Tests Catalogs

Epstein-Barr Virus by PCR, whole blood

LAB3247

Collect

One 6.0 mL pink top (EDTA) filled to at least 80% capacity.

Specimen source is required to be included on requisition.

Pediatric Collection

At least 0.5 mL of whole blood collected in a 1.0 mL pink top microtainer (EDTA) or other blood tube with EDTA anticoagulant.

Unacceptable Conditions

Contaminated specimen; clotted sample; tubes not filed to 80-100% capacity; improper storage conditions; samples stored in fixative; sample not properly identified; insufficient sample volume.

Storage/Transport Temperature

Internal: Deliver to lab immediately at ambient temperature.
Offsite: Do not centrifuge. If delivered within 72 hours, send at 2-8 degrees C. If delivery is not expected within 72 hours, freeze at -70 degrees C and ship on dry ice.

 

Stability (from collection to initiation)

Ambient, 12 hours; Refrigerated, 72 hours; Frozen (-70 degrees C), 6 months.

Remarks

Quantitative results will be given.

Performed by

PCL Clinical Laboratory - Molecular Diagnostics

Performed

Mon-Fri.

Methodology

DNA amplification by polymerase chain reaction (PCR) using a EBV-specific DNA probe detected by real-time PCR.

Reported

24-48 hours

Synonyms

  • -743 EBV PCR blood
  • LAB3247

Interpretive Data

TND - Target Not Detected (negative)

POS<1000 = Positive. Virus detected below 1000 copies/mL

1001-1,000,000 copies/mL = Quantitative ranges

>1,000,000 copies/mL = Greater than maximum quantitative range.

Performed by

PCL Clinical Laboratory - Molecular Diagnostics

CPT Codes

87799

Collection

LAB3247

Collect

One 6.0 mL pink top (EDTA) filled to at least 80% capacity.

Specimen source is required to be included on requisition.

Pediatric Collection

At least 0.5 mL of whole blood collected in a 1.0 mL pink top microtainer (EDTA) or other blood tube with EDTA anticoagulant.

Unacceptable Conditions

Contaminated specimen; clotted sample; tubes not filed to 80-100% capacity; improper storage conditions; samples stored in fixative; sample not properly identified; insufficient sample volume.

Storage/Transport Temperature

Internal: Deliver to lab immediately at ambient temperature.
Offsite: Do not centrifuge. If delivered within 72 hours, send at 2-8 degrees C. If delivery is not expected within 72 hours, freeze at -70 degrees C and ship on dry ice.

 

Stability (from collection to initiation)

Ambient, 12 hours; Refrigerated, 72 hours; Frozen (-70 degrees C), 6 months.

Remarks

Quantitative results will be given.

Performed by

PCL Clinical Laboratory - Molecular Diagnostics

Ordering

Performed

Mon-Fri.

Methodology

DNA amplification by polymerase chain reaction (PCR) using a EBV-specific DNA probe detected by real-time PCR.

Reported

24-48 hours

Synonyms

  • -743 EBV PCR blood
  • LAB3247
Result Interpretation

Interpretive Data

TND - Target Not Detected (negative)

POS<1000 = Positive. Virus detected below 1000 copies/mL

1001-1,000,000 copies/mL = Quantitative ranges

>1,000,000 copies/mL = Greater than maximum quantitative range.

Performed by

PCL Clinical Laboratory - Molecular Diagnostics

Administrative

CPT Codes

87799

Epstein-Barr Virus Quant PCR, samples other than blood

LAB3248

Collect

If submitting a Pink Top tube (EDTA) whole blood, refer to test code EBVPCRBLD.

All sample types submitted in a sterile container, including serum from red top tube.

Specimen source must be included on requisition. 

Pediatric Collection

At least 0.5 mL of sample in a sterile container.

Unacceptable Conditions

Whole blood and plasma samples; non sterile or leaking containers; sample not properly identified; insufficient sample volume; contaminated specimen; clotted sample; samples containing fixatives.

Storage/Transport Temperature

Internal: Deliver to lab immediately at ambient temperature.
Offsite: Send at 2-8 degrees C if delivered within 72 hours. If delivery is not expected within 72 hours, freeze at -70 degrees C and ship on dry ice.

Stability (from collection to initiation)

Ambient, 12 hours; Refrigerated, 72 hours; Frozen (-70 degrees C), 6 months.

Remarks

Quantitative results will be given for all urine samples. Qualitative results will be given for tissues, stools, swabs, or diluted samples.

Performed by

PCL Clinical Laboratory - Molecular Diagnostics

Performed

Mon - Fri

Methodology

DNA amplification by polymerase chain reaction (PCR) using an EBV-specific DNA probe detected by real-time PCR.

Reported

24-48 hours

Synonyms

  • LAB3248

Interpretive Data

Qualitative testing:

TND = Target Not Detected (negative)

Positive = Virus Detected

Quantitative testing:

TND = Target Not Detected (negative)

POS<1000 = Positive. Virus detected below 1000 copies/mL

1001 - 1,000,000 copies/mL = Quantitative range

>1,000,000 copies/mL = Greater than maximum quantitative range

Performed by

PCL Clinical Laboratory - Molecular Diagnostics

CPT Codes

87799 (quantitative); 87798 (qualitative)

Collection

LAB3248

Collect

If submitting a Pink Top tube (EDTA) whole blood, refer to test code EBVPCRBLD.

All sample types submitted in a sterile container, including serum from red top tube.

Specimen source must be included on requisition. 

Pediatric Collection

At least 0.5 mL of sample in a sterile container.

Unacceptable Conditions

Whole blood and plasma samples; non sterile or leaking containers; sample not properly identified; insufficient sample volume; contaminated specimen; clotted sample; samples containing fixatives.

Storage/Transport Temperature

Internal: Deliver to lab immediately at ambient temperature.
Offsite: Send at 2-8 degrees C if delivered within 72 hours. If delivery is not expected within 72 hours, freeze at -70 degrees C and ship on dry ice.

Stability (from collection to initiation)

Ambient, 12 hours; Refrigerated, 72 hours; Frozen (-70 degrees C), 6 months.

Remarks

Quantitative results will be given for all urine samples. Qualitative results will be given for tissues, stools, swabs, or diluted samples.

Performed by

PCL Clinical Laboratory - Molecular Diagnostics

Ordering

Performed

Mon - Fri

Methodology

DNA amplification by polymerase chain reaction (PCR) using an EBV-specific DNA probe detected by real-time PCR.

Reported

24-48 hours

Synonyms

  • LAB3248
Result Interpretation

Interpretive Data

Qualitative testing:

TND = Target Not Detected (negative)

Positive = Virus Detected

Quantitative testing:

TND = Target Not Detected (negative)

POS<1000 = Positive. Virus detected below 1000 copies/mL

1001 - 1,000,000 copies/mL = Quantitative range

>1,000,000 copies/mL = Greater than maximum quantitative range

Performed by

PCL Clinical Laboratory - Molecular Diagnostics

Administrative

CPT Codes

87799 (quantitative); 87798 (qualitative)

ERYTHROCYTE PROPHYRINS [EP] WB

LAB1084

Collect

Royal blue (EDTA), lavender (EDTA), pink (K2EDTA), or Tan ( K2EDTA). Use royal blue tube when also testing for lead. 

Specimen Preparation

Protect from light during collection, storage, and shipment. Transfer 1 mL whole blood to an ARUP Amber Transport Tube. (Min: 0.5 mL)

Unacceptable Conditions

Specimens not collected in EDTA. Clotted specimens.

Storage/Transport Temperature

Refrigerated.

Stability (from collection to initiation)

Ambient: Unacceptable; Refrigerated: 2 weeks; Frozen: 1 month

Remarks

Specimen should be tested for lead FIRST to avoid potential contamination problems. Specimens not protected from light acceptable with a disclaimer.

Notes

Elevated EP results are seen in early and late iron deficiency, in the anemia of chronic disease, and in chronic lead poisoning (typically when blood lead is greater than 25 µg/dL).  Elevated protoporphyrin (as in erythropoietic protoporphyria) and zinc coproporphyrin (usually associated with childbirth) can increase the apparent EP signal. A more specific test for free protoporphyrin is Porphyrins, Serum Total (0080429).  Specimens which are hemolyzed, clotted, or improperly aliquoted may show false elevations.

Performed

Mon, Wed, Sat

Methodology

Fluorometry

Reported

1-4 days

Synonyms

  • FEP
  • Porphyrins, Whole Blood (FEP)
  • Protoporphyrin, Free Erythrocyte (FEP)
  • LAB1084
  • EP

Ordering Recommendations

Screen for erythropoietic protoporphyria (EPP) in patients with cutaneous photosensitivity.

Reference Interval

0-35 µg/dL

CPT Codes

84202
Collection

LAB1084

Collect

Royal blue (EDTA), lavender (EDTA), pink (K2EDTA), or Tan ( K2EDTA). Use royal blue tube when also testing for lead. 

Specimen Preparation

Protect from light during collection, storage, and shipment. Transfer 1 mL whole blood to an ARUP Amber Transport Tube. (Min: 0.5 mL)

Unacceptable Conditions

Specimens not collected in EDTA. Clotted specimens.

Storage/Transport Temperature

Refrigerated.

Stability (from collection to initiation)

Ambient: Unacceptable; Refrigerated: 2 weeks; Frozen: 1 month

Remarks

Specimen should be tested for lead FIRST to avoid potential contamination problems. Specimens not protected from light acceptable with a disclaimer.

Notes

Elevated EP results are seen in early and late iron deficiency, in the anemia of chronic disease, and in chronic lead poisoning (typically when blood lead is greater than 25 µg/dL).  Elevated protoporphyrin (as in erythropoietic protoporphyria) and zinc coproporphyrin (usually associated with childbirth) can increase the apparent EP signal. A more specific test for free protoporphyrin is Porphyrins, Serum Total (0080429).  Specimens which are hemolyzed, clotted, or improperly aliquoted may show false elevations.
Ordering

Performed

Mon, Wed, Sat

Methodology

Fluorometry

Reported

1-4 days

Synonyms

  • FEP
  • Porphyrins, Whole Blood (FEP)
  • Protoporphyrin, Free Erythrocyte (FEP)
  • LAB1084
  • EP

Ordering Recommendations

Screen for erythropoietic protoporphyria (EPP) in patients with cutaneous photosensitivity.
Result Interpretation

Reference Interval

0-35 µg/dL
Administrative

CPT Codes

84202

ERYTHROCYTE SEDIMENTATION RATE

LAB322

ESR

 

Collect

One 4 mL Purple top (EDTA whole blood).  Minimum volume 1.0 mL.

Pediatric Collection

Sent out to Children’s Hospital Colorado.

  • EDTA microtainers are acceptable pediatric specimens. Deliver to lab immediately. Specimens must be received in Children’s Hospital Laboratory within 6 hours of collection in purple top tube (K2 EDTA).
  • Optimal volume 1.0 mL
  • Minimum volume 0.4 mL

Unacceptable Conditions

Sample not properly identified; incorrect container; insufficient sample volume; clotted sample; frozen sample; centrifuged sample.
EDTA Microtainer tubes are not acceptable except for pediatric specimens, which are sent to Children's Hospital Colorado for testing.

Storage/Transport Temperature

Internal: Deliver to lab immediately.
Offsite: Do not centrifuge. Transport to laboratory at 2-8 degrees C.

Stability (from collection to initiation)

Ambient: 8 hours; Refrigerated: 24 hours; Frozen: Unacceptable.

Performed by

PCL Clinical Laboratory - Core

Children's Hospital Colorado for pediatric specimens only.

Performed

Daily

Methodology

Automated Erythrocyte Sedimentation Rate

Reported

Routine requests are reported within 8 hours.

Synonyms

  • LAB322
  • ESR
  • SED RATE

Reference Interval

Sex From Age To Age Normal Low Normal High Units
F 0 150 0 20 mm/Hr
M 0 150 0 10 mm/Hr

Performed by

PCL Clinical Laboratory - Core

Children's Hospital Colorado for pediatric specimens only.

CPT Codes

85652

Collection

LAB322

ESR

 

Collect

One 4 mL Purple top (EDTA whole blood).  Minimum volume 1.0 mL.

Pediatric Collection

Sent out to Children’s Hospital Colorado.

  • EDTA microtainers are acceptable pediatric specimens. Deliver to lab immediately. Specimens must be received in Children’s Hospital Laboratory within 6 hours of collection in purple top tube (K2 EDTA).
  • Optimal volume 1.0 mL
  • Minimum volume 0.4 mL

Unacceptable Conditions

Sample not properly identified; incorrect container; insufficient sample volume; clotted sample; frozen sample; centrifuged sample.
EDTA Microtainer tubes are not acceptable except for pediatric specimens, which are sent to Children's Hospital Colorado for testing.

Storage/Transport Temperature

Internal: Deliver to lab immediately.
Offsite: Do not centrifuge. Transport to laboratory at 2-8 degrees C.

Stability (from collection to initiation)

Ambient: 8 hours; Refrigerated: 24 hours; Frozen: Unacceptable.

Performed by

PCL Clinical Laboratory - Core

Children's Hospital Colorado for pediatric specimens only.

Ordering

Performed

Daily

Methodology

Automated Erythrocyte Sedimentation Rate

Reported

Routine requests are reported within 8 hours.

Synonyms

  • LAB322
  • ESR
  • SED RATE
Result Interpretation

Reference Interval

Sex From Age To Age Normal Low Normal High Units
F 0 150 0 20 mm/Hr
M 0 150 0 10 mm/Hr

Performed by

PCL Clinical Laboratory - Core

Children's Hospital Colorado for pediatric specimens only.

Administrative

CPT Codes

85652

ERYTHROPOIETIN

LAB873

Collect

Serum separator tube or plasma separator tube.

Specimen Preparation

Allow serum to clot completely at room temperature. Separate serum or plasma from cells ASAP or within 2 hours of collection. Transfer 1 mL serum or plasma to an ARUP Standard Transport Tube. (Min: 0.5 mL)

Unacceptable Conditions

Bone marrow aspirate. EDTA plasma. Hemolyzed specimens.

Storage/Transport Temperature

Refrigerated.

Stability (from collection to initiation)

After separation from cells: Ambient: 8 hours; Refrigerated: 1 week; Frozen: 2 months

Performed

Sun-Sat

Methodology

Quantitative Chemiluminescent Immunoassay

Reported

Within 24 hours

Ordering Recommendations

Initial screening test for evaluation of polycythemia. Determine eligibility for erythropoietin therapy in anemia due to chronic renal failure.

Reference Interval

Normal serum concentrations of erythropoietin for 95% of individuals with normal hematocrits range from 4-27 mU/mL. 

As the hematocrit is lowered by iron deficiency, aplastic or hemolytic anemia, the concentration of erythropoietin increases as shown in the graph below. In the absence of anemia, elevated concentrations are seen in renal tumors, as a manifestation of renal transplant rejection, and in secondary polycythemia. Low values may be observed in hemochromatosis.

Decreased erythropoietin concentrations with an elevated hematocrit are observed in patients with polycythemia rubra vera, and with a decreased hematocrit in patients with HIV infection who are receiving AZT. Patients on AZT who have anemia and erythropoietin concentrations of less than or equal to 500 mU/mL, may benefit from therapy with recombinant EPO (NEJM 322:1488-1493, 1990).

EXPECTED ERYTHROPOIETIN CONCENTRATIONS IN PATIENTS WITH UNCOMPLICATED ANEMIA

                    ERYTHROPOIETIN (mU/mL)

                100,000 -

       
                                      
                   10,000 -       .............
                                          .............
                                            .............
                                              .............
                     1,000 -                .............
                                                  .............
                                                    .............
                                                      .............
                        100 -                        .............
                                                          .............
                                                            .............
                          10 -                              .............
                                                                .............
                               ___________________________       
                                           10   20   30  40   50   60   70

                                               (HEMATOCRIT %)

(CONTRIBUTIONS TO NEPHROLOGY 1988:66:54-62)

CPT Codes

82668
Collection

LAB873

Collect

Serum separator tube or plasma separator tube.

Specimen Preparation

Allow serum to clot completely at room temperature. Separate serum or plasma from cells ASAP or within 2 hours of collection. Transfer 1 mL serum or plasma to an ARUP Standard Transport Tube. (Min: 0.5 mL)

Unacceptable Conditions

Bone marrow aspirate. EDTA plasma. Hemolyzed specimens.

Storage/Transport Temperature

Refrigerated.

Stability (from collection to initiation)

After separation from cells: Ambient: 8 hours; Refrigerated: 1 week; Frozen: 2 months
Ordering

Performed

Sun-Sat

Methodology

Quantitative Chemiluminescent Immunoassay

Reported

Within 24 hours

Ordering Recommendations

Initial screening test for evaluation of polycythemia. Determine eligibility for erythropoietin therapy in anemia due to chronic renal failure.
Result Interpretation

Reference Interval

Normal serum concentrations of erythropoietin for 95% of individuals with normal hematocrits range from 4-27 mU/mL. 

As the hematocrit is lowered by iron deficiency, aplastic or hemolytic anemia, the concentration of erythropoietin increases as shown in the graph below. In the absence of anemia, elevated concentrations are seen in renal tumors, as a manifestation of renal transplant rejection, and in secondary polycythemia. Low values may be observed in hemochromatosis.

Decreased erythropoietin concentrations with an elevated hematocrit are observed in patients with polycythemia rubra vera, and with a decreased hematocrit in patients with HIV infection who are receiving AZT. Patients on AZT who have anemia and erythropoietin concentrations of less than or equal to 500 mU/mL, may benefit from therapy with recombinant EPO (NEJM 322:1488-1493, 1990).

EXPECTED ERYTHROPOIETIN CONCENTRATIONS IN PATIENTS WITH UNCOMPLICATED ANEMIA

                    ERYTHROPOIETIN (mU/mL)

                100,000 -

       
                                      
                   10,000 -       .............
                                          .............
                                            .............
                                              .............
                     1,000 -                .............
                                                  .............
                                                    .............
                                                      .............
                        100 -                        .............
                                                          .............
                                                            .............
                          10 -                              .............
                                                                .............
                               ___________________________       
                                           10   20   30  40   50   60   70

                                               (HEMATOCRIT %)

(CONTRIBUTIONS TO NEPHROLOGY 1988:66:54-62)
Administrative

CPT Codes

82668

ESTRADIOL

LAB523

E2

Collect

One 4.5 mL Gold top with gel separator (SST), clot activator serum.

 

Pediatric Collection

Minimum volume: 1.5 mL

Unacceptable Conditions

Sample not properly identified; incorrect container; insufficient sample volume.

Storage/Transport Temperature

Internal: Deliver to lab immediately.
Offsite: Allow to clot for 30 minutes prior to centrifugation. Centrifuge within 2 hours of collection and tranport at 2-8 degrees C.

Stability (from collection to initiation)

After centrifugation:

Ambient, 8 hours; Refrigerated, 2 days; Frozen, Unacceptable.

Serum aliquot:

Ambient, 8 hours; Refrigerated, 2 days; Frozen (-20 degrees C), Unknown.

Performed by

PCL Clinical Laboratory - Core

Performed

Daily

Methodology

Chemiluminescent Immunoasay

Reported

Same day

Synonyms

  • LAB523

Interpretive Data

Males: <20-40 pg/mL

Menstruating Females (by day in cycle relative to LH peak):

Follicular Phase (-12 to -4 days) 20-144 pg/mL
Midcycle (-3 to +2 days) 64-357 pg/mL
Luteal Phase (+4 to +12 days) 56-214 pg/mL
Postmenopausal Females (untreated) <20-32 pg/mL

 

 

 

 

 

Performed by

PCL Clinical Laboratory - Core

CPT Codes

82670

Collection

LAB523

E2

Collect

One 4.5 mL Gold top with gel separator (SST), clot activator serum.

 

Pediatric Collection

Minimum volume: 1.5 mL

Unacceptable Conditions

Sample not properly identified; incorrect container; insufficient sample volume.

Storage/Transport Temperature

Internal: Deliver to lab immediately.
Offsite: Allow to clot for 30 minutes prior to centrifugation. Centrifuge within 2 hours of collection and tranport at 2-8 degrees C.

Stability (from collection to initiation)

After centrifugation:

Ambient, 8 hours; Refrigerated, 2 days; Frozen, Unacceptable.

Serum aliquot:

Ambient, 8 hours; Refrigerated, 2 days; Frozen (-20 degrees C), Unknown.

Performed by

PCL Clinical Laboratory - Core

Ordering

Performed

Daily

Methodology

Chemiluminescent Immunoasay

Reported

Same day

Synonyms

  • LAB523
Result Interpretation

Interpretive Data

Males: <20-40 pg/mL

Menstruating Females (by day in cycle relative to LH peak):

Follicular Phase (-12 to -4 days) 20-144 pg/mL
Midcycle (-3 to +2 days) 64-357 pg/mL
Luteal Phase (+4 to +12 days) 56-214 pg/mL
Postmenopausal Females (untreated) <20-32 pg/mL

 

 

 

 

 

Performed by

PCL Clinical Laboratory - Core

Administrative

CPT Codes

82670

ESTRIOL, SERUM

LAB3152

Collect

Serum separator tube.

Specimen Preparation

Transfer 1 mL serum to an ARUP Standard Transport Tube. (Min: 0.6 mL)

Unacceptable Conditions

Plasma.

Storage/Transport Temperature

Refrigerated.

Stability (from collection to initiation)

After separation from cells: Ambient: 24 hours; Refrigerated: 1 week; Frozen: 1 month (avoid repeated freeze/thaw cycles)

Remarks

Patient gestational age required.

Performed

Sun-Sat

Methodology

Quantitative Chemiluminescent Immunoassay

Reported

1-2 days

Synonyms

  • E3 with Estriol
  • LAB3152
  • EST

Ordering Recommendations

Screening test for fetal aneuploidy in conjunction with other biomarkers and ultrasonography. Indicator of fetal well-being and placental function.

Reference Interval

Effective November 19, 2012
Based on gestational age:
25 weeks1.9 - 6.7 ng/mL
26 weeks2.0 - 7.3 ng/mL
27 - 29 weeks2.1 - 9.1 ng/mL
30 - 31 weeks2.4 - 10.6 ng/mL
32 - 37 weeks2.6 - 16.7 ng/mL
Nonpregnant FemaleLess than 0.08 ng/mL
MaleLess than 0.16 ng/mL

CPT Codes

82677
Collection

LAB3152

Collect

Serum separator tube.

Specimen Preparation

Transfer 1 mL serum to an ARUP Standard Transport Tube. (Min: 0.6 mL)

Unacceptable Conditions

Plasma.

Storage/Transport Temperature

Refrigerated.

Stability (from collection to initiation)

After separation from cells: Ambient: 24 hours; Refrigerated: 1 week; Frozen: 1 month (avoid repeated freeze/thaw cycles)

Remarks

Patient gestational age required.
Ordering

Performed

Sun-Sat

Methodology

Quantitative Chemiluminescent Immunoassay

Reported

1-2 days

Synonyms

  • E3 with Estriol
  • LAB3152
  • EST

Ordering Recommendations

Screening test for fetal aneuploidy in conjunction with other biomarkers and ultrasonography. Indicator of fetal well-being and placental function.
Result Interpretation

Reference Interval

Effective November 19, 2012
Based on gestational age:
25 weeks1.9 - 6.7 ng/mL
26 weeks2.0 - 7.3 ng/mL
27 - 29 weeks2.1 - 9.1 ng/mL
30 - 31 weeks2.4 - 10.6 ng/mL
32 - 37 weeks2.6 - 16.7 ng/mL
Nonpregnant FemaleLess than 0.08 ng/mL
MaleLess than 0.16 ng/mL

Administrative

CPT Codes

82677

ESTROGENS FRACTIONATED BY TMS

LAB980

Collect

Serum separator tube, lavender (EDTA), pink (K2EDTA), or green (sodium or lithium heparin).

Specimen Preparation

Separate serum or plasma from cells within 2 hours of collection. Transfer 0.5 mL serum or plasma to an ARUP Standard Transport Tube. (Min 0.3 mL)

Storage/Transport Temperature

Refrigerated.

Stability (from collection to initiation)

After separation from cells: Ambient: 48 hours; Refrigerated: 1 week; Frozen: 1 month

Performed

Sun-Sat

Methodology

Quantitative High Performance Liquid Chromatography-Tandem Mass Spectrometry

Reported

1-4 days

Synonyms

  • LAB980
  • ESTRONE
  • ESTROGENS TOTAL

Ordering Recommendations

Recommended test for evaluating endogenous estrogen status in postmenopausal women, men, or children.

Reference Interval

Components
Reference Interval
Estradiol, Males, Children or Postmenopausal Females by Tandem Mass Spectrometry
Reference Intervals for Estradiol-Children
Tanner Stages
I
II
III
IV and V		Males
less than 8.0 pg/mL
less than 10.0 pg/mL
1.0-35.0 pg/mL
3.0-35.0 pg/mL		Females
less than 56.0 pg/mL
2.0-133.0 pg/mL
12.0-277.0 pg/mL
2.0-259.0 pg/mL
Age Group
7-9
10-12
13-15
16-17		Males
less than 7.0 pg/mL
less than 11.0 pg/mL
1.0-36.0 pg/mL
3.0-34.0 pg/mL		Females
less than 36.0 pg/mL
1.0-87.0 pg/mL
9.0-249.0 pg/mL
2.0-266.0 pg/mL

Reference Intervals for Estradiol-Adults
Females 18 Years and Older
Males 18 years and Older
Pre-menopausal:
Early Follicular: 30.0-100.0 pg/mL
Late Follicular: 100.0-400.0 pg/mL
Luteal: 50.0-150.0 pg/mL		10.0-42.0 pg/mL
Postmenopausal: 2.0-21.0 pg/mL

Estrone, by Tandem Mass Spectrometry
Reference Intervals for Estrone-Children
Tanner Stages:
I
II
III
IV and V		Males
less than 7.0 pg/mL
less than 11.0 pg/mL
1.0-31.0 pg/mL
2.0-30.0 pg/mL		Females
less than 27.0 pg/mL
1.0-39.0 pg/mL
8.0-117.0 pg/mL
4.0-109.0 pg/mL
Age Group
7-9
10-12
13-15
16-17		Males
less than 7.0 pg/mL
less than 11.0 pg/mL
1.0-30.0 pg/mL
1.0-32.0 pg/mL		Females
less than 20.0 pg/mL
1.0-40.0 pg/mL
8.0-105.0 pg/mL
4.0-133.0 pg/mL

Reference Intervals for Estrone-Adults
Females 18 Years and Older
Males 18 Years and Older
Premenopausal:
Early Follicular: less than 150.0 pg/mL
Late Follicular: 100.0-250.0 pg/mL
Luteal: less than 200.0 pg/mL		9.0-36.0 pg/mL
Postmenopausal: 3.0-32.0 pg/mL

Estrogens Total Calculation
Reference Intervals of Estrogens
Tanner Stages:
I
II
III
IV and V		Males
1.0-11.0
1.0-19.0
3.0-61.0
4.0-62.0		Females
1.0-86.0
3.0-169.0
23.0-351.0
8.0-341.0
Age Group:
7-9
10-12
13-15
16-17		Males
less than 10.0
1.0-19.0
3.0-62.0
4.0-64.0		Females
1.0-48.0
2.0-116.0
15.0-333.0
6.0-354.0

Reference Intervals of Estrogens of Adults
Females 18 Years or Older
Males 18 Years or Older
Total Estrogens (estrone+ estradiol) pg/mL
Total Estrogens (estrone+ estradiol) pg/mL
Pre-menopausal:
Early Follicular: 30.0-250.0
Late Follicular: 200.0-650.0
Luteal: 50.0-350.0		19.0-69.0
Post-menopausal: 5.0-52.0


CPT Codes

82671
Collection

LAB980

Collect

Serum separator tube, lavender (EDTA), pink (K2EDTA), or green (sodium or lithium heparin).

Specimen Preparation

Separate serum or plasma from cells within 2 hours of collection. Transfer 0.5 mL serum or plasma to an ARUP Standard Transport Tube. (Min 0.3 mL)

Storage/Transport Temperature

Refrigerated.

Stability (from collection to initiation)

After separation from cells: Ambient: 48 hours; Refrigerated: 1 week; Frozen: 1 month
Ordering

Performed

Sun-Sat

Methodology

Quantitative High Performance Liquid Chromatography-Tandem Mass Spectrometry

Reported

1-4 days

Synonyms

  • LAB980
  • ESTRONE
  • ESTROGENS TOTAL

Ordering Recommendations

Recommended test for evaluating endogenous estrogen status in postmenopausal women, men, or children.
Result Interpretation

Reference Interval

Components
Reference Interval
Estradiol, Males, Children or Postmenopausal Females by Tandem Mass Spectrometry
Reference Intervals for Estradiol-Children
Tanner Stages
I
II
III
IV and V		Males
less than 8.0 pg/mL
less than 10.0 pg/mL
1.0-35.0 pg/mL
3.0-35.0 pg/mL		Females
less than 56.0 pg/mL
2.0-133.0 pg/mL
12.0-277.0 pg/mL
2.0-259.0 pg/mL
Age Group
7-9
10-12
13-15
16-17		Males
less than 7.0 pg/mL
less than 11.0 pg/mL
1.0-36.0 pg/mL
3.0-34.0 pg/mL		Females
less than 36.0 pg/mL
1.0-87.0 pg/mL
9.0-249.0 pg/mL
2.0-266.0 pg/mL

Reference Intervals for Estradiol-Adults
Females 18 Years and Older
Males 18 years and Older
Pre-menopausal:
Early Follicular: 30.0-100.0 pg/mL
Late Follicular: 100.0-400.0 pg/mL
Luteal: 50.0-150.0 pg/mL		10.0-42.0 pg/mL
Postmenopausal: 2.0-21.0 pg/mL

Estrone, by Tandem Mass Spectrometry
Reference Intervals for Estrone-Children
Tanner Stages:
I
II
III
IV and V		Males
less than 7.0 pg/mL
less than 11.0 pg/mL
1.0-31.0 pg/mL
2.0-30.0 pg/mL		Females
less than 27.0 pg/mL
1.0-39.0 pg/mL
8.0-117.0 pg/mL
4.0-109.0 pg/mL
Age Group
7-9
10-12
13-15
16-17		Males
less than 7.0 pg/mL
less than 11.0 pg/mL
1.0-30.0 pg/mL
1.0-32.0 pg/mL		Females
less than 20.0 pg/mL
1.0-40.0 pg/mL
8.0-105.0 pg/mL
4.0-133.0 pg/mL

Reference Intervals for Estrone-Adults
Females 18 Years and Older
Males 18 Years and Older
Premenopausal:
Early Follicular: less than 150.0 pg/mL
Late Follicular: 100.0-250.0 pg/mL
Luteal: less than 200.0 pg/mL		9.0-36.0 pg/mL
Postmenopausal: 3.0-32.0 pg/mL

Estrogens Total Calculation
Reference Intervals of Estrogens
Tanner Stages:
I
II
III
IV and V		Males
1.0-11.0
1.0-19.0
3.0-61.0
4.0-62.0		Females
1.0-86.0
3.0-169.0
23.0-351.0
8.0-341.0
Age Group:
7-9
10-12
13-15
16-17		Males
less than 10.0
1.0-19.0
3.0-62.0
4.0-64.0		Females
1.0-48.0
2.0-116.0
15.0-333.0
6.0-354.0

Reference Intervals of Estrogens of Adults
Females 18 Years or Older
Males 18 Years or Older
Total Estrogens (estrone+ estradiol) pg/mL
Total Estrogens (estrone+ estradiol) pg/mL
Pre-menopausal:
Early Follicular: 30.0-250.0
Late Follicular: 200.0-650.0
Luteal: 50.0-350.0		19.0-69.0
Post-menopausal: 5.0-52.0


Administrative

CPT Codes

82671

ETHANOL FOR VOLATILE BY GC

LAB4265
ETOH B GC

Collect

One 6.0 mL red top tube, no gel, serum (clot activator).

Patient Preparation

Do NOT use alcohol-based wipes to cleanse the patient's skin prior to venipuncture.

Pediatric Collection

Minimum volume: 1 mL serum.

Unacceptable Conditions

SST or PST Gel separator tubes; specimens drawn in capillary tubes; insufficient sample volume; sample not properly identified; forensic samples.

Storage/Transport Temperature

Internal: Deliver to lab within one hour of collection.
Offsite: Allow to clot for 30 minutes after collection. Centrifuge within one hour of collection. Place at least 1 mL serum in a tightly sealed aliquot container with minimal dead space and transport to lab at 2-8 degrees C (refrigerated or on ice).

Stability (from collection to initiation)

Prior to centrifugation: Ambient, 1 hour

Tightly capped serum aliquot: Ambient, 1 week; Refrigerated (2-8 degrees C), 2 weeks; Frozen (-20 degrees C), 1 month.

Remarks

Do not use alcohol prior to venipuncture. Specimen should be kept closed as much as possible. Specimen should be analyzed as soon as possible after collection. If prolonged storage is anticipated, the addition of fluoride (collected in a grey top tube) is recommended.

Performed by

PCL Clinical Laboratory - Toxicology

Performed

Daily

Methodology

Gas chromatography (GC).

Reported

Same day

Synonyms

  • ETHANOL B
  • ETHAN VLBYGC
  • ETHANOL BLOOD GC

Reference Interval

<5 mg/dL

Performed by

PCL Clinical Laboratory - Toxicology

CPT Codes

82055

Collection

LAB4265
ETOH B GC

Collect

One 6.0 mL red top tube, no gel, serum (clot activator).

Patient Preparation

Do NOT use alcohol-based wipes to cleanse the patient's skin prior to venipuncture.

Pediatric Collection

Minimum volume: 1 mL serum.

Unacceptable Conditions

SST or PST Gel separator tubes; specimens drawn in capillary tubes; insufficient sample volume; sample not properly identified; forensic samples.

Storage/Transport Temperature

Internal: Deliver to lab within one hour of collection.
Offsite: Allow to clot for 30 minutes after collection. Centrifuge within one hour of collection. Place at least 1 mL serum in a tightly sealed aliquot container with minimal dead space and transport to lab at 2-8 degrees C (refrigerated or on ice).

Stability (from collection to initiation)

Prior to centrifugation: Ambient, 1 hour

Tightly capped serum aliquot: Ambient, 1 week; Refrigerated (2-8 degrees C), 2 weeks; Frozen (-20 degrees C), 1 month.

Remarks

Do not use alcohol prior to venipuncture. Specimen should be kept closed as much as possible. Specimen should be analyzed as soon as possible after collection. If prolonged storage is anticipated, the addition of fluoride (collected in a grey top tube) is recommended.

Performed by

PCL Clinical Laboratory - Toxicology

Ordering

Performed

Daily

Methodology

Gas chromatography (GC).

Reported

Same day

Synonyms

  • ETHANOL B
  • ETHAN VLBYGC
  • ETHANOL BLOOD GC
Result Interpretation

Reference Interval

<5 mg/dL

Performed by

PCL Clinical Laboratory - Toxicology

Administrative

CPT Codes

82055

ETHANOL, BLOOD

LAB3051

Collect

One 4.5 mL green top with gel (PST), (lithium heparin plasma).

Pediatric Collection

Minimum volume: 2.0 mL whole blood.

Unacceptable Conditions

Incorrect container; insufficient volume, specimen not properly identified.

Storage/Transport Temperature

Internal: Deliver to lab immediately.
Offsite: Separate serum or plasma from cells as soon as possible. Cap immediately to prevent evaporation. Make sure tube or container is tightly capped.

Stability (from collection to initiation)

Plasma/Serum: Room temp: 48 hrs; Refrigerated: 2 weeks; Frozen: 4 weeks.

Remarks

Do not use alcohol wipes for venipuncture. The specimen should be analyzed as soon as possible. If stored, refrigerate and keep sample sealed. Assay within 24 hours.

Performed by

PCL Clinical Laboratory - Core

Performed

Daily

Methodology

Enzymatic

Reported

Same day

Synonyms

  • -910
  • LAB3051

Reference Interval

Effective 05/20/2014:

Not detected.

Interpretive Data

Effective 05/20/2014:

80 mg/dL is consistent with a Blood Alcohol Level of 0.08%.

Performed by

PCL Clinical Laboratory - Core

CPT Codes

82055

Collection

LAB3051

Collect

One 4.5 mL green top with gel (PST), (lithium heparin plasma).

Pediatric Collection

Minimum volume: 2.0 mL whole blood.

Unacceptable Conditions

Incorrect container; insufficient volume, specimen not properly identified.

Storage/Transport Temperature

Internal: Deliver to lab immediately.
Offsite: Separate serum or plasma from cells as soon as possible. Cap immediately to prevent evaporation. Make sure tube or container is tightly capped.

Stability (from collection to initiation)

Plasma/Serum: Room temp: 48 hrs; Refrigerated: 2 weeks; Frozen: 4 weeks.

Remarks

Do not use alcohol wipes for venipuncture. The specimen should be analyzed as soon as possible. If stored, refrigerate and keep sample sealed. Assay within 24 hours.

Performed by

PCL Clinical Laboratory - Core

Ordering

Performed

Daily

Methodology

Enzymatic

Reported

Same day

Synonyms

  • -910
  • LAB3051
Result Interpretation

Reference Interval

Effective 05/20/2014:

Not detected.

Interpretive Data

Effective 05/20/2014:

80 mg/dL is consistent with a Blood Alcohol Level of 0.08%.

Performed by

PCL Clinical Laboratory - Core

Administrative

CPT Codes

82055

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