IMIPRAMINE + DESIPRAMINE

LAB3041

 

Collect

Plain red. Also acceptable: Lavender (K2 or K3EDTA) or pink (K2 EDTA).

Patient Preparation

Timing of specimen collection: Pre-dose (trough) draw - At steady state concentration.

Specimen Preparation

Separate serum or plasma from cells within 2 hours of collection. Transfer 1 mL serum or plasma to an ARUP Standard Transport Tube. (Min: 0.5 mL)

Unacceptable Conditions

Whole blood. Gel separator tubes, light blue (citrate), or yellow (SPS or ACD solution).

Storage/Transport Temperature

Refrigerated.

Stability (from collection to initiation)

After separation from cells: Ambient: 5 days; Refrigerated: 2 weeks; Frozen: 6 months

Notes

Report includes individual values for imipramine, desipramine, and total.

Performed

Mon, Wed, Fri

Methodology

Quantitative Liquid Chromatography-Tandem Mass Spectrometry

Reported

1-5 days

Synonyms

  • Desipramine/Imipramine
  • Tofranil
  • Presamine
  • Imavate
  • Imipramine/Desipramine Fractionation
  • LAB3041
  • DESIP/IMIP
  • IMIPRAMINE

Ordering Recommendations

Optimize drug therapy and monitor patient adherence.

Reference Interval

Effective February 19, 2013
Therapeutic RangeTotal (imipramine and desipramine): 150-300 ng/mL
Toxic LevelGreater than 500 ng/mL

Interpretive Data

Toxic concentrations may cause anticholinergic effects, drowsiness and cardiac abnormalities.

CPT Codes

80335 (Alt code: G0480)
Collection

LAB3041

 

Collect

Plain red. Also acceptable: Lavender (K2 or K3EDTA) or pink (K2 EDTA).

Patient Preparation

Timing of specimen collection: Pre-dose (trough) draw - At steady state concentration.

Specimen Preparation

Separate serum or plasma from cells within 2 hours of collection. Transfer 1 mL serum or plasma to an ARUP Standard Transport Tube. (Min: 0.5 mL)

Unacceptable Conditions

Whole blood. Gel separator tubes, light blue (citrate), or yellow (SPS or ACD solution).

Storage/Transport Temperature

Refrigerated.

Stability (from collection to initiation)

After separation from cells: Ambient: 5 days; Refrigerated: 2 weeks; Frozen: 6 months

Notes

Report includes individual values for imipramine, desipramine, and total.
Ordering

Performed

Mon, Wed, Fri

Methodology

Quantitative Liquid Chromatography-Tandem Mass Spectrometry

Reported

1-5 days

Synonyms

  • Desipramine/Imipramine
  • Tofranil
  • Presamine
  • Imavate
  • Imipramine/Desipramine Fractionation
  • LAB3041
  • DESIP/IMIP
  • IMIPRAMINE

Ordering Recommendations

Optimize drug therapy and monitor patient adherence.
Result Interpretation

Reference Interval

Effective February 19, 2013
Therapeutic RangeTotal (imipramine and desipramine): 150-300 ng/mL
Toxic LevelGreater than 500 ng/mL

Interpretive Data

Toxic concentrations may cause anticholinergic effects, drowsiness and cardiac abnormalities.

Administrative

CPT Codes

80335 (Alt code: G0480)

IMMUNOGLOBULIN A

LAB73

IGA

Collect

One 4.5 mL, GOLD top tube with gel separator (SST), serum. 

Pediatric Collection

1.5 mL blood.

Unacceptable Conditions

Sample not properly identified; incorrect container; insufficient sample volume.

Storage/Transport Temperature

Internal: Deliver to lab immediately.
Offsite: Centrifuge within 30 minutes of collection. Send at 2-8 degrees C.

Stability (from collection to initiation)

Ambient: Unacceptable; Refrigerated: 8 days; Frozen (-20 degrees C): 1 year.

Performed by

PCL Clinical Laboratory - Core

Performed

Daily

Methodology

Immunoturbidimetric

Reported

Daily

Synonyms

  • LAB73
  • IGA

Reference Interval

Effective 05/20/2014:

66 - 433 mg/dL

Adult reference range. Children often have values below this range.

 

Before 05/20/2014:

66-436 mg/dL

Performed by

PCL Clinical Laboratory - Core

CPT Codes

82784

Collection

LAB73

IGA

Collect

One 4.5 mL, GOLD top tube with gel separator (SST), serum. 

Pediatric Collection

1.5 mL blood.

Unacceptable Conditions

Sample not properly identified; incorrect container; insufficient sample volume.

Storage/Transport Temperature

Internal: Deliver to lab immediately.
Offsite: Centrifuge within 30 minutes of collection. Send at 2-8 degrees C.

Stability (from collection to initiation)

Ambient: Unacceptable; Refrigerated: 8 days; Frozen (-20 degrees C): 1 year.

Performed by

PCL Clinical Laboratory - Core

Ordering

Performed

Daily

Methodology

Immunoturbidimetric

Reported

Daily

Synonyms

  • LAB73
  • IGA
Result Interpretation

Reference Interval

Effective 05/20/2014:

66 - 433 mg/dL

Adult reference range. Children often have values below this range.

 

Before 05/20/2014:

66-436 mg/dL

Performed by

PCL Clinical Laboratory - Core

Administrative

CPT Codes

82784

IMMUNOGLOBULIN D

LAB3161

Collect

Serum separator tube.

Specimen Preparation

Separate serum from cells ASAP or within 2 hours of collection. Transfer 1 mL serum to an ARUP Standard Transport Tube. (Min: 0.5 mL)

Unacceptable Conditions

Contaminated, hemolyzed, or severely lipemic specimens.

Storage/Transport Temperature

Refrigerated.

Stability (from collection to initiation)

After separation from cells: Ambient: 8 hours; Refrigerated: 48 hours; Frozen: 1 month

Performed

Mon, Wed, Fri

Methodology

Quantitative Nephelometry

Reported

1-4 days

Synonyms

  • IgD, Serum
  • LAB3161
  • IGD

Ordering Recommendations

Aids in diagnosis of immunoglobulin disorders.

Reference Interval

Less than or equal to 15.3 mg/dL

Interpretive Data

IgD is one of the five classes of immunoglobulin.  IgD is mainly found on the surface of B-cells and may help regulate B-cell function. IgD likely serves as an early B-cell antigen receptor, however, the function of the circulating IgD is largely unknown.

CPT Codes

82784
Collection

LAB3161

Collect

Serum separator tube.

Specimen Preparation

Separate serum from cells ASAP or within 2 hours of collection. Transfer 1 mL serum to an ARUP Standard Transport Tube. (Min: 0.5 mL)

Unacceptable Conditions

Contaminated, hemolyzed, or severely lipemic specimens.

Storage/Transport Temperature

Refrigerated.

Stability (from collection to initiation)

After separation from cells: Ambient: 8 hours; Refrigerated: 48 hours; Frozen: 1 month
Ordering

Performed

Mon, Wed, Fri

Methodology

Quantitative Nephelometry

Reported

1-4 days

Synonyms

  • IgD, Serum
  • LAB3161
  • IGD

Ordering Recommendations

Aids in diagnosis of immunoglobulin disorders.
Result Interpretation

Reference Interval

Less than or equal to 15.3 mg/dL

Interpretive Data

IgD is one of the five classes of immunoglobulin.  IgD is mainly found on the surface of B-cells and may help regulate B-cell function. IgD likely serves as an early B-cell antigen receptor, however, the function of the circulating IgD is largely unknown.

Administrative

CPT Codes

82784

IMMUNOGLOBULIN E

LAB74

 

Collect

Serum separator tube or plasma separator tube. Also acceptable: Green (sodium or lithium heparin), lavender (EDTA), or pink (K2EDTA).

Specimen Preparation

Separate serum or plasma from cells ASAP or within 2 hours of collection. Transfer 1 mL serum or plasma to an ARUP Standard Transport Tube. (Min: 0.3 mL)

Storage/Transport Temperature

Refrigerated.

Stability (from collection to initiation)

After separation from cells: Ambient: 48 hours; Refrigerated: 2 weeks; Frozen: 1 year

Performed

Sun-Sat

Methodology

Quantitative ImmunoCAP® Fluorescent Enzyme Immunoassay

Reported

1-2 days

Synonyms

  • IgE, Serum
  • LAB74
  • IGE

Reference Interval

Effective November 17, 2014
Age
Reference Interval
0-5 months13 kU/L or less
6-12 months34 kU/L or less
1-2 years97 kU/L or less
3 years199 kU/L or less
4-6 years307 kU/L or less
7-8 years403 kU/L or less
9-12 years696 kU/L or less
13-15 years629 kU/L or less
16-17 years537 kU/L or less
18 years and older214 kU/L or less

CPT Codes

82785
Collection

LAB74

 

Collect

Serum separator tube or plasma separator tube. Also acceptable: Green (sodium or lithium heparin), lavender (EDTA), or pink (K2EDTA).

Specimen Preparation

Separate serum or plasma from cells ASAP or within 2 hours of collection. Transfer 1 mL serum or plasma to an ARUP Standard Transport Tube. (Min: 0.3 mL)

Storage/Transport Temperature

Refrigerated.

Stability (from collection to initiation)

After separation from cells: Ambient: 48 hours; Refrigerated: 2 weeks; Frozen: 1 year
Ordering

Performed

Sun-Sat

Methodology

Quantitative ImmunoCAP® Fluorescent Enzyme Immunoassay

Reported

1-2 days

Synonyms

  • IgE, Serum
  • LAB74
  • IGE
Result Interpretation

Reference Interval

Effective November 17, 2014
Age
Reference Interval
0-5 months13 kU/L or less
6-12 months34 kU/L or less
1-2 years97 kU/L or less
3 years199 kU/L or less
4-6 years307 kU/L or less
7-8 years403 kU/L or less
9-12 years696 kU/L or less
13-15 years629 kU/L or less
16-17 years537 kU/L or less
18 years and older214 kU/L or less

Administrative

CPT Codes

82785

IMMUNOGLOBULIN G

LAB71

IGG

 

Collect

One 4.5 mL GOLD top tube with gel separator (SST), serum.

Pediatric Collection

1.5 mL serum.

Unacceptable Conditions

Sample not properly identified; incorrect container; insufficient sample volume.

Storage/Transport Temperature

Internal: Deliver to lab immediately.
Offsite: Centrifuge within 30 minutes of collection. Send at 2-8 degrees C.

Stability (from collection to initiation)

Ambient: Unacceptable; Refrigerated: 1 week; Frozen (-20 degrees C): Greater than 1 week.

Performed by

PCL Clinical Laboratory - Core

Performed

Daily

Methodology

Immunoturbidimetric

Reported

Daily

Synonyms

  • LAB71
  • IGG

Reference Interval

Effective 05/20/2014:

635 - 1741 mg/dL

Adult reference range. Infants often have values below this range.

 

Before 05/20/2014:

Sex From Age To Age Normal Low Normal High Units
M/F 0M 5M 250 700 mg/dL
M/F 5M 11M 220 900 mg/dL
M/F 11M 1 290 1070 mg/dL
M/F 1 2 340 1200 mg/dL
M/F 2 4 420 1200 mg/dL
M/F 4 6 460 1240 mg/dL
M/F 6 9 650 1600 mg/dL
M/F 9 11 650 1600 mg/dL
M/F 11 150 700 1643 mg/dL

Performed by

PCL Clinical Laboratory - Core

CPT Codes

82784

Collection

LAB71

IGG

 

Collect

One 4.5 mL GOLD top tube with gel separator (SST), serum.

Pediatric Collection

1.5 mL serum.

Unacceptable Conditions

Sample not properly identified; incorrect container; insufficient sample volume.

Storage/Transport Temperature

Internal: Deliver to lab immediately.
Offsite: Centrifuge within 30 minutes of collection. Send at 2-8 degrees C.

Stability (from collection to initiation)

Ambient: Unacceptable; Refrigerated: 1 week; Frozen (-20 degrees C): Greater than 1 week.

Performed by

PCL Clinical Laboratory - Core

Ordering

Performed

Daily

Methodology

Immunoturbidimetric

Reported

Daily

Synonyms

  • LAB71
  • IGG
Result Interpretation

Reference Interval

Effective 05/20/2014:

635 - 1741 mg/dL

Adult reference range. Infants often have values below this range.

 

Before 05/20/2014:

Sex From Age To Age Normal Low Normal High Units
M/F 0M 5M 250 700 mg/dL
M/F 5M 11M 220 900 mg/dL
M/F 11M 1 290 1070 mg/dL
M/F 1 2 340 1200 mg/dL
M/F 2 4 420 1200 mg/dL
M/F 4 6 460 1240 mg/dL
M/F 6 9 650 1600 mg/dL
M/F 9 11 650 1600 mg/dL
M/F 11 150 700 1643 mg/dL

Performed by

PCL Clinical Laboratory - Core

Administrative

CPT Codes

82784

IMMUNOGLOBULIN M

LAB72

IGM

 

Collect

One 4.5 mL Gold top tube with gel separator (SST), serum.

Pediatric Collection

1.5 mL plasma.

Unacceptable Conditions

Sample not properly identified; incorrect container; insufficient sample volume.

Storage/Transport Temperature

Internal: Deliver to lab immediately.
Offsite: Centrifuge within 30 minutes of collection. Send at 2-8 degrees C.

Stability (from collection to initiation)

Ambient: Unacceptable; Refrigerated: 8 days; Frozen (-20 degrees C): 1 year.

Performed by

PCL Clinical Laboratory - Core

Performed

Daily

Methodology

Immunoturbidimetric

Reported

Daily

Synonyms

  • LAB72
  • IGM

Reference Interval

43-279 mg/dL

Adult reference range. Infants often have values below this range.

Performed by

PCL Clinical Laboratory - Core

CPT Codes

82784

Collection

LAB72

IGM

 

Collect

One 4.5 mL Gold top tube with gel separator (SST), serum.

Pediatric Collection

1.5 mL plasma.

Unacceptable Conditions

Sample not properly identified; incorrect container; insufficient sample volume.

Storage/Transport Temperature

Internal: Deliver to lab immediately.
Offsite: Centrifuge within 30 minutes of collection. Send at 2-8 degrees C.

Stability (from collection to initiation)

Ambient: Unacceptable; Refrigerated: 8 days; Frozen (-20 degrees C): 1 year.

Performed by

PCL Clinical Laboratory - Core

Ordering

Performed

Daily

Methodology

Immunoturbidimetric

Reported

Daily

Synonyms

  • LAB72
  • IGM
Result Interpretation

Reference Interval

43-279 mg/dL

Adult reference range. Infants often have values below this range.

Performed by

PCL Clinical Laboratory - Core

Administrative

CPT Codes

82784

IMMUNOGLOBULIN PANEL

LAB3020

IG GAM

Collect

One 4.5 mL Gold top tube with gel separator (SST).

Pediatric Collection

Minimum volume: 0.5 mL plasma.

Unacceptable Conditions

Sample not properly identified; incorrect container; insufficient sample volume.

Storage/Transport Temperature

Internal: Deliver to lab immediately.
Offsite: Centrifuge within 30 minutes of collection. Send at 2-8 degrees C.

Stability (from collection to initiation)

Refrigerated: 3 days; Frozen (-20 degrees C): 1 year.

Remarks

Includes IgG, IgA and IgM.

Performed by

PCL Clinical Laboratory - Core

Performed

Daily

Methodology

Immunonephelometry

Reported

Same day

Synonyms

  • LAB3020
  • IG GAM

Reference Interval

Effective 05/20/2014:

Component Normal Low Normal High Units
IMMUNOGLOBULIN A 66 433 mg/dL
IMMUNOGLOBULIN G 635 1741 mg/dL
IMMUNOGLOBULIN M 43 279 mg/dL

 

Before 05/20/2014:

Component Sex From Age To Age Normal Low Normal High Units
IMMUNOGLOBULIN A M/F 16 150 66 436 mg/dL
IMMUNOGLOBULIN G M/F 1M 5M 250 700 mg/dL
  M/F 5M 11M 220 900 mg/dL
  M/F 11M 1 290 1070 mg/dL
  M/F 1 2 340 1200 mg/dL
  M/F 2 4 420 1200 mg/dL
  M/F 4 6 460 1240 mg/dL
  M/F 6 9 650 1600 mg/dL
  M/F 9 11 650 1600 mg/dL
  M/F 11 150 791 1643 mg/dL
IMMUNOGLOBULIN M M/F 18 150 43 279 mg/dL

Interpretive Data

Effective 05/20/2014:

IgA: Adult reference range.  Children often have values below this range.

IgG, IgM: Adult reference range.  Infants often have values below this range.

Performed by

PCL Clinical Laboratory - Core

CPT Codes

82784 (3)

Collection

LAB3020

IG GAM

Collect

One 4.5 mL Gold top tube with gel separator (SST).

Pediatric Collection

Minimum volume: 0.5 mL plasma.

Unacceptable Conditions

Sample not properly identified; incorrect container; insufficient sample volume.

Storage/Transport Temperature

Internal: Deliver to lab immediately.
Offsite: Centrifuge within 30 minutes of collection. Send at 2-8 degrees C.

Stability (from collection to initiation)

Refrigerated: 3 days; Frozen (-20 degrees C): 1 year.

Remarks

Includes IgG, IgA and IgM.

Performed by

PCL Clinical Laboratory - Core

Ordering

Performed

Daily

Methodology

Immunonephelometry

Reported

Same day

Synonyms

  • LAB3020
  • IG GAM
Result Interpretation

Reference Interval

Effective 05/20/2014:

Component Normal Low Normal High Units
IMMUNOGLOBULIN A 66 433 mg/dL
IMMUNOGLOBULIN G 635 1741 mg/dL
IMMUNOGLOBULIN M 43 279 mg/dL

 

Before 05/20/2014:

Component Sex From Age To Age Normal Low Normal High Units
IMMUNOGLOBULIN A M/F 16 150 66 436 mg/dL
IMMUNOGLOBULIN G M/F 1M 5M 250 700 mg/dL
  M/F 5M 11M 220 900 mg/dL
  M/F 11M 1 290 1070 mg/dL
  M/F 1 2 340 1200 mg/dL
  M/F 2 4 420 1200 mg/dL
  M/F 4 6 460 1240 mg/dL
  M/F 6 9 650 1600 mg/dL
  M/F 9 11 650 1600 mg/dL
  M/F 11 150 791 1643 mg/dL
IMMUNOGLOBULIN M M/F 18 150 43 279 mg/dL

Interpretive Data

Effective 05/20/2014:

IgA: Adult reference range.  Children often have values below this range.

IgG, IgM: Adult reference range.  Infants often have values below this range.

Performed by

PCL Clinical Laboratory - Core

Administrative

CPT Codes

82784 (3)

IMMUNOPHENOTYPING- LEUKEMIA AND LYMPHOMA

LAB3358

Collect

Always include a flow cytometry Lab Requisition and include patient name, ICD9 code, and working diagnosis/neoplastic condition.

Peripheral blood: One 6.0 mL, green top no gel (sodium heparin plasma)

Bone marrow: At least 1.0 mL of aspirate in green top no gel (sodium heparin plasma).

FNA, tissue: Place sample in 6 mL of thawed transport media.

Body fluids: At least 10 mL of fluid in sterile tube, container or syringe.

Remove needle prior to transportation when submitting sample in a syringe

Unacceptable Conditions

Frozen samples; sample submitted in fixative solutions; sample not properly identified; insufficient sample volume.

Storage/Transport Temperature

Internal: Deliver to lab immediately at ambient temperature
Offsite: Do not centrifuge. Deliver at ambient temperature within 24 hours of collection.

Stability (from collection to initiation)

Peripheral blood and bone marrow: Ambient, 24 hours; Refrigerated, 24 hours, Frozen, unacceptable

Tissue and other fluids: Ambient: 4 hours, Refrigerated: 24 hours, Frozen, unacceptable.

Performed by

PCL Clinical Laboratory - Flow Cytometry

Synonyms

  • LAB3358

Performed by

PCL Clinical Laboratory - Flow Cytometry

CPT Codes

88184 first marker; 88185 varies depending on diagnosis, call lab 720-848-4401

Collection

LAB3358

Collect

Always include a flow cytometry Lab Requisition and include patient name, ICD9 code, and working diagnosis/neoplastic condition.

Peripheral blood: One 6.0 mL, green top no gel (sodium heparin plasma)

Bone marrow: At least 1.0 mL of aspirate in green top no gel (sodium heparin plasma).

FNA, tissue: Place sample in 6 mL of thawed transport media.

Body fluids: At least 10 mL of fluid in sterile tube, container or syringe.

Remove needle prior to transportation when submitting sample in a syringe

Unacceptable Conditions

Frozen samples; sample submitted in fixative solutions; sample not properly identified; insufficient sample volume.

Storage/Transport Temperature

Internal: Deliver to lab immediately at ambient temperature
Offsite: Do not centrifuge. Deliver at ambient temperature within 24 hours of collection.

Stability (from collection to initiation)

Peripheral blood and bone marrow: Ambient, 24 hours; Refrigerated, 24 hours, Frozen, unacceptable

Tissue and other fluids: Ambient: 4 hours, Refrigerated: 24 hours, Frozen, unacceptable.

Performed by

PCL Clinical Laboratory - Flow Cytometry

Ordering

Synonyms

  • LAB3358
Result Interpretation

Performed by

PCL Clinical Laboratory - Flow Cytometry

Administrative

CPT Codes

88184 first marker; 88185 varies depending on diagnosis, call lab 720-848-4401

INDIA INK PREP

Remarks

This test is no longer performed. The laboratory recommends that you order a latex agglutination (CRYPTO AG) if Cryptococcal Meningitis is suspected based on clinical grounds and abnormal CSF.
Collection

Remarks

This test is no longer performed. The laboratory recommends that you order a latex agglutination (CRYPTO AG) if Cryptococcal Meningitis is suspected based on clinical grounds and abnormal CSF.
Ordering
Result Interpretation
Administrative

INDIRECT AHG

Collect

Cord blood or venous draw from newborn in one 6 mL Pink top tube (EDTA).

Also acceptable: Cord blood or venous draw from newborn in one 4 mL Purple top tube (EDTA).

See labeling requirements in Remarks.

Pediatric Collection

3 mL blood.

Unacceptable Conditions

Sample not properly identified; incorrect container; insufficient sample volume; gross hemolysis.

Storage/Transport Temperature

Internal: Deliver to lab immediately.
Offsite: Send at ambient temperature within 8 hours, or at 2-8 degrees C within 24 hours.

Stability (from collection to initiation)

Ambient: 8 hours; Refrigerated: 72 hours; Frozen: Unacceptable.

Remarks

Cord blood is labeled with the mother's label including complete first, last name, and medical record number. Place in a plastic bag. Label the bag with newborn's label including complete first name, last name, medical record number, date drawn, and phlebotomist's initials.

Additional specimen may be requested if antibody identification is indicated.

Performed by

PCL Clinical Laboratory - Transfusion Service (Blood Bank)

Performed

Daily

Methodology

Hemagglutination (HA).

Reported

Same day

Synonyms

  • LAB1282

Performed by

PCL Clinical Laboratory - Transfusion Service (Blood Bank)

CPT Codes

86885
Collection

Collect

Cord blood or venous draw from newborn in one 6 mL Pink top tube (EDTA).

Also acceptable: Cord blood or venous draw from newborn in one 4 mL Purple top tube (EDTA).

See labeling requirements in Remarks.

Pediatric Collection

3 mL blood.

Unacceptable Conditions

Sample not properly identified; incorrect container; insufficient sample volume; gross hemolysis.

Storage/Transport Temperature

Internal: Deliver to lab immediately.
Offsite: Send at ambient temperature within 8 hours, or at 2-8 degrees C within 24 hours.

Stability (from collection to initiation)

Ambient: 8 hours; Refrigerated: 72 hours; Frozen: Unacceptable.

Remarks

Cord blood is labeled with the mother's label including complete first, last name, and medical record number. Place in a plastic bag. Label the bag with newborn's label including complete first name, last name, medical record number, date drawn, and phlebotomist's initials.

Additional specimen may be requested if antibody identification is indicated.

Performed by

PCL Clinical Laboratory - Transfusion Service (Blood Bank)
Ordering

Performed

Daily

Methodology

Hemagglutination (HA).

Reported

Same day

Synonyms

  • LAB1282
Result Interpretation

Performed by

PCL Clinical Laboratory - Transfusion Service (Blood Bank)
Administrative

CPT Codes

86885

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