Precision Clinical Laboratory

17-Hydroxycorticosteriods, Urine

LAB351

Collect

24-hour urine. Refrigerated during collection. Also acceptable: Random urine. Freeze within 15 minutes of collection, preservative not required. Reported as mg/L, no reference interval provided.

Specimen Preparation

Transfer 12 mL aliquot of urine from a well-mixed 24-hour collection to ARUP Standard Transport Tubes. Also acceptable: Specimens refrigerated with preservatives are acceptable. Sample pH must be 5.0 - 7.0. Mix well, add 1 g boric acid/100 mL urine, adjust pH (with boric acid) to 5.0-7.0 and freeze. Record total volume, collection time, and pH on transport tube and test request form. Random specimens without preservative are acceptable if frozen within 15 minutes of collection.

Unacceptable Conditions

Alkali preservatives (e.g. specimens previously preserved with NaOH).

Storage/Transport Temperature

Frozen.

Stability (from collection to initiation)

Ambient: 4 hours (with preservative); Refrigerated: 1 week (with preservative); Frozen: 1 month

Performed

Wed, Sat

Methodology

Quantitative Colorimetry

Reported

3-7 days

Synonyms

LAB351
HYD CORT
Cortisol Free Urine
Free Urinary Cortisol
Urinary Free Cortisol
17-Ketogenic Steroid
17-Hydroxycorticosteroids

Reference Interval

Components

Reference Interval

17 OH-Corticosteriods, Urine - mg/g CRT

2.0-6.5 mg/g crt

OH-Corticosteriods, Urine - per volume

4.0-14.0 mg/d

Creatinine, 24-Hour Urine

Age	Male	Female
3-8 years	140-700 mg/d	140-700 mg/d
9-12 years	300-1300 mg/d	300-1300 mg/d
13-17 years	500-2300 mg/d	400-1600 mg/d
18-50 years	1000-2500 mg/d	700-1600 mg/d
51-80 years	800-2100 mg/d	500-1400 mg/d
81 years and older	600-2000 mg/d	400-1300 mg/d

CPT Codes

83491

Collection

LAB351

Collect

24-hour urine. Refrigerated during collection. Also acceptable: Random urine. Freeze within 15 minutes of collection, preservative not required. Reported as mg/L, no reference interval provided.

Specimen Preparation

Unacceptable Conditions

Alkali preservatives (e.g. specimens previously preserved with NaOH).

Storage/Transport Temperature

Frozen.

Stability (from collection to initiation)

Ambient: 4 hours (with preservative); Refrigerated: 1 week (with preservative); Frozen: 1 month

Ordering

Performed

Wed, Sat

Methodology

Quantitative Colorimetry

Reported

3-7 days

Synonyms

LAB351
HYD CORT
Cortisol Free Urine
Free Urinary Cortisol
Urinary Free Cortisol
17-Ketogenic Steroid
17-Hydroxycorticosteroids

Result Interpretation

Reference Interval

Components

Reference Interval

17 OH-Corticosteriods, Urine - mg/g CRT

2.0-6.5 mg/g crt

OH-Corticosteriods, Urine - per volume

4.0-14.0 mg/d

Creatinine, 24-Hour Urine

Age	Male	Female
3-8 years	140-700 mg/d	140-700 mg/d
9-12 years	300-1300 mg/d	300-1300 mg/d
13-17 years	500-2300 mg/d	400-1600 mg/d
18-50 years	1000-2500 mg/d	700-1600 mg/d
51-80 years	800-2100 mg/d	500-1400 mg/d
81 years and older	600-2000 mg/d	400-1300 mg/d

Administrative

CPT Codes

83491

17-Hydroxypregnenolone Quant by MS/MS

LAB530

Collect

Serum separator tube. Also acceptable: Plain red, lavender (EDTA), pink (K₂EDTA), or green (sodium or lithium heparin).

Specimen Preparation

Separate serum or plasma from cells ASAP or within 2 hours of collection. Transfer two 0.5 mL serum or plasma specimens to an ARUP Standard Transport Tube and freeze immediately. (Min: 0.25 mL/container)

Unacceptable Conditions

Refrigerated or room temperature specimens.

Storage/Transport Temperature

CRITICAL FROZEN. Separate specimens must be submitted when multiple tests are ordered.

Stability (from collection to initiation)

After separation from cells: Ambient: Unacceptable; Refrigerated: Unacceptable; Frozen: 6 months

Performed

Mon-Fri

Methodology

Quantitative High Performance Liquid Chromatography-Tandem Mass Spectrometry

Reported

1-4 days

Synonyms

LAB530

Reference Interval

Age	Female	Male
Premature (26-28 weeks)	1219-9799 ng/dL	1219-9799 ng/dL
Premature (29-36 weeks)	346-8911 ng/dL	346-8911 ng/dL
Full Term (1-5 months)	229-3104 ng/dL	229-3104 ng/dL
6-12 months	less than or equal to 917ng/dL	less than or equal to 917ng/dL
13-23 months	less than or equal to 592 ng/dL	less than or equal to 592 ng/dL
2-4 years	less than or equal to 280 ng/dL	less than or equal to 249 ng/dL
5-6 years	less than or equal to 350 ng/dL	less than or equal to 319 ng/dL
7-9 years	less than or equal to 212 ng/dL	less than or equal to 187 ng/dL
10-12 years	less than or equal to 398 ng/dL	less than or equal to 392 ng/dL
13-15 years	less than or equal to 407 ng/dL	35-465 ng/dL
16-17 years	less than or equal to 423 ng/dL	32-478 ng/dL
18 years and older	Less than 226 ng/dL	Less than 442 ng/dL
Tanner Stage I	less than or equal to 235 ng/dL	less than or equal to 208 ng/dL
Tanner Stage II	less than or equal to 367 ng/dL	less than or equal to 355 ng/dL
Tanner Stage III	less than or equal to 430 ng/dL	less than or equal to 450 ng/dL
Tanner Stage IV-V	less than or equal to 412 ng/dL	35-478 ng/dL

CPT Codes

84143

Collection

LAB530

Collect

Serum separator tube. Also acceptable: Plain red, lavender (EDTA), pink (K₂EDTA), or green (sodium or lithium heparin).

Specimen Preparation

Unacceptable Conditions

Refrigerated or room temperature specimens.

Storage/Transport Temperature

CRITICAL FROZEN. Separate specimens must be submitted when multiple tests are ordered.

Stability (from collection to initiation)

After separation from cells: Ambient: Unacceptable; Refrigerated: Unacceptable; Frozen: 6 months

Ordering

Performed

Mon-Fri

Methodology

Quantitative High Performance Liquid Chromatography-Tandem Mass Spectrometry

Reported

1-4 days

Synonyms

LAB530

Result Interpretation

Reference Interval

Age	Female	Male
Premature (26-28 weeks)	1219-9799 ng/dL	1219-9799 ng/dL
Premature (29-36 weeks)	346-8911 ng/dL	346-8911 ng/dL
Full Term (1-5 months)	229-3104 ng/dL	229-3104 ng/dL
6-12 months	less than or equal to 917ng/dL	less than or equal to 917ng/dL
13-23 months	less than or equal to 592 ng/dL	less than or equal to 592 ng/dL
2-4 years	less than or equal to 280 ng/dL	less than or equal to 249 ng/dL
5-6 years	less than or equal to 350 ng/dL	less than or equal to 319 ng/dL
7-9 years	less than or equal to 212 ng/dL	less than or equal to 187 ng/dL
10-12 years	less than or equal to 398 ng/dL	less than or equal to 392 ng/dL
13-15 years	less than or equal to 407 ng/dL	35-465 ng/dL
16-17 years	less than or equal to 423 ng/dL	32-478 ng/dL
18 years and older	Less than 226 ng/dL	Less than 442 ng/dL
Tanner Stage I	less than or equal to 235 ng/dL	less than or equal to 208 ng/dL
Tanner Stage II	less than or equal to 367 ng/dL	less than or equal to 355 ng/dL
Tanner Stage III	less than or equal to 430 ng/dL	less than or equal to 450 ng/dL
Tanner Stage IV-V	less than or equal to 412 ng/dL	35-478 ng/dL

Administrative

CPT Codes

84143

17-Hydroxyprogesterone Qnt, HPLC-MS/MS

LAB720

Collect

Serum separator tube. Also acceptable: Plain red, pink (K₂EDTA), plasma separator tube, green (sodium heparin), or green (lithium heparin).

Specimen Preparation

Transfer 1 mL serum or plasma to an ARUP Standard Transport Tube. (Min: 0.3 mL)

Unacceptable Conditions

Grossly hemolyzed specimens.

Storage/Transport Temperature

Refrigerated. Also acceptable: Frozen.

Stability (from collection to initiation)

After separation from cells: Ambient: Unacceptable; Refrigerated: 1 week; Frozen: 6 months

Performed

Sun-Sat

Methodology

Quantitative High Performance Liquid Chromatography-Tandem Mass Spectrometry

Reported

1-4 days

Synonyms

17a-OH
17a
Progesterone
17-OHP
Hydroxyprogesterone

Reference Interval

Effective August 19, 2013

Age	Female	Male
Premature (26-28 weeks)	124-841 ng/dL	124-841 ng/dL
Premature (29-35 weeks)	26-568 ng/dL	26-568 ng/dL
Full term Day 3	7-77 ng/dL	7-77 ng/dL
4 days-30 days	7-106 ng/dL	Less than 200 ng/dL
1 month-2 months	13-106 ng/dL	Less than 200 ng/dL
3 months-5 months	13-106 ng/dL	3-90 ng/dL
6 months-1 year	Less than or equal to 148 ng/dL	Less than or equal to 148 ng/dL
2-3 years	Less than or equal to 256 ng/dL	Less than or equal to 228 ng/dL
4-6 years	Less than or equal to 299 ng/dL	Less than or equal to 208 ng/dL
7-9 years	Less than or equal to 71 ng/dL	Less than or equal to 63 ng/dL
10-12 years	Less than or equal to 129 ng/dL	Less than or equal to 79 ng/dL
13-15 years	9-208 ng/dL	9-140 ng/dL
16-17 years	Less than or equal to 178 ng/dL	24-192 ng/dL
18 years and older	Less than 207 ng/dL	Less than 139 ng/dL
Follicular	15-70 ng/dL	Does Not Apply
Luteal	35-290 ng/dL	Does Not Apply
Tanner Stage I	Less than or equal to 74 ng/dL	Less than or equal to 62 ng/dL
Tanner Stage II	Less than or equal to 164 ng/dL	Less than or equal to 104 ng/dL
Tanner Stage III	13-209 ng/dL	Less than or equal to 151 ng/dL
Tanner Stage IV-V	7-170 ng/dL	20-173 ng/dL

CPT Codes

83498

Collection

LAB720

Collect

Serum separator tube. Also acceptable: Plain red, pink (K₂EDTA), plasma separator tube, green (sodium heparin), or green (lithium heparin).

Specimen Preparation

Transfer 1 mL serum or plasma to an ARUP Standard Transport Tube. (Min: 0.3 mL)

Unacceptable Conditions

Grossly hemolyzed specimens.

Storage/Transport Temperature

Refrigerated. Also acceptable: Frozen.

Stability (from collection to initiation)

After separation from cells: Ambient: Unacceptable; Refrigerated: 1 week; Frozen: 6 months

Ordering

Performed

Sun-Sat

Methodology

Quantitative High Performance Liquid Chromatography-Tandem Mass Spectrometry

Reported

1-4 days

Synonyms

17a-OH
17a
Progesterone
17-OHP
Hydroxyprogesterone

Result Interpretation

Reference Interval

Effective August 19, 2013

Age	Female	Male
Premature (26-28 weeks)	124-841 ng/dL	124-841 ng/dL
Premature (29-35 weeks)	26-568 ng/dL	26-568 ng/dL
Full term Day 3	7-77 ng/dL	7-77 ng/dL
4 days-30 days	7-106 ng/dL	Less than 200 ng/dL
1 month-2 months	13-106 ng/dL	Less than 200 ng/dL
3 months-5 months	13-106 ng/dL	3-90 ng/dL
6 months-1 year	Less than or equal to 148 ng/dL	Less than or equal to 148 ng/dL
2-3 years	Less than or equal to 256 ng/dL	Less than or equal to 228 ng/dL
4-6 years	Less than or equal to 299 ng/dL	Less than or equal to 208 ng/dL
7-9 years	Less than or equal to 71 ng/dL	Less than or equal to 63 ng/dL
10-12 years	Less than or equal to 129 ng/dL	Less than or equal to 79 ng/dL
13-15 years	9-208 ng/dL	9-140 ng/dL
16-17 years	Less than or equal to 178 ng/dL	24-192 ng/dL
18 years and older	Less than 207 ng/dL	Less than 139 ng/dL
Follicular	15-70 ng/dL	Does Not Apply
Luteal	35-290 ng/dL	Does Not Apply
Tanner Stage I	Less than or equal to 74 ng/dL	Less than or equal to 62 ng/dL
Tanner Stage II	Less than or equal to 164 ng/dL	Less than or equal to 104 ng/dL
Tanner Stage III	13-209 ng/dL	Less than or equal to 151 ng/dL
Tanner Stage IV-V	7-170 ng/dL	20-173 ng/dL

Administrative

CPT Codes

83498

17-Ketosteroids, Urine

LAB350

Collect

24-hour urine. Refrigerate during collection.

Specimen Preparation

Transfer two 4 mL aliquots from a well-mixed 24-hour urine collection into 2 ARUP Standard Transport Tubes or 2 ARUP Standard Transport Tubes containing 20 mg Sulfamic Acid (ARUP supply #48098) available online through eSupply using ARUP Connect™ or by contacting ARUP Client Services at (800) 522-2787. (Min: 3 mL/aliquot) Adequate refrigeration is the most important aspect of specimen preservation.

Storage/Transport Temperature

Refrigerated.

Stability (from collection to initiation)

Ambient: 4 hours; Refrigerated: 2 weeks; Frozen: 1 month

Remarks

Record total volume and collection time interval on transport tube and test request form.

Notes

An alternative and more specific test for adrenal androgen function is Dehydroepiandrosterone Sulfate, Serum (ARUP test code 0070040).

A large number of substances may interfere with this test. Decreases may be caused by carbamazepine, cephaloridine, cephalothin, chlormerodrin, digoxin, glucose, metyrapone, promazine, propoxyphene, reserpine, and others. Increases may be caused by acetone, acetophenide, ascorbic acid, chloramphenicol, chlorothiazide, chlorpromazine, cloxacillin, dexamethasone, erythromycin, ethinamate, etryptamine, methicillin, methyprylon, morphine, oleandomycin, oxacillin, penicillin, phenaglycodol, phenazopyridine, phenothiazine, piperidine, quinidine, secobarbital, spironolactone, and others.

Performed

Mon, Wed, Fri

Methodology

Quantitative Spectrophotometry

Reported

1-5 days

Synonyms

17-Ketosteroids, Urine
LAB350
17-KETO

Ordering Recommendations

Assess adrenal androgen production. Preferred test is serum dehydroepiandrosterone sulfate (0070040).

Reference Interval

Components

Reference Interval

17-Ketosteroids - per 24h

Male	Female
0-11 months: 0.0-1.0 mg/d 1-5 years: 1.0-2.0 mg/d 6-10 years: 1.0-4.4 mg/d 11-12 years: 1.3-8.5 mg/d 13-16 years: 3.4-9.8 mg/d 17-50 years: 5.3-17.6 mg/d 51 years and older: 4.1-12.1 mg/d	0-11 months: 0.0-1.0 mg/d 1-5 years: 1.0-2.0 mg/d 6-10 years: 1.4-3.9 mg/d 11-12 years: 3.8-9.5 mg/d 13-16 years: 4.5-17.1 mg/d 17-50 years: 4.4-14.2 mg/d 51 years and older: 3.2-10.6 mg/d

17-Ketosteroids - per volume

Not available

Creatinine, Urine - per 24h

Age	Male	Female
3-8 years	140-700 mg/d	140-700 mg/d
9-12 years	300-1300 mg/d	300-1300 mg/d
13-17 years	500-2300 mg/d	400-1600 mg/d
18-50 years	1000-2500 mg/d	700-1600 mg/d
51-80 years	800-2100 mg/d	500-1400 mg/d
81 years and older	600-2000 mg/d	400-1300 mg/d

Creatinine, Urine - per volume

No reference interval

Interpretive Data

Reference intervals for random urine samples (mg/L) are not available.

CPT Codes

83586

Collection

LAB350

Collect

24-hour urine. Refrigerate during collection.

Specimen Preparation

Storage/Transport Temperature

Refrigerated.

Stability (from collection to initiation)

Ambient: 4 hours; Refrigerated: 2 weeks; Frozen: 1 month

Remarks

Record total volume and collection time interval on transport tube and test request form.

Notes

Ordering

Performed

Mon, Wed, Fri

Methodology

Quantitative Spectrophotometry

Reported

1-5 days

Synonyms

17-Ketosteroids, Urine
LAB350
17-KETO

Ordering Recommendations

Assess adrenal androgen production. Preferred test is serum dehydroepiandrosterone sulfate (0070040).

Result Interpretation

Reference Interval

Components

Reference Interval

17-Ketosteroids - per 24h

Male	Female
0-11 months: 0.0-1.0 mg/d 1-5 years: 1.0-2.0 mg/d 6-10 years: 1.0-4.4 mg/d 11-12 years: 1.3-8.5 mg/d 13-16 years: 3.4-9.8 mg/d 17-50 years: 5.3-17.6 mg/d 51 years and older: 4.1-12.1 mg/d	0-11 months: 0.0-1.0 mg/d 1-5 years: 1.0-2.0 mg/d 6-10 years: 1.4-3.9 mg/d 11-12 years: 3.8-9.5 mg/d 13-16 years: 4.5-17.1 mg/d 17-50 years: 4.4-14.2 mg/d 51 years and older: 3.2-10.6 mg/d

17-Ketosteroids - per volume

Not available

Creatinine, Urine - per 24h

Age	Male	Female
3-8 years	140-700 mg/d	140-700 mg/d
9-12 years	300-1300 mg/d	300-1300 mg/d
13-17 years	500-2300 mg/d	400-1600 mg/d
18-50 years	1000-2500 mg/d	700-1600 mg/d
51-80 years	800-2100 mg/d	500-1400 mg/d
81 years and older	600-2000 mg/d	400-1300 mg/d

Creatinine, Urine - per volume

No reference interval

Interpretive Data

Reference intervals for random urine samples (mg/L) are not available.

Administrative

CPT Codes

83586

2 HOUR PET TEST

LAB3571

2 HR PET

Collect

At least 1.0 mL peritoneal dialysate in a sterile container.

Unacceptable Conditions

Specimen not properly identified; incorrect container; insufficient sample volume.

Storage/Transport Temperature

Internal: Deliver to laboratory immediately at ambient temperature.

Offsite: Transport specimen to laboratory at 2-8 degrees C.

Stability (from collection to initiation)

Ambient: 1 hour; Refrigerated: (free of cells) 1 week; Frozen: (free of cells) 6 months.

Remarks

Specimen is tested for creatinine, glucose and urea nitrogen.

Performed by

PCL Clinical Laboratory - Core Chemistry

Performed

Upon receipt

Methodology

Creatinine: Colorimetry

Glucose: O2 Depletion-Enzymatic

Urea nitrogen: Conductivity

Reported

Same day

Synonyms

LAB3571

Performed by

PCL Clinical Laboratory - Core Chemistry

CPT Codes

82570, 82495, and 84520

Collection

LAB3571

2 HR PET

Collect

At least 1.0 mL peritoneal dialysate in a sterile container.

Unacceptable Conditions

Specimen not properly identified; incorrect container; insufficient sample volume.

Storage/Transport Temperature

Internal: Deliver to laboratory immediately at ambient temperature.

Offsite: Transport specimen to laboratory at 2-8 degrees C.

Stability (from collection to initiation)

Ambient: 1 hour; Refrigerated: (free of cells) 1 week; Frozen: (free of cells) 6 months.

Remarks

Specimen is tested for creatinine, glucose and urea nitrogen.

Performed by

PCL Clinical Laboratory - Core Chemistry

Ordering

Performed

Upon receipt

Methodology

Creatinine: Colorimetry

Glucose: O2 Depletion-Enzymatic

Urea nitrogen: Conductivity

Reported

Same day

Synonyms

LAB3571

Result Interpretation

Performed by

PCL Clinical Laboratory - Core Chemistry

Administrative

CPT Codes

82570, 82495, and 84520

21-Hydroxylase Antibody

LAB3098

Collect

Plain red.

Specimen Preparation

Transfer 1 mL serum to an ARUP Standard Transport Tube. (Min: 0.2 mL)

Unacceptable Conditions

Hemolyzed specimens.

Storage/Transport Temperature

Refrigerated.

Stability (from collection to initiation)

After separation from cells: Ambient: Unacceptable; Refrigerated: 1 week; Frozen: 6 months

Performed

Tue

Methodology

Quantitative Radioimmunoassay

Reported

2-10 days

Synonyms

Adrenal Antibodies
21-Hydroxylase Antibody
LAB3098
21-OH AB
Anti-Adrenal Antibody
Adrenal Antibody
Hydroxylase Antibody
21-OH Ab

Additional Technical Information

Additional Technical Information

Ordering Recommendations

Secondary test to diagnose autoimmune disease after adrenal insufficiency confirmed.

Reference Interval

Less than or equal to 1.0 U/mL

Interpretive Data

The presence of 21-hydroxylase antibodies (greater than 1.0 U/mL) is indicative of primary adrenal insufficiency (Addison's disease). Results should be interpreted in the context of clinical symptoms including functional adrenal testing.

In males with adrenal insufficiency and 21-hydroxylase antibodies within the reference interval (less than 1.0 U/mL), X-Linked Adrenoleukodystrophy (X-ALD) should be excluded by using Very Long-Chain Branched Fatty Acids in plasma (ARUP Test Code 2004250) for screening.

CPT Codes

83519

Collection

LAB3098

Collect

Plain red.

Specimen Preparation

Transfer 1 mL serum to an ARUP Standard Transport Tube. (Min: 0.2 mL)

Unacceptable Conditions

Hemolyzed specimens.

Storage/Transport Temperature

Refrigerated.

Stability (from collection to initiation)

After separation from cells: Ambient: Unacceptable; Refrigerated: 1 week; Frozen: 6 months

Ordering

Performed

Tue

Methodology

Quantitative Radioimmunoassay

Reported

2-10 days

Synonyms

Adrenal Antibodies
21-Hydroxylase Antibody
LAB3098
21-OH AB
Anti-Adrenal Antibody
Adrenal Antibody
Hydroxylase Antibody
21-OH Ab

Additional Technical Information

Additional Technical Information

Ordering Recommendations

Secondary test to diagnose autoimmune disease after adrenal insufficiency confirmed.

Result Interpretation

Reference Interval

Less than or equal to 1.0 U/mL

Interpretive Data

Administrative

CPT Codes

83519

4 HOUR PET TEST - DIALYSIS ONLY

LAB3490

4 HR PET

Collect

At least 1.0 mL of peritoneal dialysate in a sterile container.

Unacceptable Conditions

Specimen not properly identified; incorrect container; insufficient sample volume.

Storage/Transport Temperature

Internal: Deliver to laboratory immediately at ambient temperature.

Offsite: Transport specimen to laboratory at 2-8 degrees C.

Stability (from collection to initiation)

Ambient: 1 hour; Refrigerated: (free of cells) 1 week; Frozen: (free of cells) 6 months.

Remarks

Specimen is tested for creatinine, glucose and urea nitrogen.

Performed by

PCL Clinical Laboratory - Core Chemistry

Performed

Upon receipt

Methodology

Creatinine: Colorimetry

Glucose: O2 Depletion-Enzymatic

Urea nitrogen: Conductivity

Reported

Same day

Synonyms

LAB3490

Performed by

PCL Clinical Laboratory - Core Chemistry

CPT Codes

82570, 82945, and 84520

Collection

LAB3490

4 HR PET

Collect

At least 1.0 mL of peritoneal dialysate in a sterile container.

Unacceptable Conditions

Specimen not properly identified; incorrect container; insufficient sample volume.

Storage/Transport Temperature

Internal: Deliver to laboratory immediately at ambient temperature.

Offsite: Transport specimen to laboratory at 2-8 degrees C.

Stability (from collection to initiation)

Ambient: 1 hour; Refrigerated: (free of cells) 1 week; Frozen: (free of cells) 6 months.

Remarks

Specimen is tested for creatinine, glucose and urea nitrogen.

Performed by

PCL Clinical Laboratory - Core Chemistry

Ordering

Performed

Upon receipt

Methodology

Creatinine: Colorimetry

Glucose: O2 Depletion-Enzymatic

Urea nitrogen: Conductivity

Reported

Same day

Synonyms

LAB3490

Result Interpretation

Performed by

PCL Clinical Laboratory - Core Chemistry

Administrative

CPT Codes

82570, 82945, and 84520

5' Nucleotidase

LAB3131

Collect

Serum separator tube.

Specimen Preparation

Allow specimen to clot completely at room temperature. Separate serum from cells ASAP or within 2 hours of collection. Transfer 1 mL serum to an ARUP Standard Transport Tube. (Min: 0.2 mL) Avoid hemolysis.)

Unacceptable Conditions

Room temperature specimens greater than 4 hours old.

Storage/Transport Temperature

Refrigerated.

Stability (from collection to initiation)

Ambient: 4 hours; Refrigerated: 1 week; Frozen: 2 weeks (avoid repeated freeze/thaw cycles)

Performed

Sun-Sat

Methodology

Quantitative Enzymatic

Reported

1-2 days

Synonyms

5'Nucleotidase
LAB3131
5'NUCL
Nucleotidase

Ordering Recommendations

Determine whether enzyme elevation is due to hepatocellular or cholestatic pattern.

Reference Interval

0-15 U/L

CPT Codes

83915

Collection

LAB3131

Collect

Serum separator tube.

Specimen Preparation

Unacceptable Conditions

Room temperature specimens greater than 4 hours old.

Storage/Transport Temperature

Refrigerated.

Stability (from collection to initiation)

Ambient: 4 hours; Refrigerated: 1 week; Frozen: 2 weeks (avoid repeated freeze/thaw cycles)

Ordering

Performed

Sun-Sat

Methodology

Quantitative Enzymatic

Reported

1-2 days

Synonyms

5'Nucleotidase
LAB3131
5'NUCL
Nucleotidase

Ordering Recommendations

Determine whether enzyme elevation is due to hepatocellular or cholestatic pattern.

Result Interpretation

Reference Interval

0-15 U/L

Administrative

CPT Codes

83915

5-A-DIHYDROTESTOSTERONE BY TMS

LAB977

Collect

Plain Red or Serum Separator Tube (SST).

Specimen Preparation

Separate serum from cells ASAP or within 2 hours of collection. Transfer 1 mL serum to an ARUP Standard Transport Tube and freeze immediately. (Min: 0.6 mL)

Unacceptable Conditions

Hemolyzed or lipemic specimens.

Storage/Transport Temperature

Frozen.

Stability (from collection to initiation)

After separation from cells: Ambient: 48 hours; Refrigerated: 5 days; Frozen: 6 months

Performed

Tue-Sun

Methodology

Quantitative High Performance Liquid Chromatography-Tandem Mass Spectrometry

Reported

1-4 days

Synonyms

5ADIHYDROT
DIHYDROTESTOSTERONE
DHT

Reference Interval

Males	Females
Premature: 100.0-530.0 pg/mL Full Term: 50.0-600.0 pg/mL 1 week-6 months: 120.0-850.0 pg/mL 7 months-9 years: 0.0-49.9 pg/mL 10-19 years: 0.0-533.0 pg/mL 20 years and older: 106.0-719.0 pg/mL Tanner Stage I: 1.0-47.6 pg/mL Tanner Stage II: 3.5-397.9 pg/mL Tanner Stage III: 14.8-574.6 pg/mL Tanner Stage IV & V: 44.9-511.8 pg/mL	Premature: 20.0-130.0 pg/mL Full Term: 20.0-150.0 pg/mL 1 week-9 years: 0.0-49.9 pg/mL 10-19 years: 50.0-170.0 pg/mL 20 years and older: 24.0-208.0 pg/mL Tanner Stage I: 1.0-64.3 pg/mL Tanner Stage II: 5.5-95.9 pg/mL Tanner Stage III: 11.4-158.3 pg/mL Tanner Stage IV & V: 18.7-193.8 pg/mL

CPT Codes

82542

Collection

LAB977

Collect

Plain Red or Serum Separator Tube (SST).

Specimen Preparation

Separate serum from cells ASAP or within 2 hours of collection. Transfer 1 mL serum to an ARUP Standard Transport Tube and freeze immediately. (Min: 0.6 mL)

Unacceptable Conditions

Hemolyzed or lipemic specimens.

Storage/Transport Temperature

Frozen.

Stability (from collection to initiation)

After separation from cells: Ambient: 48 hours; Refrigerated: 5 days; Frozen: 6 months

Ordering

Performed

Tue-Sun

Methodology

Quantitative High Performance Liquid Chromatography-Tandem Mass Spectrometry

Reported

1-4 days

Synonyms

5ADIHYDROT
DIHYDROTESTOSTERONE
DHT

Result Interpretation

Reference Interval

Males	Females
Premature: 100.0-530.0 pg/mL Full Term: 50.0-600.0 pg/mL 1 week-6 months: 120.0-850.0 pg/mL 7 months-9 years: 0.0-49.9 pg/mL 10-19 years: 0.0-533.0 pg/mL 20 years and older: 106.0-719.0 pg/mL Tanner Stage I: 1.0-47.6 pg/mL Tanner Stage II: 3.5-397.9 pg/mL Tanner Stage III: 14.8-574.6 pg/mL Tanner Stage IV & V: 44.9-511.8 pg/mL	Premature: 20.0-130.0 pg/mL Full Term: 20.0-150.0 pg/mL 1 week-9 years: 0.0-49.9 pg/mL 10-19 years: 50.0-170.0 pg/mL 20 years and older: 24.0-208.0 pg/mL Tanner Stage I: 1.0-64.3 pg/mL Tanner Stage II: 5.5-95.9 pg/mL Tanner Stage III: 11.4-158.3 pg/mL Tanner Stage IV & V: 18.7-193.8 pg/mL

Administrative

CPT Codes

82542

5-FLUOROCYTOSINE

LAB3040

Collect

Plain red.

Specimen Preparation

Aseptically remove 2 mL serum to a sterile tube (ARUP supply #43115) and freeze. Available online through eSupply using ARUP Connect™ or contact ARUP Client Services at (800) 522-2787. (Min: 1 mL).

Unacceptable Conditions

Plasma.

Storage/Transport Temperature

Frozen.

Stability (from collection to initiation)

Ambient: 2 hours; Refrigerated: 24 hours; Frozen: 1 week

Remarks

Required information includes: time and date of collection, time of last dose, and list of all antibiotics that the patient is receiving or has received in the past 48 hours.

Notes

Please include time of last dose, and list of all antibiotics that the patient is receiving or has received in the past 48 hours. This information is important for laboratory handling and essential for subsequent physician interpretation of results.

Performed

Sun-Sat

Methodology

Quantitative Bioassay

Reported

1-2 days

Synonyms

FLUOROCYTOSINE
FLUCYTOSINE
5-FLUCYTOSINE
LAB3040
5-FC

Ordering Recommendations

Monitor levels of antifungal drug, 5-fluorocytosine.

Interpretive Data

Normal peak serum concentration for 5-fluorocytosine is 30-45 µg/mL with a 2 g PO dose or 60-80 µg/mL with a 100 mg/kg/day PO dose. Trough serum concentration is not well established. Toxicity may be seen with sustained levels greater than 100 µg/mL.

For bioassay measurements, the presence of other antimicrobial agents may interfere with the assay. Other factors that may influence antimicrobial levels include inherent differences among patients and their underlying physical conditions as well as the dose and route of administration of the antimicrobial agent.

CPT Codes

80299

Collection

LAB3040

Collect

Plain red.

Specimen Preparation

Aseptically remove 2 mL serum to a sterile tube (ARUP supply #43115) and freeze. Available online through eSupply using ARUP Connect™ or contact ARUP Client Services at (800) 522-2787. (Min: 1 mL).

Unacceptable Conditions

Plasma.

Storage/Transport Temperature

Frozen.

Stability (from collection to initiation)

Ambient: 2 hours; Refrigerated: 24 hours; Frozen: 1 week

Remarks

Required information includes: time and date of collection, time of last dose, and list of all antibiotics that the patient is receiving or has received in the past 48 hours.

Notes

Ordering

Performed

Sun-Sat

Methodology

Quantitative Bioassay

Reported

1-2 days

Synonyms

FLUOROCYTOSINE
FLUCYTOSINE
5-FLUCYTOSINE
LAB3040
5-FC

Ordering Recommendations

Monitor levels of antifungal drug, 5-fluorocytosine.

Result Interpretation

Interpretive Data

Administrative

CPT Codes

80299

Tests Catalogs

Collect

Specimen Preparation

Unacceptable Conditions

Storage/Transport Temperature

Stability (from collection to initiation)

Performed

Methodology

Reported

Synonyms

Reference Interval

CPT Codes

Collect

Specimen Preparation

Unacceptable Conditions

Storage/Transport Temperature

Stability (from collection to initiation)

Performed

Methodology

Reported

Synonyms

Reference Interval

CPT Codes

Collect

Specimen Preparation

Unacceptable Conditions

Storage/Transport Temperature

Stability (from collection to initiation)

Performed

Methodology

Reported

Synonyms

Reference Interval

CPT Codes

Collect

Specimen Preparation

Unacceptable Conditions

Storage/Transport Temperature

Stability (from collection to initiation)

Performed

Methodology

Reported

Synonyms

Reference Interval

CPT Codes

Collect

Specimen Preparation

Unacceptable Conditions

Storage/Transport Temperature

Stability (from collection to initiation)

Performed

Methodology

Reported

Synonyms

Reference Interval

CPT Codes

Collect

Specimen Preparation

Unacceptable Conditions

Storage/Transport Temperature

Stability (from collection to initiation)

Performed

Methodology

Reported

Synonyms

Reference Interval

CPT Codes

Collect

Specimen Preparation

Storage/Transport Temperature

Stability (from collection to initiation)

Remarks

Notes

Performed

Methodology

Reported

Synonyms

Ordering Recommendations

Reference Interval

Interpretive Data