N-ACETYLASPARTIC ACID S/P

Collect

2 mL green top tube 2 mL red top tube with or without gel

Pediatric Collection

0.3 mL

Storage/Transport Temperature

Internal: Deliver to lab immediately at room temperature
Offsite: 0.5 mL plasma/serum. Ship heparinized plasma/serum frozen.

Performed by

UCD Biochemical Genetics Laboratory

Performed

Weekly (Dayshift), day varies

Reported

7 - 10 days

Performed by

UCD Biochemical Genetics Laboratory

CPT Codes

82543
Collection

Collect

2 mL green top tube 2 mL red top tube with or without gel

Pediatric Collection

0.3 mL

Storage/Transport Temperature

Internal: Deliver to lab immediately at room temperature
Offsite: 0.5 mL plasma/serum. Ship heparinized plasma/serum frozen.

Performed by

UCD Biochemical Genetics Laboratory
Ordering

Performed

Weekly (Dayshift), day varies

Reported

7 - 10 days
Result Interpretation

Performed by

UCD Biochemical Genetics Laboratory
Administrative

CPT Codes

82543

N-ACETYLASPARTIC ACID UR

Collect

2 mL green top tube 2 mL red top tube with or without gel

Pediatric Collection

0.3 mL

Storage/Transport Temperature

Internal: Deliver to lab immediately at room temperature
Offsite: 0.5 mL plasma/serum. Ship heparinized plasma/serum frozen.

Performed by

UCD Biochemical Genetics Laboratory

Performed

Weekly (Dayshift), day varies

Reported

7 - 10 days

Performed by

UCD Biochemical Genetics Laboratory

CPT Codes

82543
Collection

Collect

2 mL green top tube 2 mL red top tube with or without gel

Pediatric Collection

0.3 mL

Storage/Transport Temperature

Internal: Deliver to lab immediately at room temperature
Offsite: 0.5 mL plasma/serum. Ship heparinized plasma/serum frozen.

Performed by

UCD Biochemical Genetics Laboratory
Ordering

Performed

Weekly (Dayshift), day varies

Reported

7 - 10 days
Result Interpretation

Performed by

UCD Biochemical Genetics Laboratory
Administrative

CPT Codes

82543

NEISERRIA GONORRHOEAE CULTURE

LAB3353

 

Collect

Collect the following specimens using an ESwab. Source of specimen is required. Throat, Rectal, Prostatic Fluid, Urethra (female), Conjuctiva.

Other fluids: Order C MISC and indicate "R/O GC". Submit in sterile container.

Unacceptable Conditions

Specimen not properly identified; incorrect container; insufficient sample volume; non-ESwab specimen is greater than 1 hour old;nonsterile or leaking containers; refrigerated or frozen specimens.

Storage/Transport Temperature

Internal: Deliver non-ESwab samples to lab immediately within 1 hour. Deliver ESwab samples to lab same day.
Offsite: Deliver non-ESwab samples to lab immediately within 1 hour. Deliver ESwab samples to lab same day.

Stability (from collection to initiation)

ESwab: Ambient, 24 hours. All other containers: Ambient, 1 hour.

All containers: Refrigerated, Unacceptable; Frozen, Unacceptable

Remarks

Female endocervical  swabs, male urethral swabs or first catch urines should be performed by PCR methods.

 

 

Performed by

PCL Clinical Laboratory - Microbiology

Performed

Setup: Daily

Methodology

Standard reference procedures for N. gonorrhoeae culture and identification

Reported

Preliminary: 1 day
Final: negative at 2 days
Positive: as soon as detected

Synonyms

  • GONORRHEA CULTURE
  • GC CULTURE
  • LAB3353

Reference Interval

Culture negative for Neisseria gonorrhoeae. 

Performed by

PCL Clinical Laboratory - Microbiology

CPT Codes

87081 Presumptive identification; If definitive identification is required add 87077

Collection

LAB3353

 

Collect

Collect the following specimens using an ESwab. Source of specimen is required. Throat, Rectal, Prostatic Fluid, Urethra (female), Conjuctiva.

Other fluids: Order C MISC and indicate "R/O GC". Submit in sterile container.

Unacceptable Conditions

Specimen not properly identified; incorrect container; insufficient sample volume; non-ESwab specimen is greater than 1 hour old;nonsterile or leaking containers; refrigerated or frozen specimens.

Storage/Transport Temperature

Internal: Deliver non-ESwab samples to lab immediately within 1 hour. Deliver ESwab samples to lab same day.
Offsite: Deliver non-ESwab samples to lab immediately within 1 hour. Deliver ESwab samples to lab same day.

Stability (from collection to initiation)

ESwab: Ambient, 24 hours. All other containers: Ambient, 1 hour.

All containers: Refrigerated, Unacceptable; Frozen, Unacceptable

Remarks

Female endocervical  swabs, male urethral swabs or first catch urines should be performed by PCR methods.

 

 

Performed by

PCL Clinical Laboratory - Microbiology

Ordering

Performed

Setup: Daily

Methodology

Standard reference procedures for N. gonorrhoeae culture and identification

Reported

Preliminary: 1 day
Final: negative at 2 days
Positive: as soon as detected

Synonyms

  • GONORRHEA CULTURE
  • GC CULTURE
  • LAB3353
Result Interpretation

Reference Interval

Culture negative for Neisseria gonorrhoeae. 

Performed by

PCL Clinical Laboratory - Microbiology

Administrative

CPT Codes

87081 Presumptive identification; If definitive identification is required add 87077

NEUROMYELITIS OPTICA (NMO)/AQUAPORIN-4 IGG

LAB3097

 

Collect

Serum Separator Tube.

Specimen Preparation

Separate from cells ASAP or within 2 hours of collection. Transfer 1 mL serum to an ARUP Standard Transport Tube. (Min: 0.3 mL)

Unacceptable Conditions

Amniotic fluid, ocular fluid peritoneal fluid, synovial fluid, or plasma. Contaminated, hemolyzed, icteric, or lipemic specimens.

Storage/Transport Temperature

Refrigerated.

Stability (from collection to initiation)

After separation from cells: Ambient: 72 hours; Refrigerated: 2 weeks; Frozen: 1 month (avoid repeated freeze/thaw cycles)

Performed

Tue, Thu

Methodology

Semi-Quantitative Enzyme-Linked Immunosorbent Assay

Reported

1-6 days

Synonyms

  • AQUAPORIN IGG AB
  • AQP4 IGG AB
  • DEVIC'S ANTIBODY
  • NMO IGG AB
  • LAB3097
  • AQP4
  • NEUROMYEL

Additional Technical Information

Ordering Recommendations

Aids in evaluation of neuromyelitis optica (NMO) and NMO spectrum disorders.

Reference Interval

Effective October 3, 2016
Negative2.9 U/mL or less
Positive3.0 U/mL or greater

Interpretive Data

Approximately 75 percent of patients with neuromyelitis optica (NMO) express antibodies to the aquaporin-4 (AQP4) receptor.  Diagnosis of NMO requires the presence of longitudinally extensive acute myelitis (lesions extending over 3 or more vertebral segments) and optic neuritis.  While absence of antibodies to the AQP4 receptor does not rule out the diagnosis of NMO, presence of this antibody is diagnostic for NMO.

CPT Codes

83516
Collection

LAB3097

 

Collect

Serum Separator Tube.

Specimen Preparation

Separate from cells ASAP or within 2 hours of collection. Transfer 1 mL serum to an ARUP Standard Transport Tube. (Min: 0.3 mL)

Unacceptable Conditions

Amniotic fluid, ocular fluid peritoneal fluid, synovial fluid, or plasma. Contaminated, hemolyzed, icteric, or lipemic specimens.

Storage/Transport Temperature

Refrigerated.

Stability (from collection to initiation)

After separation from cells: Ambient: 72 hours; Refrigerated: 2 weeks; Frozen: 1 month (avoid repeated freeze/thaw cycles)
Ordering

Performed

Tue, Thu

Methodology

Semi-Quantitative Enzyme-Linked Immunosorbent Assay

Reported

1-6 days

Synonyms

  • AQUAPORIN IGG AB
  • AQP4 IGG AB
  • DEVIC'S ANTIBODY
  • NMO IGG AB
  • LAB3097
  • AQP4
  • NEUROMYEL

Additional Technical Information

Ordering Recommendations

Aids in evaluation of neuromyelitis optica (NMO) and NMO spectrum disorders.
Result Interpretation

Reference Interval

Effective October 3, 2016
Negative2.9 U/mL or less
Positive3.0 U/mL or greater

Interpretive Data

Approximately 75 percent of patients with neuromyelitis optica (NMO) express antibodies to the aquaporin-4 (AQP4) receptor.  Diagnosis of NMO requires the presence of longitudinally extensive acute myelitis (lesions extending over 3 or more vertebral segments) and optic neuritis.  While absence of antibodies to the AQP4 receptor does not rule out the diagnosis of NMO, presence of this antibody is diagnostic for NMO.

Administrative

CPT Codes

83516

NEUROMYELITIS OPTICA ANTIBODY - CSF

LAB3656

 

Collect

CSF.

Specimen Preparation

Transfer 0.5 mL CSF to an ARUP Standard Transport Tube. (Min: 0.15 mL)

Unacceptable Conditions

Hemolyzed, contaminated specimens or severely lipemic specimens.

Storage/Transport Temperature

Refrigerated.

Stability (from collection to initiation)

Ambient: 48 hours; Refrigerated: 2 weeks; Frozen: 1 year

Notes

If AQP4 antibody IgG is positive, then an AQP4 antibody IgG titer is reported. Additional charges apply.

Performed

Wed

Methodology

Semi-Quantitative Indirect Fluorescent Antibody

Reported

1-8 days

Synonyms

  • LAB3656
  • AQP4 CSF
  • NMOAB CSF

Additional Technical Information

Ordering Recommendations

Use in conjunction with serum autoantibody tests to diagnose neuromyelitis optica (NMO).

Reference Interval

less than 1:1

Interpretive Data

Diagnosis of neuromyelitis optica (NMO) requires the presence of longitudinally extensive acute myelitis (lesions extending over 3 or more vertebral segments) and optic neuritis. Approximately 75 percent of patients with NMO express antibodies to the aquaporin-4 (AQP4) receptor. While the absence of AQP4 receptor antibodies does not rule out a diagnosis of NMO, presence of this antibody is diagnostic for NMO.

CPT Codes

86255; if reflexed, add 86256
Collection

LAB3656

 

Collect

CSF.

Specimen Preparation

Transfer 0.5 mL CSF to an ARUP Standard Transport Tube. (Min: 0.15 mL)

Unacceptable Conditions

Hemolyzed, contaminated specimens or severely lipemic specimens.

Storage/Transport Temperature

Refrigerated.

Stability (from collection to initiation)

Ambient: 48 hours; Refrigerated: 2 weeks; Frozen: 1 year

Notes

If AQP4 antibody IgG is positive, then an AQP4 antibody IgG titer is reported. Additional charges apply.
Ordering

Performed

Wed

Methodology

Semi-Quantitative Indirect Fluorescent Antibody

Reported

1-8 days

Synonyms

  • LAB3656
  • AQP4 CSF
  • NMOAB CSF

Additional Technical Information

Ordering Recommendations

Use in conjunction with serum autoantibody tests to diagnose neuromyelitis optica (NMO).
Result Interpretation

Reference Interval

less than 1:1

Interpretive Data

Diagnosis of neuromyelitis optica (NMO) requires the presence of longitudinally extensive acute myelitis (lesions extending over 3 or more vertebral segments) and optic neuritis. Approximately 75 percent of patients with NMO express antibodies to the aquaporin-4 (AQP4) receptor. While the absence of AQP4 receptor antibodies does not rule out a diagnosis of NMO, presence of this antibody is diagnostic for NMO.

Administrative

CPT Codes

86255; if reflexed, add 86256

NEURONAL CELL AB - CSF

LAB3334

 

Collect

CSF.

Specimen Preparation

Transfer 2 mL CSF to an ARUP Standard Transport Tube. (Min: 1 mL)

Storage/Transport Temperature

Frozen.

Stability (from collection to initiation)

Ambient: Unacceptable; Refrigerated: 2 weeks; Frozen: Indefinitely

Performed

Varies

Methodology

Enzyme-Linked Immunosorbent Assay

Reported

5-8 days

Synonyms

  • LAB3334
  • NEURONAL CSF
  • NEURONABC

Reference Interval

By report

CPT Codes

83520
Collection

LAB3334

 

Collect

CSF.

Specimen Preparation

Transfer 2 mL CSF to an ARUP Standard Transport Tube. (Min: 1 mL)

Storage/Transport Temperature

Frozen.

Stability (from collection to initiation)

Ambient: Unacceptable; Refrigerated: 2 weeks; Frozen: Indefinitely
Ordering

Performed

Varies

Methodology

Enzyme-Linked Immunosorbent Assay

Reported

5-8 days

Synonyms

  • LAB3334
  • NEURONAL CSF
  • NEURONABC
Result Interpretation

Reference Interval

By report
Administrative

CPT Codes

83520

NEURONAL CELL ANTIBODIES

LAB3086

 

Collect

Plain red or serum separator tube (SST).

Specimen Preparation

Transfer 1 mL serum to an ARUP Standard Transport Tube. (Min: 0.5 mL)

Storage/Transport Temperature

Frozen.

Stability (from collection to initiation)

Ambient: Unacceptable; Refrigerated: 2 weeks; Frozen: Indefinitely

Performed

Varies

Methodology

Quantitative Enzyme Immunoassay

Reported

3-4 days

Synonyms

  • Anti-Neuronal Cell Antibodies, Serum
  • LAB3086
  • NEURONAL S
  • NEURONAB

Reference Interval

By report

CPT Codes

83520
Collection

LAB3086

 

Collect

Plain red or serum separator tube (SST).

Specimen Preparation

Transfer 1 mL serum to an ARUP Standard Transport Tube. (Min: 0.5 mL)

Storage/Transport Temperature

Frozen.

Stability (from collection to initiation)

Ambient: Unacceptable; Refrigerated: 2 weeks; Frozen: Indefinitely
Ordering

Performed

Varies

Methodology

Quantitative Enzyme Immunoassay

Reported

3-4 days

Synonyms

  • Anti-Neuronal Cell Antibodies, Serum
  • LAB3086
  • NEURONAL S
  • NEURONAB
Result Interpretation

Reference Interval

By report
Administrative

CPT Codes

83520

NEURON-SPECIFIC ENOLASE/NSE

LAB3087

 

Collect

Plain red.

Specimen Preparation

Allow specimen to clot completely at room temperature. Separate serum from cells immediately to avoid release of NSE from blood cells. Transfer 1 mL serum to an ARUP Standard Transport Tube. (Min: 0.5 mL)

Unacceptable Conditions

Plasma. Hemolyzed specimens.

Storage/Transport Temperature

Frozen.

Stability (from collection to initiation)

Ambient: Unacceptable; Refrigerated: 24 hours; Frozen: 1 year (avoid repeated freeze/thaw cycles)

Performed

Mon, Wed, Fri

Methodology

Quantitative Enzyme-Linked Immunosorbent Assay

Reported

1-4 days

Synonyms

  • NSE
  • LAB3087
  • NEURON

Ordering Recommendations

Use as a tumor marker for evaluation of neuroendocrine tumors.

Reference Interval

3.7-8.9 µg/L

Interpretive Data

This assay is performed using the CanAg®  Neuron Specific Enolase Enzyme Immunoassay. Results obtained with different assay methods or kits cannot be used interchangeably.

CPT Codes

86316
Collection

LAB3087

 

Collect

Plain red.

Specimen Preparation

Allow specimen to clot completely at room temperature. Separate serum from cells immediately to avoid release of NSE from blood cells. Transfer 1 mL serum to an ARUP Standard Transport Tube. (Min: 0.5 mL)

Unacceptable Conditions

Plasma. Hemolyzed specimens.

Storage/Transport Temperature

Frozen.

Stability (from collection to initiation)

Ambient: Unacceptable; Refrigerated: 24 hours; Frozen: 1 year (avoid repeated freeze/thaw cycles)
Ordering

Performed

Mon, Wed, Fri

Methodology

Quantitative Enzyme-Linked Immunosorbent Assay

Reported

1-4 days

Synonyms

  • NSE
  • LAB3087
  • NEURON

Ordering Recommendations

Use as a tumor marker for evaluation of neuroendocrine tumors.
Result Interpretation

Reference Interval

3.7-8.9 µg/L

Interpretive Data

This assay is performed using the CanAg®  Neuron Specific Enolase Enzyme Immunoassay. Results obtained with different assay methods or kits cannot be used interchangeably.

Administrative

CPT Codes

86316

NEUTRALIZING AB TO B-INTERFERO

LAB3120

 

Collect

One 7 mL red top with gel. [Min vol: 5 mL].

Unacceptable Conditions

.

Storage/Transport Temperature

Internal: Deliver to lab immediately
Offsite: 2 mL serum Deliver to lab, if delayed, pouroff serum into plastic pouroff tube & refrigerate. Ship to reference lab within 24 hours of collection. Samples shipped M-F.

Stability (from collection to initiation)

Refrigerated:

Remarks

Sample needs to be collected either before treatment with interferon or more than 24 hours following the most recent dose. Patient should not be on steroid therapy for at least two weeks prior to testing.

Performed by

Athena Diagnostics

Performed

Tue, Wed

Methodology

Viral cytopathic effect assay

Reported

In 14 days

Synonyms

  • LAB3120
  • NABFERON
  • NEUTRALIZING

Performed by

Athena Diagnostics

CPT Codes

87253(1), 86382(1)

Collection

LAB3120

 

Collect

One 7 mL red top with gel. [Min vol: 5 mL].

Unacceptable Conditions

.

Storage/Transport Temperature

Internal: Deliver to lab immediately
Offsite: 2 mL serum Deliver to lab, if delayed, pouroff serum into plastic pouroff tube & refrigerate. Ship to reference lab within 24 hours of collection. Samples shipped M-F.

Stability (from collection to initiation)

Refrigerated:

Remarks

Sample needs to be collected either before treatment with interferon or more than 24 hours following the most recent dose. Patient should not be on steroid therapy for at least two weeks prior to testing.

Performed by

Athena Diagnostics

Ordering

Performed

Tue, Wed

Methodology

Viral cytopathic effect assay

Reported

In 14 days

Synonyms

  • LAB3120
  • NABFERON
  • NEUTRALIZING
Result Interpretation

Performed by

Athena Diagnostics

Administrative

CPT Codes

87253(1), 86382(1)

NEUTROPHIL ANTIBODY, INDIRECT

LAB1176

 

Collect

Plain red or serum separator tube.

Specimen Preparation

Remove serum from cells ASAP or within 2 hours of collection.  Transfer 3 mL serum to an ARUP Standard Transport Tube and freeze. (Min: 0.5 mL)

Storage/Transport Temperature

Frozen (on dry ice).

Stability (from collection to initiation)

After separation from cells: Ambient: Unacceptable; Refrigerated: Unacceptable; Frozen: 1 month

Notes

Circulating antibodies in patient's serum are measured by flow cytometry after incubation with normal neutrophils. Values greater than 2 standard deviations of a normal control population are interpreted as "weakly positive" and greater than 3 standard deviations as "positive".

This test should not be confused with Anti-Neutrophil Cytoplasmic Antibody, IgG (0050811 - ANCA).

Performed

Mon, Thu

Methodology

Qualitative Flow Cytometry

Reported

1-5 days

Synonyms

  • Granulocyte Antibody
  • Anti-Granulocyte Antibody
  • Neutrophil Antibody
  • Anti-Neutrophil Antibody
  • LAB1176
  • NEUT AB

Ordering Recommendations

Support the diagnosis of immune neutropenia in various autoimmune disorders.

Reference Interval

Negative

Interpretive Data

Neutrophil-associated antibodies may cause neutropenia in various autoimmune disorders including Felty syndrome, SLE and drug-induced neutropenia.  Febrile transfusion reactions and isoimmune neonatal neutropenia may also be caused by antibodies to neutrophil-specific antigens or HLA antigens.

A positive result on this test is not definitive for specific anti-neutrophil antibodies, since anti-HLA antibodies and immune complexes may also cause a positive result.  The results of this test should be correlated to clinical history and other data.

CPT Codes

86021
Collection

LAB1176

 

Collect

Plain red or serum separator tube.

Specimen Preparation

Remove serum from cells ASAP or within 2 hours of collection.  Transfer 3 mL serum to an ARUP Standard Transport Tube and freeze. (Min: 0.5 mL)

Storage/Transport Temperature

Frozen (on dry ice).

Stability (from collection to initiation)

After separation from cells: Ambient: Unacceptable; Refrigerated: Unacceptable; Frozen: 1 month

Notes

Circulating antibodies in patient's serum are measured by flow cytometry after incubation with normal neutrophils. Values greater than 2 standard deviations of a normal control population are interpreted as "weakly positive" and greater than 3 standard deviations as "positive".

This test should not be confused with Anti-Neutrophil Cytoplasmic Antibody, IgG (0050811 - ANCA).
Ordering

Performed

Mon, Thu

Methodology

Qualitative Flow Cytometry

Reported

1-5 days

Synonyms

  • Granulocyte Antibody
  • Anti-Granulocyte Antibody
  • Neutrophil Antibody
  • Anti-Neutrophil Antibody
  • LAB1176
  • NEUT AB

Ordering Recommendations

Support the diagnosis of immune neutropenia in various autoimmune disorders.
Result Interpretation

Reference Interval

Negative

Interpretive Data

Neutrophil-associated antibodies may cause neutropenia in various autoimmune disorders including Felty syndrome, SLE and drug-induced neutropenia.  Febrile transfusion reactions and isoimmune neonatal neutropenia may also be caused by antibodies to neutrophil-specific antigens or HLA antigens.

A positive result on this test is not definitive for specific anti-neutrophil antibodies, since anti-HLA antibodies and immune complexes may also cause a positive result.  The results of this test should be correlated to clinical history and other data.

Administrative

CPT Codes

86021

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