LAB24
VALPROIC
Collect
One 4.5 mL Green top tube with gel separator (PST).
Pediatric Collection
1.5 mL whole blood or 20 full capillary tubes.
Unacceptable Conditions
Sample not properly identified; incorrect container; insufficient sample volume.
Storage/Transport Temperature
Internal: Deliver to lab immediately
Offsite: Centrifuge within 30 minutes of collection. Send at 2-8 degrees C if tested within 24 hours. Place plasma in aliquot container and send frozen if not tested within 24 hours.
Stability (from collection to initiation)
Refrigerated: 24 hours; Frozen (-20 degrees C): greater than 24 hours
Remarks
Draw trough level just prior to the next dose. If toxicity is suspected draw at any time.
Performed by
PCL Clinical Laboratory - Core
Performed
Daily
Methodology
Immuno-Turbidimetry
Reported
Same day
Synonyms
- Depakene
- Depakote Level
- LAB24
Reference Interval
50.0-100.0 ug/mL
Interpretive Data
Effective 05/20/2014:
In most patients, valproic acid concentrations of 50–100 μg/mL control generalized and partial seizures. Seizure control may improve at levels greater than 100 μg/mL, but toxicity may occur at levels of 100–150 μg/mL. For effective treatment, some patients may require levels outside this range. Therefore, the expected range is provided only as a general guide, and individual patient results should be interpreted in light of clinical signs and symptoms.
Performed by
PCL Clinical Laboratory - Core
CPT Codes
80164
Collection |
LAB24
VALPROIC
Collect
One 4.5 mL Green top tube with gel separator (PST).
Pediatric Collection
1.5 mL whole blood or 20 full capillary tubes.
Unacceptable Conditions
Sample not properly identified; incorrect container; insufficient sample volume.
Storage/Transport Temperature
Internal: Deliver to lab immediately
Offsite: Centrifuge within 30 minutes of collection. Send at 2-8 degrees C if tested within 24 hours. Place plasma in aliquot container and send frozen if not tested within 24 hours.
Stability (from collection to initiation)
Refrigerated: 24 hours; Frozen (-20 degrees C): greater than 24 hours
Remarks
Draw trough level just prior to the next dose. If toxicity is suspected draw at any time.
Performed by
PCL Clinical Laboratory - Core
Ordering |
Performed
Daily
Methodology
Immuno-Turbidimetry
Reported
Same day
Synonyms
- Depakene
- Depakote Level
- LAB24
Result Interpretation |
Reference Interval
50.0-100.0 ug/mL
Interpretive Data
Effective 05/20/2014:
In most patients, valproic acid concentrations of 50–100 μg/mL control generalized and partial seizures. Seizure control may improve at levels greater than 100 μg/mL, but toxicity may occur at levels of 100–150 μg/mL. For effective treatment, some patients may require levels outside this range. Therefore, the expected range is provided only as a general guide, and individual patient results should be interpreted in light of clinical signs and symptoms.
Performed by
PCL Clinical Laboratory - Core
Administrative |
CPT Codes
80164