KAPPA:LAMBDA FREE LIGHT CHAINS BLOOD

LAB3221

KAP:LAM LC

Collect

One 5.0 mL Red top or Gold top with gel (SST), clot activator serum.

Pediatric Collection

Minimum volume: 0.5 mL serum.

Unacceptable Conditions

Any plasma sample; gross lipemia or hemolysis; sample not properly identified; incorrect container; insufficient sample volume.

Storage/Transport Temperature

Internal: Allow to clot for 30 minutes, then deliver to lab immediately at ambient temperature.
Offsite: Allow blood to clot for 30 minutes prior to centrifugation. Centrifuge within 1 hour of collection. Transport to laboratory at 2-8 degrees C.

Stability (from collection to initiation)

Before centrifugation: Ambient, 1 hour.

After centrifugation: Ambient: 1 hour; Refrigerated: 24 hours; Frozen : Unacceptable.

Serum aliquot: Ambient, 1 hour; Refrigerated, 21 days; Frozen (-20 degrees C): 3 months.

Performed by

PCL Clinical Laboratory - Special Chemistry

Notes

Due to the half-life of the protein in the system, any Kappa:Lambda order that is placed within 20 hours of the previous Kappa:Lambda level will be considered a duplicate order and will be cancelled.

Performed

Monday and Thursday

Methodology

Nephelometry

Reported

Same day

Synonyms

  • LAB3221
  • KAP/LAM F
  • KAP:LAB LC

Reference Interval

Note: The reference range for the Kappa/Lambda Free Light Chain ratio does not apply to patients with kidney failure or a very low glomerular filtration rate.

Component Sex From Age To Age Normal Low Normal High Units
KAPPA QNT FREE LIGHT CHAINS M/F 0 150 0.69 2.34 mg/dL
KAPPA:LAMBDA FREE L/C RATIO M/F 0 150 0.58 2.24  
LAMBDA QNT FREE LIGHT CHAINS M/F 0 150 0.51 2.75 mg/dL

Performed by

PCL Clinical Laboratory - Special Chemistry

CPT Codes

83883 (2)

Collection

LAB3221

KAP:LAM LC

Collect

One 5.0 mL Red top or Gold top with gel (SST), clot activator serum.

Pediatric Collection

Minimum volume: 0.5 mL serum.

Unacceptable Conditions

Any plasma sample; gross lipemia or hemolysis; sample not properly identified; incorrect container; insufficient sample volume.

Storage/Transport Temperature

Internal: Allow to clot for 30 minutes, then deliver to lab immediately at ambient temperature.
Offsite: Allow blood to clot for 30 minutes prior to centrifugation. Centrifuge within 1 hour of collection. Transport to laboratory at 2-8 degrees C.

Stability (from collection to initiation)

Before centrifugation: Ambient, 1 hour.

After centrifugation: Ambient: 1 hour; Refrigerated: 24 hours; Frozen : Unacceptable.

Serum aliquot: Ambient, 1 hour; Refrigerated, 21 days; Frozen (-20 degrees C): 3 months.

Performed by

PCL Clinical Laboratory - Special Chemistry

Notes

Due to the half-life of the protein in the system, any Kappa:Lambda order that is placed within 20 hours of the previous Kappa:Lambda level will be considered a duplicate order and will be cancelled.

Ordering

Performed

Monday and Thursday

Methodology

Nephelometry

Reported

Same day

Synonyms

  • LAB3221
  • KAP/LAM F
  • KAP:LAB LC
Result Interpretation

Reference Interval

Note: The reference range for the Kappa/Lambda Free Light Chain ratio does not apply to patients with kidney failure or a very low glomerular filtration rate.

Component Sex From Age To Age Normal Low Normal High Units
KAPPA QNT FREE LIGHT CHAINS M/F 0 150 0.69 2.34 mg/dL
KAPPA:LAMBDA FREE L/C RATIO M/F 0 150 0.58 2.24  
LAMBDA QNT FREE LIGHT CHAINS M/F 0 150 0.51 2.75 mg/dL

Performed by

PCL Clinical Laboratory - Special Chemistry

Administrative

CPT Codes

83883 (2)

KENNEDY'S DISEASE DNA TEST

LAB3198

 

Collect

Two 5 mL purple top (EDTA) - whole blood

Unacceptable Conditions

Non EDTA whole blood; plasma; serum

Storage/Transport Temperature

Internal: Deliver to lab immediatley
Offsite: 5 mL EDTA whole blood Deliver to lab at ambient temperaure.

Stability (from collection to initiation)

5-7 days

Remarks

Testing for Spinal and Bulbar Muscular Atrophy [SBMA]. An X-linked recessive disease.
Shipped Mon-Thurs only.

Performed by

Baylor College of Medicine - Medical Genetics Laboratories

Performed

Varies

Methodology

Direct Mutation Analysis [PCR]

Reported

2 - 4 weeks

Reference Interval

No mutation detected.

Performed by

Baylor College of Medicine - Medical Genetics Laboratories

CPT Codes

81401

Collection

LAB3198

 

Collect

Two 5 mL purple top (EDTA) - whole blood

Unacceptable Conditions

Non EDTA whole blood; plasma; serum

Storage/Transport Temperature

Internal: Deliver to lab immediatley
Offsite: 5 mL EDTA whole blood Deliver to lab at ambient temperaure.

Stability (from collection to initiation)

5-7 days

Remarks

Testing for Spinal and Bulbar Muscular Atrophy [SBMA]. An X-linked recessive disease.
Shipped Mon-Thurs only.

Performed by

Baylor College of Medicine - Medical Genetics Laboratories

Ordering

Performed

Varies

Methodology

Direct Mutation Analysis [PCR]

Reported

2 - 4 weeks

Result Interpretation

Reference Interval

No mutation detected.

Performed by

Baylor College of Medicine - Medical Genetics Laboratories

Administrative

CPT Codes

81401

KEPPRA (LEVETIRACETAM)

LAB477

KEPPRA

 

Collect

One 6 mL plain red top tube, no gel.

Pediatric Collection

Minimum volume: 0.5 mL serum

Unacceptable Conditions

Sample submitted in gel separator tube; sample not properly identified; incorrect container; insufficient sample volume.

Storage/Transport Temperature

Internal:  Deliver to lab immediately.
Offsite: 
Allow 30 minutes for red top to clot before centrifuging. Centrifuge within 2 hours of collection. Place at least 0.5 mL serum in aliquot container and send to lab refrigerated/on ice (2-8 °C).

Stability (from collection to initiation)

Prior to centrifugation: Ambient, 2 hours.

Serum aliquot: Ambient, 6 weeks; Refrigerated (2-8 degrees C), 6 weeks; Frozen (-20 degrees C): 6 weeks

Remarks

For best results with patients receiving chronic therapy, obtain a steady-state trough (pre-dose) blood sample.

Performed by

PCL Clinical Laboratory - Toxicology

Performed

Monday and Thursday

Methodology

High Performance Liquid Chromatography

Reported

Same day

Synonyms

  • Levetiracetam
  • LAB477

Reference Interval

Therapeutic range: Not well established

Interpretive Data

The effective serum levels for levetiracetam vary among individuals.  12 to 46 µg/mL has been reported as a range over which some have responded to the drug based on a specimen drawn immediately before the next dose.  It is also common for individuals to have a therapeutic response with a level outside this range.  Therefore, interpretation of this result must be made in the context of the individual clinical scenario. 

Performed by

PCL Clinical Laboratory - Toxicology

CPT Codes

80177

Collection

LAB477

KEPPRA

 

Collect

One 6 mL plain red top tube, no gel.

Pediatric Collection

Minimum volume: 0.5 mL serum

Unacceptable Conditions

Sample submitted in gel separator tube; sample not properly identified; incorrect container; insufficient sample volume.

Storage/Transport Temperature

Internal:  Deliver to lab immediately.
Offsite: 
Allow 30 minutes for red top to clot before centrifuging. Centrifuge within 2 hours of collection. Place at least 0.5 mL serum in aliquot container and send to lab refrigerated/on ice (2-8 °C).

Stability (from collection to initiation)

Prior to centrifugation: Ambient, 2 hours.

Serum aliquot: Ambient, 6 weeks; Refrigerated (2-8 degrees C), 6 weeks; Frozen (-20 degrees C): 6 weeks

Remarks

For best results with patients receiving chronic therapy, obtain a steady-state trough (pre-dose) blood sample.

Performed by

PCL Clinical Laboratory - Toxicology

Ordering

Performed

Monday and Thursday

Methodology

High Performance Liquid Chromatography

Reported

Same day

Synonyms

  • Levetiracetam
  • LAB477
Result Interpretation

Reference Interval

Therapeutic range: Not well established

Interpretive Data

The effective serum levels for levetiracetam vary among individuals.  12 to 46 µg/mL has been reported as a range over which some have responded to the drug based on a specimen drawn immediately before the next dose.  It is also common for individuals to have a therapeutic response with a level outside this range.  Therefore, interpretation of this result must be made in the context of the individual clinical scenario. 

Performed by

PCL Clinical Laboratory - Toxicology

Administrative

CPT Codes

80177

KETONES SERUM

LAB44

KETONE,S

 

Collect

One 4.5 mL Red top or Gold top tube with gel separator (SST).

Pediatric Collection

0.5 mL serum.

Unacceptable Conditions

Sample not properly identified; incorrect container; insufficient sample volume.

Storage/Transport Temperature

Internal: Deliver to lab immediately.
Offsite: Allow to clot for 20 minutes before centrifugation. Centrifuge within two hours of collection. Send at 2-8 degrees C.

Stability (from collection to initiation)

Ambient: 4 hours; Refrigerated: 48 hours; Frozen: Unacceptable.

Remarks

This is a semiquantitative method using acetest tablets to detect the presence of ketone bodies, acetoacetic acid, and acetone.  Does not detect betahydroxybutyric acid and is not specific for any one ketone.

Performed by

PCL Clinical Laboratory - Core

Performed

Daily

Methodology

Nitroprusside reaction (Acetest).

Reported

Same day

Synonyms

  • LAB44
  • KETONE,S
  • ACETEST

Reference Interval

NEGATIVE

Performed by

PCL Clinical Laboratory - Core

CPT Codes

82009

Collection

LAB44

KETONE,S

 

Collect

One 4.5 mL Red top or Gold top tube with gel separator (SST).

Pediatric Collection

0.5 mL serum.

Unacceptable Conditions

Sample not properly identified; incorrect container; insufficient sample volume.

Storage/Transport Temperature

Internal: Deliver to lab immediately.
Offsite: Allow to clot for 20 minutes before centrifugation. Centrifuge within two hours of collection. Send at 2-8 degrees C.

Stability (from collection to initiation)

Ambient: 4 hours; Refrigerated: 48 hours; Frozen: Unacceptable.

Remarks

This is a semiquantitative method using acetest tablets to detect the presence of ketone bodies, acetoacetic acid, and acetone.  Does not detect betahydroxybutyric acid and is not specific for any one ketone.

Performed by

PCL Clinical Laboratory - Core

Ordering

Performed

Daily

Methodology

Nitroprusside reaction (Acetest).

Reported

Same day

Synonyms

  • LAB44
  • KETONE,S
  • ACETEST
Result Interpretation

Reference Interval

NEGATIVE

Performed by

PCL Clinical Laboratory - Core

Administrative

CPT Codes

82009

KOH PREP, SKIN

LAB3444

 

Collect

Skin scrapings from leading edge of lesion, placed in a sterile container.

Unacceptable Conditions

Sample not properly identified; incorrect container; sample in fixative; source/site not specified.

Storage/Transport Temperature

Internal: Deliver to lab immediately at ambient temperature.

Offsite: Deliver to lab immediately at ambient temperature.

Performed by

PCL Clinical Laboratory - Microbiology

Performed

Daily

Methodology

Microscopy

Reported

Same day

Synonyms

  • LAB3444

Interpretive Data

Positive or negative for mycotic elements.

Performed by

PCL Clinical Laboratory - Microbiology

CPT Codes

87220

Collection

LAB3444

 

Collect

Skin scrapings from leading edge of lesion, placed in a sterile container.

Unacceptable Conditions

Sample not properly identified; incorrect container; sample in fixative; source/site not specified.

Storage/Transport Temperature

Internal: Deliver to lab immediately at ambient temperature.

Offsite: Deliver to lab immediately at ambient temperature.

Performed by

PCL Clinical Laboratory - Microbiology

Ordering

Performed

Daily

Methodology

Microscopy

Reported

Same day

Synonyms

  • LAB3444
Result Interpretation

Interpretive Data

Positive or negative for mycotic elements.

Performed by

PCL Clinical Laboratory - Microbiology

Administrative

CPT Codes

87220