Tests Catalogs

HLA CELIAC PANEL

LAB3673

 

Collect

Update 10/19/15:

5 mL Purple EDTA Whole Blood. Also acceptable:

10 mL yellow top (ACD-A) whole blood

Remarks

Samples should be processed at ClinImmune within 24 hours of collection. Maintain specimens at room temperature. Do not refrigerate.

Celiac HLA Panel:  HLA-DQ2, HLA-DQ8, HLA-DQA1*05

Performed by

Clinimmune Labs

Performed

Upon receipt.

Methodology

HLA-DQB1 identification by high resolution technique

Synonyms

  • Genetic Celiac Panel
  • LAB3673

Performed by

Clinimmune Labs

CPT Codes

81382

Collection

LAB3673

 

Collect

Update 10/19/15:

5 mL Purple EDTA Whole Blood. Also acceptable:

10 mL yellow top (ACD-A) whole blood

Remarks

Samples should be processed at ClinImmune within 24 hours of collection. Maintain specimens at room temperature. Do not refrigerate.

Celiac HLA Panel:  HLA-DQ2, HLA-DQ8, HLA-DQA1*05

Performed by

Clinimmune Labs

Ordering

Performed

Upon receipt.

Methodology

HLA-DQB1 identification by high resolution technique

Synonyms

  • Genetic Celiac Panel
  • LAB3673
Result Interpretation

Performed by

Clinimmune Labs

Administrative

CPT Codes

81382

HLA CLASS I SINGLE ANTIGEN

Collect

One 10 mL yellow (ACD) - whole blood

Storage/Transport Temperature

Internal: Deliver to lab immediatley
Offsite: Deliver to lab at room temperature.

Remarks

HLA Class I antigen to be tested for must be specified on the requisition/paperwork submitted with sample.

Performed by

Clinimmune Labs

Performed by

Clinimmune Labs

CPT Codes

81373

Collection

Collect

One 10 mL yellow (ACD) - whole blood

Storage/Transport Temperature

Internal: Deliver to lab immediatley
Offsite: Deliver to lab at room temperature.

Remarks

HLA Class I antigen to be tested for must be specified on the requisition/paperwork submitted with sample.

Performed by

Clinimmune Labs

Ordering
Result Interpretation

Performed by

Clinimmune Labs

Administrative

CPT Codes

81373

HLA CLASS II SINGLE ANTIGEN

Collect

One 10 mL yellow (ACD) - whole blood

Storage/Transport Temperature

Internal: Deliver to lab immediatley
Offsite: Deliver to lab at room temperature.

Remarks

HLA Class I antigen to be tested for must be specified on the requisition/paperwork submitted with sample.

Performed by

Clinimmune Labs

Performed by

Clinimmune Labs

CPT Codes

81373

Collection

Collect

One 10 mL yellow (ACD) - whole blood

Storage/Transport Temperature

Internal: Deliver to lab immediatley
Offsite: Deliver to lab at room temperature.

Remarks

HLA Class I antigen to be tested for must be specified on the requisition/paperwork submitted with sample.

Performed by

Clinimmune Labs

Ordering
Result Interpretation

Performed by

Clinimmune Labs

Administrative

CPT Codes

81373

HLA SINGLE SPECIFIC HLA-B51

LAB3674

Collect

Update 10/19/15:

5 mL Purple EDTA Whole Blood. Also acceptable:

10 mL yellow top (ACD-A) whole blood

Unacceptable Conditions

Wrong tube, refrigerated specimen, non-whole blood specimens. EDTA is not acceptable for this test.

Storage/Transport Temperature

Internal:

Deliver to lab immediately

External:

Deliver to lab at room temperature

Remarks

Samples should be processed by ClinImmune within 24 hours of collection. Maintain specimen at room temperature. Do not refrigerate.

Performed by

Clinimmune Labs

Performed

Upon receipt.

Methodology

Separation and identification by low resolution technique

Reported

In 2 days.

Synonyms

  • Behcet's Disease HLA Test
  • LAB3674
  • HLAB51

Performed by

Clinimmune Labs

CPT Codes

81373

Collection

LAB3674

Collect

Update 10/19/15:

5 mL Purple EDTA Whole Blood. Also acceptable:

10 mL yellow top (ACD-A) whole blood

Unacceptable Conditions

Wrong tube, refrigerated specimen, non-whole blood specimens. EDTA is not acceptable for this test.

Storage/Transport Temperature

Internal:

Deliver to lab immediately

External:

Deliver to lab at room temperature

Remarks

Samples should be processed by ClinImmune within 24 hours of collection. Maintain specimen at room temperature. Do not refrigerate.

Performed by

Clinimmune Labs

Ordering

Performed

Upon receipt.

Methodology

Separation and identification by low resolution technique

Reported

In 2 days.

Synonyms

  • Behcet's Disease HLA Test
  • LAB3674
  • HLAB51
Result Interpretation

Performed by

Clinimmune Labs

Administrative

CPT Codes

81373

HLA-SINGLE SPECIFIC HLA-B27

LAB869

Collect

Update 10/19/15:

5 mL Purple EDTA Whole Blood. Also acceptable:

10 mL yellow top (ACD-A) whole blood

Unacceptable Conditions

Wrong tube, refrigerated specimen, non-whole blood specimens. EDTA whole blood not acceptable for this test.

Storage/Transport Temperature

Internal: Deliver to lab immediatley
Offsite: Deliver to lab at room temperature.

Stability (from collection to initiation)

.

Remarks

Sample should be processed within 24 hours of collection. Maintain specimen at room temperature; do not refrigerate.

Performed by

Clinimmune Labs

Performed

Upon receipt

Methodology

Separation and identification by low resolution technique

Reported

In 2 days

Synonyms

  • LAB869
  • HLAB27

Performed by

Clinimmune Labs

CPT Codes

81373

Collection

LAB869

Collect

Update 10/19/15:

5 mL Purple EDTA Whole Blood. Also acceptable:

10 mL yellow top (ACD-A) whole blood

Unacceptable Conditions

Wrong tube, refrigerated specimen, non-whole blood specimens. EDTA whole blood not acceptable for this test.

Storage/Transport Temperature

Internal: Deliver to lab immediatley
Offsite: Deliver to lab at room temperature.

Stability (from collection to initiation)

.

Remarks

Sample should be processed within 24 hours of collection. Maintain specimen at room temperature; do not refrigerate.

Performed by

Clinimmune Labs

Ordering

Performed

Upon receipt

Methodology

Separation and identification by low resolution technique

Reported

In 2 days

Synonyms

  • LAB869
  • HLAB27
Result Interpretation

Performed by

Clinimmune Labs

Administrative

CPT Codes

81373

HLA-SINGLE SPECIFIC HLA-B5701

LAB3515

Collect

Update 10/19/15:

5 mL Purple EDTA Whole Blood. Also acceptable:

10 mL yellow top (ACD-A) whole blood

Unacceptable Conditions

Frozen samples. Serum/plasma.

Storage/Transport Temperature

Internal: Deliver to lab immediatley
Offsite: 5 mL EDTA whole blood Ship to lab at room temperature.

Stability (from collection to initiation)

Ambient: 5 days

Remarks

Deliver to reference lab within 24 hours of collection. Samples up to 5 days old are acceptable. Store at room temp.

 

For Infectious Disease purposes, if HLAB*5701 is PRESENT a patient may need to avoid a specific medication.

Performed by

Clinimmune Labs

Performed

Varies

Reported

7 - 10 days

Synonyms

  • LAB3515
  • HLAB5701

Performed by

Clinimmune Labs

CPT Codes

81380 

 

 

 

 

Collection

LAB3515

Collect

Update 10/19/15:

5 mL Purple EDTA Whole Blood. Also acceptable:

10 mL yellow top (ACD-A) whole blood

Unacceptable Conditions

Frozen samples. Serum/plasma.

Storage/Transport Temperature

Internal: Deliver to lab immediatley
Offsite: 5 mL EDTA whole blood Ship to lab at room temperature.

Stability (from collection to initiation)

Ambient: 5 days

Remarks

Deliver to reference lab within 24 hours of collection. Samples up to 5 days old are acceptable. Store at room temp.

 

For Infectious Disease purposes, if HLAB*5701 is PRESENT a patient may need to avoid a specific medication.

Performed by

Clinimmune Labs

Ordering

Performed

Varies

Reported

7 - 10 days

Synonyms

  • LAB3515
  • HLAB5701
Result Interpretation

Performed by

Clinimmune Labs

Administrative

CPT Codes

81380 

 

 

 

 

HOMOCYSTEINE, PLASMA

LAB3016

Collect

One 4.0 mL purple top (EDTA), placed immediately on ice.

Pediatric Collection

Minimum volume: 1.0 mL EDTA plasma.

Unacceptable Conditions

Specimen improperly stored (not on ice); clotted sample; grossly hemolyzed sample; obvious microbial contamination; heat-inactivated sample; cadaver sample; other body fluids; specimen not properly identified; incorrect container; insufficient sample volume.

Storage/Transport Temperature

Internal: Deliver to lab immediately on ice/cold pack.
Offsite: Centrifuge within 6 hours of collection. Keep refrigerated/on ice (2-8 degrees C).  Place at least 1.0 mL of EDTA plasma in an aliquot container and transport to lab refrigerated/on ice.

Stability (from collection to initiation)

Whole blood: Ambient, unacceptable; Refrigerated/on ice (2-8 degrees C), 6 hours; Frozen, unacceptable.

Plasma aliquot: Ambient, unacceptable; Refrigerated (2-8 degrees C), 14 days; Frozen (-20 degrees C), 1 year.

Remarks

Specimen must remain refrigerated/on ice (2-8 degrees C) to prevent continued synthesis of Homocysteine.  Sample can remain on ice up to 6 hours.

This test is an indicator of Cardiac Risk.

Performed by

PCL Clinical Laboratory - Toxicology

Performed

Wed

Methodology

Chemiluminescent Microparticle Immunoassay (CMIA)

Reported

Same day

Synonyms

  • LAB3016
  • HOMOC

Reference Interval

5.0-15.0 umol/L

Performed by

PCL Clinical Laboratory - Toxicology

CPT Codes

83090

Collection

LAB3016

Collect

One 4.0 mL purple top (EDTA), placed immediately on ice.

Pediatric Collection

Minimum volume: 1.0 mL EDTA plasma.

Unacceptable Conditions

Specimen improperly stored (not on ice); clotted sample; grossly hemolyzed sample; obvious microbial contamination; heat-inactivated sample; cadaver sample; other body fluids; specimen not properly identified; incorrect container; insufficient sample volume.

Storage/Transport Temperature

Internal: Deliver to lab immediately on ice/cold pack.
Offsite: Centrifuge within 6 hours of collection. Keep refrigerated/on ice (2-8 degrees C).  Place at least 1.0 mL of EDTA plasma in an aliquot container and transport to lab refrigerated/on ice.

Stability (from collection to initiation)

Whole blood: Ambient, unacceptable; Refrigerated/on ice (2-8 degrees C), 6 hours; Frozen, unacceptable.

Plasma aliquot: Ambient, unacceptable; Refrigerated (2-8 degrees C), 14 days; Frozen (-20 degrees C), 1 year.

Remarks

Specimen must remain refrigerated/on ice (2-8 degrees C) to prevent continued synthesis of Homocysteine.  Sample can remain on ice up to 6 hours.

This test is an indicator of Cardiac Risk.

Performed by

PCL Clinical Laboratory - Toxicology

Ordering

Performed

Wed

Methodology

Chemiluminescent Microparticle Immunoassay (CMIA)

Reported

Same day

Synonyms

  • LAB3016
  • HOMOC
Result Interpretation

Reference Interval

5.0-15.0 umol/L

Performed by

PCL Clinical Laboratory - Toxicology

Administrative

CPT Codes

83090

HOMOVANILLIC ACID URINE

LAB401

Collect

24-hour or random urine. Refrigerate 24-hour specimens during collection.

Patient Preparation

Abstain from medications for 72 hours prior to collection.

Specimen Preparation

Transfer 4 mL aliquot from a well-mixed 24-hour or random collection to an ARUP Standard Transport Tube. (Min: 1 mL) Record total volume and collection time interval on transport tube and test request form.

Unacceptable Conditions

Specimen types other than urine.

Storage/Transport Temperature

Refrigerated.

Stability (from collection to initiation)

Ambient: Unacceptable; Refrigerated: 1 week; Frozen: 2 weeks

Notes

Moderately elevated HVA (homovanillic acid) may be caused by a variety of factors such as essential hypertension, intense anxiety, intense physical exercise, and numerous drug interactions (including some over-the-counter medications and herbal products).

Medications that may interfere with catecholamines and their metabolites include amphetamines and amphetamine-like compounds, appetite suppressants, bromocriptine, buspirone, caffeine, chlorpromazine, clonidine, disulfiram, diuretics (in doses sufficient to deplete sodium), epinephrine, glucagon, guanethidine, histamine, hydrazine derivatives, imipramine, levodopa (L-dopa, Sinemet®), lithium, MAO inhibitors, melatonin, methyldopa (Aldomet®), morphine, nitroglycerin, nose drops, propafenone (Rythmol), radiographic agents, rauwolfia alkaloids (Reserpine), and vasodilators.  The effects of some drugs on catecholamine metabolite results may not be predictable.

Performed

Sun, Tue-Sat

Methodology

Quantitative High Performance Liquid Chromatography-Tandem Mass Spectrometry

Reported

1-4 days

Synonyms

  • 3-Methoxy-4-Hydroxy Phenylacetic Acid, Urine
  • HVA, Urine
  • Homovanillic Acid, Urine
  • LAB401
  • HVA
  • HVAU

Ordering Recommendations

Initial test for the diagnosis and monitoring of neuroblastoma; order concurrently with Vanillylmandelic Acid (VMA), Urine (0080421).

Reference Interval

Effective May 19, 2014
Components
Reference Interval
Homovanillic Acid - per 24h18 years and older: 0.0-15.0 mg/d
Homovanillic Acid - ratio to CRTThe HVA-to-creatinine ratio will be reported when the patient is under 18 years, the urine collection is random or other than 24 hours, or the urine volume is less than 400 mL/24 hours.
Age
Reference Interval
0-2 years0-42 mg/g CRT
3-5 years0-22 mg/g CRT
6-17 years0-15 mg/g CRT
18 years and older0-8 mg/g CRT

Creatinine, Urine - per 24h
AgeMaleFemale
3-8 years140-700 mg/d140-700 mg/d
9-12 years300-1300 mg/d300-1300 mg/d
13-17 years500-2300 mg/d400-1600 mg/d
18-50 years1000-2500 mg/d700-1600 mg/d
51-80 years800-2100 mg/d500-1400 mg/d
81 years and older600-2000 mg/d400-1300 mg/d


Interpretive Data

Homovanillic acid (HVA) results are expressed as a ratio to creatinine excretion (mg/g CRT). HVA mass per day (mg/d) is not reported on specimens from patients younger than 18 years of age, or for random specimens, urine collection periods other than 24 hours, or urine volumes less than 400 mL/d. No reference interval is available for results reported in units of mg/L. Slight or moderate increases in catecholamine metabolites may be due to extreme anxiety, essential hypertension, intense physical exercise, or drug interactions. Significant increase of one or more catecholamine metabolites (several times the upper reference limit) is associated with an increased probability of a secreting neuroendocrine tumor.

CPT Codes

83150
Collection

LAB401

Collect

24-hour or random urine. Refrigerate 24-hour specimens during collection.

Patient Preparation

Abstain from medications for 72 hours prior to collection.

Specimen Preparation

Transfer 4 mL aliquot from a well-mixed 24-hour or random collection to an ARUP Standard Transport Tube. (Min: 1 mL) Record total volume and collection time interval on transport tube and test request form.

Unacceptable Conditions

Specimen types other than urine.

Storage/Transport Temperature

Refrigerated.

Stability (from collection to initiation)

Ambient: Unacceptable; Refrigerated: 1 week; Frozen: 2 weeks

Notes

Moderately elevated HVA (homovanillic acid) may be caused by a variety of factors such as essential hypertension, intense anxiety, intense physical exercise, and numerous drug interactions (including some over-the-counter medications and herbal products).

Medications that may interfere with catecholamines and their metabolites include amphetamines and amphetamine-like compounds, appetite suppressants, bromocriptine, buspirone, caffeine, chlorpromazine, clonidine, disulfiram, diuretics (in doses sufficient to deplete sodium), epinephrine, glucagon, guanethidine, histamine, hydrazine derivatives, imipramine, levodopa (L-dopa, Sinemet®), lithium, MAO inhibitors, melatonin, methyldopa (Aldomet®), morphine, nitroglycerin, nose drops, propafenone (Rythmol), radiographic agents, rauwolfia alkaloids (Reserpine), and vasodilators.  The effects of some drugs on catecholamine metabolite results may not be predictable.
Ordering

Performed

Sun, Tue-Sat

Methodology

Quantitative High Performance Liquid Chromatography-Tandem Mass Spectrometry

Reported

1-4 days

Synonyms

  • 3-Methoxy-4-Hydroxy Phenylacetic Acid, Urine
  • HVA, Urine
  • Homovanillic Acid, Urine
  • LAB401
  • HVA
  • HVAU

Ordering Recommendations

Initial test for the diagnosis and monitoring of neuroblastoma; order concurrently with Vanillylmandelic Acid (VMA), Urine (0080421).
Result Interpretation

Reference Interval

Effective May 19, 2014
Components
Reference Interval
Homovanillic Acid - per 24h18 years and older: 0.0-15.0 mg/d
Homovanillic Acid - ratio to CRTThe HVA-to-creatinine ratio will be reported when the patient is under 18 years, the urine collection is random or other than 24 hours, or the urine volume is less than 400 mL/24 hours.
Age
Reference Interval
0-2 years0-42 mg/g CRT
3-5 years0-22 mg/g CRT
6-17 years0-15 mg/g CRT
18 years and older0-8 mg/g CRT

Creatinine, Urine - per 24h
AgeMaleFemale
3-8 years140-700 mg/d140-700 mg/d
9-12 years300-1300 mg/d300-1300 mg/d
13-17 years500-2300 mg/d400-1600 mg/d
18-50 years1000-2500 mg/d700-1600 mg/d
51-80 years800-2100 mg/d500-1400 mg/d
81 years and older600-2000 mg/d400-1300 mg/d


Interpretive Data

Homovanillic acid (HVA) results are expressed as a ratio to creatinine excretion (mg/g CRT). HVA mass per day (mg/d) is not reported on specimens from patients younger than 18 years of age, or for random specimens, urine collection periods other than 24 hours, or urine volumes less than 400 mL/d. No reference interval is available for results reported in units of mg/L. Slight or moderate increases in catecholamine metabolites may be due to extreme anxiety, essential hypertension, intense physical exercise, or drug interactions. Significant increase of one or more catecholamine metabolites (several times the upper reference limit) is associated with an increased probability of a secreting neuroendocrine tumor.

Administrative

CPT Codes

83150

HSV TYPE 1 & 2 SPECIFIC AB IGG

LAB3226

HSV TYPE 1&2

Collect

One 4.5 mL Gold or Red top tube with gel (SST), clot activator serum.

Pediatric Collection

Minimum volume: 1 mL whole blood or 500 uL serum

Unacceptable Conditions

Sample not properly identified; incorrect container; insufficient sample volume; grossly hemolyzed or lipemic samples.

Storage/Transport Temperature

Internal: Deliver to lab immediately.
Offsite: Allow to clot in an upright position for 30 minutes, centrifuge and remove serum from cells within 1 hour of collection. Place serum in an aliquot container and send refrigerated or frozen.

Stability (from collection to initiation)

Whole blood: Ambient, 1 hour.

Serum aliquot: Ambient, 8 hours; Refrigerated, 7 days; Frozen (-20 degrees C), 1 month.

Performed by

PCL Clinical Laboratory - Special Chemistry

Performed

Fridays

Methodology

Chemiluminescent immunology, type-specific for HSV-1 and HSV-2 IgG antibodies.

Reported

Same day

Synonyms

  • LAB3226

Reference Interval

Negative

Performed by

PCL Clinical Laboratory - Special Chemistry

CPT Codes

86695; 86696

Collection

LAB3226

HSV TYPE 1&2

Collect

One 4.5 mL Gold or Red top tube with gel (SST), clot activator serum.

Pediatric Collection

Minimum volume: 1 mL whole blood or 500 uL serum

Unacceptable Conditions

Sample not properly identified; incorrect container; insufficient sample volume; grossly hemolyzed or lipemic samples.

Storage/Transport Temperature

Internal: Deliver to lab immediately.
Offsite: Allow to clot in an upright position for 30 minutes, centrifuge and remove serum from cells within 1 hour of collection. Place serum in an aliquot container and send refrigerated or frozen.

Stability (from collection to initiation)

Whole blood: Ambient, 1 hour.

Serum aliquot: Ambient, 8 hours; Refrigerated, 7 days; Frozen (-20 degrees C), 1 month.

Performed by

PCL Clinical Laboratory - Special Chemistry

Ordering

Performed

Fridays

Methodology

Chemiluminescent immunology, type-specific for HSV-1 and HSV-2 IgG antibodies.

Reported

Same day

Synonyms

  • LAB3226
Result Interpretation

Reference Interval

Negative

Performed by

PCL Clinical Laboratory - Special Chemistry

Administrative

CPT Codes

86695; 86696

HSV TYPE 1 AND/OR 2 ABS - IGM

LAB655

Collect

Serum separator tube.

Specimen Preparation

Separate serum from cells ASAP or within 2 hours of collection. Transfer 0.5 mL serum to an ARUP Standard Transport Tube. (Min: 0.1 mL) Parallel testing is preferred and convalescent specimens must be received within 30 days from receipt of the acute specimens. Mark specimens plainly as "acute" or convalescent."

Unacceptable Conditions

Contaminated, heat-inactivated, hemolyzed, icteric, or severely lipemic specimens.

Storage/Transport Temperature

Refrigerated.

Stability (from collection to initiation)

After separation from cells: Ambient: 48 hours; Refrigerated: 2 weeks; Frozen: 1 year (avoid repeated freeze/thaw cycles)

Performed

Sun-Sat

Methodology

Semi-Quantitative Enzyme-Linked Immunosorbent Assay

Reported

Within 24 hours

Synonyms

  • LAB655
  • HERPI/II M

Ordering Recommendations

Not recommended for herpes simplex virus (HSV) testing; IgM lacks adequate predictive value for acute infection. If pursuing antibody testing, refer to Herpes Simplex Type 1 and Type 2 Glycoprotein G-Specific Antibodies, IgG by CIA (0051152). If acute HSV infection is suspected, molecular testing is preferred (refer to Herpes Simplex Virus by PCR (0060041)).

Reference Interval

0.89 IV or less:Not Detected.
0.90-1.09 IV:Indeterminate - Repeat testing in 10-14 days may be helpful.
1.10 IV or greater:Detected - IgM antibody to HSV detected, which may indicate a current or recent infection. However, low levels of IgM antibodies may occasionally persist for more than 12 months post-infection.

CPT Codes

86694
Collection

LAB655

Collect

Serum separator tube.

Specimen Preparation

Separate serum from cells ASAP or within 2 hours of collection. Transfer 0.5 mL serum to an ARUP Standard Transport Tube. (Min: 0.1 mL) Parallel testing is preferred and convalescent specimens must be received within 30 days from receipt of the acute specimens. Mark specimens plainly as "acute" or convalescent."

Unacceptable Conditions

Contaminated, heat-inactivated, hemolyzed, icteric, or severely lipemic specimens.

Storage/Transport Temperature

Refrigerated.

Stability (from collection to initiation)

After separation from cells: Ambient: 48 hours; Refrigerated: 2 weeks; Frozen: 1 year (avoid repeated freeze/thaw cycles)
Ordering

Performed

Sun-Sat

Methodology

Semi-Quantitative Enzyme-Linked Immunosorbent Assay

Reported

Within 24 hours

Synonyms

  • LAB655
  • HERPI/II M

Ordering Recommendations

Not recommended for herpes simplex virus (HSV) testing; IgM lacks adequate predictive value for acute infection. If pursuing antibody testing, refer to Herpes Simplex Type 1 and Type 2 Glycoprotein G-Specific Antibodies, IgG by CIA (0051152). If acute HSV infection is suspected, molecular testing is preferred (refer to Herpes Simplex Virus by PCR (0060041)).
Result Interpretation

Reference Interval

0.89 IV or less:Not Detected.
0.90-1.09 IV:Indeterminate - Repeat testing in 10-14 days may be helpful.
1.10 IV or greater:Detected - IgM antibody to HSV detected, which may indicate a current or recent infection. However, low levels of IgM antibodies may occasionally persist for more than 12 months post-infection.

Administrative

CPT Codes

86694

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