LAB3041
Collect
Plain red. Also acceptable: Lavender (K2 or K3EDTA) or pink (K2 EDTA).
Patient Preparation
Timing of specimen collection: Pre-dose (trough) draw - At steady state concentration.
Specimen Preparation
Separate serum or plasma from cells within 2 hours of collection. Transfer 1 mL serum or plasma to an ARUP Standard Transport Tube. (Min: 0.5 mL)
Unacceptable Conditions
Whole blood. Gel separator tubes, light blue (citrate), or yellow (SPS or ACD solution).
Storage/Transport Temperature
Refrigerated.
Stability (from collection to initiation)
After separation from cells: Ambient: 5 days; Refrigerated: 2 weeks; Frozen: 6 months
Notes
Report includes individual values for imipramine, desipramine, and total.
Performed
Mon, Wed, Fri
Methodology
Quantitative Liquid Chromatography-Tandem Mass Spectrometry
Reported
1-5 days
Synonyms
- Desipramine/Imipramine
- Tofranil
- Presamine
- Imavate
- Imipramine/Desipramine Fractionation
- LAB3041
- DESIP/IMIP
- IMIPRAMINE
Ordering Recommendations
Optimize drug therapy and monitor patient adherence.
Reference Interval
Effective February 19, 2013
Therapeutic Range | Total (imipramine and desipramine): 150-300 ng/mL |
Toxic Level | Greater than 500 ng/mL |
Interpretive Data
Toxic concentrations may cause anticholinergic effects, drowsiness and cardiac abnormalities.
CPT Codes
80335 (Alt code: G0480)
Collection |
LAB3041
Collect
Plain red. Also acceptable: Lavender (K2 or K3EDTA) or pink (K2 EDTA).
Patient Preparation
Timing of specimen collection: Pre-dose (trough) draw - At steady state concentration.
Specimen Preparation
Separate serum or plasma from cells within 2 hours of collection. Transfer 1 mL serum or plasma to an ARUP Standard Transport Tube. (Min: 0.5 mL)
Unacceptable Conditions
Whole blood. Gel separator tubes, light blue (citrate), or yellow (SPS or ACD solution).
Storage/Transport Temperature
Refrigerated.
Stability (from collection to initiation)
After separation from cells: Ambient: 5 days; Refrigerated: 2 weeks; Frozen: 6 months
Notes
Report includes individual values for imipramine, desipramine, and total.
Ordering |
Performed
Mon, Wed, Fri
Methodology
Quantitative Liquid Chromatography-Tandem Mass Spectrometry
Reported
1-5 days
Synonyms
- Desipramine/Imipramine
- Tofranil
- Presamine
- Imavate
- Imipramine/Desipramine Fractionation
- LAB3041
- DESIP/IMIP
- IMIPRAMINE
Ordering Recommendations
Optimize drug therapy and monitor patient adherence.
Result Interpretation |
Reference Interval
Effective February 19, 2013
Therapeutic Range | Total (imipramine and desipramine): 150-300 ng/mL |
Toxic Level | Greater than 500 ng/mL |
Interpretive Data
Toxic concentrations may cause anticholinergic effects, drowsiness and cardiac abnormalities.
Administrative |
CPT Codes
80335 (Alt code: G0480)