Tests Catalogs

ANTI DNA ANTIBODY

LAB5254

Collect

5.0 mL, gold or red top with gel (SST), (clot activator serum).

Unacceptable Conditions

Excessive hemolysis, chylous serum, gross contamination, inadequate volume of blood, inadequate patient and/or specimen identification.

Storage/Transport Temperature

Internal: Deliver to lab immediately
Offsite: 2 mL Separate serum from cells and deliver to the lab refrigerated.

Stability (from collection to initiation)

Refrigerated: 1-2 weeks; Frozen: Indefinitely.

Remarks

Separate serum and refrigerate, serum must be separated from clot within 2 hours.

Performed by

PCL Clinical Laboratory

Performed

2-3 times per week

Methodology

Enzyme-linked immunosorbent assay (ELISA)

Reported

Same day

Synonyms

  • -247 Anti-dsDNA Antibody
  • LAB3636
  • Double Stranded DNA Antibody
  • DS DNA AB

Reference Interval

0-30 Units

Interpretive Data

REFERENCE RANGES: Normal 0 - 30 Units
Borderline Positive 30 - 50 Units
Moderately Positive 50 - 100 Units
High Positive > 100 Units

 

Moderate to high levels of Anti-dsDNA are considered highly specific for the

diagnosis of SLE and correlate with active disease; notably renal disease.

Performed by

PCL Clinical Laboratory

CPT Codes

86225

Collection

LAB5254

Collect

5.0 mL, gold or red top with gel (SST), (clot activator serum).

Unacceptable Conditions

Excessive hemolysis, chylous serum, gross contamination, inadequate volume of blood, inadequate patient and/or specimen identification.

Storage/Transport Temperature

Internal: Deliver to lab immediately
Offsite: 2 mL Separate serum from cells and deliver to the lab refrigerated.

Stability (from collection to initiation)

Refrigerated: 1-2 weeks; Frozen: Indefinitely.

Remarks

Separate serum and refrigerate, serum must be separated from clot within 2 hours.

Performed by

PCL Clinical Laboratory

Ordering

Performed

2-3 times per week

Methodology

Enzyme-linked immunosorbent assay (ELISA)

Reported

Same day

Synonyms

  • -247 Anti-dsDNA Antibody
  • LAB3636
  • Double Stranded DNA Antibody
  • DS DNA AB
Result Interpretation

Reference Interval

0-30 Units

Interpretive Data

REFERENCE RANGES: Normal 0 - 30 Units
Borderline Positive 30 - 50 Units
Moderately Positive 50 - 100 Units
High Positive > 100 Units

 

Moderate to high levels of Anti-dsDNA are considered highly specific for the

diagnosis of SLE and correlate with active disease; notably renal disease.

Performed by

PCL Clinical Laboratory

Administrative

CPT Codes

86225

ANTI-68 KD (HEAT SHOCK PROTEIN 70) IGG ANTIBODIES BY IMMUNOBLOT

LAB3467

Collect

Serum Separator Tube (SST) or Plain Red.

Specimen Preparation

Transfer 0.5 mL serum to an ARUP Standard Transport Tube. (Min: 0.1 mL)

Unacceptable Conditions

Urine or plasma. Heat inactivated and contaminated specimens.

Storage/Transport Temperature

Ship to lab refrigerated.

Stability (from collection to initiation)

Ambient: 48 hours; Refrigerated: 2 weeks; Frozen: 1 year

Performed

Sun, Tue, Thu

Methodology

Qualitative Immunoblot

Reported

5-18 days

Synonyms

  • 68KD ANTIBODIES BY WESTERN BLOT
  • HEAT SHOCK PROTEIN 70 IGG AB
  • LAB3467
  • ANTI-COCHLEAR AB
  • 68KD HSP

Ordering Recommendations

Not recommended for evaluation of general hearing loss.

Reference Interval

Negative

Interpretive Data

The presence of HSP70 IgG antibodies may be useful in predicting corticosteroid responsiveness in a subset of patients with autoimmune inner ear disease (AIED) characterized by idiopathic rapidly progressive sensorineural hearing loss (SNHL). HSP70 IgG antibodies are also associated with a number of autoimmune diseases and have also been reported in apparently healthy individuals. A negative result does not rule out response to treatment or to a diagnosis of AIED.

CPT Codes

83516
Collection

LAB3467

Collect

Serum Separator Tube (SST) or Plain Red.

Specimen Preparation

Transfer 0.5 mL serum to an ARUP Standard Transport Tube. (Min: 0.1 mL)

Unacceptable Conditions

Urine or plasma. Heat inactivated and contaminated specimens.

Storage/Transport Temperature

Ship to lab refrigerated.

Stability (from collection to initiation)

Ambient: 48 hours; Refrigerated: 2 weeks; Frozen: 1 year
Ordering

Performed

Sun, Tue, Thu

Methodology

Qualitative Immunoblot

Reported

5-18 days

Synonyms

  • 68KD ANTIBODIES BY WESTERN BLOT
  • HEAT SHOCK PROTEIN 70 IGG AB
  • LAB3467
  • ANTI-COCHLEAR AB
  • 68KD HSP

Ordering Recommendations

Not recommended for evaluation of general hearing loss.
Result Interpretation

Reference Interval

Negative

Interpretive Data

The presence of HSP70 IgG antibodies may be useful in predicting corticosteroid responsiveness in a subset of patients with autoimmune inner ear disease (AIED) characterized by idiopathic rapidly progressive sensorineural hearing loss (SNHL). HSP70 IgG antibodies are also associated with a number of autoimmune diseases and have also been reported in apparently healthy individuals. A negative result does not rule out response to treatment or to a diagnosis of AIED.

Administrative

CPT Codes

83516

ANTIBODY IDENTIFICATION

Collect

One 6 mL pink top labeled with patient's last name, first mr# , date drawn, phleb initials, One 5 mL purple top labeled as above.

Unacceptable Conditions

Improperly labeled specimen, wrong specimen container, gross hemolysis, insufficient quantity

Storage/Transport Temperature

Internal: Deliver to lab immediately
Offsite: 3 mL pink top or purple top. Transport at room temperature to the lab.

Stability (from collection to initiation)

8 hours at room temperature, 72 hours if refrigerated

Remarks

Ordered on patients with a positive antibody screen. Test is automatically performed on all positive antibody screens.

Performed by

PCL Clinical Laboratory

Performed

Daily

Methodology

Panel for identification, antigen testing corresponding to antibodies identified, DAT and Rh phenotype if necessary

Reported

Same day

Performed by

PCL Clinical Laboratory
Collection

Collect

One 6 mL pink top labeled with patient's last name, first mr# , date drawn, phleb initials, One 5 mL purple top labeled as above.

Unacceptable Conditions

Improperly labeled specimen, wrong specimen container, gross hemolysis, insufficient quantity

Storage/Transport Temperature

Internal: Deliver to lab immediately
Offsite: 3 mL pink top or purple top. Transport at room temperature to the lab.

Stability (from collection to initiation)

8 hours at room temperature, 72 hours if refrigerated

Remarks

Ordered on patients with a positive antibody screen. Test is automatically performed on all positive antibody screens.

Performed by

PCL Clinical Laboratory
Ordering

Performed

Daily

Methodology

Panel for identification, antigen testing corresponding to antibodies identified, DAT and Rh phenotype if necessary

Reported

Same day
Result Interpretation

Performed by

PCL Clinical Laboratory
Administrative

ANTIBODY SCREEN

Collect

One 6.0 mL Pink top (EDTA) labeled with  patient's last name, first name, medical record number, date drawn, phlebotomist's initials, and second person verifier's initials.

Utilizing READBACK VERIFICATION, the phlebotomist and a second hospital personnel verify that the patient's identifiers on his/her hospital identification bracelet match those on the blood specimen. Both persons must initial the pink top tube and, if used, the pink Transfusion Service request form.

In the outpatient setting, it is permissible for the patient to verify his/her identification.

Tube must be filled to at least 80% capacity.

Pediatric Collection

Minimum volume: 3 mL whole blood

Unacceptable Conditions

Specimen not properly identified/labeled; serum separator tube; gross hemolysis; insufficient sample volume; incorrect container.

Storage/Transport Temperature

Internal: Deliver to lab immediately.
Offsite: Transport to lab on refrigeratd cold packwithin 24 hours. Do not allow specimen to freeze.

Stability (from collection to initiation)

Ambient: 8 hours; Refrigerated: 72 Hours; Frozen: Unacceptable.

Remarks

Additional specimen may be requested if antibody identification is indicated.

Performed by

PCL Clinical Laboratory - Transfusion Service/Blood Bank

Performed

Daily

Methodology

Hemagglutination (HA).

Reported

Same day

Synonyms

  • Indirect Coombs Test

Performed by

PCL Clinical Laboratory - Transfusion Service/Blood Bank

Collection

Collect

One 6.0 mL Pink top (EDTA) labeled with  patient's last name, first name, medical record number, date drawn, phlebotomist's initials, and second person verifier's initials.

Utilizing READBACK VERIFICATION, the phlebotomist and a second hospital personnel verify that the patient's identifiers on his/her hospital identification bracelet match those on the blood specimen. Both persons must initial the pink top tube and, if used, the pink Transfusion Service request form.

In the outpatient setting, it is permissible for the patient to verify his/her identification.

Tube must be filled to at least 80% capacity.

Pediatric Collection

Minimum volume: 3 mL whole blood

Unacceptable Conditions

Specimen not properly identified/labeled; serum separator tube; gross hemolysis; insufficient sample volume; incorrect container.

Storage/Transport Temperature

Internal: Deliver to lab immediately.
Offsite: Transport to lab on refrigeratd cold packwithin 24 hours. Do not allow specimen to freeze.

Stability (from collection to initiation)

Ambient: 8 hours; Refrigerated: 72 Hours; Frozen: Unacceptable.

Remarks

Additional specimen may be requested if antibody identification is indicated.

Performed by

PCL Clinical Laboratory - Transfusion Service/Blood Bank

Ordering

Performed

Daily

Methodology

Hemagglutination (HA).

Reported

Same day

Synonyms

  • Indirect Coombs Test
Result Interpretation

Performed by

PCL Clinical Laboratory - Transfusion Service/Blood Bank

Administrative

ANTI-CARDIOLIPIN IGA ANTIBODY

LAB1734

Collect

One 4.5 mL Red or Gold top tube with gel separator (SST).

Unacceptable Conditions

Excessive hemolysis, chylous serum, gross contamination, inadequate volume of blood, inadequate patient and/or specimen indentification.

Storage/Transport Temperature

Internal: Deliver to lab immediately at room temperature
Offsite: Separate serum from cells within 2 hours of collection. Deliver 2 ml serum to lab refrigerated.

Stability (from collection to initiation)

Refrigerated: 1-2 weeks; Frozen: Indefinitely.

Performed by

PCL Clinical Laboratory

Performed

Once Weekly

Methodology

Enzyme-linked Immunoassay

Reported

In 14 days

Synonyms

  • -791 Anti-Cardiolipin Antibody IgA
  • PHOSPHOLIPID (CARDIOLIPIN) IGA
  • LAB1734

Reference Interval

0-20 Units

Performed by

PCL Clinical Laboratory

CPT Codes

86147

Collection

LAB1734

Collect

One 4.5 mL Red or Gold top tube with gel separator (SST).

Unacceptable Conditions

Excessive hemolysis, chylous serum, gross contamination, inadequate volume of blood, inadequate patient and/or specimen indentification.

Storage/Transport Temperature

Internal: Deliver to lab immediately at room temperature
Offsite: Separate serum from cells within 2 hours of collection. Deliver 2 ml serum to lab refrigerated.

Stability (from collection to initiation)

Refrigerated: 1-2 weeks; Frozen: Indefinitely.

Performed by

PCL Clinical Laboratory

Ordering

Performed

Once Weekly

Methodology

Enzyme-linked Immunoassay

Reported

In 14 days

Synonyms

  • -791 Anti-Cardiolipin Antibody IgA
  • PHOSPHOLIPID (CARDIOLIPIN) IGA
  • LAB1734
Result Interpretation

Reference Interval

0-20 Units

Performed by

PCL Clinical Laboratory

Administrative

CPT Codes

86147

ANTI-CARDIOLIPIN IGG ANTIBODY

LAB1735

Collect

5.0 mL, gold or red top with gel (SST), (clot activator serum).

Unacceptable Conditions

Excessive hemolysis, chylous serum, gross contamination, inadequate volume of blood, inadequate patient and/or specimen identification.

Storage/Transport Temperature

Internal: Deliver to lab immediately
Offsite: 2 mL Separate serum from cells and deliver to the lab refrigerated.

Stability (from collection to initiation)

Refrigerated: 1-2 weeks; Frozen: Indefinitely.

Remarks

Remove serum from clot wthin 2 hours after drawing. Refrigerate specimen.

Performed by

PCL Clinical Laboratory

Performed

Once Weekly

Methodology

Enzyme-linked immunoassay

Reported

In 14 days

Synonyms

  • CARDIGG
  • LAB1735
  • CARDIOLIPIN IGG ANTIBODY

Reference Interval

0-20 Units

Interpretive Data

REFERENCE RANGES: Negative < 20 Units
Moderately Positive 20-80 Units
Strongly Positive > 80 Units
Elevated antibody levels may occur in asymptomatic patients; results should
be interpreted within the clinical context of each patient.

Performed by

PCL Clinical Laboratory

CPT Codes

86147

Collection

LAB1735

Collect

5.0 mL, gold or red top with gel (SST), (clot activator serum).

Unacceptable Conditions

Excessive hemolysis, chylous serum, gross contamination, inadequate volume of blood, inadequate patient and/or specimen identification.

Storage/Transport Temperature

Internal: Deliver to lab immediately
Offsite: 2 mL Separate serum from cells and deliver to the lab refrigerated.

Stability (from collection to initiation)

Refrigerated: 1-2 weeks; Frozen: Indefinitely.

Remarks

Remove serum from clot wthin 2 hours after drawing. Refrigerate specimen.

Performed by

PCL Clinical Laboratory

Ordering

Performed

Once Weekly

Methodology

Enzyme-linked immunoassay

Reported

In 14 days

Synonyms

  • CARDIGG
  • LAB1735
  • CARDIOLIPIN IGG ANTIBODY
Result Interpretation

Reference Interval

0-20 Units

Interpretive Data

REFERENCE RANGES: Negative < 20 Units
Moderately Positive 20-80 Units
Strongly Positive > 80 Units
Elevated antibody levels may occur in asymptomatic patients; results should
be interpreted within the clinical context of each patient.

Performed by

PCL Clinical Laboratory

Administrative

CPT Codes

86147

ANTI-CARDIOLIPIN IGM ANTIBODY

LAB1736

Collect

5.0 mL, gold or red top with gel (SST), (clot activator serum).

Unacceptable Conditions

Excessive hemolysis, chylous serum, gross contamination, inadequate volume of blood, inadequate patient and/or specimen identification.

Storage/Transport Temperature

Internal: Deliver to lab immediately
Offsite: 2 mL Separate serum from cells and deliver to the lab refrigerated.

Stability (from collection to initiation)

Refrigerated: 1-2 weeks; Frozen: Indefinitely.

Remarks

Remove serum from clot within 2 hours after drawing. Refrigerate specimen.

Performed by

PCL Clinical Laboratory

Performed

Once Weekly

Methodology

Enzyme-linked immunoassay.

Reported

In 14 days

Synonyms

  • PHOSPHOLIPID (CARDIOLIPIN) IGM
  • -235 Anti-Cardiolipin Antibody IgM
  • LAB1736
  • CARDIGM

Reference Interval

0-20 Units

Interpretive Data

REFERENCE RANGES: Negative < 20 Units
Moderately Positive 20 - 80 Units
Strongly Positive > 80 Units
Elevated antibody levels may occur in asymptomatic patients; results should
be interpreted within the clinical context of each patient.

Performed by

PCL Clinical Laboratory

CPT Codes

86147

Collection

LAB1736

Collect

5.0 mL, gold or red top with gel (SST), (clot activator serum).

Unacceptable Conditions

Excessive hemolysis, chylous serum, gross contamination, inadequate volume of blood, inadequate patient and/or specimen identification.

Storage/Transport Temperature

Internal: Deliver to lab immediately
Offsite: 2 mL Separate serum from cells and deliver to the lab refrigerated.

Stability (from collection to initiation)

Refrigerated: 1-2 weeks; Frozen: Indefinitely.

Remarks

Remove serum from clot within 2 hours after drawing. Refrigerate specimen.

Performed by

PCL Clinical Laboratory

Ordering

Performed

Once Weekly

Methodology

Enzyme-linked immunoassay.

Reported

In 14 days

Synonyms

  • PHOSPHOLIPID (CARDIOLIPIN) IGM
  • -235 Anti-Cardiolipin Antibody IgM
  • LAB1736
  • CARDIGM
Result Interpretation

Reference Interval

0-20 Units

Interpretive Data

REFERENCE RANGES: Negative < 20 Units
Moderately Positive 20 - 80 Units
Strongly Positive > 80 Units
Elevated antibody levels may occur in asymptomatic patients; results should
be interpreted within the clinical context of each patient.

Performed by

PCL Clinical Laboratory

Administrative

CPT Codes

86147

ANTI-CD20 THERAPY MONITOR

LAB3055

Collect

One 4.0 to 7.0 mL green top tube, no gel (sodium heparin plasma) AND one 4.0 mL purple top (EDTA plasma) drawn at the same time.

Pediatric Collection

One 3 mL green top tube, no gel (sodium heparin plasma) AND one 4 mL purple top tube (EDTA plasma).

Unacceptable Conditions

Specimens older than 24 hours at ambient temperature; frozen or hemolyzed specimens; specimens received in an incorrect container.

Storage/Transport Temperature

Internal: Deliver to lab immediately.
Offsite: Do not centrifuge. Transport immediately to lab at ambient temperature. Copy of CBC with Differential report from sample collected at the same time may be sent in lieu of purple top tube.

Stability (from collection to initiation)

Do not centrifuge.

Purple Top (Absolute Lymph count):    Ambient, 8 hours; Refrigerated, 36 hours, Frozen, Unacceptable

Green top (Flow CD20PAN):                Ambient, 24 hours; Refrigerated/Frozen, Unacceptable 

Remarks

Stat requests have a turn-around time of 24 hours. CD20 Panel requires an Absolute Lymphocyte Count. A Complete Blood Count (CBC) and differential (DIFF) must be ordered and collected at the same time. CPT code 85025 or 85027 and 85007 will be billed as needed.

Performed by

PCL Clinical Laboratory- Flow Cytometry

Performed

Daily

Methodology

Flow Cytometry

Reported

Same day

Synonyms

  • B-CELL DEFICIENCY PANEL
  • RITUXAN THERAPY MONITOR
  • RITUXIMAB THERAPY MONITOR
  • LAB3055
  • CD20PAN

Reference Interval

By Report

Performed by

PCL Clinical Laboratory- Flow Cytometry

CPT Codes

86355, 86356

Collection

LAB3055

Collect

One 4.0 to 7.0 mL green top tube, no gel (sodium heparin plasma) AND one 4.0 mL purple top (EDTA plasma) drawn at the same time.

Pediatric Collection

One 3 mL green top tube, no gel (sodium heparin plasma) AND one 4 mL purple top tube (EDTA plasma).

Unacceptable Conditions

Specimens older than 24 hours at ambient temperature; frozen or hemolyzed specimens; specimens received in an incorrect container.

Storage/Transport Temperature

Internal: Deliver to lab immediately.
Offsite: Do not centrifuge. Transport immediately to lab at ambient temperature. Copy of CBC with Differential report from sample collected at the same time may be sent in lieu of purple top tube.

Stability (from collection to initiation)

Do not centrifuge.

Purple Top (Absolute Lymph count):    Ambient, 8 hours; Refrigerated, 36 hours, Frozen, Unacceptable

Green top (Flow CD20PAN):                Ambient, 24 hours; Refrigerated/Frozen, Unacceptable 

Remarks

Stat requests have a turn-around time of 24 hours. CD20 Panel requires an Absolute Lymphocyte Count. A Complete Blood Count (CBC) and differential (DIFF) must be ordered and collected at the same time. CPT code 85025 or 85027 and 85007 will be billed as needed.

Performed by

PCL Clinical Laboratory- Flow Cytometry

Ordering

Performed

Daily

Methodology

Flow Cytometry

Reported

Same day

Synonyms

  • B-CELL DEFICIENCY PANEL
  • RITUXAN THERAPY MONITOR
  • RITUXIMAB THERAPY MONITOR
  • LAB3055
  • CD20PAN
Result Interpretation

Reference Interval

By Report

Performed by

PCL Clinical Laboratory- Flow Cytometry

Administrative

CPT Codes

86355, 86356

ANTI-CENTROMERE ANTIBODY

LAB4570

Collect

5.0 mL, gold or red top with gel (SST), (clot activator serum).

Unacceptable Conditions

Excessive hemolysis, chylous serum, gross contamination, inadequate volume of blood, inadequate patient and/or specimen identification.

Storage/Transport Temperature

Internal: Deliver to lab immediately
Offsite: 2 mL serum Separate serum from cells and deliver to the lab refrigerated.

Stability (from collection to initiation)

Refrigerated: 2-3 weeks; Frozen: Indefinitely.

Remarks

Serum must be removed from clot within 2 hours after collection. Refrigerate specimen.

Performed by

PCL Clinical Laboratory

Performed

Mon - Fri dayshift

Methodology

Nuclear antigen is provided by human epithelial (Hep-2) cells grown directly on microscopic slides.

Reported

Same day

Synonyms

  • -207 Anti-Centromere Antibody
  • LAB3110
  • ANTICENT
  • Anti-Centromere Antibody
  • LAB4570

Reference Interval

NEGATIVE

Performed by

PCL Clinical Laboratory

CPT Codes

86255

Collection

LAB4570

Collect

5.0 mL, gold or red top with gel (SST), (clot activator serum).

Unacceptable Conditions

Excessive hemolysis, chylous serum, gross contamination, inadequate volume of blood, inadequate patient and/or specimen identification.

Storage/Transport Temperature

Internal: Deliver to lab immediately
Offsite: 2 mL serum Separate serum from cells and deliver to the lab refrigerated.

Stability (from collection to initiation)

Refrigerated: 2-3 weeks; Frozen: Indefinitely.

Remarks

Serum must be removed from clot within 2 hours after collection. Refrigerate specimen.

Performed by

PCL Clinical Laboratory

Ordering

Performed

Mon - Fri dayshift

Methodology

Nuclear antigen is provided by human epithelial (Hep-2) cells grown directly on microscopic slides.

Reported

Same day

Synonyms

  • -207 Anti-Centromere Antibody
  • LAB3110
  • ANTICENT
  • Anti-Centromere Antibody
  • LAB4570
Result Interpretation

Reference Interval

NEGATIVE

Performed by

PCL Clinical Laboratory

Administrative

CPT Codes

86255

ANTI-CYCLIC CITRULLINATED PEPT

LAB851

Collect

5.0 mL, gold or red top with gel (SST), (clot activator serum).

Unacceptable Conditions

Plasma.

Storage/Transport Temperature

Internal: Deliver to lab immediately
Offsite: 0.5 mL serum Separate serum from cells and deliver to the lab refrigerated.

Stability (from collection to initiation)

Refrigerated: 2-3 weeks; Frozen: Indefinitely.

Remarks

Test used for diagnosing Rheumatoid arthritis.

Performed by

PCL Clinical Laboratory

Performed

Once Weekly

Methodology

Enzyme-Linked Immunosorbent Assay

Reported

Same day

Synonyms

  • -792 Anti-Cyclic Citrullinated Peptide Antibody
  • LAB851

Reference Interval

Negative

Performed by

PCL Clinical Laboratory

CPT Codes

86200

Collection

LAB851

Collect

5.0 mL, gold or red top with gel (SST), (clot activator serum).

Unacceptable Conditions

Plasma.

Storage/Transport Temperature

Internal: Deliver to lab immediately
Offsite: 0.5 mL serum Separate serum from cells and deliver to the lab refrigerated.

Stability (from collection to initiation)

Refrigerated: 2-3 weeks; Frozen: Indefinitely.

Remarks

Test used for diagnosing Rheumatoid arthritis.

Performed by

PCL Clinical Laboratory

Ordering

Performed

Once Weekly

Methodology

Enzyme-Linked Immunosorbent Assay

Reported

Same day

Synonyms

  • -792 Anti-Cyclic Citrullinated Peptide Antibody
  • LAB851
Result Interpretation

Reference Interval

Negative

Performed by

PCL Clinical Laboratory

Administrative

CPT Codes

86200

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