VARICELLA ZOSTER AB IGM (CSF)

LAB3340

Collect

CSF.

Specimen Preparation

Transfer 0.5 mL CSF to an ARUP Standard Transport Tube. (Min: 0.3 mL)

Unacceptable Conditions

Specimen types other than CSF. Contaminated or heat-inactivated specimens.

Storage/Transport Temperature

Refrigerated.

Stability (from collection to initiation)

Ambient: 8 hours; Refrigerated: 2 weeks; Frozen: 1 year

Performed

Mon-Fri

Methodology

Semi-Quantitative Enzyme-Linked Immunosorbent Assay

Reported

1-5 days

Synonyms

  • VZV IgM CSF
  • LAB3340
  • VZV IGM

Ordering Recommendations

Not recommended. Refer to Varicella-Zoster Virus by PCR (0060042) or Meningitis/Encephalitis Panel by PCR (2013305).

Reference Interval

0.90 ISR or less: Negative - No significant level of IgM antibody to varicella-zoster virus detected.
0.91-1.09 ISR: Equivocal - Repeat testing in 10-14 days may be helpful.
1.10 ISR or greater: Positive - Significant level of IgM antibody to varicella-zoster virus detected, which may indicate current or recent infection. However, low levels of IgM antibodies may occasionally persist for more than 12 months post-infection.

Interpretive Data

The detection of antibodies to varicella-zoster in CSF may indicate central nervous system infection.  However, consideration must be given to possible contamination by blood or transfer of serum antibodies across the blood-brain barrier.

CPT Codes

86787
Collection

LAB3340

Collect

CSF.

Specimen Preparation

Transfer 0.5 mL CSF to an ARUP Standard Transport Tube. (Min: 0.3 mL)

Unacceptable Conditions

Specimen types other than CSF. Contaminated or heat-inactivated specimens.

Storage/Transport Temperature

Refrigerated.

Stability (from collection to initiation)

Ambient: 8 hours; Refrigerated: 2 weeks; Frozen: 1 year
Ordering

Performed

Mon-Fri

Methodology

Semi-Quantitative Enzyme-Linked Immunosorbent Assay

Reported

1-5 days

Synonyms

  • VZV IgM CSF
  • LAB3340
  • VZV IGM

Ordering Recommendations

Not recommended. Refer to Varicella-Zoster Virus by PCR (0060042) or Meningitis/Encephalitis Panel by PCR (2013305).
Result Interpretation

Reference Interval

0.90 ISR or less: Negative - No significant level of IgM antibody to varicella-zoster virus detected.
0.91-1.09 ISR: Equivocal - Repeat testing in 10-14 days may be helpful.
1.10 ISR or greater: Positive - Significant level of IgM antibody to varicella-zoster virus detected, which may indicate current or recent infection. However, low levels of IgM antibodies may occasionally persist for more than 12 months post-infection.

Interpretive Data

The detection of antibodies to varicella-zoster in CSF may indicate central nervous system infection.  However, consideration must be given to possible contamination by blood or transfer of serum antibodies across the blood-brain barrier.

Administrative

CPT Codes

86787

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