VANCOMYCIN PEAK

LAB41

VANC P

Collect

One 4.5 mL Green top tube with gel separator (PST).

Pediatric Collection

1.5 mL whole blood or 20 capillary tubes.

Unacceptable Conditions

Sample not properly identified; incorrect container; insufficient sample volume.

Storage/Transport Temperature

Internal: Deliver to lab immediately
Offsite: Centrifuge within 30 minutes of collection. Send at 2-8 degrees C if tested within 24 hours. Place plasma in aliquot container and send frozen if not tested within 24 hours.

Stability (from collection to initiation)

Refrigerated: 24 hours; Frozen (-20 degrees C): Greater than 24 hours

Remarks

Include dosage information. Draw peak levels 1-2 hours after the end of a 60 minute infusion. Random levels are not necessary for patients with normal renal function and appropriate peak levels.

Performed by

PCL Clinical Laboratory - Core

Performed

Daily

Methodology

Enzymatic

Reported

Same day

Synonyms

  • LAB41

Reference Interval

20.0-40.0 ug/mL

Interpretive Data

Reported peak therapeutic ranges for vancomycin vary considerably. Both the dosage regimen  and  the  timing  of  sample  collection  may  affect  the  peak  therapeutic  range.  For  patients  on  concomitant  vancomycin  and  aminoglycoside  treatment,  peak  vancomycin concentrations  exceeding  30  μg/mL  are  associated  with  nephrotoxicity.  Serum concentrations above 80 μg/mL are associated with ototoxicity.   For effective treatment, some patients may require serum or plasma levels outside these ranges. Therefore,  the  expected  ranges  are  provided  only  as general guidance,  and  individual  patient  results should be interpreted in light of clinical signs and symptoms.

Performed by

PCL Clinical Laboratory - Core

CPT Codes

80202

Collection

LAB41

VANC P

Collect

One 4.5 mL Green top tube with gel separator (PST).

Pediatric Collection

1.5 mL whole blood or 20 capillary tubes.

Unacceptable Conditions

Sample not properly identified; incorrect container; insufficient sample volume.

Storage/Transport Temperature

Internal: Deliver to lab immediately
Offsite: Centrifuge within 30 minutes of collection. Send at 2-8 degrees C if tested within 24 hours. Place plasma in aliquot container and send frozen if not tested within 24 hours.

Stability (from collection to initiation)

Refrigerated: 24 hours; Frozen (-20 degrees C): Greater than 24 hours

Remarks

Include dosage information. Draw peak levels 1-2 hours after the end of a 60 minute infusion. Random levels are not necessary for patients with normal renal function and appropriate peak levels.

Performed by

PCL Clinical Laboratory - Core

Ordering

Performed

Daily

Methodology

Enzymatic

Reported

Same day

Synonyms

  • LAB41
Result Interpretation

Reference Interval

20.0-40.0 ug/mL

Interpretive Data

Reported peak therapeutic ranges for vancomycin vary considerably. Both the dosage regimen  and  the  timing  of  sample  collection  may  affect  the  peak  therapeutic  range.  For  patients  on  concomitant  vancomycin  and  aminoglycoside  treatment,  peak  vancomycin concentrations  exceeding  30  μg/mL  are  associated  with  nephrotoxicity.  Serum concentrations above 80 μg/mL are associated with ototoxicity.   For effective treatment, some patients may require serum or plasma levels outside these ranges. Therefore,  the  expected  ranges  are  provided  only  as general guidance,  and  individual  patient  results should be interpreted in light of clinical signs and symptoms.

Performed by

PCL Clinical Laboratory - Core

Administrative

CPT Codes

80202

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