LAB1134
Collect
Green (sodium or lithium heparin) or Lavender (EDTA).
Specimen Preparation
Transport 2 unfixed, air-dried, and unstained smears to accompany the collected blood (smears should be made from the blood submitted) (Min: 2 smears). AND 5 mL whole blood (Min: 1 mL). Specimens should be refrigerated within 30 minutes after collection..
Unacceptable Conditions
Grossly hemolyzed specimens.
Storage/Transport Temperature
Refrigerated.
Stability (from collection to initiation)
Ambient: Unacceptable; Refrigerated: 72 hours; Frozen: Unacceptable
Performed
Mon-Fri
Methodology
Spectrophotometry
Reported
1-5 days
Synonyms
- LAB1134
- OSMO FRAG
Additional Technical Information
- Time Sensitive
Ordering Recommendations
Functional testing of red blood cell sensitivity to osmotic stress; do not use to distinguish between spherocytes in hereditary spherocytosis and acquired autoimmune hemolytic anemia.
Reference Interval
Within normal curve limits. A graph will accompany laboratory report.
Interpretive Data
For patients with acute hemolysis, a normal red cell osmotic fragility test result cannot exclude an osmotic fragility abnormality since the osmotically labile cells may be hemolyzed and not present. Recommend testing during a state of prolonged homeostasis with stable hematocrit.
CPT Codes
85555
Collection |
LAB1134
Collect
Green (sodium or lithium heparin) or Lavender (EDTA).
Specimen Preparation
Transport 2 unfixed, air-dried, and unstained smears to accompany the collected blood (smears should be made from the blood submitted) (Min: 2 smears). AND 5 mL whole blood (Min: 1 mL). Specimens should be refrigerated within 30 minutes after collection..
Unacceptable Conditions
Grossly hemolyzed specimens.
Storage/Transport Temperature
Refrigerated.
Stability (from collection to initiation)
Ambient: Unacceptable; Refrigerated: 72 hours; Frozen: Unacceptable
Ordering |
Performed
Mon-Fri
Methodology
Spectrophotometry
Reported
1-5 days
Synonyms
- LAB1134
- OSMO FRAG
Additional Technical Information
- Time Sensitive
Ordering Recommendations
Functional testing of red blood cell sensitivity to osmotic stress; do not use to distinguish between spherocytes in hereditary spherocytosis and acquired autoimmune hemolytic anemia.
Result Interpretation |
Reference Interval
Within normal curve limits. A graph will accompany laboratory report.
Interpretive Data
For patients with acute hemolysis, a normal red cell osmotic fragility test result cannot exclude an osmotic fragility abnormality since the osmotically labile cells may be hemolyzed and not present. Recommend testing during a state of prolonged homeostasis with stable hematocrit.
Administrative |
CPT Codes
85555