EVEROLIMUS LEVEL

LAB3585

Collect

5 mL purple top (EDTA) tube - whole blood

Storage/Transport Temperature

Internal: Deliver to lab immediately at room temperature
Offsite: 5 mL purple top (EDTA) - whole blood at 2-8°C. [Min vol: 2 mL) or ship whole blood frozen in dry ice.

Stability (from collection to initiation)

Ambient: 24 hours; Refrigerated : 5 days; Frozen -70 : 6 months

Performed by

UCD Anesthesiology Research & Development Lab

Performed

Daily, MON-FRI, if sample is received in lab before 10 am (1000).

Methodology

Liquid Chromatography/Mass Spectrometry

Reported

Same day

Synonyms

  • Zortress Level - Everolimus
  • LAB3585
  • EVEROL

Reference Interval

Updated 10/30/14 to reflect the FDA recommended therapeutic range:

Reference Interval:  3.00-8.00 ng/mL

Toxic:  >25 ng/mL

Performed by

UCD Anesthesiology Research & Development Lab

CPT Codes

80169

Collection

LAB3585

Collect

5 mL purple top (EDTA) tube - whole blood

Storage/Transport Temperature

Internal: Deliver to lab immediately at room temperature
Offsite: 5 mL purple top (EDTA) - whole blood at 2-8°C. [Min vol: 2 mL) or ship whole blood frozen in dry ice.

Stability (from collection to initiation)

Ambient: 24 hours; Refrigerated : 5 days; Frozen -70 : 6 months

Performed by

UCD Anesthesiology Research & Development Lab

Ordering

Performed

Daily, MON-FRI, if sample is received in lab before 10 am (1000).

Methodology

Liquid Chromatography/Mass Spectrometry

Reported

Same day

Synonyms

  • Zortress Level - Everolimus
  • LAB3585
  • EVEROL
Result Interpretation

Reference Interval

Updated 10/30/14 to reflect the FDA recommended therapeutic range:

Reference Interval:  3.00-8.00 ng/mL

Toxic:  >25 ng/mL

Performed by

UCD Anesthesiology Research & Development Lab

Administrative

CPT Codes

80169

E. COLI SHIGA-LIKE TOXIN [EIA]

LAB1318

Collect

Stool. OR actively growing isolate of E. coli, in pure culture.

Specimen Preparation

Stool: Place 5 mL stool in enteric transport media (Cary-Blair) (ARUP Supply #29799) immediately after collection. Available online through eSupply using ARUP Connect™ or contact ARUP Client Services at (800) 522-2787. (Min: 1 mL)
E. coli Isolate:
Transport sealed container with pure culture on agar slant or on a swab in bacterial transport media. Place each specimen in an individually sealed bag.

Unacceptable Conditions

Specimens or isolates from sources other than stool.

Storage/Transport Temperature

Stool: Refrigerated.
E. coli
Isolate:
Room temperature.

Stability (from collection to initiation)

Stool in Transport Media: Ambient: 1 hour; Refrigerated: 72 hours; Frozen: 1 week
E. coli
Isolate:
Ambient: 1 week; Refrigerated: 1 week; Frozen: Unacceptable

Notes

This test will identify the presence of E. coli Shiga-like toxin, however it cannot determine specific of strains of E. coli. (e.g., E. coli O157:H7)

Performed

Sun-Sat

Methodology

Qualitative Enzyme Immunoassay

Reported

Within 2 days

Synonyms

  • LAB1318
  • ECSLT AG

Additional Technical Information

Ordering Recommendations

Test detects the Shiga toxins, sensitive markers of toxigenic Escherichia coli. CDC recommends stool specimens also be cultured for E. coli 0157:H7 (0157 STEC).

Reference Interval

Negative

Interpretive Data

By report.

CPT Codes

87427
Collection

LAB1318

Collect

Stool. OR actively growing isolate of E. coli, in pure culture.

Specimen Preparation

Stool: Place 5 mL stool in enteric transport media (Cary-Blair) (ARUP Supply #29799) immediately after collection. Available online through eSupply using ARUP Connect™ or contact ARUP Client Services at (800) 522-2787. (Min: 1 mL)
E. coli Isolate:
Transport sealed container with pure culture on agar slant or on a swab in bacterial transport media. Place each specimen in an individually sealed bag.

Unacceptable Conditions

Specimens or isolates from sources other than stool.

Storage/Transport Temperature

Stool: Refrigerated.
E. coli
Isolate:
Room temperature.

Stability (from collection to initiation)

Stool in Transport Media: Ambient: 1 hour; Refrigerated: 72 hours; Frozen: 1 week
E. coli
Isolate:
Ambient: 1 week; Refrigerated: 1 week; Frozen: Unacceptable

Notes

This test will identify the presence of E. coli Shiga-like toxin, however it cannot determine specific of strains of E. coli. (e.g., E. coli O157:H7)
Ordering

Performed

Sun-Sat

Methodology

Qualitative Enzyme Immunoassay

Reported

Within 2 days

Synonyms

  • LAB1318
  • ECSLT AG

Additional Technical Information

Ordering Recommendations

Test detects the Shiga toxins, sensitive markers of toxigenic Escherichia coli. CDC recommends stool specimens also be cultured for E. coli 0157:H7 (0157 STEC).
Result Interpretation

Reference Interval

Negative

Interpretive Data

By report.

Administrative

CPT Codes

87427

EBV ACUTE PANEL

LAB3615

EBV ACUTE

Collect

One 5.0 mL gold or red top with gel (SST), (clot activator serum).

Also acceptable: One 6.0 mL red top no gel, serum (clot activator).

Pediatric Collection

Minimum volume 0.5 mL serum.

Unacceptable Conditions

Lipemic and/or grossly hemolyzed specimens; presence of particulate matter or obvious bacterial contamination; specimen not properly identified; incorrect container; insufficient sample volume.

Storage/Transport Temperature

Internal: Allow to clot for 30 minutes, then deliver to lab at ambient temperature.

Offsite: Allow to clot for 30 minutes, then centrifuge immediately.  Place at least 2 mL serum in an aliquot container.  If tested within 24 hours of collection, transport at 2-8 degrees C.  If tested more than 24 hours after collection, transport frozen.

Stability (from collection to initiation)

Whole blood, ambient (19-24 degrees C): 1 hour

Serum, refrigerated (2-8 degrees C): 2 days

Serum, frozen (-20 degrees C): 1 month

Remarks

EBV Acute Panel includes:

  • Viral Capsid Antigen Antibody IgG (VCAIGG)
  • Viral Capsid Antigen Antibody IgM (EBV IGM)

Performed by

PCL Clinical Laboratory - Special Chemistry

Performed

Thursdays

Methodology

Chemiluminesent Immunoassay (CLIA)

Reported

Same day

Synonyms

  • EBV IGM
  • EBV IGG
  • LAB3615
  • EBV ACUTE
  • EPSTEIN-BARR VIRUS ACUTE PANEL

Performed by

PCL Clinical Laboratory - Special Chemistry

CPT Codes

86665 (2)

Collection

LAB3615

EBV ACUTE

Collect

One 5.0 mL gold or red top with gel (SST), (clot activator serum).

Also acceptable: One 6.0 mL red top no gel, serum (clot activator).

Pediatric Collection

Minimum volume 0.5 mL serum.

Unacceptable Conditions

Lipemic and/or grossly hemolyzed specimens; presence of particulate matter or obvious bacterial contamination; specimen not properly identified; incorrect container; insufficient sample volume.

Storage/Transport Temperature

Internal: Allow to clot for 30 minutes, then deliver to lab at ambient temperature.

Offsite: Allow to clot for 30 minutes, then centrifuge immediately.  Place at least 2 mL serum in an aliquot container.  If tested within 24 hours of collection, transport at 2-8 degrees C.  If tested more than 24 hours after collection, transport frozen.

Stability (from collection to initiation)

Whole blood, ambient (19-24 degrees C): 1 hour

Serum, refrigerated (2-8 degrees C): 2 days

Serum, frozen (-20 degrees C): 1 month

Remarks

EBV Acute Panel includes:

  • Viral Capsid Antigen Antibody IgG (VCAIGG)
  • Viral Capsid Antigen Antibody IgM (EBV IGM)

Performed by

PCL Clinical Laboratory - Special Chemistry

Ordering

Performed

Thursdays

Methodology

Chemiluminesent Immunoassay (CLIA)

Reported

Same day

Synonyms

  • EBV IGM
  • EBV IGG
  • LAB3615
  • EBV ACUTE
  • EPSTEIN-BARR VIRUS ACUTE PANEL
Result Interpretation

Performed by

PCL Clinical Laboratory - Special Chemistry

Administrative

CPT Codes

86665 (2)

EBV FOLLOW-UP PANEL

LAB3616

EBV FOLLOW

Collect

One 5.0 mL gold or red top with gel (SST), (clot activator serum).

Also acceptable: One 6.0 mL red top no gel, serum (clot activator).

Pediatric Collection

Minuimum volume: 0.5 mL serum

Unacceptable Conditions

Lipemic and/or grossly hemolyzed specimens; presence of particulate matter or obvious bacterial contamination; specimen not properly identified; incorrect container; insufficient sample volume.

Storage/Transport Temperature

Internal: Allow to clot for 30 minutes, then deliver to lab at ambient temperature.

Offsite: Allow to clot for 30 minutes, then centrifuge immediately.  Place at least 2 mL serum in an aliquot container.  If tested within 24 hours of collection, transport at 2-8 degrees C.  If tested more than 24 hours after collection, transport frozen.

Stability (from collection to initiation)

Whole blood, ambient (19-24 degrees C): 1 hour

Serum, refrigerated (2-8 degrees C): 2 days

Serum, frozen (-20 degrees C): 1 month

Remarks

EBV Follow-up Panel includes:

  • Viral Capsid Antigen Antibody IgG (VCAIGG)
  • Viral Capsid Antigen Antibody IgM (EBV IGM)
  • Epstein Barr Nuclear Antigen Antibody IgG (EBNA)

Performed by

PCL Clinical Laboratory - Special Chemistry

Performed

Thursdays

Methodology

Chemiluminescent Immunoassay (CLIA)

Reported

Same day

Synonyms

  • EBV IGM
  • EBNA IGG
  • EBV IGG
  • LAB3616
  • EPSTEIN-BARR VIRUS FOLLOW UP PANEL
  • EBV FOLLOW

Performed by

PCL Clinical Laboratory - Special Chemistry

CPT Codes

86664 (1); 86665 (2);

Collection

LAB3616

EBV FOLLOW

Collect

One 5.0 mL gold or red top with gel (SST), (clot activator serum).

Also acceptable: One 6.0 mL red top no gel, serum (clot activator).

Pediatric Collection

Minuimum volume: 0.5 mL serum

Unacceptable Conditions

Lipemic and/or grossly hemolyzed specimens; presence of particulate matter or obvious bacterial contamination; specimen not properly identified; incorrect container; insufficient sample volume.

Storage/Transport Temperature

Internal: Allow to clot for 30 minutes, then deliver to lab at ambient temperature.

Offsite: Allow to clot for 30 minutes, then centrifuge immediately.  Place at least 2 mL serum in an aliquot container.  If tested within 24 hours of collection, transport at 2-8 degrees C.  If tested more than 24 hours after collection, transport frozen.

Stability (from collection to initiation)

Whole blood, ambient (19-24 degrees C): 1 hour

Serum, refrigerated (2-8 degrees C): 2 days

Serum, frozen (-20 degrees C): 1 month

Remarks

EBV Follow-up Panel includes:

  • Viral Capsid Antigen Antibody IgG (VCAIGG)
  • Viral Capsid Antigen Antibody IgM (EBV IGM)
  • Epstein Barr Nuclear Antigen Antibody IgG (EBNA)

Performed by

PCL Clinical Laboratory - Special Chemistry

Ordering

Performed

Thursdays

Methodology

Chemiluminescent Immunoassay (CLIA)

Reported

Same day

Synonyms

  • EBV IGM
  • EBNA IGG
  • EBV IGG
  • LAB3616
  • EPSTEIN-BARR VIRUS FOLLOW UP PANEL
  • EBV FOLLOW
Result Interpretation

Performed by

PCL Clinical Laboratory - Special Chemistry

Administrative

CPT Codes

86664 (1); 86665 (2);

ECHINOCOCCUS AB - IGG [ELISA]

LAB1234

Collect

Serum separator tube (SST).

Specimen Preparation

Separate serum from cells ASAP or within 2 hours of collection. Transfer 1 mL serum to an ARUP Standard Transport Tube. (Min: 0.15 mL) Parallel testing is preferred and convalescent specimens must be received within 30 days from receipt of acute specimens. Mark specimens plainly as acute or convalescent.

Unacceptable Conditions

Contaminated or severely lipemic specimens.

Storage/Transport Temperature

Refrigerated.

Stability (from collection to initiation)

After separation from cells: Ambient: 48 hours; Refrigerated: 2 weeks; Frozen: 1 year (avoid repeated freeze/thaw cycles)

Performed

Mon, Thu

Methodology

Semi-Quantitative Enzyme-Linked Immunosorbent Assay

Reported

1-5 days

Synonyms

  • IgG Ab
  • Echinococcus IgG Antibody
  • Hyatid Disease
  • Tapeworm IgG Ab
  • LAB1234
  • ECHINO IGG

Ordering Recommendations

Adjunct to other diagnostic tests (eg, imaging) for echinococcosis. Patient's travel history is necessary to aid in test interpretation.

Reference Interval

0.00-0.89 IV: Negative - No significant level of Echinococcus IgG antibody detected.
0.90-1.09 IV: Equivocal - Questionable presence of Echinococcus IgG antibody detected.  Repeat testing in 10-14 days may be helpful.
1.10 IV or greater: Positive - Presence of IgG antibody to Echinococcus detected, suggestive of current or past infection.

Interpretive Data

Patients with collagen vascular diseases, hepatic cirrhosis, schistosomiasis, and other parasitic infections can produce false-positive results. There is a strong cross-reaction between echinococcosis- and cysticercosis-positive sera.

Seroconversion between acute and convalescent sera is considered strong evidence of recent infection. The best evidence for infection is a significant change on two appropriately timed specimens where both tests are done in the same laboratory at the same time.

CPT Codes

86682
Collection

LAB1234

Collect

Serum separator tube (SST).

Specimen Preparation

Separate serum from cells ASAP or within 2 hours of collection. Transfer 1 mL serum to an ARUP Standard Transport Tube. (Min: 0.15 mL) Parallel testing is preferred and convalescent specimens must be received within 30 days from receipt of acute specimens. Mark specimens plainly as acute or convalescent.

Unacceptable Conditions

Contaminated or severely lipemic specimens.

Storage/Transport Temperature

Refrigerated.

Stability (from collection to initiation)

After separation from cells: Ambient: 48 hours; Refrigerated: 2 weeks; Frozen: 1 year (avoid repeated freeze/thaw cycles)
Ordering

Performed

Mon, Thu

Methodology

Semi-Quantitative Enzyme-Linked Immunosorbent Assay

Reported

1-5 days

Synonyms

  • IgG Ab
  • Echinococcus IgG Antibody
  • Hyatid Disease
  • Tapeworm IgG Ab
  • LAB1234
  • ECHINO IGG

Ordering Recommendations

Adjunct to other diagnostic tests (eg, imaging) for echinococcosis. Patient's travel history is necessary to aid in test interpretation.
Result Interpretation

Reference Interval

0.00-0.89 IV: Negative - No significant level of Echinococcus IgG antibody detected.
0.90-1.09 IV: Equivocal - Questionable presence of Echinococcus IgG antibody detected.  Repeat testing in 10-14 days may be helpful.
1.10 IV or greater: Positive - Presence of IgG antibody to Echinococcus detected, suggestive of current or past infection.

Interpretive Data

Patients with collagen vascular diseases, hepatic cirrhosis, schistosomiasis, and other parasitic infections can produce false-positive results. There is a strong cross-reaction between echinococcosis- and cysticercosis-positive sera.

Seroconversion between acute and convalescent sera is considered strong evidence of recent infection. The best evidence for infection is a significant change on two appropriately timed specimens where both tests are done in the same laboratory at the same time.

Administrative

CPT Codes

86682

ECHOVIRUS ANTIBODIES

LAB3220

Collect

Serum separator tube or plain red. OR CSF.

Specimen Preparation

Separate serum from cells within 2 hours of collection. Transport 1 mL serum or CSF. (Min: 0.3 mL) Parallel testing is preferred and convalescent samples must be received within 30 days from receipt of acute samples. Mark samples plainly as "acute" or "convalescent."

Unacceptable Conditions

Plasma.

Storage/Transport Temperature

Refrigerated.

Stability (from collection to initiation)

Ambient: 48 hours; Refrigerated: 2 weeks; Frozen: 1 year (avoid repeated freeze/thaw cycles)

Performed

Mon-Fri

Methodology

Semi-Quantitative Serum Neutralization

Reported

6-9 days

Synonyms

  • LAB3220
  • ECHO

Ordering Recommendations

Detect neutralizing antibodies to echovirus types 6, 7, 9, 11, and 30.

Reference Interval

Echovirus 6:  Less than 1:10
Echovirus 7:  Less than 1:10
Echovirus 9:  Less than 1:10
Echovirus 11: Less than 1:10
Echovirus 30: Less than 1:10

Interpretive Data

Single positive antibody titers of greater than or equal to 1:80 may indicate past or current infection.  Seroconversion or an increase in titers between acute and convalescent sera of at least fourfold is considered strong evidence of current or recent infection.

CPT Codes

86658 x5
Collection

LAB3220

Collect

Serum separator tube or plain red. OR CSF.

Specimen Preparation

Separate serum from cells within 2 hours of collection. Transport 1 mL serum or CSF. (Min: 0.3 mL) Parallel testing is preferred and convalescent samples must be received within 30 days from receipt of acute samples. Mark samples plainly as "acute" or "convalescent."

Unacceptable Conditions

Plasma.

Storage/Transport Temperature

Refrigerated.

Stability (from collection to initiation)

Ambient: 48 hours; Refrigerated: 2 weeks; Frozen: 1 year (avoid repeated freeze/thaw cycles)
Ordering

Performed

Mon-Fri

Methodology

Semi-Quantitative Serum Neutralization

Reported

6-9 days

Synonyms

  • LAB3220
  • ECHO

Ordering Recommendations

Detect neutralizing antibodies to echovirus types 6, 7, 9, 11, and 30.
Result Interpretation

Reference Interval

Echovirus 6:  Less than 1:10
Echovirus 7:  Less than 1:10
Echovirus 9:  Less than 1:10
Echovirus 11: Less than 1:10
Echovirus 30: Less than 1:10

Interpretive Data

Single positive antibody titers of greater than or equal to 1:80 may indicate past or current infection.  Seroconversion or an increase in titers between acute and convalescent sera of at least fourfold is considered strong evidence of current or recent infection.

Administrative

CPT Codes

86658 x5

ED ABUSE URINE TOXICOLOGY SCREEN (UTOX PANEL FOR ED)

LAB3292

DOA ED8

Collect

20.0 mL random urine in a plastic urine container.

Larger volumes are encouraged to provide enough sample for confirmation testing.

Pediatric Collection

Minimum volume 5.0mL random urine

Unacceptable Conditions

Paper cups, adulterated specimens, insufficient volume, sample not properly identified.

Storage/Transport Temperature

Internal: Deliver to lab immediately.
Offsite: Transport to laboratory at 2-8 degrees C.

Stability (from collection to initiation)

Ambient: 2 days, Refrigerated: 7 days, Frozen: Indefinitely.

Remarks

Detection Cutoffs are: Amphetamine/Metamphetamine 1000 ng/mL, Barbituate 200 ng/mL, Benzodiazepine 200 ng/mL, Cannabinoids 50 ng/mL, Cocaine 300 ng/mL, Opiates 300 ng/mL, Phencyclidine (PCP) 25 ng/mL, Ethanol 10 mg/dL

Performed by

PCL Clinical Laboratory - Core

Performed

Daily

Methodology

Homogenous enzyme immunoassay.

Reported

Same day

Synonyms

  • ED URINE TOXICOLOGY SCREEN
  • LAB3292

Performed by

PCL Clinical Laboratory - Core

CPT Codes

80101 (8)

Medicare patients: G0434 (1)

Collection

LAB3292

DOA ED8

Collect

20.0 mL random urine in a plastic urine container.

Larger volumes are encouraged to provide enough sample for confirmation testing.

Pediatric Collection

Minimum volume 5.0mL random urine

Unacceptable Conditions

Paper cups, adulterated specimens, insufficient volume, sample not properly identified.

Storage/Transport Temperature

Internal: Deliver to lab immediately.
Offsite: Transport to laboratory at 2-8 degrees C.

Stability (from collection to initiation)

Ambient: 2 days, Refrigerated: 7 days, Frozen: Indefinitely.

Remarks

Detection Cutoffs are: Amphetamine/Metamphetamine 1000 ng/mL, Barbituate 200 ng/mL, Benzodiazepine 200 ng/mL, Cannabinoids 50 ng/mL, Cocaine 300 ng/mL, Opiates 300 ng/mL, Phencyclidine (PCP) 25 ng/mL, Ethanol 10 mg/dL

Performed by

PCL Clinical Laboratory - Core

Ordering

Performed

Daily

Methodology

Homogenous enzyme immunoassay.

Reported

Same day

Synonyms

  • ED URINE TOXICOLOGY SCREEN
  • LAB3292
Result Interpretation

Performed by

PCL Clinical Laboratory - Core

Administrative

CPT Codes

80101 (8)

Medicare patients: G0434 (1)

EHRLICHIA CHAFFEENSIS AB G/M

LAB794

Collect

Serum separator tube.

Specimen Preparation

Separate serum from cells ASAP or within 2 hours of collection. Transfer 1 mL serum to an ARUP Standard Transport Tube. (Min: 0.05 mL) Parallel testing is preferred and convalescent specimens must be received within 30 days from receipt of the acute specimens. Mark specimens plainly as acute or convalescent.

Unacceptable Conditions

Contaminated, hemolyzed, or severely lipemic specimens.

Storage/Transport Temperature

Refrigerated.

Stability (from collection to initiation)

After separation from cells: Ambient: 48 hours; Refrigerated: 2 weeks; Frozen: 1 year (avoid repeated freeze/thaw cycles)

Notes

Human ehrlichiosis is a tick-borne disease caused by rickettsial-like agents. Two forms, human monocytic ehrlichiosis (HME) and human granulocytic ehrlichiosis (HGE), have been described. HME is often referred to as "spotless" or rashless Rocky Mountain spotted fever, and has been reported in various regions of the United States. The causative agent of HME has been identified as Ehrlichia chaffeensis. Infected individuals produce specific antibodies to Ehrlichia chaffeensis which can be detected by an immunofluorescent antibody (IFA) test.

Performed

Tue, Fri

Methodology

Semi-Quantitative Indirect Fluorescent Antibody

Reported

1-5 days

Synonyms

  • Human Monocytic Ehrlichiosis (HME), HME Antibody IgG & IgM
  • LAB794

Ordering Recommendations

Diagnose infection from Ehrlichia chaffeensis.

Reference Interval

Components
Reference Interval
Ehrlichia chaffeensis Antibody, IgG by IFA< 1:64  Negative-No significant level of Ehrlichia chaffeensis IgG antibody detected.
1:64-1:128  Equivocal-Questionable presence of Ehrlichia chaffeensis IgG antibody detected.  Repeat testing in 10-14 days may be helpful.
≥1:256  Positive-Presence of IgG antibody to Ehrlichia chaffeensis detected, suggestive of current or past infection.
Ehrlichia chaffeensis Antibody, IgM by IFA< 1:16  Negative-No significant level of Ehrlichia chaffeensis IgM antibody detected.
≥ 1:16  Positive-Presence of IgM antibody to Ehrlichia chaffeensis detected, suggestive of current or recent infection.

Interpretive Data

Refer to individual components.

CPT Codes

86666 x2
Collection

LAB794

Collect

Serum separator tube.

Specimen Preparation

Separate serum from cells ASAP or within 2 hours of collection. Transfer 1 mL serum to an ARUP Standard Transport Tube. (Min: 0.05 mL) Parallel testing is preferred and convalescent specimens must be received within 30 days from receipt of the acute specimens. Mark specimens plainly as acute or convalescent.

Unacceptable Conditions

Contaminated, hemolyzed, or severely lipemic specimens.

Storage/Transport Temperature

Refrigerated.

Stability (from collection to initiation)

After separation from cells: Ambient: 48 hours; Refrigerated: 2 weeks; Frozen: 1 year (avoid repeated freeze/thaw cycles)

Notes

Human ehrlichiosis is a tick-borne disease caused by rickettsial-like agents. Two forms, human monocytic ehrlichiosis (HME) and human granulocytic ehrlichiosis (HGE), have been described. HME is often referred to as "spotless" or rashless Rocky Mountain spotted fever, and has been reported in various regions of the United States. The causative agent of HME has been identified as Ehrlichia chaffeensis. Infected individuals produce specific antibodies to Ehrlichia chaffeensis which can be detected by an immunofluorescent antibody (IFA) test.
Ordering

Performed

Tue, Fri

Methodology

Semi-Quantitative Indirect Fluorescent Antibody

Reported

1-5 days

Synonyms

  • Human Monocytic Ehrlichiosis (HME), HME Antibody IgG & IgM
  • LAB794

Ordering Recommendations

Diagnose infection from Ehrlichia chaffeensis.
Result Interpretation

Reference Interval

Components
Reference Interval
Ehrlichia chaffeensis Antibody, IgG by IFA< 1:64  Negative-No significant level of Ehrlichia chaffeensis IgG antibody detected.
1:64-1:128  Equivocal-Questionable presence of Ehrlichia chaffeensis IgG antibody detected.  Repeat testing in 10-14 days may be helpful.
≥1:256  Positive-Presence of IgG antibody to Ehrlichia chaffeensis detected, suggestive of current or past infection.
Ehrlichia chaffeensis Antibody, IgM by IFA< 1:16  Negative-No significant level of Ehrlichia chaffeensis IgM antibody detected.
≥ 1:16  Positive-Presence of IgM antibody to Ehrlichia chaffeensis detected, suggestive of current or recent infection.

Interpretive Data

Refer to individual components.

Administrative

CPT Codes

86666 x2

EHRLICHIA/ANAPLASMA PCR

LAB3946

Collect

Lavender (EDTA) or pink (K2EDTA).

Specimen Preparation

Transport 1 mL whole blood. (Min: 0.6 mL)

Unacceptable Conditions

Heparinized specimens.

Storage/Transport Temperature

Refrigerated

Stability (from collection to initiation)

Ambient: 24 hours; Refrigerated: 1 week; Frozen: 1 week

Notes

This test detects and speciates Anaplasma phagocytophilum; Ehrlichia chaffeensis; E. ewingii/E. canis; E. muris-like. The nucleic acid detected from E. ewingii and E. canis cannot be differentiated by this test. A result of "Detected" for E. ewingii/canis indicates the presence of either of these two organisms in the specimen.

Performed

Sun-Sat

Methodology

Qualitative Polymerase Chain Reaction

Reported

1-3 days

Synonyms

  • Ehrlichia chaffeensis
  • E. canis
  • E. muris-like; E. ewingii
  • Anaplasma phagocytophilum
  • LAB3946
  • EHR ANAPCR

Ordering Recommendations

Preferred panel for diagnosing possible tick-borne disease (ie, Anaplasmosis or Ehrlichiosis) during the acute phase of the disease.

Interpretive Data

A negative result does not rule out the presence of PCR inhibitors in the patient specimen or test-specific nucleic acid in concentrations below the level of detection by this test.

CPT Codes

87798 x4
Collection

LAB3946

Collect

Lavender (EDTA) or pink (K2EDTA).

Specimen Preparation

Transport 1 mL whole blood. (Min: 0.6 mL)

Unacceptable Conditions

Heparinized specimens.

Storage/Transport Temperature

Refrigerated

Stability (from collection to initiation)

Ambient: 24 hours; Refrigerated: 1 week; Frozen: 1 week

Notes

This test detects and speciates Anaplasma phagocytophilum; Ehrlichia chaffeensis; E. ewingii/E. canis; E. muris-like. The nucleic acid detected from E. ewingii and E. canis cannot be differentiated by this test. A result of "Detected" for E. ewingii/canis indicates the presence of either of these two organisms in the specimen.
Ordering

Performed

Sun-Sat

Methodology

Qualitative Polymerase Chain Reaction

Reported

1-3 days

Synonyms

  • Ehrlichia chaffeensis
  • E. canis
  • E. muris-like; E. ewingii
  • Anaplasma phagocytophilum
  • LAB3946
  • EHR ANAPCR

Ordering Recommendations

Preferred panel for diagnosing possible tick-borne disease (ie, Anaplasmosis or Ehrlichiosis) during the acute phase of the disease.
Result Interpretation

Interpretive Data

A negative result does not rule out the presence of PCR inhibitors in the patient specimen or test-specific nucleic acid in concentrations below the level of detection by this test.

Administrative

CPT Codes

87798 x4

ELECTROLYTE PANEL

LAB16

LYTES

Collect

One 4.5 mL Green top tube with gel separator

Also acceptable:

Red top tube with or without a gel separator, Green top tube without gel separator.

Minimum volume: 0.4mL serum/plasma

Unacceptable Conditions

Sample not properly identified; incorrect container; insufficient sample volume.

Storage/Transport Temperature

Internal: Deliver to lab immediately.
Offsite:  Green tops: Centrifuge within 30 minutes of collection. Red tops: Allow 20 minutes for Red top to clot. Centrifuge within 30 minutes of collection.

Stability (from collection to initiation)

Refer to individual components for stability.

Performed by

PCL Clinical Laboratory - Core

Notes

For laboratories to bill Medicare, each component of a panel must be medically necessary for the treatment or diagnosis of the patient. All tests listed may be ordered individually.

Performed

Upon receipt

Methodology

Refer to individual components for methodology. Panel includes: Na, K, Cl, CO2.

Reported

Same day

Synonyms

  • LAB16
  • LYTES

Reference Interval

Effective 05/20/2014:

Component Low High Units
SODIUM,SERUM/PLASMA 133 145 mmol/L
POTASSIUM, SERUM/PLASMA 3.5 5.1 mmol/L
CHLORIDE, SERUM/PLASMA 98 108 mmol/L
CARBON DIOXIDE 21 31 mmol/L
Anion Gap 7 16 mmol/L

 

Before 05/20/2014:

Component Sex From Age To Age Normal Low Normal High Units
POTASSIUM, SERUM/PLASMA M/F 0 1D 3.5 6.0 mmol/L
  M/F 1D 16 3.5 5.0 mmol/L
  M/F 16 150 3.3 5.0 mmol/L
SODIUM,SERUM/PLASMA M/F 0 1M 135 145 mmol/L
  M/F 1M 150 133 145 mmol/L
CARBON DIOXIDE M/F 0 150 22 32 mmol/L
CHLORIDE, SERUM/PLASMA M/F 0 16 97 108 mmol/L
  M/F 16 150 101 111 mmol/L

Interpretive Data

Adult reference ranges.

Performed by

PCL Clinical Laboratory - Core

CPT Codes

80051

Collection

LAB16

LYTES

Collect

One 4.5 mL Green top tube with gel separator

Also acceptable:

Red top tube with or without a gel separator, Green top tube without gel separator.

Minimum volume: 0.4mL serum/plasma

Unacceptable Conditions

Sample not properly identified; incorrect container; insufficient sample volume.

Storage/Transport Temperature

Internal: Deliver to lab immediately.
Offsite:  Green tops: Centrifuge within 30 minutes of collection. Red tops: Allow 20 minutes for Red top to clot. Centrifuge within 30 minutes of collection.

Stability (from collection to initiation)

Refer to individual components for stability.

Performed by

PCL Clinical Laboratory - Core

Notes

For laboratories to bill Medicare, each component of a panel must be medically necessary for the treatment or diagnosis of the patient. All tests listed may be ordered individually.

Ordering

Performed

Upon receipt

Methodology

Refer to individual components for methodology. Panel includes: Na, K, Cl, CO2.

Reported

Same day

Synonyms

  • LAB16
  • LYTES
Result Interpretation

Reference Interval

Effective 05/20/2014:

Component Low High Units
SODIUM,SERUM/PLASMA 133 145 mmol/L
POTASSIUM, SERUM/PLASMA 3.5 5.1 mmol/L
CHLORIDE, SERUM/PLASMA 98 108 mmol/L
CARBON DIOXIDE 21 31 mmol/L
Anion Gap 7 16 mmol/L

 

Before 05/20/2014:

Component Sex From Age To Age Normal Low Normal High Units
POTASSIUM, SERUM/PLASMA M/F 0 1D 3.5 6.0 mmol/L
  M/F 1D 16 3.5 5.0 mmol/L
  M/F 16 150 3.3 5.0 mmol/L
SODIUM,SERUM/PLASMA M/F 0 1M 135 145 mmol/L
  M/F 1M 150 133 145 mmol/L
CARBON DIOXIDE M/F 0 150 22 32 mmol/L
CHLORIDE, SERUM/PLASMA M/F 0 16 97 108 mmol/L
  M/F 16 150 101 111 mmol/L

Interpretive Data

Adult reference ranges.

Performed by

PCL Clinical Laboratory - Core

Administrative

CPT Codes

80051

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