BETA-2 TRANSFERRIN

LAB205

Collect

Aural or nasal fluid in sterile container.

Specimen Preparation

Do not freeze.   Transport 2 mL aural or nasal fluid in a tube without preservative. (Min: 1 mL aural or nasal fluid)

Storage/Transport Temperature

Refrigerated.

Stability (from collection to initiation)

Ambient: 4 hours; Refrigerated: 72 hours; Frozen: Unacceptable

Notes

The beta-2 transferrin protein assay by IFE methodology is not a reliable method for detecting human perilymph due to the low sensitivity of the assay.

Performed

Sun-Sat

Methodology

Qualitative Immunofixation Electrophoresis

Reported

1-4 days

Synonyms

  • Transferrin, Beta-2
  • LAB205
  • B2TRNSF

Ordering Recommendations

Aids in diagnosis of CSF leak.

Reference Interval

None detected

Interpretive Data

Detection of a beta-2 transferrin band by IFE is diagnostic for the presence of cerebrospinal fluid (CSF). This test is useful in the differential diagnosis for CSF otorrhea or CSF rhinorrhea. Beta-2 transferrin is not detected by this methodology in normal serum, tears, saliva, sputum, nasal, or aural fluid.

The performance characteristics of this test were determined by PCL Clinical Laboratory, Inc.

CPT Codes

86335
Collection

LAB205

Collect

Aural or nasal fluid in sterile container.

Specimen Preparation

Do not freeze.   Transport 2 mL aural or nasal fluid in a tube without preservative. (Min: 1 mL aural or nasal fluid)

Storage/Transport Temperature

Refrigerated.

Stability (from collection to initiation)

Ambient: 4 hours; Refrigerated: 72 hours; Frozen: Unacceptable

Notes

The beta-2 transferrin protein assay by IFE methodology is not a reliable method for detecting human perilymph due to the low sensitivity of the assay.
Ordering

Performed

Sun-Sat

Methodology

Qualitative Immunofixation Electrophoresis

Reported

1-4 days

Synonyms

  • Transferrin, Beta-2
  • LAB205
  • B2TRNSF

Ordering Recommendations

Aids in diagnosis of CSF leak.
Result Interpretation

Reference Interval

None detected

Interpretive Data

Detection of a beta-2 transferrin band by IFE is diagnostic for the presence of cerebrospinal fluid (CSF). This test is useful in the differential diagnosis for CSF otorrhea or CSF rhinorrhea. Beta-2 transferrin is not detected by this methodology in normal serum, tears, saliva, sputum, nasal, or aural fluid.

The performance characteristics of this test were determined by PCL Clinical Laboratory, Inc.

Administrative

CPT Codes

86335

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