stability (from collection to initiation)

Refrigerated: 1-2 weeks; Frozen: Indefinitely.

Remarks

This test includes c-ANCA and p-ANCA with reflex to titer and PR3AB or MPOAB.

Performed by

PCL Clinical Laboratory

Performed

2 times per week

Methodology

Immunofluorescence on ETOH and formalin fixed human neutrophils. Panca-positive samples are further analyzed using an MPO-specific ELISA; Canca-positive samples re further analyzed using a PR3 specific ELISA.

Reported

In 7 days

Synonyms

  • -772 ANCA Positive with reflex to titer & MPOAB or PR3AB
  • LAB3470

Reference Interval

c-ANCA: Negative

p-ANCA: Negative

Performed by

PCL Clinical Laboratory

CPT Codes

86255 c-ANCA; if positive add 86256; 86255 p-ANCA, if positive add 86256; 83876 MPO; 83520 PR3

Collection

LAB3470

Collect

One 7 ml red top with gel

Unacceptable Conditions

Excessive hemolysis, chylous serum, gross contamination, inadequate volume of blood, inadequate patient identification and/or specimen identification.

Storage/Transport Temperature

Internal: Deliver to lab immediately
Offsite: 2 mL serum Separate serum from cells and deliver to lab refrigerated.
Remove serum from clot within 2 hours after drawing. Refrigerate specimen.

Stability (from collection to initiation)

Refrigerated: 1-2 weeks; Frozen: Indefinitely.

Remarks

This test includes c-ANCA and p-ANCA with reflex to titer and PR3AB or MPOAB.

Performed by

PCL Clinical Laboratory

Ordering

Performed

2 times per week

Methodology

Immunofluorescence on ETOH and formalin fixed human neutrophils. Panca-positive samples are further analyzed using an MPO-specific ELISA; Canca-positive samples re further analyzed using a PR3 specific ELISA.

Reported

In 7 days

Synonyms

  • -772 ANCA Positive with reflex to titer & MPOAB or PR3AB
  • LAB3470
Result Interpretation

Reference Interval

c-ANCA: Negative

p-ANCA: Negative

Performed by

PCL Clinical Laboratory

Administrative

CPT Codes

86255 c-ANCA; if positive add 86256; 86255 p-ANCA, if positive add 86256; 83876 MPO; 83520 PR3

ANTI-PARIETAL CELL ANTIBODY

LAB514

Collect

5.0 mL, gold or red top with gel (SST), (clot activator serum).

Unacceptable Conditions

Excessive hemolysis, chylous serum, gross contamination, inadequate volume of blood, inadequate patient and/or specimen identification.

Storage/Transport Temperature

Internal: Deliver to lab immediately
Offsite: 2 mL Separate serum from cells and deliver to the lab refrigerated.

Stability (from collection to initiation)

Refrigerated: 2-3 weeks; Frozen: Indefinitely.

Remarks

Remove serum from clot within 2 hours after drawing. Refrigerate specimen. Limitations: 1. Presence of antinuclear antibody may interfere with the interpretation of smooth muscle antibody, 2. If AMA is positive, unable to demonstrate anti-parietal cell.

Performed by

PCL Clinical Laboratory

Performed

Mon - Fri

Methodology

Indirect immunofluorescence using mouse stomach tissue.

Reported

In 14 days

Reference Interval

NEGATIVE

Performed by

PCL Clinical Laboratory

CPT Codes

86255

Collection

LAB514

Collect

5.0 mL, gold or red top with gel (SST), (clot activator serum).

Unacceptable Conditions

Excessive hemolysis, chylous serum, gross contamination, inadequate volume of blood, inadequate patient and/or specimen identification.

Storage/Transport Temperature

Internal: Deliver to lab immediately
Offsite: 2 mL Separate serum from cells and deliver to the lab refrigerated.

Stability (from collection to initiation)

Refrigerated: 2-3 weeks; Frozen: Indefinitely.

Remarks

Remove serum from clot within 2 hours after drawing. Refrigerate specimen. Limitations: 1. Presence of antinuclear antibody may interfere with the interpretation of smooth muscle antibody, 2. If AMA is positive, unable to demonstrate anti-parietal cell.

Performed by

PCL Clinical Laboratory

Ordering

Performed

Mon - Fri

Methodology

Indirect immunofluorescence using mouse stomach tissue.

Reported

In 14 days

Result Interpretation

Reference Interval

NEGATIVE

Performed by

PCL Clinical Laboratory

Administrative

CPT Codes

86255

ANTI-PHOSPHATIDYLSERINE/PROTHROMBIN IGG ANTIBODY

LAB5231

Collect

6 mL Gold top tube

Specimen Preparation

Separate cells from serum wihtin 2 hours of collection.

1.0 mL serum

Pediatric Collection

Minimum volume = 0.2 mL serum

Storage/Transport Temperature

Refrigerate and ship to lab at ambient temperature.

Performed by

UCD Rheumatology Laboratory

Performed

Varies

Methodology

ELISA, semi-quantitative

Synonyms

  • LAB5231

Reference Interval

Negatve <30 Units

Positive >30 Units

Performed by

UCD Rheumatology Laboratory

CPT Codes

86849

Collection

LAB5231

Collect

6 mL Gold top tube

Specimen Preparation

Separate cells from serum wihtin 2 hours of collection.

1.0 mL serum

Pediatric Collection

Minimum volume = 0.2 mL serum

Storage/Transport Temperature

Refrigerate and ship to lab at ambient temperature.

Performed by

UCD Rheumatology Laboratory

Ordering

Performed

Varies

Methodology

ELISA, semi-quantitative

Synonyms

  • LAB5231
Result Interpretation

Reference Interval

Negatve <30 Units

Positive >30 Units

Performed by

UCD Rheumatology Laboratory

Administrative

CPT Codes

86849

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