Tests Catalogs

ANTI-SCL 70, ANTI CENTROMERE

LAB5140 Anti-SCL-70

LAB4570 Anti-Centromere

Collect

5.0 mL, gold or red top with gel (SST), (clot activator serum).

Unacceptable Conditions

Excessive hemolysis, chylous serum, gross contamination, inadequate volume of blood, inadequate patient and/or specimen identification.

Storage/Transport Temperature

Internal: Deliver to lab immediately
Offsite: 2 mL Separate serum from cells and deliver to the lab refrigerated.

Stability (from collection to initiation)

Refrigerated: 1-2 weeks; Frozen: Indefinitely.

Remarks

Serum must be removed from clot within 2 hours after collection. Refrigerate.

Performed by

PCL Clinical Laboratory

Performed

Mon - Fri

Methodology

Immunodiffusion/Immunofluorescence.

Reported

In 10 days

Reference Interval

Component Sex Alpha
ANTI-CENTROMERE ANTIBODY M/F NEGATIVE
ANTI-SCL 70 ANTIBODY M/F NEGATIVE

Performed by

PCL Clinical Laboratory

CPT Codes

86235; 86255

Collection

LAB5140 Anti-SCL-70

LAB4570 Anti-Centromere

Collect

5.0 mL, gold or red top with gel (SST), (clot activator serum).

Unacceptable Conditions

Excessive hemolysis, chylous serum, gross contamination, inadequate volume of blood, inadequate patient and/or specimen identification.

Storage/Transport Temperature

Internal: Deliver to lab immediately
Offsite: 2 mL Separate serum from cells and deliver to the lab refrigerated.

Stability (from collection to initiation)

Refrigerated: 1-2 weeks; Frozen: Indefinitely.

Remarks

Serum must be removed from clot within 2 hours after collection. Refrigerate.

Performed by

PCL Clinical Laboratory

Ordering

Performed

Mon - Fri

Methodology

Immunodiffusion/Immunofluorescence.

Reported

In 10 days

Result Interpretation

Reference Interval

Component Sex Alpha
ANTI-CENTROMERE ANTIBODY M/F NEGATIVE
ANTI-SCL 70 ANTIBODY M/F NEGATIVE

Performed by

PCL Clinical Laboratory

Administrative

CPT Codes

86235; 86255

ANTI-SMITH, ANTI-N-RNP

New Individual Ordering(Beaker):

LAB4559 ANTI-SMITH

LAB4803 ANTI-NRNP

Collect

One 7 ml red top with gel

Unacceptable Conditions

Grossly hemolysed, serum too warm, improperly identified specimen.

Storage/Transport Temperature

Internal: Deliver to lab immediately
Offsite: 1 mL serum Separate serum from cells and deliver to the lab refrigerated.

Stability (from collection to initiation)

Refrigerated: 1-2 weeks; Frozen: Indefinitely.

Remarks

Remove serum from clot within 2 hours after drawing. Refrigerate specimen.

Performed by

PCL Clinical Laboratory

Performed

Mon - Fri

Methodology

Immunodiffusion [ID]

Reported

In 3 days

Synonyms

  • ENA Ab
  • U1-RNP Antibodies
  • -251 Anti-Smith/n-RNP Antibody
  • ANTI-U1-RNP Antibodies
  • Extractable Nuclear Antigen Ab
  • LAB852

Performed by

PCL Clinical Laboratory

CPT Codes

86235 (2)

Collection

New Individual Ordering(Beaker):

LAB4559 ANTI-SMITH

LAB4803 ANTI-NRNP

Collect

One 7 ml red top with gel

Unacceptable Conditions

Grossly hemolysed, serum too warm, improperly identified specimen.

Storage/Transport Temperature

Internal: Deliver to lab immediately
Offsite: 1 mL serum Separate serum from cells and deliver to the lab refrigerated.

Stability (from collection to initiation)

Refrigerated: 1-2 weeks; Frozen: Indefinitely.

Remarks

Remove serum from clot within 2 hours after drawing. Refrigerate specimen.

Performed by

PCL Clinical Laboratory

Ordering

Performed

Mon - Fri

Methodology

Immunodiffusion [ID]

Reported

In 3 days

Synonyms

  • ENA Ab
  • U1-RNP Antibodies
  • -251 Anti-Smith/n-RNP Antibody
  • ANTI-U1-RNP Antibodies
  • Extractable Nuclear Antigen Ab
  • LAB852
Result Interpretation

Performed by

PCL Clinical Laboratory

Administrative

CPT Codes

86235 (2)

ANTI-SSA

LAB344

Collect

One 4.5 mL Red or Gold top tube with gel separator (SST).

Pediatric Collection

1 mL serum.

Unacceptable Conditions

Grossly hemolysed, serum too warm, improperly identified specimen.

Stability (from collection to initiation)

Refrigerated: 1-2 weeks; Frozen: Indefinitely.

Performed by

PCL Clinical Laboratory

Performed

Mon - Fri

Methodology

ELISA

Synonyms

  • Ro Autoantibodies
  • Anti-Ro Antibodies
  • Anti-Ro
  • Sjogren's Syndrome Antibody
  • LAB344
  • SSA ANTIBODIES

Reference Interval

NEGATIVE

Performed by

PCL Clinical Laboratory

CPT Codes

86235

Collection

LAB344

Collect

One 4.5 mL Red or Gold top tube with gel separator (SST).

Pediatric Collection

1 mL serum.

Unacceptable Conditions

Grossly hemolysed, serum too warm, improperly identified specimen.

Stability (from collection to initiation)

Refrigerated: 1-2 weeks; Frozen: Indefinitely.

Performed by

PCL Clinical Laboratory

Ordering

Performed

Mon - Fri

Methodology

ELISA

Synonyms

  • Ro Autoantibodies
  • Anti-Ro Antibodies
  • Anti-Ro
  • Sjogren's Syndrome Antibody
  • LAB344
  • SSA ANTIBODIES
Result Interpretation

Reference Interval

NEGATIVE

Performed by

PCL Clinical Laboratory

Administrative

CPT Codes

86235

ANTI-SSA/SSB

New Individual ordering (Beaker):

LAB344 ANTI-SSA

LAB345 ANTI-SSB

Collect

One 4.5 mL Red or Gold top tube with gel separator (SST).

Pediatric Collection

1 mL serum.

Unacceptable Conditions

Grossly hemolysed, serum too warm, improperly identified specimen.

Storage/Transport Temperature

Internal: Deliver to lab immediately.
Offsite: Allow to clot for 30 minutes before centrifuging. Centrifuge within 2 hours of collection. Transport at 2-8 degrees C.

Stability (from collection to initiation)

Refrigerated: 1-2 weeks; Frozen: Indefinitely.

Performed by

PCL Clinical Laboratory

Performed

Mon - Fri dayshift

Methodology

ELISA/Immunodiffusion [ID]

Reported

In 3 days

Synonyms

  • Sjogren's Syndrome Antibodies
  • -274 Anti-SSA & SSB Antibodies
  • SSA ANTIBODIES/SSB ANTIBODIES
  • LAB3472

Reference Interval

Anti-SSA: Negative

 

Anti-SSB: Negative

Performed by

PCL Clinical Laboratory

CPT Codes

86235 (2)

Collection

New Individual ordering (Beaker):

LAB344 ANTI-SSA

LAB345 ANTI-SSB

Collect

One 4.5 mL Red or Gold top tube with gel separator (SST).

Pediatric Collection

1 mL serum.

Unacceptable Conditions

Grossly hemolysed, serum too warm, improperly identified specimen.

Storage/Transport Temperature

Internal: Deliver to lab immediately.
Offsite: Allow to clot for 30 minutes before centrifuging. Centrifuge within 2 hours of collection. Transport at 2-8 degrees C.

Stability (from collection to initiation)

Refrigerated: 1-2 weeks; Frozen: Indefinitely.

Performed by

PCL Clinical Laboratory

Ordering

Performed

Mon - Fri dayshift

Methodology

ELISA/Immunodiffusion [ID]

Reported

In 3 days

Synonyms

  • Sjogren's Syndrome Antibodies
  • -274 Anti-SSA & SSB Antibodies
  • SSA ANTIBODIES/SSB ANTIBODIES
  • LAB3472
Result Interpretation

Reference Interval

Anti-SSA: Negative

 

Anti-SSB: Negative

Performed by

PCL Clinical Laboratory

Administrative

CPT Codes

86235 (2)

ANTI-SSB

LAB345

Collect

5.0 mL, gold or red top with gel (SST), (clot activator serum).

Pediatric Collection

1 mL serum

Unacceptable Conditions

Grossly hemolysed, serum too warm, improperly identified specimen.

Storage/Transport Temperature

Internal: Deliver to lab immediately
Offsite: 2 mL Separate serum from cells and deliver to the lab refrigerated.

Stability (from collection to initiation)

Refrigerated: 1-2 weeks; Frozen: Indefinitely.

Remarks

Separate serum from clot within 2 hours after collection and refrigerate.

Performed by

PCL Clinical Laboratory

Performed

Mon - Fri

Methodology

Immunodiffusion [ID]

Reported

In 3 days

Synonyms

  • Anti-La
  • Anti-La Antibodies
  • LAB345
  • SSB ANTIBODIES

Reference Interval

NEGATIVE

Performed by

PCL Clinical Laboratory

CPT Codes

86235

Collection

LAB345

Collect

5.0 mL, gold or red top with gel (SST), (clot activator serum).

Pediatric Collection

1 mL serum

Unacceptable Conditions

Grossly hemolysed, serum too warm, improperly identified specimen.

Storage/Transport Temperature

Internal: Deliver to lab immediately
Offsite: 2 mL Separate serum from cells and deliver to the lab refrigerated.

Stability (from collection to initiation)

Refrigerated: 1-2 weeks; Frozen: Indefinitely.

Remarks

Separate serum from clot within 2 hours after collection and refrigerate.

Performed by

PCL Clinical Laboratory

Ordering

Performed

Mon - Fri

Methodology

Immunodiffusion [ID]

Reported

In 3 days

Synonyms

  • Anti-La
  • Anti-La Antibodies
  • LAB345
  • SSB ANTIBODIES
Result Interpretation

Reference Interval

NEGATIVE

Performed by

PCL Clinical Laboratory

Administrative

CPT Codes

86235

ANTITHROMBIN ACTIVITY

LAB311

AT3

Collect

One 2.7 mL blue top (3.2% sodium citrate).

Also acceptable: One 1.8 mL blue top tube (3.2% sodium citrate).

All blue top tubes collected for coagulation assays that do not have a blood culture collected first must have a discard tube collected prior to filling. The discard tube should be another blue top tube in which greater than 1 mL of blood is collected.

Pediatric Collection

0.5 mL of platelet poor plasma.

Unacceptable Conditions

Clotted sample; tube fill volume less than 90% or greater than 110%; more than 4 hours since collection; sample not properly identified; incorrect container; insufficient sample volume.

Storage/Transport Temperature

Internal: Deliver to lab immediately.
Offsite:  Separate plasma from cells as soon as possible. Place plasma in an aliquot container and transport to lab frozen.

Stability (from collection to initiation)

Whole blood: Ambient, 4 hours.

Platelet poor plasma:  Ambient, 4 hours; Refrigerated, 4 hours; Frozen (-20 degrees C), 2 weeks; Frozen (-70 degrees C), 6 months.

Remarks

Reference range established using 3.2% sodium citrate. Patient history is helpful for interpretation of result. Antithrombin III deficiency may be due to a congenital deficiency or one of many acquired conditions (ie; post-thrombotic phenomena, consumptive coagulopathy, liver dysfunction, heparin therapy , or renal disease).

Performed by

PCL Clinical Laboratory - Coagulation

Performed

Daily

Methodology

Chromogenic assay

Reported

Same day

Synonyms

  • ATIII
  • AT3
  • ANTITHROMBIN III ACTIVITY

Reference Interval

72.0 - 125.0 U/dL

Performed by

PCL Clinical Laboratory - Coagulation

CPT Codes

85300

Collection

LAB311

AT3

Collect

One 2.7 mL blue top (3.2% sodium citrate).

Also acceptable: One 1.8 mL blue top tube (3.2% sodium citrate).

All blue top tubes collected for coagulation assays that do not have a blood culture collected first must have a discard tube collected prior to filling. The discard tube should be another blue top tube in which greater than 1 mL of blood is collected.

Pediatric Collection

0.5 mL of platelet poor plasma.

Unacceptable Conditions

Clotted sample; tube fill volume less than 90% or greater than 110%; more than 4 hours since collection; sample not properly identified; incorrect container; insufficient sample volume.

Storage/Transport Temperature

Internal: Deliver to lab immediately.
Offsite:  Separate plasma from cells as soon as possible. Place plasma in an aliquot container and transport to lab frozen.

Stability (from collection to initiation)

Whole blood: Ambient, 4 hours.

Platelet poor plasma:  Ambient, 4 hours; Refrigerated, 4 hours; Frozen (-20 degrees C), 2 weeks; Frozen (-70 degrees C), 6 months.

Remarks

Reference range established using 3.2% sodium citrate. Patient history is helpful for interpretation of result. Antithrombin III deficiency may be due to a congenital deficiency or one of many acquired conditions (ie; post-thrombotic phenomena, consumptive coagulopathy, liver dysfunction, heparin therapy , or renal disease).

Performed by

PCL Clinical Laboratory - Coagulation

Ordering

Performed

Daily

Methodology

Chromogenic assay

Reported

Same day

Synonyms

  • ATIII
  • AT3
  • ANTITHROMBIN III ACTIVITY
Result Interpretation

Reference Interval

72.0 - 125.0 U/dL

Performed by

PCL Clinical Laboratory - Coagulation

Administrative

CPT Codes

85300

APOLIPOPROTEIN A1

LAB3139

Collect

Serum separator tube.

Patient Preparation

Freshly drawn fasting specimen.

Specimen Preparation

Separate serum from cells ASAP or within 2 hours of collection. Transfer 1 mL serum to an ARUP Standard Transport Tube. (Min: 0.5 mL)

Unacceptable Conditions

Hemolyzed specimens.

Storage/Transport Temperature

Refrigerated.

Stability (from collection to initiation)

After separation from cells: Ambient: 8 hours; Refrigerated: 8 days; Frozen: 3 months

Remarks

Separate serum from cells ASAP.

Notes

This protein is found in high density lipoprotein.

Performed

Sun-Sat

Methodology

Quantitative Nephelometry

Reported

Within 24 hours

Synonyms

  • High Density Lipoprotein, A-1
  • LAB3139
  • APO A-1

Ordering Recommendations

Not recommended for cardiovascular disease risk assessment. Use to detect the very rare familial alpha-lipoprotein deficiency.

Reference Interval

Male: 94-178 mg/dL
Female: 101-199 mg/dL

CPT Codes

82172
Collection

LAB3139

Collect

Serum separator tube.

Patient Preparation

Freshly drawn fasting specimen.

Specimen Preparation

Separate serum from cells ASAP or within 2 hours of collection. Transfer 1 mL serum to an ARUP Standard Transport Tube. (Min: 0.5 mL)

Unacceptable Conditions

Hemolyzed specimens.

Storage/Transport Temperature

Refrigerated.

Stability (from collection to initiation)

After separation from cells: Ambient: 8 hours; Refrigerated: 8 days; Frozen: 3 months

Remarks

Separate serum from cells ASAP.

Notes

This protein is found in high density lipoprotein.
Ordering

Performed

Sun-Sat

Methodology

Quantitative Nephelometry

Reported

Within 24 hours

Synonyms

  • High Density Lipoprotein, A-1
  • LAB3139
  • APO A-1

Ordering Recommendations

Not recommended for cardiovascular disease risk assessment. Use to detect the very rare familial alpha-lipoprotein deficiency.
Result Interpretation

Reference Interval

Male: 94-178 mg/dL
Female: 101-199 mg/dL
Administrative

CPT Codes

82172

APOLIPOPROTEIN B

LAB3144

Collect

Serum separator tube.

Patient Preparation

Fasting specimen.

Specimen Preparation

Separate serum from cells ASAP or within 2 hours of collection. Transfer 1 mL serum to an ARUP Standard Transport Tube. (Min: 0.5 mL)

Unacceptable Conditions

Hemolyzed specimens.

Storage/Transport Temperature

Refrigerated.

Stability (from collection to initiation)

After separation from cells: Ambient: 8 hours; Refrigerated: 8 days; Frozen: 3 months

Notes

This protein is found in low density lipoprotein.

Performed

Sun-Sat

Methodology

Quantitative Nephelometry

Reported

Within 24 hours

Synonyms

  • Low Density Lipoprotein, B
  • LAB3144
  • APO B-100

Ordering Recommendations

Acceptable non-traditional secondary cardiovascular disease risk screen for specific populations.

Reference Interval

Male: 55-140 mg/dL
Female: 55-125 mg/dL

CPT Codes

82172
Collection

LAB3144

Collect

Serum separator tube.

Patient Preparation

Fasting specimen.

Specimen Preparation

Separate serum from cells ASAP or within 2 hours of collection. Transfer 1 mL serum to an ARUP Standard Transport Tube. (Min: 0.5 mL)

Unacceptable Conditions

Hemolyzed specimens.

Storage/Transport Temperature

Refrigerated.

Stability (from collection to initiation)

After separation from cells: Ambient: 8 hours; Refrigerated: 8 days; Frozen: 3 months

Notes

This protein is found in low density lipoprotein.
Ordering

Performed

Sun-Sat

Methodology

Quantitative Nephelometry

Reported

Within 24 hours

Synonyms

  • Low Density Lipoprotein, B
  • LAB3144
  • APO B-100

Ordering Recommendations

Acceptable non-traditional secondary cardiovascular disease risk screen for specific populations.
Result Interpretation

Reference Interval

Male: 55-140 mg/dL
Female: 55-125 mg/dL
Administrative

CPT Codes

82172

APOLIPOPROTEIN E GENOTYPE

LAB3100

Collect

Lavender (EDTA), pink (K2EDTA), or yellow (ACD Solution A or B).

Specimen Preparation

Transport 3 mL whole blood. (Min: 1 mL)

Storage/Transport Temperature

Refrigerated.

Stability (from collection to initiation)

Ambient: 72 hours; Refrigerated: 1 week; Frozen: Unacceptable

Performed by

PCL Clinical Laboratory.

Notes

This test is for cardiovascular risk assessment only and must not be ordered for assessing Alzheimer disease in a demented patient.  Athena Neurosciences, Inc. is the exclusive licensee of U.S. Patent No. 5,508,167 for the Alzheimer risk assessment.

This test is not recommended for nonsymptomatic patients under 18 years of age.

Performed

Mon, Thu

Methodology

Polymerase Chain Reaction/Fluorescence Monitoring

Reported

2-7 days

Synonyms

  • LAB3100
  • ApoLipoprotein E Genotype
  • ApoE cardiac risk
  • ApoE 2 mutations
  • APOE
  • APO E Cardiac Risk

Ordering Recommendations

Use to detect APOE mutations in individuals with a suspicion of type III hyperlipoproteinemia (familial hyperlipoproteinemia).

Reference Interval

Homozygous apo e3 (e3/e3): This genotype is the most common (normal) genotype.

Interpretive Data

Background Information for Apolipoprotein E (APOE) 2 Mutations, Cardiovascular Risk
Characteristics: Hyperlipoproteinemia III (HPL III) is characterized by increased cholesterol and triglyceride levels, presence of B-VLDL, xanthomas, and premature vascular disease including coronary heart disease (CHD) and peripheral artery disease.
Incidence of HPL III: Approximately 1 in 5,000.
Inheritance: Autosomal recessive.
Penetrance: 1 to 5 percent of individuals homozygous for the E2 allele and 26 percent of those heterozygous for both E2 and familial hypercholesterolemia will develop symptoms.
Cause: The E2 isoform binds the lipoprotein receptors with only 2 percent of the affinity of E3 and E4 resulting in impaired clearance of chylomicron and VLDL remnants and increased plasma cholesterol and triglyceride levels. 
Mutations Tested: E2, E3 (normal) and E4 alleles of the apolipoprotein E gene.
Clinical Sensitivity: About 5 percent of individuals with premature CHD are homozygous for E2.
Methodology: Polymerase chain reaction (PCR) and fluorescence monitoring using hybridization probes.
Analytical Sensitivity and Specificity: 99 percent.
Limitations: Rare isoforms of APOE will not be detected. If rare alleles are suspected, phenotyping by isoelectric focusing may be indicated. Diagnostic errors can occur due to rare sequence variations.

This test is performed pursuant to an agreement with Roche Molecular Systems, Inc.

Performed by

PCL Clinical Laboratory.

CPT Codes

81401

 
Collection

LAB3100

Collect

Lavender (EDTA), pink (K2EDTA), or yellow (ACD Solution A or B).

Specimen Preparation

Transport 3 mL whole blood. (Min: 1 mL)

Storage/Transport Temperature

Refrigerated.

Stability (from collection to initiation)

Ambient: 72 hours; Refrigerated: 1 week; Frozen: Unacceptable

Performed by

PCL Clinical Laboratory.

Notes

This test is for cardiovascular risk assessment only and must not be ordered for assessing Alzheimer disease in a demented patient.  Athena Neurosciences, Inc. is the exclusive licensee of U.S. Patent No. 5,508,167 for the Alzheimer risk assessment.

This test is not recommended for nonsymptomatic patients under 18 years of age.
Ordering

Performed

Mon, Thu

Methodology

Polymerase Chain Reaction/Fluorescence Monitoring

Reported

2-7 days

Synonyms

  • LAB3100
  • ApoLipoprotein E Genotype
  • ApoE cardiac risk
  • ApoE 2 mutations
  • APOE
  • APO E Cardiac Risk

Ordering Recommendations

Use to detect APOE mutations in individuals with a suspicion of type III hyperlipoproteinemia (familial hyperlipoproteinemia).
Result Interpretation

Reference Interval

Homozygous apo e3 (e3/e3): This genotype is the most common (normal) genotype.

Interpretive Data

Background Information for Apolipoprotein E (APOE) 2 Mutations, Cardiovascular Risk
Characteristics: Hyperlipoproteinemia III (HPL III) is characterized by increased cholesterol and triglyceride levels, presence of B-VLDL, xanthomas, and premature vascular disease including coronary heart disease (CHD) and peripheral artery disease.
Incidence of HPL III: Approximately 1 in 5,000.
Inheritance: Autosomal recessive.
Penetrance: 1 to 5 percent of individuals homozygous for the E2 allele and 26 percent of those heterozygous for both E2 and familial hypercholesterolemia will develop symptoms.
Cause: The E2 isoform binds the lipoprotein receptors with only 2 percent of the affinity of E3 and E4 resulting in impaired clearance of chylomicron and VLDL remnants and increased plasma cholesterol and triglyceride levels. 
Mutations Tested: E2, E3 (normal) and E4 alleles of the apolipoprotein E gene.
Clinical Sensitivity: About 5 percent of individuals with premature CHD are homozygous for E2.
Methodology: Polymerase chain reaction (PCR) and fluorescence monitoring using hybridization probes.
Analytical Sensitivity and Specificity: 99 percent.
Limitations: Rare isoforms of APOE will not be detected. If rare alleles are suspected, phenotyping by isoelectric focusing may be indicated. Diagnostic errors can occur due to rare sequence variations.

This test is performed pursuant to an agreement with Roche Molecular Systems, Inc.

Performed by

PCL Clinical Laboratory.

Administrative

CPT Codes

81401

 

APTT CORRECTION

LAB326

APTT,MIX

Collect

One 2.7 mL blue top (3.2% sodium citrate).

Also acceptable: One 1.8 mL blue top tube (3.2% sodium citrate).

All blue tops collected for coagulation assays which do not have a blood culture collected first must have a discard tube collected prior to filling.  Discard tube should be another blue top in which greater than 1 mL of blood is collected.

Pediatric Collection

0.5 mL of platelet poor plasma.

Unacceptable Conditions

Clotted sample; tube fill volume less than 70% or greater than 110%; more than 4 hours after collection; sample not properly identified; incorrect container; insufficient sample volume.

Storage/Transport Temperature

Internal: Deliver to lab immediately.
Offsite:  Separate plasma from cells as soon as possible. Place plasma in an aliquot container and transport to lab frozen.

Stability (from collection to initiation)

Whole blood: Ambient, 4 hours.

Platelet poor plasma aliquot: Ambient, 4 hours; Refrigerated, 4 hours; Frozen (-20 degrees C), 2 weeks; Frozen (-70 degrees C), 6 months.

Remarks

The PTT Correction will not be performed for PTTs less than 38 seconds.   PTTs between 34 and 38 are generally not indicative of clinically significant coagulation factor deficiencies.  If there is clinical suspicion of mild hemophilia, appropriate factor assays should be ordered.

Performed by

PCL Clinical Laboratory - Specials (Coagulation)

Performed

Daily

Methodology

Mechanical clot detection

Reported

Same day

Synonyms

  • PTT Mixing Study
  • Mixing Study
  • PTT Mix
  • APTT,MIX

Reference Interval

27.6 - 34.1 seconds

Performed by

PCL Clinical Laboratory - Specials (Coagulation)

CPT Codes

85732

Collection

LAB326

APTT,MIX

Collect

One 2.7 mL blue top (3.2% sodium citrate).

Also acceptable: One 1.8 mL blue top tube (3.2% sodium citrate).

All blue tops collected for coagulation assays which do not have a blood culture collected first must have a discard tube collected prior to filling.  Discard tube should be another blue top in which greater than 1 mL of blood is collected.

Pediatric Collection

0.5 mL of platelet poor plasma.

Unacceptable Conditions

Clotted sample; tube fill volume less than 70% or greater than 110%; more than 4 hours after collection; sample not properly identified; incorrect container; insufficient sample volume.

Storage/Transport Temperature

Internal: Deliver to lab immediately.
Offsite:  Separate plasma from cells as soon as possible. Place plasma in an aliquot container and transport to lab frozen.

Stability (from collection to initiation)

Whole blood: Ambient, 4 hours.

Platelet poor plasma aliquot: Ambient, 4 hours; Refrigerated, 4 hours; Frozen (-20 degrees C), 2 weeks; Frozen (-70 degrees C), 6 months.

Remarks

The PTT Correction will not be performed for PTTs less than 38 seconds.   PTTs between 34 and 38 are generally not indicative of clinically significant coagulation factor deficiencies.  If there is clinical suspicion of mild hemophilia, appropriate factor assays should be ordered.

Performed by

PCL Clinical Laboratory - Specials (Coagulation)

Ordering

Performed

Daily

Methodology

Mechanical clot detection

Reported

Same day

Synonyms

  • PTT Mixing Study
  • Mixing Study
  • PTT Mix
  • APTT,MIX
Result Interpretation

Reference Interval

27.6 - 34.1 seconds

Performed by

PCL Clinical Laboratory - Specials (Coagulation)

Administrative

CPT Codes

85732

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